Description : For the activation of long chain fatty acids the enzyme thiokinase requires the cofactor: (A) Mg++ (B) Ca++ (C) Mn++ (D) K+
Last Answer : Answer : B
Description : De novo synthesis of fatty acids requires all of the following except (A) Biotin (B) NADH (C) Panthothenic acid (D) ATP
Last Answer : Answer : D
Description : All the following statements about carnitine are true except (A) It can be synthesised in the human body (B) It can be synthesized from methionine and lysine (C) It is required for transport of short chain fatty acids into mitochondria (D) Its deficiency can occur due to haemodialysis
Last Answer : Answer : C
Description : All of the following statements about thioredoxin reductase are true except: (A) It requires NADH as a coenzyme (B) Its substrates are ADP, GDP, CDP and UDP (C) It is activated by ATP (D) It is inhibited by dADP
Last Answer : Answer : A
Description : Fatty acids are activated to acyl CoA by the enzyme thiokinase: (A) NAD+ (B) NADP+ (C) CoA (D) FAD+
Description : Mitochondrial thiokinase acts on (A) Short chain of fatty acids (B) Medium chain fatty acids (C) Long chain fatty acids (D) All of these
Description : Formation of acetyl CoA from pyruvate for de novo synthesis of fatty acids requires (A) Pyruvate dehydrogenase complex (B) Citrate synthetase (C) ATP citrate lyase (D) All of these
Description : Acetyl-CoA is the principal building block of fatty acids. It is produced within the mitochondria and does not diffuse readily into cytosol. The availability of acetyl CoA involves (A) Carnitine acyl transferase (B) Pyruvate dehydrogenase (C) Citrate lyase (D) Thiolase
Description : Carnitine is required for the transport of (A) Triglycerides out of liver (B) Triglycerides into mitochondria (C) Short chain fatty acids into mitochondria (D) Long chain fatty acids into mitochondria
Description : Long chain fatty acids penetrate the inner mitochondrial membrane (A) Freely (B) As acyl-CoA derivative (C) As carnitine derivative (D) Requiring Na dependent carrier
Description : Calcium is required for the activation of the enzyme: (A) Isocitrate dehydrogenase (B) Fumarase (C) Succinate thiokinase (D) ATPase
Description : β-Oxidation of fatty acids requires all the following coenzymes except (A) CoA (B) FAD (C) NAD (D) NADP
Description : Which of the following regulates lipolysis in adipocytes? (A) Activation of fatty acid synthesis mediated by CAMP (B) Glycerol phosphorylation to prevent futile esterification of fatty acids (C) ... result of hormone stimulated increases in CAMP levels (D) Activation of CAMP production by Insulin
Description : Insulin regulates fatty acid synthesis by (A) Dephosphorylating of acetyl CoA carboxylase (B) Activating phosphorylase (C) Inhibiting malonyl CoA formation (D) Controlling carnitine-Acyl CoA transferase activity
Description : Acetyl CoA required for extra mitochondrial fatty acid synthesis is produced by (A) Pyruvate dehydrogenase complex (B) Citrate lyase (C) Thiolase (D) Carnitine-acyl transferase
Description : Long chain fatty acyl CoA esters are transported across the mitochondrial membrane by (A) cAMP (B) Prostaglandin (C) Carnitine (D) Choline
Description : With the exception of glycine all amino acids found in protein are (A) Isocitrate dehydrogenase (B) Fumarase (C) Succinate thiokinase (D) ATPase
Description : In non shivering thermogenesis (A) Glucose is oxidized to lactate (B) Fatty acids uncouple oxidative phosphorylation (C) Ethanol is formed (D) ATP is burned for heat production
Description : A soluble system for synthesis of fatty acids have been isolated from avian liver, required for the formation of long chain fatty acids by this system is (A) ATP (B) Acetyl CoA (C) NADPH (D) All of these
Description : When unsaturated fatty acids are oxidised, how many ATP is formed?
Last Answer : The energy yield is less by 2 ATP molecules per double bond, when compared to the corresponding chain length saturated fatty acid.
Description : All of the following are allosteric enzymes except (A) Citrate synthetase (B) a-Ketoglutarate dehdrogenase (C) Succinate thiokinase (D) Succinate dehydrogenase
Description : All the following compounds are members of the electron transport chain except (A) Ubiquinone (B) Carnitine (C) NAD (D) FAD
Description : Transaminase activity needs the Coenzyme: (A) ATP (B) B6-PO4 (C) FADT (D) NAD+
Description : Which one is coenzyme? (A) ATP (B) Vitamin B and C (C) CoQ and CoA (D) All of these
Description : In most metabolic pathways, all needed enzymes are arranged together in a multienzyme complex within a (A) Solution of ATP (B) Membrane (C) Quanternary protein (D) Coenzyme
Description : The abnormal isoenzyme need not (A) Be an oxidoreductase (B) Have any coenzyme (C) Require ATP (D) Be localized intracellularly (E) Be a catalyst
Description : Coenzyme for phosphoenolpyruvate carboxykinase is (A) ATP (B) ADP (C) GTP (D) GDP
Description : In conversion of glucose to glucose-6- phsophate, the coenzyme is (A) Mg++ (B) ATP (C) Both (A) and (B) (D) None of these
Description : A coenzyme containing non aromatic hetero ring is (A) ATP (B) NAD (C) FMN (D) Biotin
Description : Acyl-CoA dehydrogenase converts Acyl CoA to α-β unsaturated acyl-CoA in presence of the coenzyme: (A) NAD+ (B) NADP+ (C) ATP (D) FAD
Description : The transaminase activity needs the coenzyme: (A) ATP (B) B6 – PO4 (C) FAD+ (D) NAD+
Description : A coenzyme required for the synthesis of glycine from serine is (A) ATP (B) Pyridoxal phosphate (C) Tetrahydrofolate (D) NAD
Description : All the following statements about acetyl CoA carboxylase are true except (A) It is required for de novo synthesis of fatty acids (B) It is required for mitochondrial elongation of fatty acids ( ... for microsomal elongation of fatty acids (D) Insulin converts its inactive form into its active form
Description : All the following saturated fatty acids are present in buffer except (A) Butyric acid (B) Capryllic acid (C) Caproic acid (D) Capric acid
Description : Oils having more than 50 % polyunsaturated fatty acids include all of the following except (A) Groundnut oil (B) Soyabean oil (C) Sunflower oil (D) Safflower oil
Description : Acetyl CoA formed from pyruvate can be used for the synthesis of all the following except (A) Glucose (B) Fatty acids (C) Cholesterol (D) Steroid hormones
Description : Fluidity of membranes is increased by the following constituent except (A) Polyunsaturated fatty acids (B) Saturated fatty acids (C) Integral proteins (D) Cholesterol
Description : All the following statements about brown adipose tissue are true except (A) It is rich in cytochromes (B) It oxidizes glucose and fatty acids (C) Oxidation and phosphorylation are tightly coupled in it (D) Dinitrophenol has no effect on it
Description : Release of free fatty acids from adipose tissue is increased by all of the following except (A) Glucagon (B) Epinephrine (C) Growth hormone (D) Insulin
Description : All of the following statements about hypoglycin are true except (A) It is a plant toxin (B) It causes hypoglycaemia (C) It inhibits oxidation of short chain fatty acids (D) It inhibits oxidation of long chain fatty acids
Description : Refsum’s disease results from a defect in the following pathway except (A) Alpha-oxidation of fatty acids (B) Beta-oxidation of fatty acids (C) Gamma-oxidation of fatty acids (D) Omega-oxidation of fatty acids
Description : All the following can be oxidized by βoxidation except (A) Palmitic acid (B) Phytanic acid (C) Linoleic acid (D) Fatty acids having an odd number of carbon atoms
Description : All the following are omega-6-fatty acids except (A) Linoleic acid (B) α-Linolenic acid (C) γ-Linolenic acid (D) Arachidonic acid
Description : Egg is rich in all of the following except (A) Cholesterol (B) Saturated fatty acids (C) Ascorbic acid (D) Calcium
Description : Which one of the following tissues can metabolize glucose, fatty acids and ketone bodies for ATP production? a. Liver b. Muscle c. Brain d. R.B.C
Last Answer : Ans: B
Description : Both Acyl carrier protein (ACP) of fatty acid synthetase and coenzyme (CoA) are (A) Contain reactive phosphorylated (B) Contain thymidine (C) Contain phosphopantetheine reactive groups (D) Contain cystine reactive groups
Description : Fatty acid synthesis takes place in the presence of the coenzyme: (A) NAD+ (B) Reduced NAD (C) NADP+ (D) Reduced NADP
Description : Which one of the following enzymes requires a coenzyme derived from the vitamin whose structure is shown below? (A) Enoyl CoA hydratase (B) Phosphofructokinase (C) Glucose-6-phosphatase (D) Glucose-6-phosphate dehydrogenase
Description : Enzymes combine with a ___________at the___________ site to lower the activation energy. a. Substrate; Active b. Product; Noncompetitive c. Product; Active d. Coenzyme; Active
Last Answer : a. Substrate; Active
Description : In citric acid cycle, GDP is phosphorylated by (A) Succinate dehydrogenase (B) Aconitase (C) Succinate thiokinase (D) Fumarse