Description : Glucocorticoids are transported in blood (A) In association with transcortin chiefly (B) In association with albumin to some extent (C) In free form partly (D) All of these
Last Answer : Answer : D
Description : Progesterone is transported in blood by (A) Transcortin (B) Sex hormone binding globulin (C) Albumin (D) Testosterone estrogen binding globulin
Last Answer : Answer : A
Description : Lack of Glucocorticoids and mineral corticoids might be consequence of which of the following defects in the adrenal cortex? (A) Androstenadione deficiency (B) Estrone deficiency (C) 17 α-OH progesterone deficiency (D) C- α-Hydroxylase deficiency
Description : Zona glomerulosa of adrenal cortex synthesises (A) Glucocorticoids (B) Mineralocorticoids (C) Androgens (D) Estrogen and progesterone HORMONE METABOLISM 223
Description : The defect in adrenal cortex responsible for lack of glucocorticoids and mineralcorticoids is (A) Androstenedione deficiency (B) 17 α -OH progesterone deficiency (C) C-21 hydroxylase deficiency (D) Testosterone deficiency HORMONE METABOLISM 209
Last Answer : Answer : C
Description : All the following statements about proopiomelanocortin are true except (A) It is made up of 285 amino acids (B) It is synthesised in pars intermedia and anterior lobe of pituitary gland ... ) It is the precursor of corticotropin like intermediate lobe peptide and endorphins 218 MCQs IN BIOCHEMISTRY
Description : All of the following statements about Tangier disease are true except (A) It is a disorder of HDL metabolism (B) Its inheritance is autosomal recessive (C) Apoproteins A-I and A-II are not synthesised (D) Plasma HDL is increased
Description : All the following statements about carnitine are true except (A) It can be synthesised in the human body (B) It can be synthesized from methionine and lysine (C) It is required for transport of short chain fatty acids into mitochondria (D) Its deficiency can occur due to haemodialysis
Description : All the following statements about angiotensin are true except (A) Its precursor is an α2-globulin (B) Its active form is an octapeptide (C) It is a vasodilator (D) It increases the secretion of aldosterone
Description : A common intermediate in the synthesis of cortisol and aldosterone is (A) Progesterone (B) Testosterone (C) Estradiol (D) None of these
Description : All the following statements about ceruloplasmin are correct except (A) It is a copper-containing protein (B) It possesses oxidase activity (C) It is synthesised in intestinal mucosa (D) Its plasma level is decreased inWilson’s disease
Description : Which of the following hormones can play a significant role in osteoporosis? (a) Aldosterone and prolactin (b) Progesterone and aldosterone (c) Estrogen and parathyroid hormone (d) Parathyroid hormone and prolactin (
Last Answer : (c) Estrogen and parathyroid hormone
Description : Which of the following hormones can play a significant role in osteoporesis ? (1) Aldosterone and Prolactin (2) Progesterone and Aldosterone (3) Estrogen and Parathyroid hormone (4) Parathyroid hormone and Prolactin
Last Answer : (3) Estrogen and Parathyroid hormone
Description : Secretion of glucocorticoida is regulated by all the following except (A) Hypothalamus (B) Anterior pituitary (C) Feedback control by blood glucose (D) Feedback control by glucocorticoids
Description : Glucocorticoids increase the synthesis of all of the following except (A) Glucokinase (B) Glucose-6-phosphatase (C) Fructose-1, 6-biphosphatase (D) Pyruvate carboxylase
Description : Glucocorticoids increase all of the following except (A) Gluconeogenesis (B) Lipolysis in extremities (C) Synthesis of elcosanoida (D) Hepatic glycogenesis
Description : Prothrombin is synthesised in (A) Erythrocytes (B) Reticulo-endothelial cells (C) Liver (D) Kidneys
Description : Apolipoprotein B-100 is synthesised in (A) Adipose tissue (B) Liver (C) Intestine (D) Liver and intestine
Last Answer : Answer : B
Description : All of the following statements about bronzed diabetes are true except (A) It is caused by excessive intake of copper (B) Skin becomes pigmented (C) There is damage to β cells of Islets of Langerhans (D) Liver is damaged
Description : All the following statements about obstructive jaundice are true except (A) Prothrombin time may be prolonged due to impaired absorption of vitamin K (B) Serum alkaline phosphatase may be raised ... systemic circulation due to biliary obstruction (D) There is no defect in conjugation of bilirubin
Description : All of the following statements about generalized gangliosidosis are true except (A) It results from deficiency of GM1-βGangliosidase (B) Breakdown of GM1 ganglioside is impaired (C) GM2 ganglioside accumulates in liver and elsewhere (D) It leads to mental retardation
Description : All the following statements about ketone bodies are true except (A) Their synthesis increases in diabetes mellitus (B) They are synthesized in mitchondria (C) They can deplete the alkali reserve (D) They can be oxidized in the liver
Description : Steroid hormones are synthesised in all of the following except (A) Testes (B) Ovaries (C) Adrenal medulla (D) Adrenal cortex
Description : Testosterone is transported in blood by (A) Transcortin (B) Testosterone binding globulin (C) Testosterone estrogen binding globulin (D) Albumin
Description : When thyroxine binding globulin and thyroxine binding pre-albumin are saturated with thyroxine, the excess hormone is transported by (A) Albumin (B) Gamma globulins (C) Transcortin (D) None of these
Description : A specific cortisol binding protein, transcortin is a (A) Albumin (B) α1-Globulin (C) α2-Globulin (D) β-Globulin
Description : Vitamin B12 is transported in blood by (A) Albumin (B) Transcortin (C) Transcobalamin I (D) Transcobalamin II
Description : Glucocorticoids impair carbohydrate tolerance by: A. Promoting gluconeogenesis in liver B. Depressing glucose uptake into skeletal muscles C. Inhibiting insulin secretion D. Both A and B are correct
Last Answer : D. Both A and B are correct
Description : Placenta secretes all of the following except (A) FSH (B) Progesterone (C) Estrogen (D) Chorionic gonadotropin HORMONE METABOLISM 225
Description : The principal nitrogenous excretory compound in humans is synthesised (a) in kidneys but eliminated mostly through liver (b) in kidneys as well as eliminated by kidneys (c) in liver and also eliminated by the same through bile (d) in the liver, but eliminated mostly through kidneys.
Last Answer : (d) in the liver, but eliminated mostly through kidneys.
Description : Vit. D is synthesised in presence of sunlight in (a) Skin (b) Bone(c) Liver (d) Spleen
Last Answer : (a) Skin
Description : All the following statements about Wilson’s disease are correct except (A) It is a genetic disease (B) The defect involves copper-dependent P-type ATPase (C) Copper is deposited in liver, basal ganglia and around cornea (D) Plasma copper level is increased in it
Description : All the following statements correctly describe ketone bodies except (A) They may result from starvation (B) They are present at high levels in uncontrolled diabetes (C) They include—OH β-butyrate and acetone (D) They are utilized by the liver during long term starvation
Description : With respect to lipoprotein transport and metabolism in the body, the following statements are correct EXCEPT: 1) Arterial walls contain cells with LDL receptors. 2) Cholesterol is required for the ... is assembled in the extracellular space. 5) VLDL transformation to LDL occurs in adipose tissue.
Last Answer : Answers-3 Chylomicrons are formed in the gut from exogenous triacylglycerols and cholesterol. They are released into the lymph and thereby enter the blood.They are not formed in the liver.
Description : True statements about aldosterone include: a. secretion is mainly under the control of adrenocorticotrophic (ACTH) hormone secretion b. increases hepatic gluconeogenesis c. its secretion is stimulated by angiotensin d. in the kidney, mainly acts on the proximal convoluted tubules
Last Answer : its secretion is stimulated by angiotensin
Description : True statements about aldosterone include: a. it increases the amount of Na+-K+ ATPase in the target cells b. it reduces the sodium content of the sweat c. it increases the acidity of urine d. all above
Last Answer : all above
Description : Which ONE of the following is true concerning Antidiuretic hormone(ADH)? 1) Carbamazepine potentiates it's release 2) Ethanol potentiates it's release 3) It circulates in the blood bound to neurohypophysin 4) It is a cyclic octapeptide 5) It is synthesised in the posterior pituitary
Last Answer : Answers-1 ADH is a nonapeptide manufactured in the paraventricular and supra-optic nuclei of the hypothalamus and released from the posterior pituitary. It acts on the collecting ducts improving ... agents such as thiazides and SSRIs may potentiate its release. Ethanol usually inhibits release.
Description : After re leas ing O2 at the tissues, hemoglobin transports (A) CO2 and protons to the lungs (B) O2 to the lungs (C) CO2 and protons to the tissue (D) Nutrients
Description : Hydrocortisone induces the synthesis of the following protein which in turn inhibits the enzyme phospholipase-A2: A. Heat shock protein-90 B. Inhibin C. Transcortin D. Lipocortin
Last Answer : D. Lipocortin
Description : It is unique that the following single antidiabetogenic hormone effectively counter acts the several diabetogenic hormones: (A) Glucagon (B) Glucocorticoids (C) Insulin (D) Growth hormone
Description : In adrenogenital syndrome due to total absence of 21-hydroxylase in adrenal cortex, there is (A) Deficient secretion of glucocorticoids (B) Deficient secretion of mineralcorticoids (C) Excessive secretion of androgens (D) All of these
Description : Excessive secretion of glucocorticoids raises blood glucose by (A) Decreasing glycogenesis (B) Increasing glycogenolysis (C) Increasing gluconeogenesis (D) Inhibiting HMP shunt
Description : The second messenger for glucocorticoids is (A) Cyclic AMP (B) Cyclic GMP (C) Inositol triphosphate (D) No second messenger is required
Description : Hyperglycemic effect of glucocorticoids is due to (A) Inactivation of protein phosphatase (B) Inactivation of fructose 1,6-biphosphatase (C) Stimulation of synthesis of pyruvate carboxylase (D) Stimulation of synthesis of eltroxykinase
Description : ACTH stimulates the secretion of (A) Glucocorticoids (B) Epinephrine (C) Thyroxine (D) Luteinizing hormone
Description : Hepatic glycogenoloysis is increased by (A) Insulin (B) Glucagon (C) Epinephrine (D) Glucocorticoids ENZYMES 163
Description : HMG-CoA reductase activity is increased by administration of the hormone: (A) Insulin (B) Glucagon (C) Epinephrine (D) Glucocorticoids
Description : Prostaglandin synfhesis is increased by activating phospholipases by (A) Mepacrine (B) Angiotensin II (C) Glucocorticoids (D) Indomenthacin
Description : Synthesis of prostaglandins is inhibited by (A) Glucocorticoids (B) Aspirin (C) Indomethacin (D) All of these