In I-cell disease, lysosomal enzymes (A) Are not synthesised (B) Are inactive (C) Lack signal sequence (D) Cannot reach lysosomes

In I-cell disease, lysosomal enzymes (A) Are not synthesised (B) Are inactive (C) Lack signal sequence (D) Cannot reach lysosomes
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I-cell disease results from absence of the following from lysosomal enzymes: (A) Signal sequence (B) Mannose-6-phosphate (C) Sialic acid (D) A serine residue

Description : I-cell disease results from absence of the following from lysosomal enzymes: (A) Signal sequence (B) Mannose-6-phosphate (C) Sialic acid (D) A serine residue

Last Answer : Answer : D

If a gene mutation prevents formation of an enzyme normally used by a lysosomes, a disease may result known as (A) Lysosomal abstracted disease (B) Lysosomal secretory disease (C) Lysosomal storage disease (D) All A, B and C

Description : If a gene mutation prevents formation of an enzyme normally used by a lysosomes, a disease may result known as (A) Lysosomal abstracted disease (B) Lysosomal secretory disease (C) Lysosomal storage disease (D) All A, B and C

Last Answer : (C) Lysosomal storage disease

Which of the following is present as a marker in lysosomal enzymes to direct them to their destination? (A) Glucose-6-phosphate (B) Mannose-6-phosphate (C) Galactose-6-phosphate (D) N-Acetyl neuraminic acid

Description : Which of the following is present as a marker in lysosomal enzymes to direct them to their destination? (A) Glucose-6-phosphate (B) Mannose-6-phosphate (C) Galactose-6-phosphate (D) N-Acetyl neuraminic acid

Last Answer : Answer : C

In cell, digestive enzymes are found mainly in (A) Vacuoles (B) Lysosomes (C) Ribosomes (D) Lomasomes

Description : In cell, digestive enzymes are found mainly in (A) Vacuoles (B) Lysosomes (C) Ribosomes (D) Lomasomes

Last Answer : Answer : B

Viropexis takes place in the phagocytic vacuoles and is due to the action of Enzymes A- DNA gyrase B- lysosomal protease C- lysosomal lipaseD- all of these

Description : Viropexis takes place in the phagocytic vacuoles and is due to the action of Enzymes A- DNA gyrase B- lysosomal protease C- lysosomal lipase D- all of these

Last Answer : lysosomal protease

TThe most important mechanism of antiinflammatory action of glucocorticoids is: A. Inhibition of lysosomal enzymes B. Restriction of recruitment of inflammatory cells at the site of inflammation C. Antagonism of action of interleukins D. Suppression of complement function

Description : The most important mechanism of antiinflammatory action of glucocorticoids is: A. Inhibition of lysosomal enzymes B. Restriction of recruitment of inflammatory cells at the site of inflammation C. Antagonism of action of interleukins D. Suppression of complement function

Last Answer : B. Restriction of recruitment of inflammatory cells at the site of inflammation

Tarui disease is characterized by the deficiency of the enzyme: (A) Liver phosphorylase (B) Muscle phosphorylase (C) Muscle and erythrocyte phosphofructokinase (D) Lysosomal acid maltase

Description : Tarui disease is characterized by the deficiency of the enzyme: (A) Liver phosphorylase (B) Muscle phosphorylase (C) Muscle and erythrocyte phosphofructokinase (D) Lysosomal acid maltase

Last Answer : Answer : C

Ribosomal RNA is actively synthesised in (a) lysosomes (b) nucleolus (c) nucleoplasm (d) ribosomes.

Description : Ribosomal RNA is actively synthesised in (a) lysosomes (b) nucleolus (c) nucleoplasm (d) ribosomes.

Last Answer : (a) lysosomes

Ribosomal RNA is actively synthesised in (a) lysosomes (b) nucleolus (c) nucleoplasm (d) ribosomes.

Description : Ribosomal RNA is actively synthesised in (a) lysosomes (b) nucleolus (c) nucleoplasm (d) ribosomes.

Last Answer : (b) nucleolus

The d igest ive enzymes of ce l lu lar compounds are confined to (A) Lysosomes (B) Ribosomes (C) Peroxisomes (D) Polysomes

Description : The d igest ive enzymes of ce l lu lar compounds are confined to (A) Lysosomes (B) Ribosomes (C) Peroxisomes (D) Polysomes

Last Answer : A

Enzymes catalyzing electron transport are present mainly in the (A) Ribosomes (B) Endoplasmic reticulum (C) Lysosomes (D) Inner mitochondrial membrane

Description : Enzymes catalyzing electron transport are present mainly in the (A) Ribosomes (B) Endoplasmic reticulum (C) Lysosomes (D) Inner mitochondrial membrane

Last Answer : D

Inactive precursors of enzymes are known as (A) Apoenzymes (B) Coenzymes (C) Proenzymes (D) Holoenzymes

Description : Inactive precursors of enzymes are known as (A) Apoenzymes (B) Coenzymes (C) Proenzymes (D) Holoenzymes

Last Answer : Answer : C

Enzymes, which are produced in inactive form in the living cells, are called (A) Papain (B) Lysozymes (C) Apoenzymes (D) Proenzymes

Description : Enzymes, which are produced in inactive form in the living cells, are called (A) Papain (B) Lysozymes (C) Apoenzymes (D) Proenzymes

Last Answer : Answer : D

Inactive zymogens are precursors of all the following gastrointestinal enzymes except (A) Carboxypeptidase (B) Pepsin (C) Amino peptidase (D) Chymotrypsin

Description : Inactive zymogens are precursors of all the following gastrointestinal enzymes except (A) Carboxypeptidase (B) Pepsin (C) Amino peptidase (D) Chymotrypsin

Last Answer : Answer : C

The site of enzymes directing the metabolic oxidation (respiration), ATP synthesis and considered as power house of cell are (A) Lysosomes (B) Microsomes (C) Mitochondria (D) Golgi apparatus

Description : The site of enzymes directing the metabolic oxidation (respiration), ATP synthesis and considered as power house of cell are (A) Lysosomes (B) Microsomes (C) Mitochondria (D) Golgi apparatus

Last Answer : (C) Mitochondria

Pompe ’s d isease is caused due to deficiency of (A) Lysosomal α-1→4 and 1→6-glucosidase (B) Glucose-6-phosphatase (C) Glycogen synthase (D) Phosphofructokinase

Description : Pompe ’s d isease is caused due to deficiency of (A) Lysosomal α-1→4 and 1→6-glucosidase (B) Glucose-6-phosphatase (C) Glycogen synthase (D) Phosphofructokinase

Last Answer : Answer : A

Humans cannot digest cellulose because: a) it does not contain sugars b) it is made up of disaccharides c) it is made up of monosaccharides d) humans lack the proper enzymes

Description : Humans cannot digest cellulose because: a) it does not contain sugars b) it is made up of disaccharides c) it is made up of monosaccharides d) humans lack the proper enzymes

Last Answer : ANSWER: D -- HUMANS LACK THE PROPER ENZYMES 

All the following statements about ceruloplasmin are correct except (A) It is a copper-containing protein (B) It possesses oxidase activity (C) It is synthesised in intestinal mucosa (D) Its plasma level is decreased inWilson’s disease

Description : All the following statements about ceruloplasmin are correct except (A) It is a copper-containing protein (B) It possesses oxidase activity (C) It is synthesised in intestinal mucosa (D) Its plasma level is decreased inWilson’s disease

Last Answer : Answer : C

All of the following statements about Tangier disease are true except (A) It is a disorder of HDL metabolism (B) Its inheritance is autosomal recessive (C) Apoproteins A-I and A-II are not synthesised (D) Plasma HDL is increased

Description : All of the following statements about Tangier disease are true except (A) It is a disorder of HDL metabolism (B) Its inheritance is autosomal recessive (C) Apoproteins A-I and A-II are not synthesised (D) Plasma HDL is increased

Last Answer : Answer : D

A person’s lysosomes lack the enzyme β-glucosidase ?

Description : There is an inherited disease in which a person’s lysosomes lack the enzyme β-glucosidase What are the clinical and biochemical consequences of this deficiency?

Last Answer : The disease is called Gaucher disease, and it is the most common of the sphingolipidoses; its incidence in the general population is ∼1:2500. This class of disease results from defective hydrolysis of ... may show signs of mental deterioration if much of the lipid accumulates in the brain as well. 

Which of the following best explains the existence of organized gangs of delinquent teenagers with which students often affiliate themselves? Options: A) Inactive and lax law enforcement B) Lack of parks and others facilities for amusement C) Lack of constructive activities from which students can derive wholesome satisfaction D) Student's desire for adventure

Description : Which of the following best explains the existence of organized gangs of delinquent teenagers with which students often affiliate themselves? Options: A) Inactive and lax law enforcement B) ... activities from which students can derive wholesome satisfaction D) Student's desire for adventure

Last Answer : C) Lack of constructive activities from which students can derive wholesome satisfaction

Which of the following organelles contain enzymes that have digestive action? (a) Ribosomes (b) Polysomes (c) Plastids (d) Lysosomes

Description : Which of the following organelles contain enzymes that have digestive action? (a) Ribosomes (b) Polysomes (c) Plastids (d) Lysosomes

Last Answer : (d) Lysosomes

Lysosomes are rich in (a) nucleic acids (b) hydrolytic enzymes (c) carbohydrates (d) hormones.

Description : Lysosomes are rich in (a) nucleic acids (b) hydrolytic enzymes (c) carbohydrates (d) hormones.

Last Answer : (b) hydrolytic enzymes

Select the alternative giving correct identification and function of the organelle ‘A’ in the diagram. (a) Mitochondria - Produce cellular energy in the form of ATP (b) Golgi body - Provides packaging material (c) Lysosomes - Secrete hydrolytic enzymes (d) Endoplasmic reticulum - Synthesis of lipids

Description : Select the alternative giving correct identification and function of the organelle A' in the diagram. (a) Mitochondria - Produce cellular energy in the form of ATP (b) Golgi body - ... packaging material (c) Lysosomes - Secrete hydrolytic enzymes (d) Endoplasmic reticulum - Synthesis of lipids

Last Answer : (a) Mitochondria - Produce cellular energy in the form of ATP

Which of the following statements is not correct? (a) Lysosomes are formed by the process of packaging in the endoplasmic reticulum. (b) Lysosomes have numerous hydrolytic enzymes. (c) The hydrolytic enzymes of lysosomes are active under acidic pH. (d) Lysosomes are membrane-bound structures.

Description : Which of the following statements is not correct? (a) Lysosomes are formed by the process of packaging in the endoplasmic reticulum. (b) Lysosomes have numerous hydrolytic enzymes. (c) The hydrolytic enzymes of lysosomes are active under acidic pH. (d) Lysosomes are membrane-bound structures.

Last Answer : (a) Lysosomes are formed by the process of packaging in the endoplasmic reticulum.

Acute pancreatitis is characterised by (A) Lack of synthesis of zymogen enzymes (B) Continuous release of zymogen enzymes into the gut (C) Premature activation of zymogen enzymes (D) Inactivation of zymogen enzymes

Description : Acute pancreatitis is characterised by (A) Lack of synthesis of zymogen enzymes (B) Continuous release of zymogen enzymes into the gut (C) Premature activation of zymogen enzymes (D) Inactivation of zymogen enzymes

Last Answer : Answer : C

The signal sequence of proteins is cleaved off (A) On the ribosomes immediately after synthesis (B) In the endoplasmic reticulum (C) During processing in Golgi apparatus (D) During passage through the cell membrane

Description : The signal sequence of proteins is cleaved off (A) On the ribosomes immediately after synthesis (B) In the endoplasmic reticulum (C) During processing in Golgi apparatus (D) During passage through the cell membrane

Last Answer : Answer : B

The proteins destined to be transported out of the cell have all the following features except (A) They possess a signal sequence (B) Ribosomes synthesizing them are bound to endoplasmic reticulum (C) After synthesis, they are delivered into Golgi apparatus (D) They are tagged with ubiquitin

Description : The proteins destined to be transported out of the cell have all the following features except (A) They possess a signal sequence (B) Ribosomes synthesizing them are bound to endoplasmic reticulum (C) After synthesis, they are delivered into Golgi apparatus (D) They are tagged with ubiquitin

Last Answer : Answer : D

Dietary fibre denotes (A) Undigested proteins (B) Plant cell components that cannot be digested by own enzymes (C) All plant cell wall components (D) All non digestible water insoluble polysaccharide

Description : Dietary fibre denotes (A) Undigested proteins (B) Plant cell components that cannot be digested by own enzymes (C) All plant cell wall components (D) All non digestible water insoluble polysaccharide

Last Answer : Answer : B

Chain elongation of fatty acids occurring in mammalian liver takes place in which of the following subcellular fractions of the cell? (A) Nucleus (B) Ribosomes (C) Lysosomes (D) Microsomes

Description : Chain elongation of fatty acids occurring in mammalian liver takes place in which of the following subcellular fractions of the cell? (A) Nucleus (B) Ribosomes (C) Lysosomes (D) Microsomes

Last Answer : Answer : D

The power house of the cell is (A) Nucleus (B) Cell membrane (C) Mitochondria (D) Lysosomes

Description : The power house of the cell is (A) Nucleus (B) Cell membrane (C) Mitochondria (D) Lysosomes

Last Answer : C

In the process of transcription in bacterial cells (A) Initiation requires rho protein (B) RNA polymerase incorporates methylated bases in correct sequence (C) Both the sigma unit and core enzymes of RNA polymerase are required for accurate promotor site binding (D) Primase is necessary for initiation

Description : In the process of transcription in bacterial cells (A) Initiation requires rho protein (B) RNA polymerase incorporates methylated bases in correct sequence (C) Both the sigma unit and core ... RNA polymerase are required for accurate promotor site binding (D) Primase is necessary for initiation

Last Answer : Answer : C

In the biosynthesis of cortiol, the sequence of enzymes involved is (A) Hydroxylase–dehydrogenase + isomerase – hydroxylase (B) Dehydrogenase–hydroxylase–isomerase (C) Hydroxylase–lyase–dehydrogenase isomerase (D) Isomerase–lyase–hydroxylase–dehydrogenase

Description : In the biosynthesis of cortiol, the sequence of enzymes involved is (A) Hydroxylase–dehydrogenase + isomerase – hydroxylase (B) Dehydrogenase–hydroxylase–isomerase (C) Hydroxylase–lyase–dehydrogenase isomerase (D) Isomerase–lyase–hydroxylase–dehydrogenase

Last Answer : Answer : A

Androgens are synthesised in (A) Leydig cells in testes (B) Sertoli cells in testes (C) Seminiferous tubules (D) Prostate gland

Description : Androgens are synthesised in (A) Leydig cells in testes (B) Sertoli cells in testes (C) Seminiferous tubules (D) Prostate gland

Last Answer : Answer : A

All the following statements about transcortin are true except (A) It is synthesised in liver (B) It transports glucocorticoids (C) It transports aldosterone (D) It transports progesterone

Description : All the following statements about transcortin are true except (A) It is synthesised in liver (B) It transports glucocorticoids (C) It transports aldosterone (D) It transports progesterone

Last Answer : Answer : C

Steroid hormones are synthesised from (A) Cholesterol (B) 7-Dehydrocholesterol (C) Calcitriol (D) 7-Hydroxycholesterol

Description : Steroid hormones are synthesised from (A) Cholesterol (B) 7-Dehydrocholesterol (C) Calcitriol (D) 7-Hydroxycholesterol

Last Answer : Answer : A

Steroid hormones are synthesised in all of the following except (A) Testes (B) Ovaries (C) Adrenal medulla (D) Adrenal cortex

Description : Steroid hormones are synthesised in all of the following except (A) Testes (B) Ovaries (C) Adrenal medulla (D) Adrenal cortex

Last Answer : Answer : A

Epinephrine is synthesised in (A) Chromaffin cells of adrenal medulla (B) Sympathetic ganglia (C) Brain (D) All of these

Description : Epinephrine is synthesised in (A) Chromaffin cells of adrenal medulla (B) Sympathetic ganglia (C) Brain (D) All of these

Last Answer : Answer : D

Dopamine is synthesised from (A) Dihydroxyphenylalanine (B) Epinephrine (C) Norepinephrine (D) Metanephrine

Description : Dopamine is synthesised from (A) Dihydroxyphenylalanine (B) Epinephrine (C) Norepinephrine (D) Metanephrine

Last Answer : Answer : A

Parathyroid hormone (PTH) is synthesised in (A) Chief cells of parathyroid glands (B) Oxyphil cells of parathyroid glands (C) Para follicular cells of thyroid glands (D) Follicular cells of thyroid gland

Description : Parathyroid hormone (PTH) is synthesised in (A) Chief cells of parathyroid glands (B) Oxyphil cells of parathyroid glands (C) Para follicular cells of thyroid glands (D) Follicular cells of thyroid gland

Last Answer : Answer : A

All the following statements about proopiomelanocortin are true except (A) It is made up of 285 amino acids (B) It is synthesised in pars intermedia and anterior lobe of pituitary gland (C) It is the precursor of ACTH and melatonin (D) It is the precursor of corticotropin like intermediate lobe peptide and endorphins 218 MCQs IN BIOCHEMISTRY

Description : All the following statements about proopiomelanocortin are true except (A) It is made up of 285 amino acids (B) It is synthesised in pars intermedia and anterior lobe of pituitary gland ... ) It is the precursor of corticotropin like intermediate lobe peptide and endorphins 218 MCQs IN BIOCHEMISTRY

Last Answer : Answer : C

A hormone synthesised in the hypothalamus is (A) Melatonin (B) Melanocyte stimulating hormone (C) Vasopressin (D) Prolactin

Description : A hormone synthesised in the hypothalamus is (A) Melatonin (B) Melanocyte stimulating hormone (C) Vasopressin (D) Prolactin

Last Answer : Answer : C

Melatonin is synthesised from (A) Phenylalanine (B) Tyrosine (C) Tryptophan (D) None of these

Description : Melatonin is synthesised from (A) Phenylalanine (B) Tyrosine (C) Tryptophan (D) None of these

Last Answer : Answer : C

Melatonin is synthesised in (A) Hypothalamus (B) Posterior pituitary gland (C) Pineal gland (D) Melanocytes

Description : Melatonin is synthesised in (A) Hypothalamus (B) Posterior pituitary gland (C) Pineal gland (D) Melanocytes

Last Answer : Answer : C

Niacin can be synthesised in human beings from (A) Histidine (B) Phenylalanine (C) Tyrosine (D) Tryptophan

Description : Niacin can be synthesised in human beings from (A) Histidine (B) Phenylalanine (C) Tyrosine (D) Tryptophan

Last Answer : Answer : D

Prothrombin is synthesised in (A) Erythrocytes (B) Reticulo-endothelial cells (C) Liver (D) Kidneys

Description : Prothrombin is synthesised in (A) Erythrocytes (B) Reticulo-endothelial cells (C) Liver (D) Kidneys

Last Answer : Answer : C

All the following statements about carnitine are true except (A) It can be synthesised in the human body (B) It can be synthesized from methionine and lysine (C) It is required for transport of short chain fatty acids into mitochondria (D) Its deficiency can occur due to haemodialysis

Description : All the following statements about carnitine are true except (A) It can be synthesised in the human body (B) It can be synthesized from methionine and lysine (C) It is required for transport of short chain fatty acids into mitochondria (D) Its deficiency can occur due to haemodialysis

Last Answer : Answer : C

Serotonin is synthesised from (A) Serine (B) Phenylalanine (C) Tyrosine (D) Tryptophan

Description : Serotonin is synthesised from (A) Serine (B) Phenylalanine (C) Tyrosine (D) Tryptophan

Last Answer : Answer : D

Histamine is synthesised in (A) Brain (B) Mast cells (C) Basophils (D) All of these

Description : Histamine is synthesised in (A) Brain (B) Mast cells (C) Basophils (D) All of these

Last Answer : Answer : D

Calcitonin is synthesised in (A) Parathyroid glands (B) Thyroid gland (C) Pars intermedia of pituitary (D) Adrenal cortex

Description : Calcitonin is synthesised in (A) Parathyroid glands (B) Thyroid gland (C) Pars intermedia of pituitary (D) Adrenal cortex

Last Answer : Answer : B