Which ONE of the following is true concerning Antidiuretic hormone(ADH)? 1) Carbamazepine potentiates it's release 2) Ethanol potentiates it's release 3) It circulates in the blood bound to neurohypophysin 4) It is a cyclic octapeptide 5) It is synthesised in the posterior pituitary

Which ONE of the following is true concerning Antidiuretic hormone(ADH)? 1) Carbamazepine potentiates it's release 2) Ethanol potentiates it's release 3) It circulates in the blood bound to neurohypophysin 4) It is a cyclic octapeptide 5) It is synthesised in the posterior pituitary
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Answers-1 ADH is a nonapeptide manufactured in the paraventricular and supra-optic nuclei of the hypothalamus and released from the posterior pituitary. It acts on the collecting ducts improving water permeability and hence water retention. Carbamazepine as well as other agents such as thiazides and SSRIs may potentiate its release. Ethanol usually inhibits release.
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