The genetic defect–adenosine deaminase (ADA)
deficiency may be cured permanently by
(a) administering adenosine deaminase activators
(b) introducing bone marrow cells producing ADA
into cells at early embryonic stages
(c) enzyme replacement therapy
(d) periodic infusion of genetically engineered
lymphocytes having functional ADA cDNA

1 Answer

Answer :

(b) introducing bone marrow cells producing ADA
into cells at early embryonic stages

Related questions

Description : Which kind of therapy was given in 1990 to a four year old girl with adenosine deaminase (ADA) deficiency?

Last Answer : Which kind of therapy was given in 1990 to a four year old girl with adenosine deaminase (ADA ... B. radiation therapy C. gene therapy D. chemotherapy

Description : Which kind of therapy was given in 1990 to a four- year-old girl with adenosine deaminase (ADA) deficiency? (a) Gene therapy (b) Chemotherapy (c) Immunotherapy (d) Radiation therapy

Last Answer : (a) Gene therapy

Description : Trials for gene therapy in human beings were first carried out, with considerable success, in a genetic disease called (A) Cystic fibrosis (B) Thalassemia (C) Adenosine deaminase deficiency (D) Lesch-Nyhan syndrome

Last Answer : Answer : C

Description : What is Adenosine deaminase (ADA) deficiency? -Biology

Last Answer : answer:

Description : The first clinical gene therapy was given for treating (a) diabetes mellitus (b) chicken pox (c) rheumatoid arthritis (d) adenosine deaminase deficiency.

Last Answer : (d) adenosine deaminase deficiency.

Description : Match the following columns and select the correct option. Column-I Column-II (A) Bt cotton (i) Gene therapy (B) Adenosine (ii) Cellular defence deaminase deficiency (C) RNAi (iii) Detection of HIV infection (D) PCR (iv) Bacillus ... (i) (iv) (c) (ii) (iii) (iv) (i) (d) (i) (ii) (iii) (iv)

Last Answer : (a) (iv) (i) (ii) (iii)

Description : Inherited deficiency of adenosine deaminase causes (A) Hyperuricaemia and gout (B) Mental retardation (C) Immunodeficiency (D) Dwarfism

Last Answer : Answer : C

Description : Enzymic deficiency in β-aminoisobutyric aciduria is (A) Adenosine deaminase (B) Xanthine oxidase (C) Orotidylate decarboxylase (D) Transaminase

Last Answer : Answer : D

Description : An autosomal recessive disorder, xanthinuria is due to deficiency of the enzymes: (A) Adenosine deaminase (B) Xanthine oxidase (C) HGPRTase (D) Transaminase

Last Answer : Answer : B

Description : The enzyme common to catabolism of all the purines is (A) Adenosine deaminase (B) Purine nucleoside phosphorylase (C) Guanase (D) None of these

Last Answer : Answer : B

Description : Lesch-Nyhan syndrome, the sex linked recessive disorder is due to the lack of the enzyme: (A) Hypoxanthine-guanine phosphoribosyl transferse (B) Xanthine oxidase (C) Adenine phosphoribosyl transferase (D) Adenosine deaminase

Last Answer : Answer : A

Description : Cells formed in bone marrow include (a) RBCs (b) RBCs and leucocytes (c) leucocytes (d) lymphocytes

Last Answer : b) RBCs and leucocytes

Description : Which of the following statements is not correct? (a) In man insulin is synthesised as a proinsulin. (b) The proinsulin has an extra peptide called C-peptide. (c) The functional insulin has A and B chains linked together by hydrogen bonds. (d) Genetically engineered insulin is produced in E.Coli.

Last Answer : (c) The functional insulin has A and B chains linked together by hydrogen bonds.

Description : Which of the following is true? Hypochromic anaemia is not due to iron deficiency except (A) Serum ‘Fe’ is high (B) Normal/low transferrin (C) Stainable iron in bone marrow (D) Iron therapy is affective

Last Answer : Answer : D

Description : In India, the organisation responsible for assessing the safety of introducing genetically modified organisms for public use is (a) Indian Council of Medical Research (ICMR) (b) Council for ... Research Committee on Genetic Manipulation (RCGM) (d) Genetic Engineering Appraisal Committee (GEAC).

Last Answer : (d) Genetic Engineering Appraisal Committee (GEAC).

Description : In India, the organisation responsible for assessing the safety of introducing genetically modified organisms for public use is (1) Indian Council of Medical Research (ICMR) (2) Council for ... 3) Research Committee on Genetic Manipulation (RCGM) (4) Genetic Engineering Appraisal Committee (GEAC)

Last Answer : (4) Genetic Engineering Appraisal Committee (GEAC)

Description : The following are true about platelets: a. they are formed in the bone marrow from megakaryocytes. b. their life span in circulation is about 30 days c. in a normal person, 20% of the platelets are found in the spleen. d. they contain adenosine diphophate and serotonin.

Last Answer : they contain adenosine diphophate and serotonin.

Description : 7.Both B & T lymphocytes are produced in the bone marrow; however, only the T lymphocytes travel to the ______ and mature there. 1. Spleen 2. Thymus 3. Pituitary gland 4. Adrenal gland

Last Answer : Ans: Thymus

Description : 1. Both B & T lymphocytes are produced in the bone marrow; however, only the T lymphocytes travel to the ______ and mature there. a. Spleen b. Thymus c. Pituitary gland d. Adrenal gland

Last Answer : b. Thymus

Description : Palliation refers to a) relief of symptoms associated with cancer. Palliation is the goal for care in terminal cancer patients. b) hair loss. Alopecia is the term that refers to hair loss. c) ... the lowest point of white blood cell depression after therapy that has toxic effects on the bone marrow.

Last Answer : a) relief of symptoms associated with cancer. Palliation is the goal for care in terminal cancer patients.

Description : Mammals other than higher primates do not suffer from gout because they (A) Lack xanthine oxidase (B) Lack adenosine deaminase (C) Lack purine nucleoside phosphorylase (D) Possess uricase

Last Answer : Answer : D

Description : What is the histopathology of the pathogenesis of the plaque following 21 days of plaque accumulation: A. Primarily infiltrate of plasma cells B. Primarily infiltrate of lymphocytes C. Infiltrate of plasma cells and early bone involvement D. Infiltrate of neutrophils

Last Answer : C. Infiltrate of plasma cells and early bone involvement

Description : In our society women are blamed for producing female children. Choose the correct answer for the sex-determination in humans. (a) Due to some defect like aspermia in man. (b) Due to the genetic make up of the ... . (c) Due to the genetic make up of the egg. (d) Due to some defect in the women.

Last Answer : (b) Due to the genetic make up of the particular sperm which fertilises the egg.

Description : Consider the following methods by which gene therapy can be performed: 1. By introducing a new gene into the body 2. By the use of stem cells 3. By delivery of genes using gold nanoparticles The correct methods could be: (a) 1 and 2 only (b) 1 and 3 only (c) 2 and 3 only (d) 1, 2 and 3 only

Last Answer : Ans:(a)

Description : Which of the following is commonly used as a vector for introducing a DNA fragment in human lymphocytes? (a) Retrovirus (b) Ti plasmid (c) λ phage (d) pBR322

Last Answer : (a) Retrovirus

Description : Which of the following is commonly used as a vector for introducing a DNA fragment in human lymphocytes ? (1) Retrovirus (2) Ti plasmid (3)  phage (4) pBR 322

Last Answer : (1) Retrovirus

Description : Would it be immoral to enslave someone, that was genetically engineered to want to be a slave?

Last Answer : Creating a genetically engineered underclass would be immoral.

Description : Could Republicans be androids, cyborgs, or genetically engineered humans?

Last Answer : D. They are selfish, greedy, hypocritical bags of shit.

Description : Are Replicants androids, cyborgs, or genetically engineered humans?

Last Answer : They are not humans, they are not grown, they are manufactured. They were designed to be used as slaves, so it didn’t “become legal”; it was never illegal in the first place. But that is why they were to be used on distant planets, not on earth.

Description : Would you eat genetically modified (or engineered) salmon?

Last Answer : Although, I don't think the fish would harm me, I am against what it does to the fish. I would try to avoid it like I avoid veal, because from a humane standpoint it upsets me. Same with ... can barely stand up because of it. I need to research that more. Probably I am eating those chickens.

Description : Green human beings without the need for food and agriculture - How realistic are genetically engineered posthumans relying on photosynthesis?

Last Answer : Would we have to stand in dirt all day, get covered in animal shit and not move?

Description : If genetically engineered humans were legalized, would you?

Last Answer : Maybe give myself red hair if I could change something on me. But honestly, yeah, I might guarantee intelligence and a predisposition to a healthy weight. The way I see it, it’s just active, conscious evolution. As for gender, no, I don’t care. :)

Description : Which is correct regarding genetically engineered insulin using E.coli ?

Last Answer : Which is correct regarding genetically engineered insulin using E.coli ? A. Difficulty in ... D. Insulin obtained varies in chemical structure

Description : In many stores what genetically engineered produce?

Last Answer : Need answer

Description : A genetically engineered form of brinjal known as the BT brinjal has been developed. The objective of this is (1) to make it pest resistant (2) to improve its taste and nutritive value (3) to make it drought resistant (4) to make its shelflife longer

Last Answer : (1) to make it pest resistant Explanation: Bt Brinjal is a genetically modified (GM) crop created by inserting Cry lAc gene from the soil bacterium Bacillus thuringiensis into Brinjal. The ... like the Brinjal Fruit and Shoot Borer (Leucinodes orbonalis) and Fruit Borer (Hell-coverpa armigera).

Description : A genetically engineered microorganism used successfully in bioremediation of oil spills is a species of (a) Trichoderma (b) Xanthomonas (c) Bacillus (d) Pseudomonas.

Last Answer : (d) Pseudomonas.

Description : A genetically engineered form of brinjal known as the BT brinjal has been developed. The objective of this is (1) to make it pest resistant (2) to improve its taste and nutritive value (3) to make it drought resistant (4) to make its shelflife longer

Last Answer : to make it pest resistant

Description : ALSO CHECK: Long-sight defect could be corrected by using ----- lens? Deficiency of vitamin B1 is causes-----? A. Rickets B. Bone Infection C. Beriberi (Answer) D. Myopia

Last Answer : C. Beriberi (Answer)

Description : All the following statements about obstructive jaundice are true except (A) Prothrombin time may be prolonged due to impaired absorption of vitamin K (B) Serum alkaline phosphatase may be raised ... systemic circulation due to biliary obstruction (D) There is no defect in conjugation of bilirubin

Last Answer : Answer : B

Description : Which one of the following statements is correct with respect to AIDS? (a) The HIV can be transmitted through eating food together with an infected person. (b) Drug addicts are least ... and nutrition. (d) The causative HIV retrovirus enters helper T-lymphocytes thus reducing their numbers.

Last Answer : (d) The causative HIV retrovirus enters helper T-lymphocytes thus reducing their numbers.

Description : Hyperargininemia, a defect in urea synthesis develops due to deficiency of the enzyme: (A) Ornithine transcarbamoylase (B) Argininosuccinase (C) Arginase (D) Argininosuccinate synthetase ENZYMES 157

Last Answer : Answer : B

Description : An important finding in glycinuria is (A) Excess excretion of oxalate in the urine (B) Deficiency of enzyme glycinase (C) Significantly increased serum glycine level (D) Defect in renal tubular reabsorption of glycine

Last Answer : Answer : D

Description : For the myopic eye, the defect is cured by

Last Answer : Concave lens

Description : Have you ever donated bone marrow? Either through harvesting or via apheresis of peripheral stem cells?

Last Answer : forgot the website for reading about the national registry. http://www.marrow.org/

Description : Blood cells are produced by Bone marrow in `:-`

Last Answer : Blood cells are produced by Bone marrow in `:-` A. All bones B. Some bones C. Most of the bones D. None

Description : Process by which blood cells are formed in bone marrow `:-`

Last Answer : Process by which blood cells are formed in bone marrow `:-` A. Haemopoiesis B. Haemolysis C. Thrombopoesis D. Erythroblastosis

Description : Vitamin B12 is (A) Not stored in the body (B) Stored in bone marrow (C) Stored in liver (D) Stored in RE cells

Last Answer : Answer : C

Description : An advantage of bleomycin over most antineoplastic drugs is its (a) Rapid onset of action (b) Lack of toxicity to all normal cells (c) Relative lack of bone marrow toxicity (d) Very broad spectrum of activity (e) Both (a) and (b)

Last Answer : Ans: C

Description : Red blood cells: a. measured 15 um in diameter b. do not contain mitochondria c. have a life span of 120 days in the circulation d. are released from the bone marrow as mature erythrocytes

Last Answer : do not contain mitochondria