The anticholinesterase action of edrophonium is short lasting because termination of its action depends on: A. Dissociation and diffusion of the drug from the enzyme B. Hydrolysis of the drug by the enzyme C. Synthesis of fresh enzyme molecules D. A combination of the above three processes

The anticholinesterase action of edrophonium is short
lasting because termination of its action depends on:
A. Dissociation and diffusion of the drug from the
enzyme
B. Hydrolysis of the drug by the enzyme
C. Synthesis of fresh enzyme molecules
D. A combination of the above three processes
by

1 Answer

Answer :

A. Dissociation and diffusion of the drug from the
enzyme
by

Related questions

The anticholinesterase action of edrophonium is short lasting because termination of its action depends on: A. Dissociation and diffusion of the drug from the enzyme B. Hydrolysis of the drug by the enzyme C. Synthesis of fresh enzyme molecules D. A combination of the above three processes

Description : The anticholinesterase action of edrophonium is short lasting because termination of its action depends on: A. Dissociation and diffusion of the drug from the enzyme B. Hydrolysis of the drug by the enzyme C. Synthesis of fresh enzyme molecules D. A combination of the above three processes

Last Answer : A. Dissociation and diffusion of the drug from the enzyme

Reactivation of cholinesterase enzyme occurs on hydrolysis of the inhibitor by the same enzyme molecule in case of the following anticholinesterase: A. Edrophonium B. Neostigmine C. Dyflos D. Tacrine

Description : Reactivation of cholinesterase enzyme occurs on hydrolysis of the inhibitor by the same enzyme molecule in case of the following anticholinesterase: A. Edrophonium B. Neostigmine C. Dyflos D. Tacrine

Last Answer : B. Neostigmine

Reactivation of cholinesterase enzyme occurs on hydrolysis of the inhibitor by the same enzyme molecule in case of the following anticholinesterase: A. Edrophonium B. Neostigmine C. Dyflos D. Tacrine

Description : Reactivation of cholinesterase enzyme occurs on hydrolysis of the inhibitor by the same enzyme molecule in case of the following anticholinesterase: A. Edrophonium B. Neostigmine C. Dyflos D. Tacrine

Last Answer : B. Neostigmine

Edrophonium is more suitable for differentiating myasthenic crisis from cholinergic crisis because of its: A. Shorter duration of action B. Longer duration of action C. Direct action on muscle end-plate D. Selective inhibition of true cholinesterase

Description : Edrophonium is more suitable for differentiating myasthenic crisis from cholinergic crisis because of its: A. Shorter duration of action B. Longer duration of action C. Direct action on muscle end-plate D. Selective inhibition of true cholinesterase

Last Answer : A. Shorter duration of action

The following inhibitor binds only to the ani-onic site of the cholinesterase enzyme: A. Neostigmine B. Physostigmine C. Edrophonium D. Dyflos

Description : The following inhibitor binds only to the ani-onic site of the cholinesterase enzyme: A. Neostigmine B. Physostigmine C. Edrophonium D. Dyflos

Last Answer : C. Edrophonium

The primary reason for preferring phentolamine as the α adrenergic blocker for performing diagnostic test for pheochromocytoma is: A. It produces rapid and short lasting α-adrenergic blockade B. It equally blocks α1 and α2 adrenoceptors C. It is the most potent α blocker D. It has no additional β adrenergic blocking property

Description : The primary reason for preferring phentolamine as the α adrenergic blocker for performing diagnostic test for pheochromocytoma is: A. It produces rapid and short lasting α-adrenergic blockade B. It equally ... It is the most potent α blocker D. It has no additional β adrenergic blocking property

Last Answer : A. It produces rapid and short lasting α-adrenergic blockade

The primary reason for preferring phentolamine as the α adrenergic blocker for performing diagnostic test for pheochromocytoma is: A. It produces rapid and short lasting α-adrenergic blockade B. It equally blocks α1 and α2 adrenoceptors C. It is the most potent α blocker D. It has no additional β adrenergic blocking property

Description : The primary reason for preferring phentolamine as the α adrenergic blocker for performing diagnostic test for pheochromocytoma is: A. It produces rapid and short lasting α-adrenergic blockade B. It equally ... It is the most potent α blocker D. It has no additional β adrenergic blocking property

Last Answer : A. It produces rapid and short lasting α-adrenergic blockade

A suspected case of poisoning has been brought to the casualty with weakness, fainting, involuntary passage of urine and stools, profuse sweating, salivation, watering from nose and eyes. His pulse is 120/min, low volume, BP 90/60 mm Hg, respiration shallow, pupil constricted, muscles flabby with occasional fasciculations. Which is the most likely type of poisoning: A. Belladonna B. Barbiturate C. Anticholinesterase D. Dicophane (DDT

Description : A suspected case of poisoning has been brought to the casualty with weakness, fainting, involuntary passage of urine and stools, profuse sweating, salivation, watering from nose and eyes. His pulse ... likely type of poisoning: A. Belladonna B. Barbiturate C. Anticholinesterase D. Dicophane (DDT

Last Answer : C. Anticholinesterase

A suspected case of poisoning has been brought to the casualty with weakness, fainting, involuntary passage of urine and stools, profuse sweating, salivation, watering from nose and eyes. His pulse is 120/min, low volume, BP 90/60 mm Hg, respiration shallow, pupil constricted, muscles flabby with occasional fasciculations. Which is the most likely type of poisoning: A. Belladonna B. Barbiturate C. Anticholinesterase D. Dicophane (DDT)

Description : A suspected case of poisoning has been brought to the casualty with weakness, fainting, involuntary passage of urine and stools, profuse sweating, salivation, watering from nose and eyes. His pulse ... likely type of poisoning: A. Belladonna B. Barbiturate C. Anticholinesterase D. Dicophane (DDT)

Last Answer : C. Anticholinesterase

The mechanism by which neostigmine improves contraction of myasthenic muscle involves: A. Repetitive binding of the acetylcholine molecules to the same receptors at the muscle endplate B. Diffusion of acetylcholine released from motor nerve endings to a wider area activating neighbouring receptors C. Activation of motor end-plate receptors by neostigmine molecules themselves D. All of the above

Description : The mechanism by which neostigmine improves contraction of myasthenic muscle involves: A. Repetitive binding of the acetylcholine molecules to the same receptors at the muscle endplate B. Diffusion of ... Activation of motor end-plate receptors by neostigmine molecules themselves D. All of the above

Last Answer : D. All of the above

The enzyme amino acyl tRNA synthetase is involved in (A) Dissociation of discharged tRNA from 80S ribosome (B) Charging of tRNA with specific amino acids (C) Termination of protein synthesis (D) Nucleophilic attack on esterified carboxyl group of peptidyl tRNA

Description : The enzyme amino acyl tRNA synthetase is involved in (A) Dissociation of discharged tRNA from 80S ribosome (B) Charging of tRNA with specific amino acids (C) Termination of protein synthesis (D) Nucleophilic attack on esterified carboxyl group of peptidyl tRNA

Last Answer : Answer : B

The rate limiting enzyme in the synthesis of catecholamines is: A. Tyrosine hydroxylase B. Dopa decarboxylase C. Dopamine β-hydroxylase D. Noradrenaline N-methyl transferase

Description : The rate limiting enzyme in the synthesis of catecholamines is: A. Tyrosine hydroxylase B. Dopa decarboxylase C. Dopamine β-hydroxylase D. Noradrenaline N-methyl transferase

Last Answer : A. Tyrosine hydroxylase

The rate limiting enzyme in the synthesis of catecholamines is: A. Tyrosine hydroxylase B. Dopa decarboxylase C. Dopamine β-hydroxylase D. Noradrenaline N-methyl transferase

Description : The rate limiting enzyme in the synthesis of catecholamines is: A. Tyrosine hydroxylase B. Dopa decarboxylase C. Dopamine β-hydroxylase D. Noradrenaline N-methyl transferase

Last Answer : A. Tyrosine hydroxylase

Choose the drug which is used as a short-term inotropic in severe congestive heart failure and has selective adrenergic β1 agonistic activity but no dopaminergic agonistic activity: A. Dopamine B. Dobutamine C. Amrinone D. Salmeterol

Description : Choose the drug which is used as a short-term inotropic in severe congestive heart failure and has selective adrenergic β1 agonistic activity but no dopaminergic agonistic activity: A. Dopamine B. Dobutamine C. Amrinone D. Salmeterol

Last Answer : B. Dobutamine

Choose the drug which is used as a short-term inotropic in severe congestive heart failure and has selective adrenergic β 1 agonistic activity but no dopaminergic agonistic activity: A. Dopamine B. Dobutamine C. Amrinone D. Salmeterol

Description : Choose the drug which is used as a short-term inotropic in severe congestive heart failure and has selective adrenergic β 1 agonistic activity but no dopaminergic agonistic activity: A. Dopamine B. Dobutamine C. Amrinone D. Salmeterol

Last Answer : B. Dobutamine

Neostigmine is beneficial in cobra envenomation because: A. It binds to and inactivates cobra toxin B. It reverses coma due to cobra toxin C. It counteracts the cardio-depressant action of cobra toxin D. It antagonizes the paralysing action of cobra toxin

Description : Neostigmine is beneficial in cobra envenomation because: A. It binds to and inactivates cobra toxin B. It reverses coma due to cobra toxin C. It counteracts the cardio-depressant action of cobra toxin D. It antagonizes the paralysing action of cobra toxin

Last Answer : D. It antagonizes the paralysing action of cobra toxin

Neostigmine is preferred over physostigmine for treating myasthenia gravis because: A. It is better absorbed orally B. It has longer duration of action C. It has additional direct agonistic action on nicotinic receptors at the muscle end plate D. It penetrates blood-brain barrier

Description : Neostigmine is preferred over physostigmine for treating myasthenia gravis because: A. It is better absorbed orally B. It has longer duration of action C. It has additional direct agonistic action on nicotinic receptors at the muscle end plate D. It penetrates blood-brain barrier

Last Answer : C. It has additional direct agonistic action on nicotinic receptors at the muscle end plate

Neostigmine is beneficial in cobra envenomation because: A. It binds to and inactivates cobra toxin B. It reverses coma due to cobra toxin C. It counteracts the cardio-depressant action of cobra toxin D. It antagonizes the paralysing action of cobra toxin

Description : Neostigmine is beneficial in cobra envenomation because: A. It binds to and inactivates cobra toxin B. It reverses coma due to cobra toxin C. It counteracts the cardio-depressant action of cobra toxin D. It antagonizes the paralysing action of cobra toxin

Last Answer : D. It antagonizes the paralysing action of cobra toxin

The most efficacious inhibitor of catecholamine synthesis in the body is: A. α-methyl-p-tyrosine B. α-methyldopa C. α-methyl-norepinephrine D. Entacapone

Description : The most efficacious inhibitor of catecholamine synthesis in the body is: A. α-methyl-p-tyrosine B. α-methyldopa C. α-methyl-norepinephrine D. Entacapone

Last Answer : A. α-methyl-p-tyrosine

Sildenafil is contraindicated in patients taking the following class of drugs: A. α-adrenergic blockers B. β-adrenergic blockers C. Organic nitrates D. Angiotensin converting enzyme inhibitors

Description : Sildenafil is contraindicated in patients taking the following class of drugs: A. α-adrenergic blockers B. β-adrenergic blockers C. Organic nitrates D. Angiotensin converting enzyme inhibitors

Last Answer : C. Organic nitrates

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Description : Sildenafil is contraindicated in patients taking the following class of drugs: A. α-adrenergic blockers B. β-adrenergic blockers C. Organic nitrates D. Angiotensin converting enzyme inhibitors

Last Answer : C. Organic nitrates

Select the drug which can impair carbohydrate tolerance in prediabetics but prolongs insulin hypoglycaemia: A. Salbutamol B. Propranolol C. Prazosin D. Nifedipine

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Last Answer : B. Propranolol

Select the drug which is administered orally for erectile dysfunction in men: A. Yohimbine B. Papaverine C. Alprostadil D. Sildenafil

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Last Answer : D. Sildenafil

The drug which produces vasoconstriction despite being an α adrenergic blocker is: A. Phenoxybenzamine B. Ergotamine C. Dihydroergotoxine D. Tolazoline

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Last Answer : B. Ergotamine

Choose the correct statement about sibutramine: A. It is an anorectic drug used to assist weight reduction B. It is an atypical antidepressant C. It is a 5-HT1D receptor antagonist D. Both A and C are correct

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Last Answer : A. It is an anorectic drug used to assist weight reduction

Which is the most important drug in the treatment of organophosphate poisoning: A. Atropine sulfate B. Pralidoxime C. Diazepam D. Adrenaline

Description : Which is the most important drug in the treatment of organophosphate poisoning: A. Atropine sulfate B. Pralidoxime C. Diazepam D. Adrenaline

Last Answer : A. Atropine sulfate

To be used as a topically applied ocular beta blocker a drug should have the following properties except: A. Strong local anaesthetic activity B. High lipophilicity C. High ocular capture D. Low systemic activity

Description : To be used as a topically applied ocular beta blocker a drug should have the following properties except: A. Strong local anaesthetic activity B. High lipophilicity C. High ocular capture D. Low systemic activity

Last Answer : A. Strong local anaesthetic activity

Select the drug that suppresses essential tremor, but not parkinsonian tremor: A. Procyclidine B. Propranolol C. Promethazine D. Prochlorperazine

Description : Select the drug that suppresses essential tremor, but not parkinsonian tremor: A. Procyclidine B. Propranolol C. Promethazine D. Prochlorperazine

Last Answer : B. More potent α adrenergic blocking than β blocking activity

Select the drug which can impair carbohydrate tolerance in prediabetics but prolongs insulin hypoglycaemia: A. Salbutamol B. Propranolol C. Prazosin D. Nifedipine

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Last Answer : B. Propranolol

Select the drug which is administered orally for erectile dysfunction in men: A. Yohimbine B. Papaverine C. Alprostadil D. Sildenafil

Description : Select the drug which is administered orally for erectile dysfunction in men: A. Yohimbine B. Papaverine C. Alprostadil D. Sildenafil

Last Answer : D. Sildenafil

Which is the most important drug in the treatment of organophosphate poisoning: A. Atropine sulfate B. Pralidoxime C. Diazepam D. Adrenaline

Description : Which is the most important drug in the treatment of organophosphate poisoning: A. Atropine sulfate B. Pralidoxime C. Diazepam D. Adrenaline

Last Answer : A. Atropine sulfate

The following is true of fenfluramine except: A. It lacks CNS stimulant action B. Its use has been associated with cardiac abnormalities and pulmonary hypertension C. It causes weight loss independent of reduced food intake D. It enhances serotonergic transmission in the brain

Description : The following is true of fenfluramine except: A. It lacks CNS stimulant action B. Its use has been associated with cardiac abnormalities and pulmonary hypertension C. It causes weight loss independent of reduced food intake D. It enhances serotonergic transmission in the brain

Last Answer : C. It causes weight loss independent of reduced food intake

The pH of an amino acid depends (A) Optical rotation (B) Dissociation constant (C) Diffusion coefficient(D) Chain length

Description : The pH of an amino acid depends (A) Optical rotation (B) Dissociation constant (C) Diffusion coefficient(D) Chain length

Last Answer : Answer : B

Esmolol has the following features except: A. Rapidly developing, shortlasting β adrenergic blockade B. Cardioselectivity of action C. Intrinsic sympathomimetic activity D. Suitability for intraoperative use

Description : Esmolol has the following features except: A. Rapidly developing, shortlasting β adrenergic blockade B. Cardioselectivity of action C. Intrinsic sympathomimetic activity D. Suitability for intraoperative use

Last Answer : C. Intrinsic sympathomimetic activity

Ephedrine is similar to adrenaline in the following feature: A. Potency B. Inability to penetrate blood-brain barrier C. Duration of action D. Producing both α and β adrenergic effects

Description : Ephedrine is similar to adrenaline in the following feature: A. Potency B. Inability to penetrate blood-brain barrier C. Duration of action D. Producing both α and β adrenergic effects

Last Answer : D. Producing both α and β adrenergic effects

The following action of adrenaline is mediated by both α and β receptors producing the same directional effect: A. Cardiac stimulation B. Intestinal relaxation C. Dilatation of pupil D. Bronchodilatation

Description : The following action of adrenaline is mediated by both α and β receptors producing the same directional effect: A. Cardiac stimulation B. Intestinal relaxation C. Dilatation of pupil D. Bronchodilatation

Last Answer : B. Intestinal relaxation

The following sympathomimetic amine has agonistic action on α1 + α2 + β1 + β3 adrenoceptors, but not on β2 receptors: A. Adrenaline B. Noradrenaline C. Isoprenaline D. Phenylephrine

Description : The following sympathomimetic amine has agonistic action on α1 + α2 + β1 + β3 adrenoceptors, but not on β2 receptors: A. Adrenaline B. Noradrenaline C. Isoprenaline D. Phenylephrine

Last Answer : B. Noradrenaline

The principal process which terminates the action of noradrenaline released from adrenergic nerve ending is: A. Degradation by MAO B. Methylation by COMT C. Axonal uptake D. Extraneuronal uptake

Description : The principal process which terminates the action of noradrenaline released from adrenergic nerve ending is: A. Degradation by MAO B. Methylation by COMT C. Axonal uptake D. Extraneuronal uptake

Last Answer : C. Axonal uptake

Which of the following mydriatics has the fastest and briefest action: A. Atropine B. Homatropine C. Tropicamide D. Cyclopentolate

Description : Which of the following mydriatics has the fastest and briefest action: A. Atropine B. Homatropine C. Tropicamide D. Cyclopentolate

Last Answer : C. Tropicamide

Agonistic action on which of the following adrenergic receptors located on ciliary epithelial cells reduces aqueous secretion: A. β1 receptor B. β2 receptor C. α1 receptor D. α2 receptor

Description : Agonistic action on which of the following adrenergic receptors located on ciliary epithelial cells reduces aqueous secretion: A. β1 receptor B. β2 receptor C. α1 receptor D. α2 receptor

Last Answer : D. α2 receptor

Beta adrenergic blockers lower intraocular tension by: A. Down regulating adenylyl cyclase in ciliary body through reduced activation of β2 adrenoceptors B. Constricting ciliary blood vessels C. Blocking adrenergic action on trabecular meshwork D. Reducing aqueous formation unrelated to beta adrenoceptor mediation

Description : Beta adrenergic blockers lower intraocular tension by: A. Down regulating adenylyl cyclase in ciliary body through reduced activation of β2 adrenoceptors B. Constricting ciliary blood vessels ... action on trabecular meshwork D. Reducing aqueous formation unrelated to beta adrenoceptor mediation

Last Answer : A. Down regulating adenylyl cyclase in ciliary body through reduced activation of β2 adrenoceptors

Pyridostigmine differs from neostigmine in that: A. It is more potent orally B. It is longer acting C. It produces less muscarinic side effects D. It does not have any direct action on NM receptors

Description : Pyridostigmine differs from neostigmine in that: A. It is more potent orally B. It is longer acting C. It produces less muscarinic side effects D. It does not have any direct action on NM receptors

Last Answer : B. It is longer acting

The cotransmitter may serve the following function/ functions: A. Regulate the release of the primary transmitter from the nerve ending B. Alter postjunctional action of the primary transmitter C. Itself act as an alternative transmitter D. All of the above

Description : The cotransmitter may serve the following function/ functions: A. Regulate the release of the primary transmitter from the nerve ending B. Alter postjunctional action of the primary transmitter C. Itself act as an alternative transmitter D. All of the above

Last Answer : D. All of the above

Tetrodotoxin blocks nerve impulse/junctional transmission by: A. Anticholinergic action B. Depleting acetylcholine C. Blocking Na+ channels D. Blocking Ca2+ channels

Description : Tetrodotoxin blocks nerve impulse/junctional transmission by: A. Anticholinergic action B. Depleting acetylcholine C. Blocking Na+ channels D. Blocking Ca2+ channels

Last Answer : C. Blocking Na+ channels

Esmolol has the following features except: A. Rapidly developing, shortlasting β adrenergic blockade B. Cardioselectivity of action C. Intrinsic sympathomimetic activity D. Suitability for intraoperative use

Description : Esmolol has the following features except: A. Rapidly developing, shortlasting β adrenergic blockade B. Cardioselectivity of action C. Intrinsic sympathomimetic activity D. Suitability for intraoperative use

Last Answer : C. Intrinsic sympathomimetic activity

Ephedrine is similar to adrenaline in the following feature: A. Potency B. Inability to penetrate blood-brain barrier C. Duration of action D. Producing both α and β adrenergic effects

Description : Ephedrine is similar to adrenaline in the following feature: A. Potency B. Inability to penetrate blood-brain barrier C. Duration of action D. Producing both α and β adrenergic effects

Last Answer : D. Producing both α and β adrenergic effects

The following action of adrenaline is not mediated by β receptors: A. Dilatation of blood vessels B. Dilatation of pupil C. Bronchodilation D. Renin release from kidney

Description : The following action of adrenaline is not mediated by β receptors: A. Dilatation of blood vessels B. Dilatation of pupil C. Bronchodilation D. Renin release from kidney

Last Answer : B. Dilatation of pupil

The following action of adrenaline is mediated by both α and β receptors producing the same directional effect: A. Cardiac stimulation B. Intestinal relaxation C. Dilatation of pupil D. Bronchodilatation

Description : The following action of adrenaline is mediated by both α and β receptors producing the same directional effect: A. Cardiac stimulation B. Intestinal relaxation C. Dilatation of pupil D. Bronchodilatation

Last Answer : B. Intestinal relaxation

The following sympathomimetic amine has agonistic action on α 1 + α 2 + β 1 + β 3 adrenoceptors, but not on β 2 receptors: A. Adrenaline B. Noradrenaline C. Isoprenaline D. Phenylephrine

Description : The following sympathomimetic amine has agonistic action on α 1 + α 2 + β 1 + β 3 adrenoceptors, but not on β 2 receptors: A. Adrenaline B. Noradrenaline C. Isoprenaline D. Phenylephrine

Last Answer : B. Noradrenaline

The cotransmitter may serve the following function/ functions: A. Regulate the release of the primary transmitter from the nerve ending B. Alter postjunctional action of the primary transmitter C. Itself act as an alternative transmitter D. All of the above

Description : The cotransmitter may serve the following function/ functions: A. Regulate the release of the primary transmitter from the nerve ending B. Alter postjunctional action of the primary transmitter C. Itself act as an alternative transmitter D. All of the above

Last Answer : D. All of the above