iTunes can do that. — My opinion: I don’t consider <space>, <Delete>, <Enter>, <M> to be a lot of “key combinations”. So here goes… — 1. Bring up your library of music – not a playlist. 2. Select the first song with your mouse. 3. Hit <space> to start playing the song. 4. Don’t like it, hit the <Delete> key. 5. A dialog pops up asking if you’re sure, hit <Enter>. 6. A second dialog asks how to delete, hit <M> to move it to the trash. 7. Hit <space> to start playing the next song. If you like the current song then: 1–3. Same as above. 4. Hit <↓> to select the next song. 5. Hit <space> to start playing that song. — There’s no automatic 45 second timing interval in that scenario. But I’d think this way would be better. You can proceed as fast or as slow as you want. — If you accidentally delete something, simply pull it out of the trash and then drag it back to your iTunes library for re-import.