Description : Which of the following is not likely to be the cause of failure of antimicrobial therapy of an acute infection: A. Improper selection of drug and dose B. Acquisition of resistance during treatment C. Failure to drain the pus D. Uncontrolled diabetes mellitus
Last Answer : B. Acquisition of resistance during treatment
Description : Prolonged lithium therapy can cause: A. Diabetes mellitus B. Goiter C. Parkinsonism D. Gout
Last Answer : B. Goiter
Description : Urinary water loss is increased in (A) Diabetes mellitus (B) Diabetes insipidus (C) Chronic glomerulonephritis (D) All of these
Last Answer : Answer : D
Description : Hypermagnesemia may be observed in (A) Hyperparathyroidism (B) Diabetes mellitus (C) Kwashiorkar (D) Primary aldosteronism
Last Answer : Answer : B
Description : Deficiency of magnesium may occur with (A) Alcoholism (B) Diabetes mellitus (C) Hypothyroidism (D) Advanced renal failure
Last Answer : Answer : A
Description : Alloxan can experimentally induce diabetes mellitus due to (A) Stimulation of α cells of the islets of langerhans (B) Necrosis of the β cells of the islets (C) Potentiation of insulinase activity (D) Epinephrine like action
Description : Hypoglycaemic coma can occur (A) In untreated diabetes mellitus (B) In starvation (C) After overdose of oral hypoglycaemic drugs (D) After overdose of insulin
Description : Diabetes mellitus can occur due to all of the following except (A) Deficient insulin secretion (B) Tumour of β−cells (C) Decrease in number of insulin receptors (D) Formation of insulin antibodies
Description : The rate of HMP shunt reactions is (A) Increased by Insulin (B) Increased in diabetes mellitus (C) Increased by glucagons (D) Increased in starvation
Description : Hypocholesterolemia is found in (A) Thyrotoxicosis (B) Diabetes mellitus (C) Obstructive jaundice (D) Nephrotic syndrome
Description : Ketosis is associated with the disease: (A) Nephritis (B) Diabetes mellitus (C) Edema (D) Coronary artery diseases
Description : Serum lipase level increases in (A) Paget’s disease (B) Gaucher’s disease (C) Acute pancreatitis (D) Diabetes mellitus
Last Answer : Answer : C
Description : Uremia occurs in (A) Cirrohsis of liver (B) Nephritis (C) Diabetes mellitus (D) Coronary thrombosis
Description : The essential fatty acids retard (A) Atherosclerosis (B) Diabetes mellitus (C) Nepritis (D) Oedema
Description : Which of the following condition is characterized by ketonuria but without glycosuria? (A) Diabetes mellitus (B) Diabetes insipidus (C) Prolonged starvation (D) Addison’s disease
Description : The β-lipoprotein fraction increases in severe (A) Diabetes Mellitus (B) Uremia (C) Nephritis (D) Muscular dystrophy
Description : Oliguria can occur in (A) Diabetes mellitus (B) Diabetes insipidus (C) Acute glomerulonephritis (D) Chronic glomerulonephritis
Description : Hypocholesterolaemia can occur in (A) Hyperthyroidism (B) Nephrotic syndrome (C) Obstructive jaundice (D) Diabetes mellitus FATS AND FATTY ACID METABOLISM 89
Description : All the following statements about ketone bodies are true except (A) Their synthesis increases in diabetes mellitus (B) They are synthesized in mitchondria (C) They can deplete the alkali reserve (D) They can be oxidized in the liver
Description : Obesity generally reflects excess intake of energy and is often associated with the development of (A) Nervousness (B) Non-insulin dependent diabetes mellitus (C) Hepatitis (D) Colon cancer
Description : Uremia occurs in (A) Cirrhosis of the liver(B) Nephritis (C) Diabetes mellitus (D) Coronary thrombosis
Description : In one of the following the quality of the protein synthesized is affected: (A) Diabetes mellitus (B) Gont (C) Multiple myeloma (D) Primaquine sensitivity
Description : Bence Jones proteins may be excreted in urine of patients suffering from (A) Tuberculosis (B) Diabetes mellitus (C) Multiple myeloma (D) Hyperthyroidism
Description : The following metabolic abnormalities occur in Diabetes mellitus except (A) Increased plasma FFA (B) Increased pyruvate carboxylase activate (C) Decreased lipogenesis (D) Decreased gluconeogenesis
Last Answer : B
Description : The absorption of glucose in the digestive tract (A) Occurs in the small intestine (B) Is stimulated by the hormone Glucagon (C) Occurs more rapidly than the absorption of any other sugar (D) Is impaired in cases of diabetes mellitus
Last Answer : A
Description : Two conditions in which gluconeogenesis is increased are (A) Diabetes mellitus and atherosclerosis (B) Fed condition and thyrotoxicosis (C) Diabetes mellitus and Starvation (D) Alcohol intake and cigarette smoking
Last Answer : C
Description : Physiological glycosuria is met with in (A) Renal glycosuria (B) Alimentary glycosuria (C) Diabetes Mellitus (D) Alloxan diabetes
Description : Gluconeogenesis is increased in the following condition: (A) Diabetes insipidus (B) Diabetes Mellitus (C) Hypothyroidism (D) Liver diseases
Description : Glucose tolerance is decreased in (A) Diabetes mellitus (B) Hypopituitarisme (C) Addison’s disease (D) Hypothyroidism
Description : Glucose tolerance is increased in (A) Diabetes mellitus (B) Adrenalectomy (C) Acromegaly (D) Thyrotoxicosis
Description : Specific gravity of urine is decreased in (A) Diabetes mellitus (B) Acute glomerulonephritis (C) Diarrhoea (D) Chronic glomerulonephritis
Description : Specific gravity of urine is raised in all of the following except (A) Diabetes mellitus (B) Diabetes insipidus (C) Dehydration (D) Acute glomerulonephritis
Last Answer : D
Description : Polyuria can occur in (A) Diabetes mellitus (B) Diarrhoea (C) Acute glomerulonephritis (D) High fever
Description : Restriction of salt intake is generally recommended in (A) Diabetes mellitus (B) Hypertension (C) Cirrhosis of liver (D) Peptic ulcer
Description : Obesity increases the risk of (A) Hypertension (B) Diabetes mellitus (C) Cardiovascular disease (D) All of these
Description : Renal threshold for glucose is decreased in (A) Diabetes mellitus (B) Insulinoma (C) Renal glycosuria (D) Alimentary glycosuria
Description : Specific gravity of urine increases in (A) Diabetes mellitus (B) Chronic glomerulonephritis (C) Compulsive polydypsia (D) Hypercalcemia
Description : An 16-year-old man presents with polyuria and polydipsia. Which of the following may confirm the diagnosis of diabetes mellitus? 1) A random plasma glucose of >7.5 mmol/L 2) A finding of 3+ ketonuria 3) An HbA1c of 7.0% 4) A fasting plasma glucose of 7.5 mmol/L 5) An abnormal glucose tolerance test
Last Answer : Answers-4 The diagnosis is usually relatively easy to confirm in a symptomatic subject. A random glucose of >11.1 mmol/L or a fasting glucose of >7.0 mmol/L would be regarded as ... haemoglobin (HbA1c) is also highly suggestive but not diagnostic. A glucose tolerance test is rarely needed.
Description : Which of the following conditions may be detectable by growth monitoring? 1) Hyperthyroidism 2) Hypothyroidism 3) Pseudohypoparathyroidism 4) XYY Syndrome 5) Insulin dependent diabetes mellitus
Last Answer : Answers-2
Description : A 16 year old male with a day history of malaise, weakness and vomiting. He was diagnosed with Insulin dependent diabetes mellitus 3 years prviously. Which ONE of the following supports a diagnosis of ... serum glucose 14 mmol/l 4) Decreased appetite in the past few days 5) Shallow respirations
Last Answer : Answers-2 a-An unusual but recognised feature particularly in children. However does not support a diagnosis of DKA. b-Suggests metabolic acidosis. c-'Normoglycaemic DKA' can occur and a glucose ... anorexia. e-Respiratory compensation leads to rapid deep (Kussmaul's) breathing. (Dr Mike Mulcahy)
Description : In diabetes mellitus, non-esterified fatty acid level in blood is increased, why?
Last Answer : Insulin inhibits hormone sensitive lipase, in diabetes, this inhibition is removed, so, more lipolysis is taking place.
Description : What are the chronic complications of diabetes mellitus?
Last Answer : Thrombosis, paralysis, gangrene, micro-angiopathy, nephrosclerosis, cataract, peripheral neuropathy.
Description : What are the acute complications of diabetes mellitus?
Last Answer : Keto acidosis, hyperosmolar non-ketotic coma, lactic acidosis.
Description : What is the reason for polyphagia in diabetes mellitus?
Last Answer : To compensate the loss of glucose and protein, patient takes more food.
Description : What is the reason for weight loss in diabetes mellitus?
Last Answer : The loss and ineffective utilisation of glucose leads to breakdown of fat and protein.ˇThis would lead to loss of weight.
Description : What is the reason for polydypsia in diabetes mellitus?
Last Answer : To compensate for this loss of water, thirst centre is activated, and more water is taken (polydypsia).
Description : What is the reason for polyuria in diabetes mellitus?
Last Answer : When the blood glucose level exceeds the renal threshold glucose is excreted in urine. Due to osmotic effect, more water accompanies the glucose.
Description : What are the cardinal symptoms of diabetes mellitus?
Last Answer : Polyuria, polydypsia, polyphagia and weight loss.
Description : What about type 2 diabetes mellitus?
Last Answer : Most of the patients belong to this type. Here circulating insulin level is normal, but there is a relative insulin deficiency. It is commonly seen in individuals above 40 years. These patients are less prone to developing ketosis.
Description : What are the characteristic features of type 1, diabetes mellitus?
Last Answer : Here circulating insulin level is deficient. These patients are dependent on insulin injections. Onset is during adolescence. Rapid loss of body weight is observed. They are more prone to developing ketosis.