Describe the molecular model of DNA in brief as given by Watson and Crick.  

1 Answer

Answer :

Ans: 1. DNA is double helical structure resembles a twisted ladder.

2. Each strand shows 5'→ 3' polarity and one strand is antiparallel to the other. Every strand has deoxyribonucleotides.

3. Each nucleotide has a Deoxyribose sugar, Phosphate and a nitrogen base. Backbone of the strand is made of alternately arranged Sugar and phosphate with diester bonds between them.

4. The nitrogen bases are Thymine (T) and Cytosine (C) as Pyrimidines and Adenine (A) and Guanine (G) as purines.

5. Thymine of one strand pairs with Adenine of another strand by forming 2 hydrogen bonds between them. Similarly G pairs with C and forms 3 hydrogen bonds.

6. Length is variable but the diameter is 20Ao. Length of each spiral is 34Ao and consists of 10 base pairs. The angle between the successive nucleotides of the same strand is 36o

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