How can the blood coagulation (clotting) process be described?

How can the blood coagulation (clotting) process be described?
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Blood clotting encompasses a sequence of chemical reactions whose respective products are enzymes that catalyze the following reactions (that is why the clotting reactions are called cascade reactions). In the plasma thromboplastinogen transforms into thromboplastin, a reaction triggered by tissue and platelet factors liberated after injury of the blood vessel. Thromboplastin then catalyzes along with calcium ions the transformation of prothrombin into thrombin. Thrombin then catalyzes a reaction that produces fibrin from fibrinogen. Fibrin, as an insoluble substance, precipitates to form a network that traps red blood cells and platelets forming the blood clot and containing the hemorrhage. Blood Questions - Image Diversity: clotting cascade
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Tests of coagulation are used to monitor anticoagulation treatment and detect intrinsic abnormalities in coagulation. Which of the following statement(s) is/are true concerning coagulation tests? a. Prothrombin time (PT) measures both the intrinsic and extrinsic clotting pathways and fibrinogen b. Activated partial thromboplastin time (aPTT) can be used to monitor both oral anticoagulation with Warfarin and intravenous anticoagulation with heparin c. Thrombin clotting time (TCT) is a measurement of the time it takes for exogenously administered thrombin to turn plasma fibrinogen into fibrin clot d. Whole blood activated clotting time (ACT) is a measurement of the ability of whole blood to clot and is used to monitor heparin levels intraoperatively during cardiovascular and peripheral vascu

Description : Tests of coagulation are used to monitor anticoagulation treatment and detect intrinsic abnormalities in coagulation. Which of the following statement(s) is/are true concerning ... is used to monitor heparin levels intraoperatively during cardiovascular and peripheral vascular operations

Last Answer : Answer: a, c, d Coagulation tests include prothrombin time (PT), which measures the intrinsic and extrinsic pathways of fibrinogen production and is the most common method for ... more while for peripheral vascular applications, values of 250 seconds or greater are considered appropriate

What is the organ where most of the clotting factors are produced? What is the role of vitamin K in the blood coagulation?

Description : What is the organ where most of the clotting factors are produced? What is the role of vitamin K in the blood coagulation?

Last Answer : Most of the clotting factors are produced in the liver. Vitamin K participates in the activation of several clotting factors and it is fundamental for the well-functioning of the blood coagulation.

The following are true about blood coagulation: a. heparin inhibits blood coagulation through its interference with vitamin K metabolism in the liver b. addition of vitamin K to freshly drawn blood delays clotting c. thrombin converts fibrinogen to fibrin d. platelets are essential for blood clot

Description : The following are true about blood coagulation: a. heparin inhibits blood coagulation through its interference with vitamin K metabolism in the liver b. addition of vitamin K to freshly drawn ... delays clotting c. thrombin converts fibrinogen to fibrin d. platelets are essential for blood clot

Last Answer : thrombin converts fibrinogen to fibrin

During the process of blood coagulation, vitamin K helps in

Description : During the process of blood coagulation, vitamin K helps in

Last Answer : During the process of blood coagulation, vitamin K helps in A. Formation of thromboplastin B. ... to thrombin D. Conversion of fibrinogen to fibrin

The exclusive function of iron in the body is confined to the process of (A) Muscular contraction (B) Nerve excitation (C) Cellular respiration (D) Blood coagulation

Description : The exclusive function of iron in the body is confined to the process of (A) Muscular contraction (B) Nerve excitation (C) Cellular respiration (D) Blood coagulation

Last Answer : Answer : C

When a wound occurs in humans, the platelets in th blood activate a substance which starts the clotting process. The substance which starts the clotting is: a) adenosine (pron: ah-den-ah-seen) b) histamine c) lecithin (pron: less-ah-thin) d) thrombin

Description : When a wound occurs in humans, the platelets in th blood activate a substance which starts the clotting process. The substance which starts the clotting is: a) adenosine (pron: ah-den-ah-seen) b) histamine c) lecithin (pron: less-ah-thin) d) thrombin

Last Answer : ANSWER: D -- Thrombin

Which Blood Cell Helps Blood Coagulation ?

Description : Which Blood Cell Helps Blood Coagulation ?

Last Answer : : Molecules help in blood clotting in the process of endophagositosis.

Assertion `:` Prothrombinase enzyme act as antiheparin Reason `:` Heparin prevent coagulation of blood in Blood vessels

Description : Assertion `:` Prothrombinase enzyme act as antiheparin Reason `:` Heparin prevent coagulation of blood in Blood vessels

Last Answer : Assertion `:` Prothrombinase enzyme act as antiheparin Reason `:` Heparin prevent coagulation of blood in ... D. If both Assertion & Reason are false.

Which of the following does not play a role in blood coagulation

Description : Which of the following does not play a role in blood coagulation

Last Answer : Which of the following does not play a role in blood coagulation A. Vitamin K B. Vitamin D C. Calcium ions D. Fibrinogen

Which of the following is an anticoagulant and checks blood coagulation in blood vessels?

Description : Which of the following is an anticoagulant and checks blood coagulation in blood vessels?

Last Answer : Which of the following is an anticoagulant and checks blood coagulation in blood vessels? A. Prothrombin B. Globulin C. Thromboplatin D. Heparin

Which of the following substances, if introdced into the blood system, would cause coagulation of blood at the site of its introduction

Description : Which of the following substances, if introdced into the blood system, would cause coagulation of blood at the site of its introduction

Last Answer : Which of the following substances, if introdced into the blood system, would cause coagulation of ... B. Fibronogen C. Heparin D. Prothrombin

Protein required for coagulation of blood is

Description : Protein required for coagulation of blood is

Last Answer : Protein required for coagulation of blood is A. haemoglobin B. Globulin C. Fibrinogen D. Albumin

Which is unrelated to blood coagulation ?

Description : Which is unrelated to blood coagulation ?

Last Answer : Which is unrelated to blood coagulation ? A. Fibrinogen B. Fibrin C. Bilirubin D. Calcium

The coagulation of blood occurs due to

Description : The coagulation of blood occurs due to

Last Answer : The coagulation of blood occurs due to A. Destruction of erythrocytes B. Destruction of leucocytes ... of fibrinogen into fibrin D. Formation of serum

A non-functional plasma enzyme is (A) Psudocholinesterase (B) Lipoprotein lipase (C) Proenzyme of blood coagulation (D) Lipase

Description : A non-functional plasma enzyme is (A) Psudocholinesterase (B) Lipoprotein lipase (C) Proenzyme of blood coagulation (D) Lipase

Last Answer : Answer : D

Laboratory monitoring of coagulation and anticoagulation includes testing of platelet function. Which of the following statements is/are true concerning tests of platelet function? a. A platelet count of 50,000/µL or more usually ensures hemostasis b. Bleeding time assays assessibility of platelets to perform hemostatic plugs and is determined from a sample of blood drawn in an EDTA coated test tube c. Aspirin therapy can be associated with a bleeding time in the range of 8–15 minutes d. Tests of platelet aggregation should be part of the standard preoperative evaluation of patients using aspirin

Description : Laboratory monitoring of coagulation and anticoagulation includes testing of platelet function. Which of the following statements is/are true concerning tests of platelet function? a. A ... platelet aggregation should be part of the standard preoperative evaluation of patients using aspirin

Last Answer : Answer: a, c Tests of platelet function include peripheral platelet counts, bleeding times, and platelet aggregation. Usually, a platelet count of 50,000/mL or more ensures adequate hemostasis ... is not available in most laboratories, probably because of the observer-dependent nature of the test

The evaluation of a patient scheduled for elective surgery should always include the following as tests of hemostasis and coagulation: A. History and physical examination. B. Complete blood count (CBC), including platelet count. C. Prothrombin time (PT) and activated partial thromboplastin time (APTT). D. Studies of platelet aggregation with adenosine diphosphate (ADP) and epinephrine.

Description : The evaluation of a patient scheduled for elective surgery should always include the following as tests of hemostasis and coagulation: A. History and physical examination. B. Complete blood count ( ... (APTT). D. Studies of platelet aggregation with adenosine diphosphate (ADP) and epinephrine.

Last Answer : Answer: A DISCUSSION: The evaluation of most patients scheduled for elective surgery who do not have a history of significant bleeding disorders is somewhat controversial. An adequate history and ... suspected of having qualitative defects of platelet function (e.g., von Willebrand's disease)

Which of the following statements about the preparation and storage of blood components is/are true? A. Solutions containing citrate prevent coagulation by binding calcium. B. The shelf life of packed red blood cells preserved with CPDA-1 is approximately 35 days at 1؛ to 6؛ C. C. There are normal numbers of platelets in packed red blood cells stored at 1؛ to 6؛ C for more than 2 days. D. The storage lesion affecting refrigerated packed red blood cells includes development of acidosis, hyperkalemia, and decreased intracellular 2,3DPG (diphosphoglycerate).

Description : Which of the following statements about the preparation and storage of blood components is/are true? A. Solutions containing citrate prevent coagulation by binding calcium. B. The ... cells includes development of acidosis, hyperkalemia, and decreased intracellular 2,3DPG (diphosphoglycerate).

Last Answer : Answer: ABD DISCUSSION: After blood has been collected from a donor, it is anticoagulated with a solution containing citrate, which acts by binding calcium. Blood is then separated into its ... transfusion or produce effects other than those predicted based on the content of the unit of blood

********* factor is involved in – (1) Blood Coagulation (2) Excretion (3) Digestion (4) Respiration

Description : Christmas factor is involved in – (1) Blood Coagulation (2) Excretion (3) Digestion (4) Respiration

Last Answer : (1) Blood Coagulation Explanation: Factor IX, also known as Christmas factor, is one of the serine proteases of the coagulation system; it belongs to peptidase family Sl. Deficiency of this ... young boy named Stephen Christmas was found to be lacking this exact factor, leading to haemophilia.

The vitamin necessary for coagulation of blood is – (1) Vitamin B (2) Vitamin C (3) Vitamin K (4) Vitamin E

Description : The vitamin necessary for coagulation of blood is – (1) Vitamin B (2) Vitamin C (3) Vitamin K (4) Vitamin E

Last Answer : (3) Vitamin K Explanation: Vitamin K is a group of structurally similar, fat-soluble vitamins that are needed for the posttranslational modification of certain proteins required for blood coagulation and ... amounts in green leafy vegetables) and vitamin K2 (form used by enzymes in animals).

Which of the following enzymes aids in coagulation of blood? (1) Tryptase (2) Pepsin (3) Rennin (4) Amylase

Description : Which of the following enzymes aids in coagulation of blood? (1) Tryptase (2) Pepsin (3) Rennin (4) Amylase

Last Answer : (3) Rennin Explanation: Amylase converts starch and glycogen into simple sugars. Pepsin is a digestive enzyme. Rennin, the active part of prorennin helps in coagulation of blood.

Which of the following blood cells is compulsory for blood coagulation? (1) Platelets (2) Red Blood Corpuscles (3) White Blood Corpuscles (4) Lymphocites

Description : Which of the following blood cells is compulsory for blood coagulation? (1) Platelets (2) Red Blood Corpuscles (3) White Blood Corpuscles (4) Lymphocites

Last Answer : (1) Platelets Explanation: Coagulation is the process by which blood forms clots. It is an important part of homeostasis, the cessation of blood loss from a damaged vessel, wherein a damaged ... vessel. Platelets immediately form a plug at the site of injury, this is called primary homeostasis.

The vitamin necessary for coagulation of blood is - (1) vitamin B (2) vitamin C (3) vitamin K (4) vitamin E

Description : The vitamin necessary for coagulation of blood is - (1) vitamin B (2) vitamin C (3) vitamin K (4) vitamin E

Last Answer : (3) vitamin K Explanation: Vitamin K is a group of structurally similar, fat-soluble vitamins that the human body requires for complete synthesis of certain proteins that are prerequisites for blood coagulation (K from Koagulation, German for "coagulation").

Bleeding time is increased in: a. massive blood transfusion b. vitamin K deficiency c. von Willebrand's disease d. disseminated intravascular coagulation (DIC)

Description : Bleeding time is increased in: a. massive blood transfusion b. vitamin K deficiency c. von Willebrand's disease d. disseminated intravascular coagulation (DIC)

Last Answer : disseminated intravascular coagulation (DIC)

The prothrombin time a. assess the extrinsic pathway of the blood coagulation cascade b. is prolonged in patients with fat absorption c. is increased by warfarin d. all above

Description : The prothrombin time a. assess the extrinsic pathway of the blood coagulation cascade b. is prolonged in patients with fat absorption c. is increased by warfarin d. all above

Last Answer : all above

The prothrombin time a. assess the extrinsic pathway of the blood coagulation cascade b. is prolonged in patients with fat absorption c. is increased by warfarin d. is increased by heparin

Description : The prothrombin time a. assess the extrinsic pathway of the blood coagulation cascade b. is prolonged in patients with fat absorption c. is increased by warfarin d. is increased by heparin

Last Answer : assess the extrinsic pathway of the blood coagulation cascade

The deficiency of which one of the following vitamins in the ration of Poultry birds increases the Coagulation time of blood and creates the danger of haemorrhage ? (A) Vitamin A (B) Vitamin B 1 (C) Vitamin K (D) Vitamin D (E) Vitamin B 6

Description : The deficiency of which one of the following vitamins in the ration of Poultry birds increases the Coagulation time of blood and creates the danger of haemorrhage ? (A) Vitamin A (B) Vitamin B 1 (C) Vitamin K (D) Vitamin D (E) Vitamin B 6

Last Answer : (D) Vitamin D

In which following help in blood cloathing or coagulation

Description : In which following help in blood cloathing or coagulation

Last Answer : k

he primary mechanism by which heparin prevents coagulation of blood is: A. Direct inhibition of prothrombin to thrombin conversion B. Facilitation of antithrombin III mediated inhibition of factor Xa and thrombin C. Activation of antithrombin III to inhibit factors IX and XI D. Inhibition of factors XIIa and XIIIa

Description : he primary mechanism by which heparin prevents coagulation of blood is: A. Direct inhibition of prothrombin to thrombin conversion B. Facilitation of antithrombin III mediated inhibition of factor Xa and ... of antithrombin III to inhibit factors IX and XI D. Inhibition of factors XIIa and XIIIa

Last Answer : B. Facilitation of antithrombin III mediated inhibition of factor Xa and thrombi

Select the action of vasopressin exerted through the V1 subtype receptors: A. Release of coagulation factor VIII and von Willebrands factor from vascular endothelium B. Increased peristalsis of gut C. Dilatation of blood vessels D. Increased water permeability of renal collecting ducts

Description : Select the action of vasopressin exerted through the V1 subtype receptors: A. Release of coagulation factor VIII and von Willebrands factor from vascular endothelium B. Increased peristalsis of gut C. Dilatation of blood vessels D. Increased water permeability of renal collecting ducts

Last Answer : B. Increased peristalsis of gut

In the mammalian body, this element plays many important roles. Try to identify this element with the fewest number of clues. This element is required to insure the integrity and permeability of cell membranes, to regulate nerve and muscle excitability, to help maintain normal muscular contraction, and to assure cardiac rhythmicity. It also plays a essential role in several of the enzymatic steps involved in blood coagulation and is the most important element of bone salt. Name this element.

Description : In the mammalian body, this element plays many important roles. Try to identify this element with the fewest number of clues. This element is required to insure the integrity and permeability of ... involved in blood coagulation and is the most important element of bone salt. Name this element.

Last Answer : ANSWER: Calcium 

1. Which book was written by Gandhiji? 2. Which vitamin is essential for the coagulation of blood? 3. Which describes India as a Secular State? 4. When the wind is deflected due to the rotation of the Earth, what is it called? 5. Which part of Delhi where Aibak laid the foundation of the first so called 'Seven cities' of medieval Delhi,?

Description : 1. Which book was written by Gandhiji? 2. Which vitamin is essential for the coagulation of blood? 3. Which describes India as a Secular State? 4. When the wind is deflected due to the ... is there? 20. Who was the first Mughal emperor to allow Britishers to establish trade links with India?

Last Answer : Answer : 1. My Experiments with Truth 2. Vitamin K3. Preamble to the Constitution4. Geostropic wind 5. Mehrauli 6. Lead 7. July 11 8. Pt. Jawahar Lal Nehru 9. 250 cms 10. Devaraya II 11. 45 g ... 13. 6 14. Sahara 15. Devagiri 16. 2009 17. Bachhendri Pal 18. Immunisation 19. Heavy 20. Jahangir

********* factor is involved in : (1) Blood Coagulation (2) Excretion (3) Digestion (4) Respiration

Description : Christmas factor is involved in : (1) Blood Coagulation (2) Excretion (3) Digestion (4) Respiration

Last Answer : Blood Coagulation

Which of the following enzymes aids in coagulation of blood? (1) Tryptase (2) Pepsin (3) Rennin (4) Amylase

Description : Which of the following enzymes aids in coagulation of blood? (1) Tryptase (2) Pepsin (3) Rennin (4) Amylase 

Last Answer : Rennin

The vitamin necessary for coagulation of blood is : (1) Vitamin B (2) Vitamin C (3) Vitamin K (4) Vitamin E

Description : The vitamin necessary for coagulation of blood is : (1) Vitamin B (2) Vitamin C (3) Vitamin K (4) Vitamin E

Last Answer : Vitamin K

Which vitamin helps in blood coagulation? (1) Vitamin-A (2) Vitamin-C (3) Vitamin-K (4) Vitamin-E

Description : Which vitamin helps in blood coagulation? (1) Vitamin-A (2) Vitamin-C (3) Vitamin-K (4) Vitamin-E

Last Answer : Vitamin-K

Which of the following blood cells is compulsory for blood coagulation ? (1) Platelets (2) Red Blood Corpuscles (3) White Blood Corpuscles (4) Lymphocites

Description : Which of the following blood cells is compulsory for blood coagulation ? (1) Platelets (2) Red Blood Corpuscles (3) White Blood Corpuscles (4) Lymphocites

Last Answer : Platelets

What triggers blood clotting? -Biology

Description : What triggers blood clotting? -Biology

Last Answer : answer:

What is blood clotting? -Biology

Description : What is blood clotting? -Biology

Last Answer : answer:

How do platelets initiate blood clotting? -Biology

Description : How do platelets initiate blood clotting? -Biology

Last Answer : answer:

What is the importance of prothrombin in blood clotting? -Biology

Description : What is the importance of prothrombin in blood clotting? -Biology

Last Answer : answer:

What are the factors that oppose blood clotting? -Biology

Description : What are the factors that oppose blood clotting? -Biology

Last Answer : answer:

Deficiency of which vitamin does not cause blood clotting? -General Knowledge

Description : Deficiency of which vitamin does not cause blood clotting? -General Knowledge

Last Answer : answer:

What is blood clotting ?

Description : What is blood clotting ?

Last Answer : The process by which fibrinogen is separated from the blood plasma from the wound site and stops the bleeding by forming fibrin reticulum in the wound site so that the residual blood becomes clot is called blood clotting or blood clotting.

What is the light residual part of the blood after blood clotting ?

Last Answer : Serum is the light residual part of the blood after blood clotting.

Assertion: Platelets play an important role in blood clotting. Reason: In the blood oozing from an injury, the platelets disintegrate and release thro

Description : Assertion: Platelets play an important role in blood clotting. Reason: In the blood oozing from an injury, the platelets disintegrate and release thro

Last Answer : Assertion: Platelets play an important role in blood clotting. Reason: In the blood oozing from an ... D. If both Assertion & Reason are false.

The following are needed for blood -clotting in mammals

Description : The following are needed for blood -clotting in mammals

Last Answer : The following are needed for blood -clotting in mammals A. `Ca^(++)` and Vitamin E B. `Ca^(++)` and ... +)` and Vitamin A D. `K^(+)` and Vitamin K

During blood clotting, which of the following is used?

Description : During blood clotting, which of the following is used?

Last Answer : During blood clotting, which of the following is used? A. Co B. `Ca^(+ +)` C. `Na^(+)` and thromboplastin D. `Cl^(-)`

Which of the following , does not help in clotting of blood ?

Description : Which of the following , does not help in clotting of blood ?

Last Answer : Which of the following , does not help in clotting of blood ? A. Heparin B. Prothrombin C. `Ca^(2+)` D. `Exposure to `O_(2)`

Blood clotting can be prevented in a test tube by adding a little

Description : Blood clotting can be prevented in a test tube by adding a little

Last Answer : Blood clotting can be prevented in a test tube by adding a little A. Sodium oxalate B. Sodium chloride C. Sodium hydroxide D. Ammonium chloride