Description : Lysolecithin is formed from lecithin by the action of (A) Phospholipase A1 (B) Phospholipase A2 (C) Phospholipase C (D) Phospholipase D
Last Answer : Answer : B
Description : Lysolecithin is formed from lecithin by removal of (A) Fatty acid from position 1 (B) Fatty acid from position 2 (C) Phosphorylcholine (D) Choline
Description : When choline of lecithin is replaced by ethanolamine, the product is (A) Spingomyelin (B) Cephalin (C) Plasmalogens (D) Lysolecithin
Description : Which of the following is not a phospholipids? (A) Lecithin (B) Plasmalogen (C) Lysolecithin (D) Gangliosides
Last Answer : Answer : D
Description : Which one of the following is not a phospholipid? (A) Lecithin (B) Plasmalogen (C) Lysolecithin (D) Gangliosides
Description : Non steroidal anti inflammatory drugs, such as aspirin act by inhibiting the activity of the enzyme: (A) Lipoxygenase (B) Cyclooxygenase (C) Phospholipase A2 (D) Lipoprotein lipase
Description : A ’suicide enzyme’ is (A) Cycloxygenase (B) Lipooxygenase (C) Phospholipase A1 (D) Phospholipase A2
Last Answer : Answer : A
Description : Aspirin inhibits the activity of the enzyme: (A) Lipoxygenase (B) Cyclooxygenase (C) Phospholipae A1 (D) Phospholipase A2
Description : Which one of the following biomolecules is correctly characterized? (a) Lecithin-a phosphorylated glyceride found in cell membrane. (b) Palmitic acid - an unsaturated fatty acid with 18 carbon atoms. ... Alanine amino acid - contains an amino group and an acidic group anywhere in the molecule.
Last Answer : (a) Lecithin-a phosphorylated glyceride found in cell membrane
Description : Apolipoprotein C-II is an activator of (A) Lecithin cholesterola acyl transferase (B) Phospholipase C (C) Extrahepatic lipoprotein lipase (D) Hepatic lipoprotein lipase
Last Answer : Answer : C
Description : Anti-inflammatory corticosteroids inhibit (A) Phospholipase A1 (B) Phospholipase A2 (C) Cyclo-oxygenase (D) Lipo-oxygenase
Description : Phenylbutazone and indomethacin inhibit (A) Phospholipase A1 (B) Phospholipase A2 (C) Cyclo-oxygenase (D) Lipo-oxygenase
Description : Inflammation is a complex tissue reaction that includes the release of cytokines, leukotrienes, prostaglandins, and peptides. Prostaglandins involved in inflammatory processes are produced from arachidonic acid by (a) ... 2 (c) Glutathione - S - transferase (d) Lipoxygenase (e) Phospholipase A2
Last Answer : Ans: B
Description : Platelet activating factor is: a. Generated by the action of phospholipase A2 on membrane phospholipids b. Antiinflammatory in most of its actions c. Synthesized by endothelial and other cells d. Exerts a variety of biologic effects which are platelet-independent
Last Answer : Answer: a, c, d Like the eicosanoids, platelet-activating factor (PAF) is not stored in cells but is rapidly produced during inflammation. PAF exerts a variety of biologic effects ... and LTB4. There is considerable overlap and redundancy in the effects produced by PAF and eicosanoids
Description : a2–adrenergic receptors are associated with following except (a) Increase in phospholipase C activity (b) Increase in potassium channel conductance (c) Decrease in calcium channel conductance (d) Increase in adenylyl cyclase activity
Last Answer : Ans: D
Description : The mechanism of action of cyclosporine involves (a) Activation of calcineurin (b) Binding to cyclophilin to cause inhibition of a cytoplasmic phosphatase (c) Blockade of interleukin – 2- receptors (d) Inhibition of phospholipase A2 (e) Suppression of bone marrow progenitors
Description : I-cell disease results from absence of the following from lysosomal enzymes: (A) Signal sequence (B) Mannose-6-phosphate (C) Sialic acid (D) A serine residue
Description : Vitamin K is a cofactor for (A) Gamma carboxylation of glutamic acid residue (B) β-Oxidation of fatty acid (C) Formation of γ-amino butyrate (D) Synthesis of tryptophan
Description : Synthesis of polyunsaturated fatty acids involves the enzyme systems: (A) Acyl transferase and hydratase (B) Desaturase and elongase (C) Ketoacyl-CoA reductase and hydratase (D) Dihydroxyacetone phosphate
Description : Dolichol phosphate is A- a complex lipid involved in docking vesicles with the plasma membrane B- the anchor on which sugars assemble before transfer to proteins C- a chaperone used in protein folding D- a product of phospholipase C activation
Last Answer : the anchor on which sugars assemble before transfer to proteins
Description : Oils and fats are (a) Glyceryl esters of higher fatty acids (b) Acetyl esters of higher fatty acids (c) Ethyl esters of fatty acids (d) Methyl esters of fatty acids
Last Answer : Ans:(a)
Description : Intermediate in the denovo synthesis of triacyl glycerols include all the following except (A) Fatty acyl CoA (B) CDP diacyl glycerol (C) Glycerol-3-phosphate (D) Lysophosphatidic acid
Description : Covalent modification of an enzyme usually involves phosphorylation / dephosphorylation of (A) Serine residue (B) Proline residue (C) Hydroxylysine residue (D) Hydroxyproline residue
Description : Sphingomyelins contain a complex amino alcohol named as (A) Serine (B) Lysolecithin (C) Sphingosine (D) Glycol
Description : Corticosteroids exert anti-inflammatory action by inhibiting the following enzyme (a) Cycloxygenase (b) Lipozygenase (c) Phospholipase - A (d) Phosphodiesterase
Last Answer : Ans: C
Description : Corticosteroids exert antiinflammatory action by inhibiting the following enzyme: A. Cyclooxygenase B. Lipoxygenase C. Phospholipase-A D. Phosphodiesterase
Last Answer : C. Phospholipase-A
Description : A substrate for the enzyme aldolase is (A) galactose-6-phosphate (B) isocitric acid (C) Glucose-1-phosphate (D) Fructose 1, 6 diphosphate
Description : The transketolase enzyme in the pentose phosphate pathway requires the B vitamin. (A) Pantothenic acid (B) Thiamin (C) Riboflavin (D) Nicotinic acid
Description : The enzyme regulating extramitochondrial fatty acid synthesis is (A) Thioesterase (B) Acetyl CoA carboxylase (C) Acyl transferase (D) Multi-enzyme complex
Description : The protein, which is in fact a multifunctional enzyme complex in higher organism is (A) Acetyl transacylase (B) Malonyl transacylase (C) 3-Hydroxy acyl-ACP dehyratase (D) Fatty acid synthase
Description : Human desaturase enzyme system cannot introduce a double bond in a fatty acid beyond (A) Carbon 9 (B) Carbon 6 (C) Carbon 5 (D) Carbon 3
Description : One functional sub-unit of multi-enzyme complex for de novo synthesis of fatty acids contains (A) One —SH group (B) Two —SH groups (C) Three —SH groups (D) Four —SH groups FATS AND FATTY ACID METABOLISM 87
Description : The enzyme acyl-CoA synthase catalyses the conversion of a fatty acid of an active fatty acid in the presence of (A) AMP (B) ADP (C) ATP (D) GTP
Description : Acetyl CoA from mitochondria is transferred to cytoplasm for the de novo synthesis of fatty acid, by which enzyme?
Last Answer : ATP citrate lyase.
Description : What is the rate limiting enzyme of de novo synthesis of fatty acid?
Last Answer : Acetyl CoA carboxylase.
Description : Fatty acids can not be converted into carbohydrates in the body, as the following reaction is not possible: (A) Conversion of glucose-6-phosphate into glucose (B) Fructose 1, 6 diphosphate to ... phosphate (C) Transformation of acetyl CoA to pyruvate (D) Formation of acetyl CoA from fatty acids
Description : Fatty acids cannot be converted into carbohydrates in the body as the following reaction is not possible. (A) Conversion of glucose-6-phosphate into glucose (B) Fructose 1,6-bisphosphate to fructose- ... (C) Transformation of acetyl CoA to pyruvate (D) Formation of acetyl CoA from fatty acids
Last Answer : C
Description : LCAT is (A) Lactose choline alamine transferse (B) Lecithin cholesterol acyl transferase (C) Lecithin carnitine acyl transferase (D) Lanoleate carbamoyl acyl transferase
Description : Lecithin contains a nitrogenous base named as (A) Ethanolamine (B) Choline (C) Inositol (D) All of these
Description : Activated lecithin cholesterol acyl transferase is essential for the conversion of (A) VLDL remnants into LDL (B) Nascent HDL into HDL (C) HDL2 into HDL3 (D) HDL3 into HDL2
Description : Dipalmitoyl lecithin acts as (A) Platelet activating factor (B) Second messenger for hormones (C) Lung surfactant (D) Anti-ketogenic compound
Description : The nitrogenous base in lecithin is (A) Ethanolamine (B) Choline (C) Serine (D) Betaine
Description : Phospholipid acting as surfactant is (A) Cephalin (B) Phosphatidyl inositol (C) Lecithin (D) Phosphatidyl serine
Description : What is Lecithin?
Last Answer : Phosphatidyl choline.
Description : A phosphoglyceride is always made up of (a) a saturated or unsaturated fatty acid esterified to a glycerol molecule to which a phosphate group is also attached (b) a saturated or unsaturated ... unsaturated fatty acid esterified to a glycerol molecule to which a phosphate group is also attached.
Last Answer : (a) a saturated or unsaturated fatty acid esterified to a glycerol molecule to which a phosphate group is also attached
Description : Which of the following statements is not true about phospholipids? (a) They are similar to triacylglycerols except that the middle OH group of glycerol reacts with a phosphate rather than with a ... is a phospholipid. (d) The C-2 carbon of glycerol in phosphoacylglycerols has the R configuration
Last Answer : They are similar to triacylglycerols except that the middle OH group of glycerol reacts with a phosphate rather than with a fatty acid
Description : Hydrocortisone induces the synthesis of the following protein which in turn inhibits the enzyme phospholipase-A2: A. Heat shock protein-90 B. Inhibin C. Transcortin D. Lipocortin
Last Answer : D. Lipocortin
Description : Phospholipase C is activated by (A) Gs proteins (B) Gi proteins (C) Gq proteins (D) G12 proteins
Description : Activated phospholipase C acts on (A) Phosphatidyl inositol-4, 5-biphosphate (B) Inositol-1, 4, 5-triphosphate (C) Protein kinase C (D) Pl-3 kinase
Description : Binding of insulin to its receptor activates (A) Adenylate cyclase (B) Guanylate cyclase (C) Phospholipase C (D) Tyrosine kinase