Out of 24 mols of ATP formed in TCA cycle, 2 molecules of ATP can be formed at “substrate level” by which of the following reaction ? (A) Citric acid→ Isocitric acid (B) Isocitrate→ Oxaloacetate (C) Succinic acid→ Fumarate (D) Succinylcat→ Succinic acid

Out of 24 mols of ATP formed in TCA cycle, 2 molecules of ATP can be formed at “substrate level” by which of the following reaction ? (A) Citric acid→ Isocitric acid (B) Isocitrate→ Oxaloacetate (C) Succinic acid→ Fumarate (D) Succinylcat→ Succinic acid
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D
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Related questions

The example of generation of a high energy phosphate at the substrate level in the citric acid cycle is the reaction: (A) Isocitrate α-Ketoglutarate (B) Succinate α-fumarate (C) Malate α-oxaloacetate (D) Succinyl CoA α-Succinate

Description : The example of generation of a high energy phosphate at the substrate level in the citric acid cycle is the reaction: (A) Isocitrate α-Ketoglutarate (B) Succinate α-fumarate (C) Malate α-oxaloacetate (D) Succinyl CoA α-Succinate

Last Answer : Answer : D

All of the following intermediates of citric acid cycle can be formed from amino acids except (A) α-Ketoglutarate (B) Fumarate (C) Malate (D) Oxaloacetate

Description : All of the following intermediates of citric acid cycle can be formed from amino acids except (A) α-Ketoglutarate (B) Fumarate (C) Malate (D) Oxaloacetate

Last Answer : Answer : C

All of the following compounds are intermediates of TCA cycle except (A) Maleate (B) Pyruvate (C) Oxaloacetate (D) Fumarate

Description : All of the following compounds are intermediates of TCA cycle except (A) Maleate (B) Pyruvate (C) Oxaloacetate (D) Fumarate

Last Answer : Answer : B

Oxidative phosphorylation involves (A) Electron transport system (B) Substrate level phosphorylation (C) Reaction catalyzed by succinic thiokinase in TCA cycle (D) None of the above

Description : Oxidative phosphorylation involves (A) Electron transport system (B) Substrate level phosphorylation (C) Reaction catalyzed by succinic thiokinase in TCA cycle (D) None of the above

Last Answer : (A) Electron transport system

All of the following are intermediates of citric acid cycle except (A) Oxalosuccinate (B) Oxaloacetate (C) Pyruvate (D) Fumarate

Description : All of the following are intermediates of citric acid cycle except (A) Oxalosuccinate (B) Oxaloacetate (C) Pyruvate (D) Fumarate

Last Answer : Answer : C

The substance which may be considered to play a catalytic role in citric acid cycle is (A) Oxaloacetate (B) Isocitrate (C) Malate (D) Fumarate

Description : The substance which may be considered to play a catalytic role in citric acid cycle is (A) Oxaloacetate (B) Isocitrate (C) Malate (D) Fumarate

Last Answer : Answer : A

The carrier of the citric acid cycle is (A) Succinate (B) Fumarate (C) Malate (D) Oxaloacetate

Description : The carrier of the citric acid cycle is (A) Succinate (B) Fumarate (C) Malate (D) Oxaloacetate

Last Answer : D

The number of ATP molecules generated for each turn of the citric acid cycle is (A) 8 (B) 12 (C) 24 (D) 38

Description : The number of ATP molecules generated for each turn of the citric acid cycle is (A) 8 (B) 12 (C) 24 (D) 38

Last Answer : Answer : B

The reaction of Kreb’s cycle which does not require cofactor of vitamin B group is (A) Citrate isocitrate (B) α -Ketoglutarate succinate (C) Malate oxaloacetate (D) Succinate fumarate

Description : The reaction of Kreb’s cycle which does not require cofactor of vitamin B group is (A) Citrate isocitrate (B) α -Ketoglutarate succinate (C) Malate oxaloacetate (D) Succinate fumarate

Last Answer : Answer : A

Fluoroacetate inhibits the reaction of citric acid cycle: (A) Isocitrate α-Ketoglutarate (B) Fumarate α-Malate (C) Citrate α-cis-aconitate (D) Succinate α-fumarate

Description : Fluoroacetate inhibits the reaction of citric acid cycle: (A) Isocitrate α-Ketoglutarate (B) Fumarate α-Malate (C) Citrate α-cis-aconitate (D) Succinate α-fumarate

Last Answer : Answer : C

The integrator between the TCA cycle and urea cycle is (A) Fumarate (B) Malate (C) Pyruvate (D) Citrate

Description : The integrator between the TCA cycle and urea cycle is (A) Fumarate (B) Malate (C) Pyruvate (D) Citrate

Last Answer : Answer : A

The number of molecules of ATP produced by the total oxidation of acetyl CoA in TCA cycle is (A) 6 (B) 8 (C) 10 (D) 12

Description : The number of molecules of ATP produced by the total oxidation of acetyl CoA in TCA cycle is (A) 6 (B) 8 (C) 10 (D) 12

Last Answer : D

A compound serving a link between citric acid cycle and urea cycle is (A) Malate (B) Citrate (C) Succinate (D) Fumarate

Description : A compound serving a link between citric acid cycle and urea cycle is (A) Malate (B) Citrate (C) Succinate (D) Fumarate

Last Answer : Answer : D

A substrate for the enzyme aldolase is (A) galactose-6-phosphate (B) isocitric acid (C) Glucose-1-phosphate (D) Fructose 1, 6 diphosphate

Description : A substrate for the enzyme aldolase is (A) galactose-6-phosphate (B) isocitric acid (C) Glucose-1-phosphate (D) Fructose 1, 6 diphosphate

Last Answer : Answer : D

Substrate level phosphorylation in TCA cycle is in step: (A) Isocitrate dehydrogenase (B) Malate dehydrogenase (C) Aconitase (D) Succinate thiokinase

Description : Substrate level phosphorylation in TCA cycle is in step: (A) Isocitrate dehydrogenase (B) Malate dehydrogenase (C) Aconitase (D) Succinate thiokinase

Last Answer : D

A carrier molecule in the citric acid cycle is (A) Acetyl-CoA (B) Citrate (C) Oxaloacetate (D) Malate

Description : A carrier molecule in the citric acid cycle is (A) Acetyl-CoA (B) Citrate (C) Oxaloacetate (D) Malate

Last Answer : Answer : C

The initial step of the citric acid cycle is (A) Conversion of pyruvate to acetyl-CoA (B) Condensation of acetyl-CoA with oxaloacetate (C) Conversion of citrate to isocitrate (D) Formation of α -ketoglutarate catalysed by isocitrate dehydrogenase

Description : The initial step of the citric acid cycle is (A) Conversion of pyruvate to acetyl-CoA (B) Condensation of acetyl-CoA with oxaloacetate (C) Conversion of citrate to isocitrate (D) Formation of α -ketoglutarate catalysed by isocitrate dehydrogenase

Last Answer : Answer : B

Link between glycolysis, Krebs’ cycle and β-oxidation of fatty acid or carbohydrate and fat metabolism is (a) oxaloacetic acid (b) succinic acid (c) citric acid (d) acetyl CoA.

Description : Link between glycolysis, Krebs’ cycle and β-oxidation of fatty acid or carbohydrate and fat metabolism is (a) oxaloacetic acid (b) succinic acid (c) citric acid (d) acetyl CoA.

Last Answer : (d) acetyl CoA.

Which statement is wrong for Krebs’ cycle? (a) There is one point in the cycle where FAD+ is reduced to FADH2. (b) During conversion of succinyl CoA to succinic acid, a molecule of GTP is synthesised. (c) The cycle starts with condensation of acetyl group (acetyl CoA) with pyruvic acid to yield citric acid. (d) There are three points in the cycle where NAD+ is reduced to NADH + H+.

Description : Which statement is wrong for Krebs' cycle? (a) There is one point in the cycle where FAD+ is reduced to FADH2. (b) During conversion of succinyl CoA to succinic acid, a molecule of GTP is synthesised. (c ... citric acid. (d) There are three points in the cycle where NAD+ is reduced to NADH + H+.

Last Answer : (c) The cycle starts with condensation of acetyl group (acetyl CoA) with pyruvic acid to yield citric acid.

Mitochondrial membrane is freely preamble to (A) Pyruvate (B) Malate (C) Oxaloacetate (D) Fumarate

Description : Mitochondrial membrane is freely preamble to (A) Pyruvate (B) Malate (C) Oxaloacetate (D) Fumarate

Last Answer : Answer : B

Active transport of sugar is depressed by the agent: (A) Oxaloacetate (B) Fumarate (C) Malonate (D) Succinate

Description : Active transport of sugar is depressed by the agent: (A) Oxaloacetate (B) Fumarate (C) Malonate (D) Succinate

Last Answer : C

The reaction catalysed by α-ketoglutarate dehydrogenase in the citric acid cycle requires (A) NAD (B) NADP (C) ADP (D) ATP

Description : The reaction catalysed by α-ketoglutarate dehydrogenase in the citric acid cycle requires (A) NAD (B) NADP (C) ADP (D) ATP

Last Answer : Answer : A

TCA cycle starts with the condensation of acetyl group with (A) _____ (B)_____ to yield citric acid.

Description : TCA cycle starts with the condensation of acetyl group with (A) _____ (B)_____ to yield citric acid.

Last Answer : TCA cycle starts with the condensation of acetyl group with (A) _____ (B)_____ to yield citric acid.

TCA cycle starts with the condensation of acetyl group with (A) _____ (B)_____ to yield citric acid.

Description : TCA cycle starts with the condensation of acetyl group with (A) _____ (B)_____ to yield citric acid.

Last Answer : TCA cycle starts with the condensation of acetyl group with (A) _____ (B)_____ to yield citric acid.

The number of substrate level phosphorylations in one turn of citric acid cycle is (a) zero (b) one (c) two (d) three.

Description : The number of substrate level phosphorylations in one turn of citric acid cycle is (a) zero (b) one (c) two (d) three.

Last Answer : (b) one

Substrate-linked phosphorylation occurs in (A) Glycolytic pathway(B) Citric acid cycle (C) Both (A) and (B) (D) None of these

Description : Substrate-linked phosphorylation occurs in (A) Glycolytic pathway(B) Citric acid cycle (C) Both (A) and (B) (D) None of these

Last Answer : Answer : C

If all the enzymes, intermediates and cofactors of the citric acid cycle as well as an excess of the starting substrate acetylCoA are present and functional in an organelle free solution at the appropriate pH, which of the following factors of the citric acid cycle would prove to be rate limiting? (A) Molecular oxygen (B) Half life of enzyme (C) Turnover of intermediates (D) Reduction of cofactors

Description : If all the enzymes, intermediates and cofactors of the citric acid cycle as well as an excess of the starting substrate acetylCoA are present and functional in an organelle free solution at the appropriate ... oxygen (B) Half life of enzyme (C) Turnover of intermediates (D) Reduction of cofactors

Last Answer : Answer : D

One mol. of Urea is synthesized at the expense of the _______ mols. of ATP. (A) 2 (B) 3 (C) 4 (D) 5

Description : One mol. of Urea is synthesized at the expense of the _______ mols. of ATP. (A) 2 (B) 3 (C) 4 (D) 5

Last Answer : Answer : B

Oxidative degradation of acetyl CoA in the citric acid cycle gives a net yield of all the following except (A) FADH2 (B) 3 NADH (C) 2 ATP (D) 2CO2

Description : Oxidative degradation of acetyl CoA in the citric acid cycle gives a net yield of all the following except (A) FADH2 (B) 3 NADH (C) 2 ATP (D) 2CO2

Last Answer : Answer : C

One molecule of glucose gives ______ molecules of CO2 in EM-TCA cycle. (A) 6 (B) 3 (C) 1 (D) 2

Description : One molecule of glucose gives ______ molecules of CO2 in EM-TCA cycle. (A) 6 (B) 3 (C) 1 (D) 2

Last Answer : A

A competitive inhibitor of succinic dehydrogenase is (a) α-ketoglutarate (b) malate (c) malonate (d) oxaloacetate.

Description : A competitive inhibitor of succinic dehydrogenase is (a) α-ketoglutarate (b) malate (c) malonate (d) oxaloacetate.

Last Answer : (c) malonate

The ultimate respiratory substrate, yielding maximum number of ATP molecules, is (a) glycogen (b) ketogenic amino acid (c) glucose (d) amylose.

Description : The ultimate respiratory substrate, yielding maximum number of ATP molecules, is (a) glycogen (b) ketogenic amino acid (c) glucose (d) amylose.

Last Answer : (c) glucose

The ratio that most closely approximates the number of net molecules of ATP formed per mole of glucose utilized under aerobic conditions to the net number formed under anaerobic conditions is (A) 4:1 (B) 13:1 (C) 18:1 (D) 24:1

Description : The ratio that most closely approximates the number of net molecules of ATP formed per mole of glucose utilized under aerobic conditions to the net number formed under anaerobic conditions is (A) 4:1 (B) 13:1 (C) 18:1 (D) 24:1

Last Answer : Answer : C

cAMP is so called because it is formed during (A) TCA cycle (B) Urea cycle (C) Rhodopsin cycle (D) It has a cyclic structure

Description : cAMP is so called because it is formed during (A) TCA cycle (B) Urea cycle (C) Rhodopsin cycle (D) It has a cyclic structure

Last Answer : Answer : D

During which stage in the complete oxidation of glucose are the greatest number of ATP molecules formed from ADP? (a) Glycolysis (b) Krebs’ cycle (c) Conversion of pyruvic acid to acetyl CoA (d) Electron transport chain

Description : During which stage in the complete oxidation of glucose are the greatest number of ATP molecules formed from ADP? (a) Glycolysis (b) Krebs’ cycle (c) Conversion of pyruvic acid to acetyl CoA (d) Electron transport chain

Last Answer : (d) Electron transport chain

Where is the most ATP produced in cellular respiration? a. Fermentation b. Electron Transport Chain c. Glycolysis d. Citric Acid Cycle

Description : Where is the most ATP produced in cellular respiration? a. Fermentation b. Electron Transport Chain c. Glycolysis d. Citric Acid Cycle

Last Answer : b. Electron Transport Chain

All the following are produced during the citric acid cycle except: a. CO2. b. 02. c. ATP. d. NADH.

Description : All the following are produced during the citric acid cycle except: a. CO2. b. 02. c. ATP. d. NADH.

Last Answer : a. CO2.

Lactate formed in muscles can be utilised through (A) Rapoport-Luebeling cycle (B) Glucose-alanine cycle (C) Cori’s cycle (D) Citric acid cycle

Description : Lactate formed in muscles can be utilised through (A) Rapoport-Luebeling cycle (B) Glucose-alanine cycle (C) Cori’s cycle (D) Citric acid cycle

Last Answer : C

Select the option which is not correct with respect to enzyme action. (a) Substrate binds with enzyme at its active site. (b) Addition of lot of succinate does not reverse the inhibition of succinic dehydrogenase by malonate. (c) A non-competitive inhibitor binds the enzyme at a site distinct from that which binds the substrate. (d) Malonate is a competitive inhibitor of succinic dehydrogenase.

Description : Select the option which is not correct with respect to enzyme action. (a) Substrate binds with enzyme at its active site. (b) Addition of lot of succinate does not reverse the inhibition ... from that which binds the substrate. (d) Malonate is a competitive inhibitor of succinic dehydrogenase.

Last Answer : (b) Addition of lot of succinate does not reverse the inhibition of succinic dehydrogenase by malonate.

The enzyme phosphoenolpyruvate carboxykinase catalyses the conversion of oxaloacetate to phosphoenolpyruvate requires (A) ATP (B) ADP (C) AMP (D) GTP

Description : The enzyme phosphoenolpyruvate carboxykinase catalyses the conversion of oxaloacetate to phosphoenolpyruvate requires (A) ATP (B) ADP (C) AMP (D) GTP

Last Answer : Answer : D

In presence of the following cofactor, pyruvate carboxylase converts pyruvate to oxaloacetate: (A) ATP, Protein and CO2 (B) CO2 and ATP (C) CO2 (D) Protein

Description : In presence of the following cofactor, pyruvate carboxylase converts pyruvate to oxaloacetate: (A) ATP, Protein and CO2 (B) CO2 and ATP (C) CO2 (D) Protein

Last Answer : A

Which of the following compound is a positive allosteric modifier of the enzyme pyruvate carboxylase? (A) Biotin (B) Acetyl CoA (C) Oxaloacetate (D) ATP

Description : Which of the following compound is a positive allosteric modifier of the enzyme pyruvate carboxylase? (A) Biotin (B) Acetyl CoA (C) Oxaloacetate (D) ATP

Last Answer : A

The reaction catalysed by phosphofructokinase (A) Is activated by high concentrations of ATP and citrate (B) Uses fruitose-1-phosphate as substrate (C) Is the rate-limiting reaction of the glycolytic pathway (D) Is inhibited by fructose 2, 6-bisphosphate

Description : The reaction catalysed by phosphofructokinase (A) Is activated by high concentrations of ATP and citrate (B) Uses fruitose-1-phosphate as substrate (C) Is the rate-limiting reaction of the glycolytic pathway (D) Is inhibited by fructose 2, 6-bisphosphate

Last Answer : C

The most important source of reducing equivalents for FA synthesis on the liver is (A) Glycolysis (B) HMP-Shunt (C) TCA cycle (D) Uronic acid pathway

Description : The most important source of reducing equivalents for FA synthesis on the liver is (A) Glycolysis (B) HMP-Shunt (C) TCA cycle (D) Uronic acid pathway

Last Answer : Answer : B

Before pyruvic acid enters the TCA cycle it must be converted to (A) Acetyl CoA (B) Lactate (C) α-ketoglutarate (D) Citrate

Description : Before pyruvic acid enters the TCA cycle it must be converted to (A) Acetyl CoA (B) Lactate (C) α-ketoglutarate (D) Citrate

Last Answer : A

Our body can get pentoses from (A) Glycolytic pathway (B) Uromic acid pathway (C) TCA cycle (D) HMP shunt

Description : Our body can get pentoses from (A) Glycolytic pathway (B) Uromic acid pathway (C) TCA cycle (D) HMP shunt

Last Answer : D

Pentose production is increased in (A) HMP shunt (B) Uromic acid pathway (C) EM pathway (D) TCA cycle

Description : Pentose production is increased in (A) HMP shunt (B) Uromic acid pathway (C) EM pathway (D) TCA cycle

Last Answer : A

Out of 36 ATP molecules produced per glucose molecule during respiration (a) 2 are produced outside glycolysis and 34 during respiratory chain (b) 2 are produced outside mitochondria and 34 inside mitochondria (c) 2 during glycolysis and 34 during Krebs’ cycle (d) all are formed inside mitochondria

Description : Out of 36 ATP molecules produced per glucose molecule during respiration (a) 2 are produced outside glycolysis and 34 during respiratory chain (b) 2 are produced outside mitochondria and 34 inside ... (c) 2 during glycolysis and 34 during Krebs' cycle (d) all are formed inside mitochondria

Last Answer : (b) 2 are produced outside mitochondria and 34 inside mitochondria

Out of 38 ATP molecules produced per glucose, 32 ATP molecules are formed from NADH/FADH2 in (a) respiratory chain (b) Krebs’ cycle (c) oxidative decarboxylation (d) EMP.

Description : Out of 38 ATP molecules produced per glucose, 32 ATP molecules are formed from NADH/FADH2 in (a) respiratory chain (b) Krebs’ cycle (c) oxidative decarboxylation (d) EMP.

Last Answer : (a) respiratory chain

An example of feedback inhibition is (A) Allosteric inhibition of hexokinase by glucose6-phosphate (B) Cyanide action on cytochrome (C) Sulpha drug on folic acid synthesizer bacteria (D) Reaction between succinic dehydrogenase and succinic acid

Description : An example of feedback inhibition is (A) Allosteric inhibition of hexokinase by glucose6-phosphate (B) Cyanide action on cytochrome (C) Sulpha drug on folic acid synthesizer bacteria (D) Reaction between succinic dehydrogenase and succinic acid

Last Answer : Answer : A