Description : Which of the following is present as a marker in lysosomal enzymes to direct them to their destination? (A) Glucose-6-phosphate (B) Mannose-6-phosphate (C) Galactose-6-phosphate (D) N-Acetyl neuraminic acid
Last Answer : Answer : C
Description : In I-cell disease, lysosomal enzymes (A) Are not synthesised (B) Are inactive (C) Lack signal sequence (D) Cannot reach lysosomes
Last Answer : Answer : B
Description : Glycoproteins are marked for destruction by removal of their (A) Oligosaccharide prosthetic group (B) Sialic acid residues (C) Mannose residues (D) N-terminal amino acids
Last Answer : Answer : D
Description : The amino terminal of all polypeptide chain at the time of synthesis in E. coli is tagged to the amino acid residue: (A) Methionine (B) Serine (C) N-formyl methinine(D) N-formal serine
Description : Covalent modification of an enzyme usually involves phosphorylation / dephosphorylation of (A) Serine residue (B) Proline residue (C) Hydroxylysine residue (D) Hydroxyproline residue
Last Answer : Answer : A
Description : Tarui disease is characterized by the deficiency of the enzyme: (A) Liver phosphorylase (B) Muscle phosphorylase (C) Muscle and erythrocyte phosphofructokinase (D) Lysosomal acid maltase
Description : Both folic acid and methyl cobalamin (vitamin B12) are required in (A) Deamination of serine (B) Deamination of threonine (C) Conversion of pyridoxal phosphate to pyridoxamine phosphate (D) Methylation of homocystein to methionine
Description : Hyperammonaemia type I results from congenital absence of (A) Glutamate dehydrogenase (B) Carbamoyl phosphate synthetase (C) Ornithine transcarbamoylase (D) None of these
Description : Phospholipase A2 is an enzyme which removes a fatty acid residue from lecithin to form (A) Lecithin fragments (B) Phosphotidic acid (C) Glyceryl phosphate (D) Lysolecithin
Description : Activation or inactivation of certain key regulatory enzymes is accomplished by covalent modification of the amino acid: (A) Tyrosine (B) Phenylalanine (C) Lysine (D) Serine
Description : Viropexis takes place in the phagocytic vacuoles and is due to the action of Enzymes A- DNA gyrase B- lysosomal protease C- lysosomal lipase D- all of these
Last Answer : lysosomal protease
Description : The most important mechanism of antiinflammatory action of glucocorticoids is: A. Inhibition of lysosomal enzymes B. Restriction of recruitment of inflammatory cells at the site of inflammation C. Antagonism of action of interleukins D. Suppression of complement function
Last Answer : B. Restriction of recruitment of inflammatory cells at the site of inflammation
Description : Maple syrup urine disease results from absence or serve deficiency of (A) Homogentisate oxidase (B) Phenylalanine hydroxylase (C) Branched chain amino acid transaminase (D) None of these
Description : A coenzyme required for the synthesis of glycine from serine is (A) ATP (B) Pyridoxal phosphate (C) Tetrahydrofolate (D) NAD
Description : Proteoglycans are made up of proteins and (A) Glucosamine (B) Mannosamine (C) Sialic acid (D) Mucopolysaccharides
Description : All the following are constituents of ganglioside molecule except (A) Glycerol (B) Sialic acid (C) Hexose sugar (D) Sphingosine
Description : The combination of an amino alcohol, fatty acid and sialic acid form (A) Phospholipids (B) Sulpholipids (C) Glycolipids (D) Aminolipids
Description : Gangliosides derived from glucosylceramide contain in addition one or more molecules of (A) Sialic acid (B) Glycerol (C) Diacylglycerol (D) Hyaluronic acid
Description : N-acetylneuraminic acid is an example of (A) Sialic acid (B) Mucic acid (C) Glucuronic acid (D) Hippuric acid
Last Answer : C
Description : How N-acetyl neuraminic acid (sialic acid) is synthesised?
Last Answer : N-acetyl mannosamine-6-phosphate + phospho enol pyruvate.
Description : Pompe ’s d isease is caused due to deficiency of (A) Lysosomal α-1→4 and 1→6-glucosidase (B) Glucose-6-phosphatase (C) Glycogen synthase (D) Phosphofructokinase
Description : Of the following hemolytic anemias, which is categorized as inherited? a) Sickle cell anemia Glucose 6-phosphate dehydrogenase deficiency is an inherited abnormality resulting in hemolytic anemia. b ... is an acquired anemia. d) Hypersplenism Hypersplenism results in an acquired hemolytic anemia.
Last Answer : a) Sickle cell anemia Glucose 6-phosphate dehydrogenase deficiency is an inherited abnormality resulting in hemolytic anemia.
Description : The common features of introns include all the following except (A) The base sequence begins with GU (B) The base sequence ends with AG (C) The terminal AG sequence is preceded by a purine rich tract of ten nucleotides (D) An adenosine residue in branch site participates in splicing
Description : If a gene mutation prevents formation of an enzyme normally used by a lysosomes, a disease may result known as (A) Lysosomal abstracted disease (B) Lysosomal secretory disease (C) Lysosomal storage disease (D) All A, B and C
Last Answer : (C) Lysosomal storage disease
Description : Sialic acids are present in (A) Proteoglycans (B) Glycoproteins (C) Both (A) and (B) (D) None of these
Description : Which one of the following enzymes requires a coenzyme derived from the vitamin whose structure is shown below? (A) Enoyl CoA hydratase (B) Phosphofructokinase (C) Glucose-6-phosphatase (D) Glucose-6-phosphate dehydrogenase
Description : Hemolytic anemia is caused by the deficiency of certain enzymes of the pentose phosphate pathway, the principal enzyme involved is (A) Glucose-6-phosphate dehydrogenase (B) Aldolase (C) Fructose 1, 6-bisphosphatase (D) Phosphohexose isomerase
Description : The enzymes involved in Phosphorylation of glucose to glucose 6- phosphate are (A) Hexokinase (B) Glucokinase (C) Phosphofructokinase (D) Both (A) and (B)
Last Answer : D
Description : An important feature of maple syrup urine disease is (A) Patient can not be treated by dietary regulation (B) Without treatment death, of patient may occur by the end of second year of life (C) Blood levels of leucine, isoleucine and serine are increased (D) Excessive brain damage
Description : Which one of the following statements concerning glucose-6-phosphate dehydrogenase deficiency is correct? (A) Young R.B.Cs, particularly reticulocytes, contain the highest enzyme activity cells show less enzyme ... PD gene (D) G-6-PD deficiency is precipitated by ingestion of drugs such as aspirin
Description : In the intestine the rate of absorption is highest for (A) Glucose and galactose (B) Fructose and mannose (C) Fructose and pentose (D) Mannose and pentose
Description : Selwanof’s test is positive in (A) Glucose (B) Fructose (C) Galactose (D) Mannose
Description : Invert sugar is (A) Lactose (B) Mannose (C) Fructose (D) Hydrolytic product of sucrose
Description : Starch and glycogen are polymers of (A) Fructose (B) Mannose (C) α−D-Glucose (D) Galactose
Description : Barfoed’s solution is not reduced by (A) Glucose (B) Mannose (C) Sucrose (D) Ribose
Description : D-Mannose is present in some plant products like (A) Resins (B) Pectins (C) Mucilage (D) Gums
Description : The following is actively absorbed in the intestine: (A) Fructose (B) Mannose (C) Galactose (D) None of these
Description : Which of the following is an epimeric pair? (A) Glucose and fructose (B) Glucose and galactose (C) Galactose and mannose (D) Lactose and maltose
Last Answer : B
Description : The constituent unit of inulin is (A) Glucose (B) Fructose (C) Mannose (D) Galactose
Description : Sucrose consists of (A) Glucose + glucose (B) Glucose + fructose (C) Glucose + galactose (D) Glucose + mannose
Description : All the enzymes required for de novo synthesis of pyrimidine nucleotides are cytosolic except (A) Carbamoyl phosphate synthetase (B) Aspartate transcarbamoylase (C) Dihydro-orotase (D) Dihydro-orotate dehydrogenase
Description : Orotic aciduria type I reflects the deficiency of enzymes: (A) Orotate phosphoribosyl transferase and orotidylate decarboxylase (B) Dihydroorotate dehydrogenase (C) Dihydroorotase (D) Carbamoyl phosphate synthetase
Description : Which of the following enzymes incorporates inorganic phosphate into the substrate? (A) Phosphoglycerate kinase (B) Glyceraldehyde-3-phosphate dehydrogenase (C) Pyruvate kinase (D) Enolase
Description : Regulation of some enzymes by covalent modification involves addition or removal of (A) Acetate (B) Sulphate (C) Phosphate (D) Coenzyme
Description : The pentose phosphate pathway protects erythrocytes against hemolysis by assisting the enzyme: (A) Superoxide dismutase (B) Catalase (C) Glutathionic peroxidase (D) Cytochrome oxidase ENZYMES 149
Description : The enzymes of the pentose phosphate pathway are found in the (A) Cytosol (B) Mitochondria (C) Nucleus (D) Endoplasmic reticulum
Description : One of the enzymes regulating glycolysis is (A) Phosphofructokinase (B) Glyceraldehyde-3-phosphate dehydrogenase (C) Phosphotriose isomerase (D) Phosphohexose isomerase
Description : Enzymes leading to the high energy phosphorylation of substrates during glycolysis include which of the following? (A) Phosphoglycerate kinase (B) Enolase (C) Pyruvate Kinase (D) Glyceraldehyde-3-phosphate dehydrogenase
Description : Cytosolic and mitochondrial carbamoyl phosphate synthetase have the following similarity: (A) Both use ammonia as a substance (B) Both provide carbamoyl phosphate for urea synthesis (C) Both require N-acetylglutamate as an activator (D) Both are allosteric enzymes
Description : In E. coli the chain initiating amino acid in protein synthesis is (A) N-formyl methionine(B) Methionine (C) Serine (D) Cysteine