DefinitionDisseminated coccidioidomycosis is a fungal infection that spreads through the bloodstream and involves many organs.Alternative NamesCoccidioidomycosis - systemicCauses, incidence, and risk factorsCoccidioidomycosis is caused by breathing in spores from the fungi Coccidioides immitis or Coccidioides posadasii.These fungi are found in the soil in certain parts of the southwestern U.S., Mexico, and Central and South America.The following increase your risk of disseminated coccidioidomycosis:DiabetesA suppressed immune system (immunosuppression), such as that caused by HIV infection or AIDSPregnancyMedicines that weaken your immune system, including steroids, TNF-inhibitors, and chemotherapy drugsLymphomaSymptomsMost acuteinfections cause no symptoms. Other times, the symptoms range