N10-formyl and N5N10-methenyl tetrahydrofolate contributes purine carbon atoms at position (A) 4 and 6 (B) 4 and 5 (C) 5 and 6 (D) 2 and 8

1 Answer

Answer :

Answer :  D

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Description : Which one of the following contributes nitrogen atoms to both purine and pyrimidine rings? (A) Aspartate (B) Carbanoyl phosphate (C) Carbondioxide (D) Tetrahydrofolate

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Description : Which of the following contributes nitrogen atoms to both purine and pyrimidine rings? (A) Aspartate (B) Carbamoyl phosphate (C) CO2 (D) Glutamine

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Description : In purine biosynthesis carbon atoms at 4 and 5 position and N at 7 position are contributed by (A) Glycine (B) Glutamine (C) Alanine (D) Threonine

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Description : In purine biosynthesis ring closure in the molecule formyl glycinamide ribosyl-5- phosphate requires the cofactors: (A) ADP (B) NAD (C) FAD (D) ATP and Mg++

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Description : The first reaction unique to purine nucleotide synthesis is catalysed by (A) PRPP synthetase (B) PRPP glutamyl amido transferase (C) Phosphoribosyl glycinamide synthetase (D) Formyl transferase

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Description : An enzyme which acts as allosteric regulator and sensitive to both phosphate concentration and to the purine nucleotides is (A) PRPP synthetase (B) PRPP glutamyl midotransferase (C) HGPR Tase (D) Formyl transferase

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Description : For de novo synthesis of purine nucleotides, glycine provides (A) One nitrogen atom (B) One nitrogen and one carbon atom (C) Two carbon atoms (D) One nitrogen and two carbon atoms

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Description : Aspartate contributes the following carbon atoms of the pyrimidine nucelus: (A) C2 and C4 (B) C5 and C6 (C) C2, C4 and C6 (D) C4, C5 and C6

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Description : One of the main functions of Vitamin K is cofactor for (A) Carboxylate for the formation of γ carboxyglutamate (B) Methylation of δ-adenosyl methionine (C) Carboxylation of biotin (D) One carbon transfer by tetrahydrofolate

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Description : During breakdown of haem, the methenyl bridge between the following two pyrrole rings is broken: (A) I and II (B) II and III (C) III and IV (D) IV and I

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Description : Neogenesis of methyl group is (A) The availability of methyl group form δ adenosyl methionine (B) The availability of methyl group from betaine (C) Interaction between N5 N10 methylene tetra hydrofolate with a NAD+ dependent reductase (D) Availability of methyl group from methyl B12

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Description : Glycine gives __________ atoms of purine. (A) C2, C3 (B) C4, C5 and N7 (C) C4, C5 and N9 (D) C4, C6 and N7

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