Glucocorticoids impair carbohydrate tolerance by:
A. Promoting gluconeogenesis in liver
B. Depressing glucose uptake into skeletal
muscles
C. Inhibiting insulin secretion
D. Both A and B are correct

1 Answer

Answer :

D. Both A and B are correct

Related questions

Description : Guargum limits post-prandial glycaemia by: A. Inhibiting intestinal brush border α-glucosidases B. Slowing carbohydrate absorption from intestine C. Releasing incretins from the intestine D. Promoting uptake of glucose into skeletal muscles

Last Answer : B. Slowing carbohydrate absorption from intestin

Description : Excessive secretion of glucocorticoids raises blood glucose by (A) Decreasing glycogenesis (B) Increasing glycogenolysis (C) Increasing gluconeogenesis (D) Inhibiting HMP shunt

Last Answer : Answer : C

Description : Diazoxide is an effective hypotensive, but is not used in the long-term treatment of hypertension because: A. It impairs glucose tolerance by inhibiting insulin release B. It inhibits uric acid ... causes marked Na+ and water retention leading to development of tolerance D. All of the above

Last Answer : D. All of the above

Description : Adrenaline raises blood glucose level by the following actions except: A. Inducing hepatic glycogenolysis B. Inhibiting insulin secretion from pancreatic β cells C. Augmenting glucagon secretion from pancreatic α cells D. Inhibiting peripheral glucose utilization

Last Answer : D. Inhibiting peripheral glucose utilization

Description : Adrenaline raises blood glucose level by the following actions except: A. Inducing hepatic glycogenolysis B. Inhibiting insulin secretion from pancreatic β cells C. Augmenting glucagon secretion from pancreatic α cells D. Inhibiting peripheral glucose utilization

Last Answer : D. Inhibiting peripheral glucose utilization

Description : Select the drug which can impair carbohydrate tolerance in prediabetics but prolongs insulin hypoglycaemia: A. Salbutamol B. Propranolol C. Prazosin D. Nifedipine

Last Answer : B. Propranolol

Description : Select the drug which can impair carbohydrate tolerance in prediabetics but prolongs insulin hypoglycaemia: A. Salbutamol B. Propranolol C. Prazosin D. Nifedipine

Last Answer : B. Propranolol

Description : Metformin acts by: A. Releasing insulin from pancreas B. Suppressing gluconeogenesis and glucose output from liver

Last Answer : B. Suppressing gluconeogenesis and glucose output from liver

Description : Which of the following represents the action of insulin? (a) Increases blood glucose level by stimulating glucagon production. (b) Decreases blood glucose levels by forming glycogen. (c) ... promoting cellular uptake of glucose. (d) Increases blood glucose levels by hydrolysis of glycogen.

Last Answer : (b) Decreases blood glucose levels by forming glycogen

Description : The effects of glucocorticoid hormones include: a. increase hepatic glycogen synthesis b. decrease glucose uptake by the adipose tissue c. decrease hepatic gluconeogesis d. increase protein synthesis in the skeletal muscles

Last Answer : . increase hepatic glycogen synthesis

Description : Select the correct statement. (a) Glucocorticoids stimulate gluconeogenesis. (b) Glucagon is associated with hypoglycemia. (c) Insulin acts on pancreatic cells and adipocytes. (d) Insulin is associated with hyperglycemia

Last Answer : (a) Glucocorticoids stimulate gluconeogenesis.

Description : Sulfonylurea hypoglycaemics act by: A. Reducing intestinal absorption of glucose B. Increasing insulin secretion from pancreas C. Reversing down-regulation of insulin receptors D. Both ‘B’ and ‘C’ are correct

Last Answer : D. Both ‘B’ and ‘C’ are correct

Description : A 55-year-old male undergoes a total abdominal colectomy. Which of the following statement(s) is/are true concerning the hormonal response to the surgical procedure? a. Adrenocorticotropic ... in serum insulin and a fall in glucagon accelerate hepatic glucose production and maintain gluconeogenesis

Last Answer : Answer: a, c One of the earliest consequence of a surgical procedure is the rise in levels of circulating cortisol that occur in response to a sudden outpouring of ACTH ... hepatic glucose production, and, with other hormones (epinephrine and glucocorticoids), gluconeogenesis is maintained

Description : Adrenaline raises blood glucose level by the following actions except (a) Inducing hepatic glycogenolysis (b) Inhibiting insulin secretion from pancreatic ß cells (c) Augmenting glucagons secretion from pancreatic a cells (d) Inhibiting peripheral glucose utilization

Last Answer : Ans: D

Description : Gluconeogenesis is decreased by (A) Glucagon (B) Epinephrine (C) Glucocorticoids (D) Insulin

Last Answer : D

Description : Insulin is required for the active uptake of glucose by most of the cells except (A) Muscle cells (B) Renal tubular cells (C) Adipocytes (D) Liver cells

Last Answer : Answer : D

Description : Glucose uptake by liver cells is (A) Energy-consuming (B) A saturable process (C) Insulin-dependent (D) Insulin-independent

Last Answer : D

Description : Sucralfate promotes healing of duodenal ulcer by: A. Enhancing gastric mucus and bicarbonate secretion B. Coating the ulcer and preventing the action of acid-pepsin on ulcer base C. Promoting regeneration of mucosa D. Both ‘A’ and ‘B’ are correct

Last Answer : B. Coating the ulcer and preventing the action of acid-pepsin on ulcer base

Description : Long-term thiazide therapy can cause hyperglycaemia by: A. Reducing insulin release B. Interfering with glucose utilization in tissues C. Increasing sympathetic activity D. Increasing corticosteroid secretion

Last Answer : A. Reducing insulin release

Description : Dantrolene sodium reduces skeletal muscle tone by: A. Reducing acetylcholine release from motor nerve endings B. Suppressing spinal polysynaptic reflexes C. Inhibiting the generation of muscle action potential D. Reducing Ca2+ release from sarcoplasmic reticulum in the muscle fibre

Last Answer : D. Reducing Ca2+ release from sarcoplasmic reticulum in the muscle fibre

Description : Ethanol decreases gluconeogenesis by (A) Inhibiting glucose-6-phosphatase (B) Inhibiting PEP carboxykinase (C) Converting NAD+ into NADH and decreasing the availability of pyruvate (D) Converting NAD+ into NADH and decreasing the availability of lactate

Last Answer : C

Description : Glucose entry into the cells of the following organ/ tissue is highly dependent on the presence of insulin: A. Brain B. Liver C. Adipose tissue D. Kidney tubules

Last Answer : C. Adipose tissue

Description : Action of Insulin does not include the following: A. Facilitation of glucose transport into cells B. Facilitation of glycogen synthesis by liver C. Facilitation of neoglucogenesis by liver D. Inhibition of lipolysis in adipose tissue

Last Answer : . Facilitation of neoglucogenesis by liver

Description : The four sketches (A, B, C and D) given below, represent four different types of animal tissues. Which one of these is correctly identified in the options given, along with its ... Smooth Heart Heart muscle contraction tissue (d) (A) Columnar Nephron Secretion epithelium and absorption

Last Answer : (a) (B) Glandular Intestine Secretion epithelium

Description : The hormonal alterations that follow operation and injury favor accelerated gluconeogenesis. This new glucose is consumed by which of the following tissues? A. Central nervous system. B. Skeletal muscle. C. Bone. D. Kidney. E. Tissue in the healing wound.

Last Answer : Answer: ADE DISCUSSION: Glucose is produced in increased amounts to satisfy the fuel requirements of the healing wound. In addition, nerve tissue and the renal medulla also utilize this substrate. Skeletal muscle primarily utilizes fatty acids, and bone utilizes mineral substrate

Description : Epinephrine increases all of the following except (A) Glycogenolysis in muscles (B) Lipolysis in adipose tissue (C) Gluconeogenesis in muscles (D) Glucagon secretion

Last Answer : Answer : C

Description : Losartan differs from enalapril in the following respect: A. It does not potentiate bradykinin B. It depresses cardiovascular reflexes C. It impairs carbohydrate tolerance D. It does not have fetopathic potential

Last Answer : A. It does not potentiate bradykini

Description : Clinically, the angiotensin antagonists share the following features of angiotensin converting enzyme inhibitors except: A. Antihypertensive efficacy B. Potential to reverse left ventricular hypertrophy ... of effect on carbohydrate tolerance D. Potential to induce cough in susceptible individuals

Last Answer : D. Potential to induce cough in susceptible individuals

Description : Secretion of glucocorticoida is regulated by all the following except (A) Hypothalamus (B) Anterior pituitary (C) Feedback control by blood glucose (D) Feedback control by glucocorticoids

Last Answer : Answer : C

Description : Hypoglycemia depresses insulin secretion and thus increases the rate of (A) Hydrolysis (B) Reduction (C) Gluconeogenesis (D) Respiratory acidosis

Last Answer : Answer : C

Description : Ketosis reflects (A) Increased hepatic glucose liberation (B) Increased fatty acid oxidation (C) Increased carbohydrate utilisation (D) Incresed gluconeogenesis

Last Answer : Answer : B

Description : The metabolic actions of adrenaline include the following except: A. Glycogenolysis in liver and muscle B. Inhibition of neoglucogenesis in liver C. Lipolysis in adipose tissue D. Release of potassium from liver followed by its uptake

Last Answer : B. Inhibition of neoglucogenesis in liver

Description : The metabolic actions of adrenaline include the following except: A. Glycogenolysis in liver and muscle B. Inhibition of neoglucogenesis in liver C. Lipolysis in adipose tissue D. Release of potassium from liver followed by its uptake

Last Answer : B. Inhibition of neoglucogenesis in liver

Description : Neuromuscular blocking drugs do not produce central actions because: A. They do not cross the blood-brain barrier B. Nicotinic receptors are not present in the brain C. They are sequestrated in the periphery by tight binding to the skeletal muscles D. They do not ionise at the brain pH

Last Answer : A. They do not cross the blood-brain barrier

Description : Select the skeletal muscle relaxant that is commonly used for endotracheal intubation despite causing histamine release, K+ efflux from muscles and cardiovascular changes: A. Pipecuroniun B. Succinylcholine C. Pancuronium D. Cisatracurium

Last Answer : B. Succinylcholine

Description : Anthelmintic action of piperazine is due to: A. Interference with ATP generation in the worm B. Blockade of glucose uptake by the worm C. Hyperpolarization of nematode muscle by GABA agonistic action D. Depolarization of nematode muscle by activating nicotinic receptors

Last Answer : C. Hyperpolarization of nematode muscle by GABA agonistic action

Description : The most probable mechanism of action of mebendazole is: A. Depolarization of membrane and spastic paralysis of the worm B. Hyperpolarization of membrane and flaccid paralysis of the worm C. Loss of ... inhibition of glucose uptake in the worm D. Tegument damage and leakage of contents of the worm

Last Answer : C. Loss of intracellular microtubules and inhibition of glucose uptake in the worm

Description : Aspirin prolongs bleeding time by inhibiting the synthesis of: A. Clotting factors in liver B. Prostacyclin in vascular endothelium C. Cyclic AMP in platelets D. Thromboxane A2 in platelets

Last Answer : D. Thromboxane A2 in platelets

Description : Gluconeogenesis does not occur in (A) Brain (B) Kidneys (C) Muscles (D) Liver

Last Answer : Answer : C

Description : Choose the correct statement(s) about inhaled glucocorticoids in chronic obstructive pulmonary disease (COPD): A. They are indicated in COPD only for severe/ advanced cases B. Instituted early they retard the progression of COPD C. Their use predisposes to respiratory infections D. Both 'A' and 'B

Last Answer : A. They are indicated in COPD only for severe/ advanced cases

Description : Deficiency of insulin results in (A) Rapid uptake of sugar (B) Low blood glucose level (C) Decrease urine output (D) Presence of glucose in urine

Last Answer : Answer : D

Description : What is the effect of insulin on glucose uptake of cells?

Last Answer : Insulin facilitates the membrane transport of glucose in most of tissues, especially in muscles and adipose tissue. This is by glucose transporter, GIuT4. But glucose uptake by GlT2 is independent of insulin, it is seen in liver and brain.

Description : Regarding retinal metabolism: a. insulin is essential for the uptake of glucose by the retina b. anaerobic metabolism predominates c. the pigment retinal epithelium stores glycogen and supplies the need of the retina d. the demand of oxygen is met entirely by the central retinal artery

Last Answer : anaerobic metabolism predominates

Description : Insulin: a. is secreted as a pro-insulin b. increases protein synthesis c. is required for glucose uptake in all tissues d. is a steroid hormone

Last Answer : is secreted as a pro-insulin

Description : Name a peptide hormone which acts mainly on hepatocytes, adipocytes and enhances cellular glucose uptake and utilisation. (a) Insulin (b) Glucagon (c) Secretin (d) Gastrin

Last Answer : (a) Insulin

Description : Glucocorticoids increase all of the following except (A) Gluconeogenesis (B) Lipolysis in extremities (C) Synthesis of elcosanoida (D) Hepatic glycogenesis

Last Answer : Answer : C

Description : Which one of the following statements is incorrect? (A) Insulin increases glucose phosphorylation (B) Insulin increases glycolysis (C) Insulin augments HMP shunt (D) Insulin promotes gluconeogenesis

Last Answer : Answer : D

Description : Insulin increases (A) Glycogenesis (B) Gluconeogenesis (C) Lipolysis (D) Blood glucose

Last Answer : Answer : A

Description : Insulin decreases (A) Glycogenesis (B) Glyolysis (C) Gluconeogenesis (D) Tubular reabsorption of glucose

Last Answer : Answer : C

Description : The synthesis of glucose from pyruvate by gluconeogenesis (A) Requires the participation of biotin (B) Occurs exclusively in the cytosol (C) Is inhibited by elevated level of insulin (D) Requires oxidation/reduction of FAD

Last Answer : A