Description : An inherited or acquired renal tubular defect in the reabsorption of phosphate (Vit D resistant ricket) is characterized with (A) Normal serum Phosphate (B) High serum phosphate (C ... blood phosphorous with elevated alkaline Phosphate (D) A high blood phosphorous with decreased alkaline phosphatase
Last Answer : Answer : C
Description : Renal ricket is caused by renal tubular defect (usually inherited) which interferes with reabsorption of (A) Calcium (B) Phosphorous (C) Sodium (D) Chloride
Last Answer : Answer : B
Description : In glycinuria daily urinary excretion of glycine ranges from (A) 100–200 mg (B) 300–500 mg (C) 600–1000 mg (D) 1100–1400 mg
Description : Para-amino hippurate excretion test is an indicator of (A) Glomerular filtration (B) Tubular secretion (C) Tubular reabsorption (D) Renal plasma flow
Last Answer : Answer : D
Description : Phenolsulphonephthalein excretion test is an indicator of (A) Glomerular filtration (B) Tubular secretion (C) Tubular reabsorption (D) Renal blood low
Description : Renal glycosuria occurs due to (A) Increased filtration of glucose in glomeruli (B) Increased secretion of glucose by renal tubular cells (C) Decreased reabsorption of glucose by renal tubular cells (D) Increased conversion of glycogen into glucose in tubular cells
Description : The most important effect of aldosterone is to (A) Increase the rate of tubular reabsorption of sodium (B) Decrease the rate of tubular reabsorption of potassium (C) Decrease the reabsorption of chloride (D) Decrease the renal reabsorption of sodium
Last Answer : Answer : A
Description : During compensation of respiratory alkalosis, all the following changes occur except (A) Decreased secretion of hydrogen ions by renal tubules (B) Increased excretion of sodium in urine (C) Increased excretion of bicarbonate in urine (D) Increased excretion of ammonia in urine
Description : Phlorizin inhibits (A) Renal tubular reabsorption of glucose (B) Glycolysis (C) Gluconeogenesis (D) Glycogenolysis
Description : Inulin clearance is a measure of (A) Glomerular filtration rate (B) Tubular secretion flow (C) Tubular reabsorption rate (D) Renal plasma flow
Description : Characteristics of Vitamin D and its metabolites include which one of the following? (a) Act to decrease serum levels of calcium (b) Activation of their Vitamin D receptors increases cellular CAMP ... Vitamin D increase renal excretion of calcium (e) Vitamin D deficiency results in Pager's disease
Last Answer : Ans: C
Description : All the following statements about obstructive jaundice are true except (A) Prothrombin time may be prolonged due to impaired absorption of vitamin K (B) Serum alkaline phosphatase may be raised ... systemic circulation due to biliary obstruction (D) There is no defect in conjugation of bilirubin
Description : Obligatory reabsorption of water (A) Is about 50% of the total tubular reabsorption of water (B) Is increased by antidiuretic hormone (C) Occurs in distal convoluted tubules (D) Is secondary to reabsorption of solutes
Description : PTH causes all of the following except (A) Increased intestinal absorption of calcium (B) Increased intestinal absorption of phosphate (C) Increased tubular reabsorption of calcium (D) Increased tubular reabsorption of phosphate
Description : Tubular reabsorption of calcium is increased by (A) Cholecalciferol (B) 25-Hydroxycholecalciferol (C) Calcitriol (D) All of these
Description : Pyridoxine deficiency can be diagnosed by measuring the urinary excretion of xanthurenic acid following a test dose of (A) Glycine (B) Histidine (C) Tryptophan (D) Pyridoxine
Description : Aldosterone increases Na+ reabsorption and K+ excretion in the renal collecting duct cells by: A. Inducing synthesis of Na+K+ATPase B. Inducing synthesis of amiloride sensitive Na+ channels C. Translocating Na+ channels from cytosolic site to luminal membrane D. All of the above
Last Answer : D. All of the above
Description : Urea clearance test is used to determine the (A) Glomerular filtration rate (B) Renal plasma flow (C) Ability of kidney to concentrate the urine (D) Measurement of tubular mass
Description : Which of the following concerning the pH of urine is correct? 1) is a useful indicator of the acid/base balance of the blood 2) rises on a vegetarian diet 3) is determined by the concentration of ... lower than 5.5 in renal tubular acidosis 5) would be above 7.0 after prolonged and severe vomiting
Last Answer : Answers-2 c - excretion of ammonium occurs when an acid urine is produced but the pH of urine is of course determined by the concentration of H+ ions d-unable to lower the pH to ... and distal nephron and this perpetuates the metabolic alkalosis until the fluid balance is restored with IV fluids.
Description : A simple way to assess tubular function is to withhold food and water for 12 hours and, then, measure (A) Serum urea (B) Serum creatinine (C) Urine output in one hour (D) Specific gravity of urine
Description : An important finding in Hyperammonemia type II is (A) Increased serum gluatmine level (B) Enlarged liver (C) Mental retardation (D) Increased carbamoyl phosphate synthetase level
Description : Thiazide diuretics enhance K+ elimination in urine primarily by: A. Inhibiting proximal tubular K+ reabsorption B. Inhibiting Na+ K+-2Cl- cotransport in the ascending limb of loop of Henle C ... in the distal tubular fluid to exchange with interstitial K+ D. Potentiating the action of aldosterone
Last Answer : C. Increasing the availability of Na+ in the distal tubular fluid to exchange with interstitial K
Description : In studies of the human body, which of the following terms is used to describe the first step in the production of urine? Is it: a) tubular secretion b) tubular reabsorption c) glomerular filtration d) none of these
Last Answer : ANSWER: C -- GLOMERULAR FILTRATION
Description : Anion gap is increased in (A) Renal tubular acidosis (B) Metabolic acidosis resulting from diarrhoea (C) Metabolic acidosis resulting from intestinal obstruction (D) Diabetic ketoacidosis
Description : A 60-year-old man was diagnosed last year with adenocarcinoma of the lung, and a 4 cm mass lesion was treated with a right lower lobectomy. He now has an ... 2) Membranous glomerulonephritis 3) Minimal change glomerulonephritis 4) Nodular glomerulosclerosis 5) Rapidly progressive glomerulonephritis
Last Answer : Answers-2 Most cases of membranous GN are idiopathic, but in some patients there is a history of an infection or a malignancy (usually lung) with antigenemia.
Description : he following is true of nifedipine except: A. It can aggravate urine voiding difficulty in elderly males with prostatic hypertrophy B. It promotes Na+ retention by a renal tubular action to ... release from pancreas D. At high doses it can paradoxically increase the frequency of angina pectori
Last Answer : B. It promotes Na+ retention by a renal tubular action to cause ankle oedema as side effect
Description : If a drug undergoes net tubular secretion, its renal clearance will be: A. More than the glomerular filtration rate B. Equal to the glomerular filtration rate C. Less than the glomerular filtration rate D. Equal to the rate of urine formation
Last Answer : A. More than the glomerular filtration rate
Description : An important finding in Histidinemia is (A) Impairment of conversion of α-Glutamate to α-ketoglutarate (B) Speech defect (C) Decreased urinary histidine level (D) Patients can not be treated by diet
Description : Increased serum alanine during fasting is due to (A) Breakdown of muscle proteins (B) Decreased utilization of non essential amino acids (C) Leakage of aminoacids to plasma (D) Impaired renal function
Description : Which of the following statement(s) is/are true concerning the assessment of protein reserve? a. Conventional serum proteins such as albumin and globulin are early indicators of malnutrition b. The ... d. Measurement of urea excretion in urine can be used as a measurement of protein breakdown
Last Answer : Answer: d Since protein is the functional and structural chemical of the body, most nutritional assessment techniques are estimates of protein reserves. The actual nitrogen balance can ... patients convert from reactive to anergic, and reactivity can be restored by nutritional repletion
Description : The following are true about aldosterone: a. it is secreted by the adrenal medulla b. its secretion is stimulated by decreased blood volume c. it stimulates active reabsorption of sodium in the distal renal tubules. d. it causes increased secretion of potassium by the distal renal tubules.
Last Answer : it causes increased secretion of potassium by the distal renal tubules.
Description : Actions of oxytocin include the following except: A. Vasoconstriction B. Increased water reabsorption in renal collecting ducts C. Contraction of mammary myoepithelium D. Release of prostaglandins from endometrium
Last Answer : A. Vasoconstriction
Description : Hyperargininemia, a defect in urea synthesis develops due to deficiency of the enzyme: (A) Ornithine transcarbamoylase (B) Argininosuccinase (C) Arginase (D) Argininosuccinate synthetase ENZYMES 157
Description : All of the following occur in orotic aciduria except (A) Increased synthesis of pyrimidine nucleotides (B) Increased excretion of orotic acid in urine (C) Decreased synthesis of cytidine triphosphate (D) Retardation of growth
Description : Mineralocorticoids increase the tubular reabsorption of (A) Sodium and calcium (B) Sodium and potassium (C) Sodium and chloride (D) Potassium and chloride 224 MCQs IN BIOCHEMISTRY
Description : Insulin decreases (A) Glycogenesis (B) Glyolysis (C) Gluconeogenesis (D) Tubular reabsorption of glucose
Description : Increased urinary excretion of orotic acid can occur in deficiency of (A) Orotate phosphoribosyl transferase (B) OMP decarboxylase (C) Mitochondrial ornithine transcarbamoylase (D) Any of the above
Description : Folic acid deficiency can be diagnosed by increased urinary excretion of (A) Methylmalonate (B) Figlu (C) Cystathionine (D) Creatinine
Description : All the following are true about phenylketonuria except (A) Deficiency of phenylalanine hydroxylase (B) Mental retardation (C) Increased urinary excretion of p-hydroxyphenyl pyruvic acid (D) Decrease serotonin formation
Description : Vasopressin (ADH) (A) Enhance facultative reabsorption of water (B) Decreases reabsorption of water (C) Increases excretion of calcium (D) Decreases excretion of calcium
Description : Among the following, a test of tubular function is (A) Creatinine clearance (B) Inulin clearance (C) PAH clearance (D) PSP excretion test
Description : Serum potassium level decreases in (A) Familial periodic paralysis (B) Addison’s disease (C) Renal failure (D) All of these
Description : Serum sodium level rises in all of the following except (A) Renal failure (B) Prolonged steroid therapy (C) Aldosteronism (D) Dehydration
Description : An increased serum ‘Iron’ and decreased ‘Fe’ binding capacity are found in (A) Fe-deficiency anaemia (B) Sideroblastic anaemia (C) Thalassaemia (D) Anaemia of chromic disorders
Description : An increased serum iron and decreased iron binding capacity is found in (A) Fe deficiency anemia (B) Sideroblastic anemia (C) Folate deficiency anemia (D) Sickle cell anemia
Description : The most important channel of elimination of digoxin is: A. Glomerular filtration B. Tubular secretion C. Hepatic metabolism D. Excretion in bile
Last Answer : A. Glomerular filtration
Description : Haemophilia is characterised by:** A. Daughters are affected from their carrier fathers B. Present on “y” chromosome C. Hemarthrosis is a common finding D. Deficiency of factor VII E. Neutrophil defect
Last Answer : C. Hemarthrosis is a common finding
Description : The probable metabolic defect in gents is (A) A defect in excretion of uric acid by kidney (B) An overproduction of pyrimidines (C) An overproduction of uric acid (D) Rise in calcium leading to deposition of calcium urate
Description : Hypolipidemic drugs reduce serum cholesterol and triacylglycerol. The effect of clofibrate is attributed to (A) Block in absorption from G.I.T. (B) Decrease in secretion of triacylglycerol and cholesterol ... by liver (C) Block in the reabsorption of bile acids (D) Decreased synthesis of cholesterol