Tolerance is generally not acquired to: A. Antisecretory action of atropine B. Sedative action of chlorpromazine C. Emetic action of levodopa D. Vasodilator action of nitrates

1 Answer

Answer :

A. Antisecretory action of atropine

Related questions

Description : Tolerance is generally not acquired to: A. Antisecretory action of atropine B. Sedative action of chlorpromazine C. Emetic action of levodopa D. Vasodilator action of nitrates

Last Answer : A. Antisecretory action of atropine

Description : Interaction between the following pair of drugs can be avoided by making suitable adjustments: A. Levodopa and metoclopramide B. Furosemide and indomethacin C. Tetracyclines and ferrous sulfate D. Clonidine and chlorpromazine

Last Answer : C. Tetracyclines and ferrous sulfate

Description : Which of the following drugs acts by inhibiting an enzyme in the body: A. Atropine B. Allopurinol C. Levodopa D. Metoclopramide

Last Answer : B. Allopurinol

Description : Which racial difference in response to drugs has been mentioned incorrectly below: A. Africans require higher concentration of atropine to dilate pupils B. Black races are more responsive ... SMON due to halogenated hydroxyquinolines D. Chloramphenicol induced aplastic anaemia is rare among Indians

Last Answer : B. Black races are more responsive to antihypertensive action of beta blockers

Description : Use of an emetic to remove the ingested poison is contraindicated in following poisonings except that by: A. Strychnine B. Caustic soda C. Ferrous sulfate D. Kerosene

Last Answer : C. Ferrous sulfate

Description : Use of an emetic to remove the ingested poison is contraindicated in following poisonings except that by: A. Strychnine B. Caustic soda C. Ferrous sulfate D. Kerosene

Last Answer : C. Ferrous sulfate

Description : Children are more susceptible than adults to the following action of atropine: A. Tachycardia producing B. Cycloplegic C. Gastric antisecretory D. Central excitant and hyperthermic

Last Answer : D. Central excitant and hyperthermic

Description : Children are more susceptible than adults to the following action of atropine: A. Tachycardia producing B. Cycloplegic C. Gastric antisecretory D. Central excitant and hyperthermic

Last Answer : D. Central excitant and hyperthermic

Description : Significant tolerance does not develop to the following action of morphine: A. Analgesia B. Euphoria C. Sedation D. Miosis

Last Answer : D. Miosis

Description : Select the drug which can markedly potentiate the vasodilator action of organic nitrates: A. Propranolol B. Fluoxetine C. Hydrochlorothiazide D. Sildenafil

Last Answer : D. Sildenafil

Description : Which adverse drug effect is more common in children than in adults: A. Isoniazid induced neuropathy B. Chlorpromazine induced muscle dystonia C. Digoxin induced cardiac arrhythmia D. Penicillin hypersensitivity

Last Answer : B. Chlorpromazine induced muscle dystonia

Description : Which adverse drug effect is more common in children than in adults: A. Isoniazid induced neuropathy B. Chlorpromazine induced muscle dystonia C. Digoxin induced cardiac arrhythmia D. Penicillin hypersensitivity

Last Answer : B. Chlorpromazine induced muscle dystonia

Description : The following drug adverse effect is specially noted in men compared to women: A. Tardive dyskinesia due to neuroleptics B. Levodopa induced abnormal movements C. Ampicillin induced loose motions D. Ketoconazole induced loss of libido

Last Answer : D. Ketoconazole induced loss of libido

Description : The following drug adverse effect is specially noted in men compared to women: A. Tardive dyskinesia due to neuroleptics B. Levodopa induced abnormal movements C. Ampicillin induced loose motions D. Ketoconazole induced loss of libido

Last Answer : D. Ketoconazole induced loss of libido

Description : Monitoring plasma drug concentration is useful while using: A. Antihypertensive drugs B. Levodopa C. Lithium carbonate D. MAO inhibitors

Last Answer : C. Lithium carbonate

Description : Which of the following is a weakly acidic drug: A. Atropine sulfate B. Chloroquine phosphate C. Ephedrine hydrochloride D. Phenytoin sodium

Last Answer : D. Phenytoin sodium

Description : Which of the following is a weakly acidic drug: A. Atropine sulfate B. Chloroquine phosphate C. Ephedrine hydrochloride D. Phenytoin sodium

Last Answer : D. Phenytoin sodium

Description : Tolerance does not develop to the vasodilator action of sodium nitroprusside while it develops to glyceryl trinitrate because: A. Intact sod. nitroprusside molecule acts like nitric oxide B. Enzymes which ... a long duration of action D. Sod. nitroprusside has additional K+ channel opening action

Last Answer : B. Enzymes which generate nitric oxide from nitroprusside are different

Description : Hydralazine is a directly acting vasodilator, but is not used alone as an antihypertensive because: A. By itself, it is a low efficacy antihypertensive B. Effective doses cause marked ... mechanisms D. It primarily reduces systolic blood pressure with little effect on diastolic blood pressure

Last Answer : C. Tolerance to the antihypertensive action develops early due to counterregulatory mechanisms

Description : The quarternary analogues of belladonna alkaloids are preferred over the natural alkaloids for antisecretory/ antispasmodic indications because: A. They have additional nicotinic receptor blocking activity B. They are ... of CNS and ocular effects D. Dose to dose they are more potent than atropine

Last Answer : C. They are devoid of CNS and ocular effects

Description : The quarternary analogues of belladonna alkaloids are preferred over the natural alkaloids for antisecretory/ antispasmodic indications because: A. They have additional nicotinic receptor blocking activity B. They are ... of CNS and ocular effects D. Dose to dose they are more potent than atropine

Last Answer : C. They are devoid of CNS and ocular effects

Description : Tolerance to the antiparkinsonian action develops most rapidly in the case of: A. Levodopa B. Levodopa + carbidopa C. Amantadine D. Bromocriptine

Last Answer : C. Amantadine

Description : Which of the following is a high potency antipsychotic drug having minimal sedative and autonomic effects and no propensity to cause weight gain: A. Chlorpromazine B. Triflupromazine C. Haloperidol D. Olanzapine

Last Answer : C. Haloperido

Description : Fluphenazine differs from chlorpromazine in the following respects except: A. It has higher antipsychotic efficacy B. It is less sedative C. It is less likely to precipitate seizures in epileptics D. It causes more prominent extrapyramidal side effect

Last Answer : A. It has higher antipsychotic efficacy

Description : If the effect of combination of two drugs is equal to the sum of their individual effects, the two drugs are exhibiting: A. Potentiation B. Synergism C. Cross tolerance D. Antagonism

Last Answer : B. Synergism

Description : If the effect of combination of two drugs is equal to the sum of their individual effects, the two drugs are exhibiting: A. Potentiation B. Synergism C. Cross tolerance D. Antagonism

Last Answer : B. Synergism

Description : Microsomal enzyme induction can be a cause of: A. Tolerance B. Physical dependence C. Psychological dependence D. Idiosyncrasy

Last Answer : A. Tolerance

Description : The following drug is effective in chlorpromazine induced parkinsonism: A. Trihexyphenidyl B. Selegiline C. Bromocriptine D. Levodopa + carbidopa

Last Answer : A. Trihexyphenidyl

Description : The drug which abolishes the therapeutic effect of levodopa in parkinsonism, but not that of levodopacarbidopa combination is: A. Metoclopramide B. Pyridoxine C. Chlorpromazine D. Isoniazid

Last Answer : B. Pyridoxine

Description : The following drug/drugs does/do not produce any overt CNS effect in normal individuals but exert(s) clear cut therapeutic effect at the same dose in the presence of a specific neurological/psychiatric disorder: A. Chlorpromazine B. Levodopa C. Imipramine D. All of the above

Last Answer : B. Levodopa

Description : Interaction between the following pair of drugs can be avoided by making suitable adjustments: A. Levodopa and metoclopramide B. Furosemide and indomethacin C. Tetracyclines and ferrous sulfate D. Clonidine and chlorpromazine

Last Answer : C. Tetracyclines and ferrous sulfate

Description : Which of the following drugs acts by inhibiting an enzyme in the body: A. Atropine B. Allopurinol C. Levodopa D. Metoclopramide

Last Answer : B. Allopurinol

Description : What is true of tolerance occurring in regular opium abusers: A. Tolerance develops to all actions of morphine B. No tolerance occurs to euphoric and sedative actions of morphine C. No ... to constipating and miotic actions of morphine D. Lethal dose of morphine is not significantly increased

Last Answer : C. No tolerance occurs to constipating and miotic actions of morphine

Description : High plasma protein binding: A. Increases volume of distribution of the drug B. Facilitates glomerular filtration of the drug C. Minimises drug interactions D. Generally makes the drug long acting

Last Answer : D. Generally makes the drug long acting

Description : High plasma protein binding: A. Increases volume of distribution of the drug B. Facilitates glomerular filtration of the drug C. Minimises drug interactions D. Generally makes the drug long acting

Last Answer : D. Generally makes the drug long acting

Description : Drugs producing allergic reactions generally act as: A. Complete antigens B. Haptenes C. Antibodies D. Mediators

Last Answer : B. Haptenes

Description : A drug which is generally administered in standard doses without the need for dose individualization is: A. Insulin B. Mebendazole C. Prednisolone D. Digoxin

Last Answer : B. Mebendazole

Description : High plasma protein binding: A. Increases volume of distribution of the drug B. Facilitates glomerular filtration of the drug C. Minimises drug interactions D. Generally makes the drug long acting

Last Answer : D. Generally makes the drug long acting

Description : In congestive heart failure patients: A. Volume of distribution of all drugs is increased B. Hepatic clearance of drugs is unaffected C. Orally administered diuretics may not be effective, but the same may work parenterally D. Inotropic action of digoxin is attenuated

Last Answer : C. Orally administered diuretics may not be effective, but the same may work parenterally

Description : A drug which does not produce any action by itself but decreases the slope of the log dose-response curve and suppresses the maximal response to another drug is a: A. Physiological antagonist B. Competitive antagonist C. Noncompetitive antagonist D. Partial agonist

Last Answer : C. Noncompetitive antagonist

Description : The antidotal action of sodium nitrite in cyanide poisoning is based on: A. Physical antagonism B. Chemical antagonism C. Physiological antagonism D. Noncompetitive antagonism

Last Answer : B. Chemical antagonism

Description : Study of drug-receptor interaction has now shown that: A. Maximal response occurs only when all receptors are occupied by the drug B. Drugs exert an all or none' action on a ... lock and key' structural features D. Properties of affinity' and intrinsic activity' are independently variable

Last Answer : D. Properties of ‘affinity’ and ‘intrinsic activity’ are independently variable

Description : Drugs acting through receptors exhibit the following features except: A. Structural specificity B. High potency C. Competitive antagonism D. Dependence of action on lipophilicity

Last Answer : D. Dependence of action on lipophilicity

Description : A nonvolatile, highly lipid soluble drug is metabolized at a rate of 15% per hour. On intravenous injection it produces general anaesthesia for 10 min. Which process is responsible for termination of ... : A. Metabolism in liver B. Plasma protein binding C. Excretion by kidney D. Redistribution

Last Answer : D. Redistribution

Description : Which of the following drugs is administered by intranasal spray/application for systemic action: A. Phenylephrine B. Desmopressin C. Azelastine D. Beclomethasone dipropionate

Last Answer : B. Desmopressin

Description : Agonistic action on which of the following adrenergic receptors located on ciliary epithelial cells reduces aqueous secretion: A. β1 receptor B. β2 receptor C. α1 receptor D. α2 receptor

Last Answer : D. α2 receptor

Description : Beta adrenergic blockers lower intraocular tension by: A. Down regulating adenylyl cyclase in ciliary body through reduced activation of β2 adrenoceptors B. Constricting ciliary blood vessels ... action on trabecular meshwork D. Reducing aqueous formation unrelated to beta adrenoceptor mediation

Last Answer : A. Down regulating adenylyl cyclase in ciliary body through reduced activation of β2 adrenoceptors

Description : The site of action of miotics for therapeutic effect in angle closure glaucoma is: A. Canal of Schlemm B. Ciliary body C. Ciliary muscle D. Sphincter pupillae muscle

Last Answer : D. Sphincter pupillae muscle

Description : Edrophonium is more suitable for differentiating myasthenic crisis from cholinergic crisis because of its: A. Shorter duration of action B. Longer duration of action C. Direct action on muscle end-plate D. Selective inhibition of true cholinesterase

Last Answer : A. Shorter duration of action

Description : Pyridostigmine differs from neostigmine in that: A. It is more potent orally B. It is longer acting C. It produces less muscarinic side effects D. It does not have any direct action on NM receptors

Last Answer : B. It is longer acting