DefinitionOvarian hypofunction is reduced function of the ovaries (including decreased production of hormones).Alternative NamesPremature ovarian failureCauses, incidence, and risk factorsOvarian hypofunction may be caused by genetic factors such as chromosome abnormalities, or it may occur with certain autoimmune disorders that disrupt normal ovarian function.Chemotherapy and radiation therapy can also cause ovarian hypofunction.SymptomsWomen with ovarian hypofunction may develop symptoms of menopause such as hot flashes, mood swings, night sweats, and vaginal dryness. Ovarian hypofunction may also cause difficulty becoming pregnant.Signs and testsA blood test will be done to check your level of follicle-stimulating hormone, or FSH. FSH levels are higher than normal in women with ovarian