How N-acetyl neuraminic acid (sialic acid) is synthesised? 

1 Answer

Answer :

N-acetyl mannosamine-6-phosphate + phospho enol pyruvate.

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Description : Which of the following is present as a marker in lysosomal enzymes to direct them to their destination? (A) Glucose-6-phosphate (B) Mannose-6-phosphate (C) Galactose-6-phosphate (D) N-Acetyl neuraminic acid

Last Answer : Answer : C

Description : Carbamoyl phosphate synthetase structure is marked by change in the presence of (A) N-Acetyl glutamate (B) N-Acetyl Aspartate (C) Neuraminic acid (D) Oxalate

Last Answer : Answer : A

Description : Glycoproteins are marked for destruction by removal of their (A) Oligosaccharide prosthetic group (B) Sialic acid residues (C) Mannose residues (D) N-terminal amino acids

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Description : N-acetylneuraminic acid is an example of (A) Sialic acid (B) Mucic acid (C) Glucuronic acid (D) Hippuric acid

Last Answer : C

Description : Which statement is wrong for Krebs' cycle? (a) There is one point in the cycle where FAD+ is reduced to FADH2. (b) During conversion of succinyl CoA to succinic acid, a molecule of GTP is synthesised. (c ... citric acid. (d) There are three points in the cycle where NAD+ is reduced to NADH + H+.

Last Answer : (c) The cycle starts with condensation of acetyl group (acetyl CoA) with pyruvic acid to yield citric acid.

Description : Proteoglycans are made up of proteins and (A) Glucosamine (B) Mannosamine (C) Sialic acid (D) Mucopolysaccharides

Last Answer : Answer : D

Description : All the following are constituents of ganglioside molecule except (A) Glycerol (B) Sialic acid (C) Hexose sugar (D) Sphingosine

Last Answer : Answer : A

Description : The combination of an amino alcohol, fatty acid and sialic acid form (A) Phospholipids (B) Sulpholipids (C) Glycolipids (D) Aminolipids

Last Answer : Answer : C

Description : Gangliosides derived from glucosylceramide contain in addition one or more molecules of (A) Sialic acid (B) Glycerol (C) Diacylglycerol (D) Hyaluronic acid

Last Answer : Answer : A

Description : I-cell disease results from absence of the following from lysosomal enzymes: (A) Signal sequence (B) Mannose-6-phosphate (C) Sialic acid (D) A serine residue

Last Answer : Answer : D

Description : Sialic acids are present in (A) Proteoglycans (B) Glycoproteins (C) Both (A) and (B) (D) None of these

Last Answer : Answer : B

Description : The number of milliliters of 0.1 N KOH required to neutralize the insoluble fatty acids from 5 gms of fat is called (A) Acid number (B) Acetyl number (C) Halogenation (D) Polenske number

Last Answer : Answer : D

Description : The number of ml of N/10 KOH required to neutralize the fatty acids in the distillate from 5 gm of fat is called (A) Reichert-Meissel number (B) Polenske number (C) Acetyl number (D) Non volatile fatty acid number

Last Answer : Answer : A

Description : The repeating unit in hyaluronic acid is (A) Glucuronic acid and Galactosamine (B) Glucuronic acid are glucosamine (C) Glucuronic acid and N-acetyl glucosamine (D) Glucuronic acid and N-acetyl galactosamine

Last Answer : Answer : C

Description : In urea synthesis, the amino acid functioning solely as an enzyme activator: (A) N-acetyl glutamate(B) Ornithine (C) Citrulline (D) Arginine

Last Answer : Answer : A

Description : Repeating units of hyaluronic acid are (A) N-acetyl glucosamine and D-glucuronic acid (B) N-acetyl galactosamine and D-glucuronic acid (C) N-acetyl glucosamine and galactose (D) N-acetyl galactosamine and L- iduronic acid

Last Answer : A

Description : Which amino acid is synthesised after it gets in- corporated into the protein?

Last Answer : Hydroxyproline

Description : The metabolite which sustains urea cycle is (A) Ornithine (B) Citrulline (C) Carbamoyl phosphate (D) n-acetyl glutamate

Last Answer : Answer : C

Description : Transfer of the carbamoyl moiety of carbamoyl phosphate to ornithine is catalysed by a liver mitochondrial enzyme: (A) Carbamoyl phosphate synthetase (B) Ornithine transcarbamoylase (C) N-acetyl glutamate synthetase (D) N-acetyl glutamate hydrolase

Last Answer : Answer : B

Description : Penicillins interfere with bacterial cell wall synthesis by (a) Inhibiting synthesis of N-acetyl muramic acid pentapeptide (b) Inhibiting conjugation between N-acetyl muramic acid and N-acetyl ... link the peptidoglycan residues (d) Counterfeiting for D-alanine in the bacterial cell wall

Last Answer : Ans: C

Description : Peptidoglycan is also known as A- N-acetyl muramic acid B- mureinmucopeptide C- N acetylglucosamine D- mesodiaminopimetic acid

Last Answer : mureinmucopeptide

Description : Penicillins interfere with bacterial cell wall synthesis by: A. Inhibiting synthesis of N-acetyl muramic acid pentapeptide B. Inhibiting conjugation between N-acetyl muramic acid and N-acetyl ... cross link the peptidoglycan residues D. Counterfeiting for D-alanine in the bacterial cell wall

Last Answer : C. Inhibiting transpeptidases and carboxypeptidases which cross link the peptidoglycan residues

Description : Insulin regulates fatty acid synthesis by (A) Dephosphorylating of acetyl CoA carboxylase (B) Activating phosphorylase (C) Inhibiting malonyl CoA formation (D) Controlling carnitine-Acyl CoA transferase activity

Last Answer : Answer : A

Description : The enzyme regulating extramitochondrial fatty acid synthesis is (A) Thioesterase (B) Acetyl CoA carboxylase (C) Acyl transferase (D) Multi-enzyme complex

Last Answer : Answer : B

Description : A cofactor required for the conversion of acetyl-CoA to malonyl-CoA in extramitochondrial fatty acid synthesis is (A) Biotin (B) FMN (C) NAD (D) NADP

Last Answer : Answer : A

Description : The protein, which is in fact a multifunctional enzyme complex in higher organism is (A) Acetyl transacylase (B) Malonyl transacylase (C) 3-Hydroxy acyl-ACP dehyratase (D) Fatty acid synthase

Last Answer : Answer : D

Description : For each of the first 7-acetyl-CoA molecules formed by α-oxidation of palmitic acid, the yield of high energy phosphates is (A) 12 (B) 24 (C) 30 (D) 35

Last Answer : Answer : D

Description : A carrier molecule in the citric acid cycle is (A) Acetyl-CoA (B) Citrate (C) Oxaloacetate (D) Malate

Last Answer : Answer : C

Description : The initial step of the citric acid cycle is (A) Conversion of pyruvate to acetyl-CoA (B) Condensation of acetyl-CoA with oxaloacetate (C) Conversion of citrate to isocitrate (D) Formation of α -ketoglutarate catalysed by isocitrate dehydrogenase

Last Answer : Answer : B

Description : Choline is not required for the formation of (A) Lecithins (B) Acetyl choline (C) Sphingomyelin (D) Cholic acid

Last Answer : Answer : D

Description : Oxidative degradation of acetyl CoA in the citric acid cycle gives a net yield of all the following except (A) FADH2 (B) 3 NADH (C) 2 ATP (D) 2CO2

Last Answer : Answer : C

Description : During each cycle of on going fatty acid oxidation, all the following compounds are generated except (A) H2O (B) Acetyl CoA (C) Fatty acyl CoA (D) NADH FATS AND FATTY ACID METABOLISM 103

Last Answer : Answer : A

Description : Acetyl CoA required for extra mitochondrial fatty acid synthesis is produced by (A) Pyruvate dehydrogenase complex (B) Citrate lyase (C) Thiolase (D) Carnitine-acyl transferase

Last Answer : Answer : B

Description : β-Oxidation of odd-carbon fatty acid chain produces (A) Succinyl CoA (B) Propionyl CoA (C) Acetyl CoA (D) Malonyl CoA

Last Answer : Answer : D

Description : In synthesis of Triglyceride from α-Glycero phosphate and acetyl CoA, the first intermediate formed is (A) β-diacyl glycerol (B) Acyl carnitine (C) Monoacyl glycerol(D) Phosphatidic acid

Last Answer : Answer : D

Description : Which of the following cofactors or their derivatives must be present for the conversion of acetyl CoA to malonyl CoA extramitochondrial fatty acid synthesis? (A) Biotin (B) FAD (C) FMN (D) ACP

Last Answer : Answer : A

Description : As a result of each oxidation a long chain fatty acid is cleaved to give (A) An acid with 3-carbon less and propionyl CoA (B) An acid with 2-carbon less and acetyl CoA (C) An acid with 2-carbon less and acetyl CoA (D) An acid with 4-carbon and butyryl CoA

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Description : All long chain fatty acids with even number of carbon atoms are oxidized to a pool of _________ by β-oxidation. (A) CO2 (B) Propionic acid (C) Acetic acid (D) Acetyl CoA

Last Answer : Answer : D

Description : Iodine number denotes (A) Degree of unsaturation (B) Saponification number (C) Acid number (D) Acetyl number

Last Answer : Answer : A

Description : Saponification number indicates (A) Unsaturation in fat (B) Average M.W of fatty acid (C) Acetyl number (D) Acid number

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Description : For extramitochondrial fatty acid synthesis, acetyl CoA may be obtained from (A) Citrate (B) Isocitrate (C) Oxaloacetate (D) Succinate

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Description : Acetyl CoA carboxylase regulates fatty acid synthesis by which of the following mechanism? (A) Allosteric regulation (B) Covalent modification (C) Induction and repression (D) All of these

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Description : The conversion of pyruvate to acetyl CoA and CO2 (A) Is reversible (B) Involves the participation of lipoic acid (C) Depends on the coenzyme biotin (D) Occurs in the cytosol

Last Answer : B

Description : Acetyl CoA is not used for the synthesis of (A) Fatty acid (B) Cholesterol (C) Pyruvic acid (D) Citric acid

Last Answer : C

Description : Before pyruvic acid enters the TCA cycle it must be converted to (A) Acetyl CoA (B) Lactate (C) α-ketoglutarate (D) Citrate

Last Answer : A

Description : Which of the following metabolite integrates glucose and fatty acid metabolism? (A) Acetyl CoA (B) Pyruvate (C) Citrate (D) Lactate

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Description : Acetyl CoA from mitochondria is transferred to cytoplasm for the de novo synthesis of fatty acid, by which enzyme?

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Description : Androgens are synthesised in (A) Leydig cells in testes (B) Sertoli cells in testes (C) Seminiferous tubules (D) Prostate gland

Last Answer : Answer : A

Description : All the following statements about transcortin are true except (A) It is synthesised in liver (B) It transports glucocorticoids (C) It transports aldosterone (D) It transports progesterone

Last Answer : Answer : C

Description : Steroid hormones are synthesised from (A) Cholesterol (B) 7-Dehydrocholesterol (C) Calcitriol (D) 7-Hydroxycholesterol

Last Answer : Answer : A