Description : The following occur in untreated insulin dependent diabetes mellitus: a. diuresis b. decreased plasma amino acid c. increased plasma fatty acid d. ketonuria
Last Answer : ketonuria
Description : Choose the correct statement about nateglinide: A. It is a long acting oral hypoglycaemic drug B. Taken just before a meal, it limits postprandial hyperglycaemia in type 2 diabetes mellitus C. It lowers ... 1 and type 2 diabetes mellitus D. It acts by opening K+ channels in myocytes and adipocytes
Last Answer : B. Taken just before a meal, it limits postprandial hyperglycaemia in type 2 diabetes mellitus
Description : The rate of HMP shunt reactions is (A) Increased by Insulin (B) Increased in diabetes mellitus (C) Increased by glucagons (D) Increased in starvation
Last Answer : Answer : A
Description : Diabetes mellitus can occur due to all of the following except (A) Deficient insulin secretion (B) Tumour of β−cells (C) Decrease in number of insulin receptors (D) Formation of insulin antibodies
Last Answer : Answer : B
Description : Which of the following clinical characteristics is associated with Type 2 diabetes (previously referred to as non-insulin-dependent diabetes mellitus [NIDDM])? a) Can control blood glucose ... islet cell antibodies Individuals with Type 2 diabetes do not demonstrate islet cell antibodies.
Last Answer : a) Can control blood glucose through diet and exercise Oral hypoglycemic agents may improve blood glucose levels if dietary modification and exercise are unsuccessful.
Description : The following feature disfavours use of oral hypoglycaemics in diabetes mellitus: A. Age at onset of disease over 40 years B. Insulin requirement more than 40 U/day C. Fasting blood sugar level between 100–200 mg/dl D. Associated obesity
Last Answer : B. Insulin requirement more than 40 U/day
Description : The present status of oral hypoglycaemics in diabetes mellitus is: A. They are the first choice drug in all cases B. They should be prescribed only if the patient refuses insulin injections C. ... I diabetes mellitus D. They are used first in most uncomplicated mild to moderate type 2 diabetics
Last Answer : D. They are used first in most uncomplicated mild to moderate type 2 diabetics
Description : The major limitation of the thiazolidinediones in the treatment of type 2 diabetes mellitus is: A. Frequent hypoglycaemic episodes B. Hyperinsulinemia C. Lactic acidosis D. Low hypoglycaemic efficacy in moderate to severe cases
Last Answer : D. Low hypoglycaemic efficacy in moderate to severe cases
Description : Which of the following condition is characterized by ketonuria but without glycosuria? (A) Diabetes mellitus (B) Diabetes insipidus (C) Prolonged starvation (D) Addison’s disease
Last Answer : Answer : C
Description : Two conditions in which gluconeogenesis is increased are (A) Diabetes mellitus and atherosclerosis (B) Fed condition and thyrotoxicosis (C) Diabetes mellitus and Starvation (D) Alcohol intake and cigarette smoking
Last Answer : C
Description : In patients of hepatic cirrhosis: A. The extent of change in pharmacokinetics of drugs can be predicted from the values of liver function tests B. High doses of furosemide can be safely used C. Metformin is the preferred oral hypoglycaemic D. Disposition of atenolol is not significantly affected
Last Answer : D. Disposition of atenolol is not significantly affected
Description : Obesity generally reflects excess intake of energy and is often associated with the development of (A) Nervousness (B) Non-insulin dependent diabetes mellitus (C) Hepatitis (D) Colon cancer
Description : Which of the following conditions may be detectable by growth monitoring? 1) Hyperthyroidism 2) Hypothyroidism 3) Pseudohypoparathyroidism 4) XYY Syndrome 5) Insulin dependent diabetes mellitus
Last Answer : Answers-2
Description : A 16 year old male with a day history of malaise, weakness and vomiting. He was diagnosed with Insulin dependent diabetes mellitus 3 years prviously. Which ONE of the following supports a diagnosis of ... serum glucose 14 mmol/l 4) Decreased appetite in the past few days 5) Shallow respirations
Last Answer : Answers-2 a-An unusual but recognised feature particularly in children. However does not support a diagnosis of DKA. b-Suggests metabolic acidosis. c-'Normoglycaemic DKA' can occur and a glucose ... anorexia. e-Respiratory compensation leads to rapid deep (Kussmaul's) breathing. (Dr Mike Mulcahy)
Description : When the post-cardiac surgical patient demonstrates vasodilation, hypotension, hyporeflexia, slow gastrointestinal motility (hypoactive bowel sounds), lethargy, and respiratory depression, the nurse suspects ... and QT intervals, broad flat T waves), disorientation, depression, and hypotension.
Last Answer : a) Hypermagnesemia Untreated hypomagnesemia may result in coma, apnea, cardiac arrest.
Description : Deficiency of magnesium may occur with (A) Alcoholism (B) Diabetes mellitus (C) Hypothyroidism (D) Advanced renal failure
Description : Oliguria can occur in (A) Diabetes mellitus (B) Diabetes insipidus (C) Acute glomerulonephritis (D) Chronic glomerulonephritis
Description : Hypocholesterolaemia can occur in (A) Hyperthyroidism (B) Nephrotic syndrome (C) Obstructive jaundice (D) Diabetes mellitus FATS AND FATTY ACID METABOLISM 89
Description : The following metabolic abnormalities occur in Diabetes mellitus except (A) Increased plasma FFA (B) Increased pyruvate carboxylase activate (C) Decreased lipogenesis (D) Decreased gluconeogenesis
Last Answer : B
Description : Polyuria can occur in (A) Diabetes mellitus (B) Diarrhoea (C) Acute glomerulonephritis (D) High fever
Description : Oral mucosa and skin pigmentation occurs in patient with:** A. Diabetes mellitus B. Addison’s disease C. Multiple myeloma D. Squamous cell carcinoma E. Bright’s disease F. Cushing’s disease
Last Answer : B. Addison’s disease
Description : Intensive insulin therapy: A. Prevents the aggressive development of atherosclerosis in diabetic patients. B. Is not associated with unawareness of hypoglycemia. C. Improves peripheral neuropathy. D. ... . E. Is indicated in all patients with non-insulin-dependent diabetes mellitus (NIDDM).
Last Answer : Answer: C DISCUSSION: Intensive insulin therapy is indicated in patients with IDDM who can actively participate in their own management and the attainment of the goals set for ... or prevents progression of these complications; however, better glucose control may improve peripheral neuropathy
Description : A man suffering from diabetes mellitus drinks water more frequently as he has to eliminate from the blood extra (1) glucose (2) insulin (4) glucagon (4) salt
Last Answer : (1) glucose Explanation: The diabetic person has higher sugar in blood. Glucose is a form of sugar.
Description : Which one of the following pairs correctly matches a hormone with a disease resulting from its deficiency? (a) Luteinising - Failure of ovulation hormone (b) Insulin - Diabetes insipidus (c) Thyroxine - Tetany (d) Parathyroid - Diabetes mellitus hormone
Last Answer : (a) Luteinising - Failure of ovulation hormone
Description : Which one of the following pairs is incorrectly matched? (a) Glucagon – Beta cells (source) (b) Somatostatin – Delta cells (source) (c) Corpus luteum – Relaxin (secretion) (d) Insulin – Diabetes mellitus (disease
Last Answer : (a) Glucagon – Beta cells (source)
Description : Match the following hormones with their respective disease. (A) Insulin (i) Addison's disease (B) Thyroxin (ii) Diabetes insipidus (C) Corticoids (iii)Acromegaly (D) Growth hormone (iv) Goitre (v) Diabetes mellitus Select the correct option ... (iii) (c) (ii) (iv) (iii) (i) (d) (v) (iv) (i) (iii)
Last Answer : (d) (v) (iv) (i) (iii
Description : Which of the following clinical characteristics is associated with Type 1 diabetes (previously referred to as insulin-dependent diabetes mellitus [IDDM])? a) Presence of islet cell antibodies ... Requirement for oral hypoglycemic agents Individuals with Type 1 diabetes need insulin to preserve life.
Last Answer : a) Presence of islet cell antibodies Individuals with Type 1 diabetes often have islet cell antibodies.
Description : Which of the following statements is NOT true about diabetes mellitus? A) Type II diabetes is much more common than type I. B) Insulin injections are required in both type I and type II ... -sugar diet. E) Symptoms of diabetes include excessive thirst, frequent urination, and glucose in the urine.
Last Answer : B) Insulin injections are required in both type I and type II diabetes.
Description : The thiazolidinediones are mainly used as: A. Sole drug in type 1 diabetes mellitus B. Sole drug in type 2 diabetes mellitus C. Addon drug to a sulfonylurea and/or a biguanide in type 2 diabetes mellitus D. Addon drug to insulin in type 1 ... 18.34 1 8 . 3 4 B 18.35 1 8 . 3 5 D 18.36 1 8 . 3 6 C
Last Answer : C. Addon drug to a sulfonylurea and/or a biguanide in type 2 diabetes mellitus
Description : Choose the correct statement(s) about pioglitazone: A. It acts as an agonist on nuclear paroxisome proliferator receptor γ B. It enhances transcription of insulin responsive genes C. It lowers blood sugar in type 2 diabetes mellitus without causing hyperinsulinemia D. All of the above
Last Answer : D. All of the above
Description : Which of the following is not a sulfonylurea but acts by analogous mechanism to bring about quick and brief insulin release that is useful for normalizing meal time glycaemic excursions in type 2 diabetes mellitus: A. Glimepiride B. Miglitol C. Repaglinide D. Rosiglitazone
Last Answer : C. Repaglinide
Description : Insulin therapy is required for the following category/ categories of type 2 diabetes mellitus patients: A. Patients with ketoacidosis B. Patients undergoing surgery C. Pregnant diabetic D. All of the above
Description : Which of the following is not a specific indication for the more expensive monocomponent/human insulins: A. Insulin resistance B. Pregnant diabetic C. Sulfonylurea maintained diabetic posted for surgery D. Type 1 diabetes mellitus
Last Answer : D. Type 1 diabetes mellitus
Description : In a patient of diabetes mellitus maintained on insulin therapy, administration of the following drug can vitiate glycaemia control: A. Prednisolone B. Prazosin C. Paracetamol D. Phenytoin
Last Answer : A. Prednisolone
Description : Urine examination (Benedict’s test) of a 40 yr old obese male showed a brick red precipitate. This can result from all except Options: 1) Diabetes Mellitus 2) Drugs 3) Acute post-streptococcal glomerulonephritis 4) Cushing’s syndrome
Last Answer : Correct Answer: 3) Acute post-streptococcal glomerulonephritis
Description : The monocomponent insulin preparations differ from the conventional preparations in the following respects except: A. They are less allergenic B. They cause less hypoglycaemic reactions C. They cause less lipodystrophy D. They are less liable to induce insulin resistance
Last Answer : B. They cause less hypoglycaemic reactions
Description : he monocomponent insulin preparations differ from the conventional preparations in the following respects except: A. They are less allergenic B. They cause less hypoglycaemic reactions C. They cause less lipodystrophy D. They are less liable to induce insulin resistance
Description : Insulin receptors are decreased in number in (A) Obesity (B) Starvation (C) Hyperinsulinism (D) Kwashiorkor HORMONE METABOLISM 221
Description : Diabetes mellitus occur due to lack synthesis of hormon
Last Answer : Insuline
Description : Metabolic acidosis is caused in (A) Uncontrolled diabetes with ketosis (B) Pneumonia (C) Intestinal Obstruction (D) Hepatic coma
Description : Choose the correct statement about nonsteroidal antiinflammatory drugs (NSAIDs): A. NSAIDs attenuate hypoglycaemic action of sulfonylureas B. NSAIDs potentiate antihypertensive action of ACE inhibitors C. ... D. Combined therapy with prednisolone and NSAIDs carries higher risk of gastric bleeding
Last Answer : D. Combined therapy with prednisolone and NSAIDs carries higher risk of gastric bleeding
Description : All the following statements correctly describe ketone bodies except (A) They may result from starvation (B) They are present at high levels in uncontrolled diabetes (C) They include—OH β-butyrate and acetone (D) They are utilized by the liver during long term starvation
Last Answer : Answer : D
Description : Oral neomycin is beneficial in hepatic coma because: A. In hepatic failure patients it is absorbed from the intestines B. It decreases ammonia production by gut bacteria C. It reacts chemically with ... gut to prevent its diffusion into blood D. It induces ammonia detoxifying enzymes in the liver
Last Answer : B. It decreases ammonia production by gut bacteria
Description : Urinary water loss is increased in (A) Diabetes mellitus (B) Diabetes insipidus (C) Chronic glomerulonephritis (D) All of these
Description : Hypermagnesemia may be observed in (A) Hyperparathyroidism (B) Diabetes mellitus (C) Kwashiorkar (D) Primary aldosteronism
Description : Alloxan can experimentally induce diabetes mellitus due to (A) Stimulation of α cells of the islets of langerhans (B) Necrosis of the β cells of the islets (C) Potentiation of insulinase activity (D) Epinephrine like action
Description : Hypocholesterolemia is found in (A) Thyrotoxicosis (B) Diabetes mellitus (C) Obstructive jaundice (D) Nephrotic syndrome
Description : Ketosis is associated with the disease: (A) Nephritis (B) Diabetes mellitus (C) Edema (D) Coronary artery diseases