Description : Substrate level phosphorylation in TCA cycle is in step: (A) Isocitrate dehydrogenase (B) Malate dehydrogenase (C) Aconitase (D) Succinate thiokinase
Last Answer : D
Description : NADPH is produced when this enzyme acts (A) Pyruvate dehydrogenase (B) Malic enzyme (C) Succinate dehydrogenase (D) Malate dehydrogenase
Last Answer : Answer : B
Description : Calcium is required for the activation of the enzyme: (A) Isocitrate dehydrogenase (B) Fumarase (C) Succinate thiokinase (D) ATPase
Last Answer : Answer : D
Description : Zinc is a constituent of the enzyme: (A) Succinate dehydrogenase (B) Carbonic anhydrase (C) Mitochondrial superoxide dismutase (D) Aldolase
Description : Transfer of reducing equivalents from succinate dehydrogenase to coenzyme Q is specifically inhibited by (A) Carboxin (B) Oligomycin (C) Piericidin A (D) Rotenone
Last Answer : Answer : A
Description : A specific inhibitor for succinate dehydrogenase is (A) Arsenite (B) Malonate (C) Citrate (D) Fluoride
Description : The inhibition of succinate dehydrogenase by malonate by (A) Competitive inhibition (B) Non-competitive inhibition (C) Uncompetitive inhibition (D) Feedback inhibition
Description : Which of the following is not having an apoenzyme and coenzyme? (A) Lactate dehydrogenase (B) Succinate dehydrogenase (C) Malate dehydrogenase (D) Pepsin
Description : Thiamine is essential for (A) Pyruvate dehydrogenase (B) Isocitrate dehydrogenase (C) Succinate dehydrogenase (D) Acetyl CoA synthetase ENZYMES 165
Description : All of the following are allosteric enzymes except (A) Citrate synthetase (B) a-Ketoglutarate dehdrogenase (C) Succinate thiokinase (D) Succinate dehydrogenase
Last Answer : Answer : C
Description : Malonate is an inhibitor of (A) Malate dehydrogenase (B) α-Ketoglutarate dehydrogenase (C) Succinate dehydrogenase (D) Isocitrate dehydrogenase
Description : In citric acid cycle, GDP is phosphorylated by (A) Succinate dehydrogenase (B) Aconitase (C) Succinate thiokinase (D) Fumarse
Description : A specific inhibitor for succinate dehydrogenase is (A) Arsenine (B) Arsenite (C) Citrate (D) Fluoride ENZYMES 147
Description : The enzyme using some other substance, not oxygen as hydrogen acceptor is (A) Tyrosinase (B) Succinate dehydrogenase (C) Uricase (D) Cytochrome oxidase
Description : An enzyme catalyzing oxidoreduction, using oxygen as hydrogen acceptor is (A) Cytochrome oxidase (B) Lactate dehydrogenase (C) Malate dehydrogenase (D) Succinate dehydrogenase
Description : NAD is required as a coenzyme for (A) Malate dehydrogenase (B) Succinate dehydrogenase (C) Glucose-6-phosphate dehydrogenase (D) HMG CoA reductae
Description : FAD is a coenzyme for (A) Succinate dehydrogenase (B) Glycerol-3-phosphate dehydrogenase (C) Sphingosine reductase (D) All of these
Description : With the exception of glycine all amino acids found in protein are (A) Isocitrate dehydrogenase (B) Fumarase (C) Succinate thiokinase (D) ATPase
Description : A specific inhibitor for succinate dehydrogenase is (A) Arsinite (B) Melouate (C) Citrate (D) Cyanide
Last Answer : B
Description : Fluoride inhibits ______ and arrests glycolysis. (A) Glyceraldehyde-3-phosphate dehydrogenase (B) Aconitase (C) Enolose (D) Succinate dehydrogenase
Last Answer : C
Description : Which of the following is located in the mitochondria? (A) Cytochrome oxidase (B) Succinate dehydrogenase (C) Dihydrolipoyl dehydrogenase (C) All of these
Description : All enzymes of TCA cycle are located in the mitochondrial matrix except one which is located in inner mitochondrial membranes in eukaryotes and in cytosol in prokaryotes. This enzyme is (a) isocitrate dehydrogenase (b) malate dehydrogenase (c) succinate dehydrogenase (d) lactate dehydrogenase.
Last Answer : (c) succinate dehydrogenase
Description : Select the option which is not correct with respect to enzyme action. (a) Substrate binds with enzyme at its active site. (b) Addition of lot of succinate does not reverse the inhibition ... from that which binds the substrate. (d) Malonate is a competitive inhibitor of succinic dehydrogenase.
Last Answer : (b) Addition of lot of succinate does not reverse the inhibition of succinic dehydrogenase by malonate.
Description : Which of the following is located in the mitochondria? (A) Cytochrome oxidase (B) Succinate dehydrogenase (C) Dihydrolipoyl dehydrogenase (D) All of these
Last Answer : (D) All of these
Description : This catalyzes formation of CoA derivatives from fatty acid, CoA and ATP: (A) Acyl CoA dehydrogenase (B) Enoyl hydrase (C) β-OH acyl CoA dehydrogenase (D) Thio kinase
Description : Formation of acetyl CoA from pyruvate for de novo synthesis of fatty acids requires (A) Pyruvate dehydrogenase complex (B) Citrate synthetase (C) ATP citrate lyase (D) All of these
Description : Isocitrate dehydrogenase is allosterically inhibited by (A) Oxalosuccinate (B) α-Ketoglutarate (C) ATP (D) NADH
Description : An allosteric inhibitor of pyruvate dehydrogenase is (A) Acetyl CoA (B) ATP (C) NADH (D) Pyruvate
Description : The reaction catalysed by α-ketoglutarate dehydrogenase in the citric acid cycle requires (A) NAD (B) NADP (C) ADP (D) ATP
Description : Acyl-CoA dehydrogenase converts Acyl CoA to α-β unsaturated acyl-CoA in presence of the coenzyme: (A) NAD+ (B) NADP+ (C) ATP (D) FAD
Description : Allsoteric activator of glutamate dehydrogenase is (A) ATP (B) GTP (C) ADP and GDP (D) AMP and GMP
Description : Allosteric inhibitor of glutamate dehydrogenase is (A) ATP (B) ADP (C) AMP (D) GMP
Description : The initial step of the citric acid cycle is (A) Conversion of pyruvate to acetyl-CoA (B) Condensation of acetyl-CoA with oxaloacetate (C) Conversion of citrate to isocitrate (D) Formation of α -ketoglutarate catalysed by isocitrate dehydrogenase
Description : Acetyl-CoA is the principal building block of fatty acids. It is produced within the mitochondria and does not diffuse readily into cytosol. The availability of acetyl CoA involves (A) Carnitine acyl transferase (B) Pyruvate dehydrogenase (C) Citrate lyase (D) Thiolase
Description : Acetyl CoA required for extra mitochondrial fatty acid synthesis is produced by (A) Pyruvate dehydrogenase complex (B) Citrate lyase (C) Thiolase (D) Carnitine-acyl transferase
Description : A key substance in the committed step of pyrimidines biosynthesis is (A) Ribose-5-phosphate (B) Carbamoyl phosphate (C) ATP (D) Glutamine
Description : The number of ATP produced in the oxidation of 1 molecule of NADPH in oxidative phosphorylation is (A) Zero (B) 2 (C) 3 (D) 4
Description : The number of molecules of ATP produced by the total oxidation of acetyl CoA in TCA cycle is (A) 6 (B) 8 (C) 10 (D) 12
Description : Heme is synthesized from (A) Succinyl-CoA and glycine (B) Active acetate and glycine (C) Active succinate and alanine (D) Active acetate and alanine
Description : Reducing equivalents from succinate enter the mitochondrial respiratory chain at (A) NAD (B) Coenzyme Q (C) FAD (D) Cyt c
Description : Among citric acid cycle enzymes, a flavoprotein is (A) Malate (B) Fumarase (C) Succinate dehrogenase (D) Isocitrate dehrogenase
Description : In gluconeogensis, an allosteric activator required in the synthesis of oxaloacetate from bicarbonate and pyruvate, which is catalysed by the enzyme pyruvate carboxylase is (A) Acetyl CoA (B) Succinate (C) Isocitrate (D) Citrate
Description : The reaction of Kreb’s cycle which does not require cofactor of vitamin B group is (A) Citrate isocitrate (B) α -Ketoglutarate succinate (C) Malate oxaloacetate (D) Succinate fumarate
Description : Fluoroacetate inhibits the reaction of citric acid cycle: (A) Isocitrate α-Ketoglutarate (B) Fumarate α-Malate (C) Citrate α-cis-aconitate (D) Succinate α-fumarate
Description : The example of generation of a high energy phosphate at the substrate level in the citric acid cycle is the reaction: (A) Isocitrate α-Ketoglutarate (B) Succinate α-fumarate (C) Malate α-oxaloacetate (D) Succinyl CoA α-Succinate
Description : An example of ligases is (A) Succinate thiokinase (B) Alanine racemase (C) Fumarase (D) Aldolase
Description : For extramitochondrial fatty acid synthesis, acetyl CoA may be obtained from (A) Citrate (B) Isocitrate (C) Oxaloacetate (D) Succinate
Description : The following ketoacid is involved in fixing dietary NH3 into amino acid: (A) Pyruvate (B) Oxalo acetate (C) Oxalo succinate (D) α-keto glutarate
Description : A compound serving a link between citric acid cycle and urea cycle is (A) Malate (B) Citrate (C) Succinate (D) Fumarate
Description : An aneplerotic reaction which sustains the availability of oxaloacetate is the carboxylation of (A) Glutamate (B) Pyruvate (C) Citrate (D) Succinate