Description : A compound serving a link between citric acid cycle and urea cycle is (A) Malate (B) Citrate (C) Succinate (D) Fumarate
Last Answer : Answer : D
Description : The reaction of Kreb’s cycle which does not require cofactor of vitamin B group is (A) Citrate isocitrate (B) α -Ketoglutarate succinate (C) Malate oxaloacetate (D) Succinate fumarate
Last Answer : Answer : A
Description : Fluoroacetate inhibits the reaction of citric acid cycle: (A) Isocitrate α-Ketoglutarate (B) Fumarate α-Malate (C) Citrate α-cis-aconitate (D) Succinate α-fumarate
Last Answer : Answer : C
Description : All of the following compounds are intermediates of TCA cycle except (A) Maleate (B) Pyruvate (C) Oxaloacetate (D) Fumarate
Last Answer : Answer : B
Description : Mitochondrial membrane is freely preamble to (A) Pyruvate (B) Malate (C) Oxaloacetate (D) Fumarate
Description : Out of 24 mols of ATP formed in TCA cycle, 2 molecules of ATP can be formed at “substrate level” by which of the following reaction ? (A) Citric acid→ Isocitric acid (B) Isocitrate→ Oxaloacetate (C) Succinic acid→ Fumarate (D) Succinylcat→ Succinic acid
Last Answer : D
Description : All of the following intermediates of citric acid cycle can be formed from amino acids except (A) α-Ketoglutarate (B) Fumarate (C) Malate (D) Oxaloacetate
Description : The example of generation of a high energy phosphate at the substrate level in the citric acid cycle is the reaction: (A) Isocitrate α-Ketoglutarate (B) Succinate α-fumarate (C) Malate α-oxaloacetate (D) Succinyl CoA α-Succinate
Description : The substance which may be considered to play a catalytic role in citric acid cycle is (A) Oxaloacetate (B) Isocitrate (C) Malate (D) Fumarate
Description : The carrier of the citric acid cycle is (A) Succinate (B) Fumarate (C) Malate (D) Oxaloacetate
Description : Substrate level phosphorylation in TCA cycle is in step: (A) Isocitrate dehydrogenase (B) Malate dehydrogenase (C) Aconitase (D) Succinate thiokinase
Description : Before pyruvic acid enters the TCA cycle it must be converted to (A) Acetyl CoA (B) Lactate (C) α-ketoglutarate (D) Citrate
Last Answer : A
Description : A carrier molecule in the citric acid cycle is (A) Acetyl-CoA (B) Citrate (C) Oxaloacetate (D) Malate
Description : An enzyme of the citric acid cycle also found outside the mitochondria is (A) Isocitrate dehydrogenase (B) Citrate synthetase (C) α-Ketoglutarate dehydrogenase (D) Malate dehydrogenase
Description : All of the following are intermediates of citric acid cycle except (A) Oxalosuccinate (B) Oxaloacetate (C) Pyruvate (D) Fumarate
Description : All enzymes of TCA cycle are located in the mitochondrial matrix except one which is located in inner mitochondrial membranes in eukaryotes and in cytosol in prokaryotes. This enzyme is (a) isocitrate dehydrogenase (b) malate dehydrogenase (c) succinate dehydrogenase (d) lactate dehydrogenase.
Last Answer : (c) succinate dehydrogenase
Description : In the TCA cycle, at which of the following enzyme-catalyzed steps, incorporation of elements of water into an intermediate of the cycle takes place : (A) Citrate synthase (B) Aconitase (C) Maleate dehydrogenase (D) Succinyl Co-A synthase
Last Answer : (C) Maleate dehydrogenase
Description : cAMP is so called because it is formed during (A) TCA cycle (B) Urea cycle (C) Rhodopsin cycle (D) It has a cyclic structure
Description : Citrulline is an intermediate of (A) TCA cycle (B) Urea cycle (C) Pentose cycle (D) Calvin cycle
Description : The initial step of the citric acid cycle is (A) Conversion of pyruvate to acetyl-CoA (B) Condensation of acetyl-CoA with oxaloacetate (C) Conversion of citrate to isocitrate (D) Formation of α -ketoglutarate catalysed by isocitrate dehydrogenase
Description : The metabolism of protein is integrated with that of carbohydrate and fat through (A) Oxaloacetate (B) Citrate (C) Isocitrate (D) Malate
Description : Coenzymes derived from the vitamin shown below are required by which of the following enzymes? (A) Lactate dehydrogenase (B) Glutamate dehydrogenase (C) Pyruvate dehydrogenase (D) Malate dehydrogenase
Description : Fully activated pyruvate carboxylase depends upon the presence of (A) Malate and Niacin (B) Acetyl CoA and biotin (C) Acetyl CoA and thiamine pyrophosphate (D) Oxaloacetate and biotin
Description : Vitamin B12 deficiency can be diagnosed by urinary excretion of (A) Pyruvate (B) Methylmalonate (C) Malate (D) Lactate
Description : NADPH is produced when this enzyme acts (A) Pyruvate dehydrogenase (B) Malic enzyme (C) Succinate dehydrogenase (D) Malate dehydrogenase
Description : Anion gap of plasma can be due to the presence of all the following except (A) Bicarbonate (B) Lactate (C) Pyruvate (D) Citrate
Description : Formation of acetyl CoA from pyruvate for de novo synthesis of fatty acids requires (A) Pyruvate dehydrogenase complex (B) Citrate synthetase (C) ATP citrate lyase (D) All of these
Description : Phosphofructokinase is allosterically inhibited by (A) Fructose-1, 6-biphosphate (B) Lactate (C) Pyruvate (D) Citrate
Description : Acetyl-CoA is the principal building block of fatty acids. It is produced within the mitochondria and does not diffuse readily into cytosol. The availability of acetyl CoA involves (A) Carnitine acyl transferase (B) Pyruvate dehydrogenase (C) Citrate lyase (D) Thiolase
Description : In gluconeogensis, an allosteric activator required in the synthesis of oxaloacetate from bicarbonate and pyruvate, which is catalysed by the enzyme pyruvate carboxylase is (A) Acetyl CoA (B) Succinate (C) Isocitrate (D) Citrate
Description : Acetyl CoA required for extra mitochondrial fatty acid synthesis is produced by (A) Pyruvate dehydrogenase complex (B) Citrate lyase (C) Thiolase (D) Carnitine-acyl transferase
Description : While citrate is converted to isocitrate in the mitochondria, it is converted to _______ in the cytosol. (A) Acetyl CoA + oxaloacetate (B) Acetyl CoA + malonyl CoA (C) Acetyl CoA + Pyruvate (D) Acetyl CoA + acetoacetyl CoA
Description : How many ATPs are produced in the conversion of phosphoenol pyruvate to citrate? (A) 1 (B) 2 (C) 4 (D) 6
Last Answer : C
Description : An aneplerotic reaction which sustains the availability of oxaloacetate is the carboxylation of (A) Glutamate (B) Pyruvate (C) Citrate (D) Succinate
Last Answer : B
Description : Which of the following metabolite integrates glucose and fatty acid metabolism? (A) Acetyl CoA (B) Pyruvate (C) Citrate (D) Lactate
Description : In TCA cycle, oxalosuccinate is converted to α-ketoglutarate by the enzyme: (A) Fumarase (B) Isocitrate dehydrogenase (C) Aconitase (D) Succinase
Description : The most important source of reducing equivalents for FA synthesis on the liver is (A) Glycolysis (B) HMP-Shunt (C) TCA cycle (D) Uronic acid pathway
Description : Most of the metabolic pathways are either anabolic or catabolic. Which of the following pathways is considered as “amphibolic” in nature? (A) Glycogenesis (B) Glycolytic pathway (C) Lipolysis (D) TCA cycle
Description : One molecule of glucose gives ______ molecules of CO2 in EM-TCA cycle. (A) 6 (B) 3 (C) 1 (D) 2
Description : The number of molecules of ATP produced by the total oxidation of acetyl CoA in TCA cycle is (A) 6 (B) 8 (C) 10 (D) 12
Description : Our body can get pentoses from (A) Glycolytic pathway (B) Uromic acid pathway (C) TCA cycle (D) HMP shunt
Description : Pentose production is increased in (A) HMP shunt (B) Uromic acid pathway (C) EM pathway (D) TCA cycle
Description : Among citric acid cycle enzymes, a flavoprotein is (A) Malate (B) Fumarase (C) Succinate dehrogenase (D) Isocitrate dehrogenase
Description : The rate of citric acid cycle is controlled by the allosteric enzyme: (A) Aconitase (B) Fumarase (C) Fumarase (D) Malate dehydrogenase
Description : An allosteric enzyme responsible for controlling the rate of T.C.A cycle is (A) Malate dehydrogenase (B) Isocitrate dehydrogenase (C) Fumarase (D) Aconitase
Description : Fertiliser having high nitrogen content is – (1) Urea (2) Ammonium sulphate (3) Ammonium nitrate (4) Calcium citrate
Last Answer : (3) Ammonium nitrate Explanation: A growth fertilizer will have a high N content and relatively low P and K content. Ammonium nitrate is the highest Nitrogen fertilizer you can buy, and it is ... formulations of growth fertilizers will contain 5, 6 or even 7 times more Nitrogen than anything else.
Description : Fertiliser having high nitrogen content is : (1) Urea (2) Ammonium sulphate (3) Ammonium nitrate (4) Calcium citrate
Last Answer : Ammonium nitrate
Description : Why is the Krebs cycle called the TCA cycle ?
Last Answer : The first acid produced in the Krebs cycle is citric acid. Since citric acid contains three carboxylic (- COOH) radicals , the Krebs-cycle is called the TCA cycle or tri-carboxylic acid cycle.
Description : TCA cycle starts with the condensation of acetyl group with (A) _____ (B)_____ to yield citric acid.
Last Answer : TCA cycle starts with the condensation of acetyl group with (A) _____ (B)_____ to yield citric acid.