The disease begins 6-40 days after mosquito bites, with fever and chills and muscle aches, depending on the exact pathogen. The fever is very high (40-41 ° C), usually accompanied by vomiting and abdominal pain, followed by heavy sweating. Such febrile attacks - also depending on the pathogen - recur every 48-72 hours (the old name for malaria is alternating fever). Enlarged, marked anemia of the liver and spleen (pale white tendon of the eye) is seen. Urine may be dark yellow in color. If left untreated, the patient can suffer life-threatening brain and kidney damage. It is always treated with accurate knowledge of the pathogen's plasmodium species. The most commonly used drugs in the treatment of malaria: chloroquin, mefloquine, doxycycline, clindamycin.