What is its biological importance?

What is its biological importance?
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LT B4 is produced in neutrophils, it is the most potent chemotactic agent. The slow reacting substance of anaphylaxis (SRS-A) contains LTC4, LTD4 and LTE4. They cause smooth muscle contraction, constrict the bronchioles, increase capillary permeability and produce vasoconstriction.
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