(2) Cattle and sheep Explanation: Foot-and-mouth disease is an infectious and sometimes fatal viral disease that affects cloven-hoofed animals, including domestic and wild bovids. The virus causes a high fever for two or three days, followed by blisters inside the mouth and on the feet that may rupture and cause lameness. Susceptible animals include cattle, water buffalo, sheep, goats, pigs, antelope, deer, and bison.