Description : A pathway that requires NADPH as a cofactor is (A) Fatty acid oxidation (B) Extra mitochondrial denovo fatty acid synthesis (C) Ketone bodies formation (D) Glycogenesis
Last Answer : Answer : B
Description : Synthesis of sphingosine requires the cofactor (A) NAD (B) NADP (C) NADPH+ (D) ATP
Last Answer : Answer : C
Description : A cofactor required for the conversion of acetyl-CoA to malonyl-CoA in extramitochondrial fatty acid synthesis is (A) Biotin (B) FMN (C) NAD (D) NADP
Last Answer : Answer : A
Description : NADPH required for fatty acid synthesis can come from (A) Hexose monophosphate shunt (B) Oxidative decarboxylation of malate (C) Extramitochondrial oxidation of isocitrate (D) All of these
Last Answer : Answer : D
Description : Glucocorticoids increase all of the following except (A) Gluconeogenesis (B) Lipolysis in extremities (C) Synthesis of elcosanoida (D) Hepatic glycogenesis
Description : Synthesis of Glucose from amino acids is termed as (A) Glycolysis (B) Gluconeogenesis (C) Glycogenesis (D) Lipogenesis
Last Answer : B
Description : For reduction enzyme HMG-CoA reductase requires cofactor: (A) NADPH (B) NADP (C) NAD (D) FAD
Description : An important reaction for the synthesis of amino acid from carbohydrate intermediates is transamination which requires the cofactor: (A) Thiamin (B) Riboflavin (C) Niacin (D) Pyridoxal phosphat
Description : Pentose phosphate pathway is of significance because it generates (A) NADPH for reductive synthesis (B) Regenerates glucose 6-phosphate (C) Generates fructose 6-phosphate (D) Forms glyceraldehyde 3-phosphate
Description : Vitamin K is a cofactor for (A) Gamma carboxylation of glutamic acid residue (B) β-Oxidation of fatty acid (C) Formation of γ-amino butyrate (D) Synthesis of tryptophan
Description : Epinephrine causes in muscle: (A) Gluconeogenesis (B) Glycogenesis (C) Glycolysis (D) Glycogenolysis
Description : Excessive secretion of glucocorticoids raises blood glucose by (A) Decreasing glycogenesis (B) Increasing glycogenolysis (C) Increasing gluconeogenesis (D) Inhibiting HMP shunt
Description : Epinephrine decreases (A) Glycogenesis (B) Glycogenolysis (C) Gluconeogenesis (D) Lipolysis
Description : Insulin increases (A) Glycogenesis (B) Gluconeogenesis (C) Lipolysis (D) Blood glucose
Description : Insulin decreases (A) Glycogenesis (B) Glyolysis (C) Gluconeogenesis (D) Tubular reabsorption of glucose
Description : Insulin stimulates (A) Hepatic glycogenolysis (B) Hepatic glycogenesis (C) Lipolysis (D) Gluconeogenesis
Description : Conversion of Alanine to carbohydrate is termed: (A) Glycogenesis (B) Gluconeogenesis (C) Glycogenolysis (D) Photosynthesis
Description : All the enzymes of glycolysis pathway are found in (A) Extramitochondrial soluble fraction of the cell (B) Mitochondria (C) Nucleus (D) Endoplasmic reticulum
Description : Epinephrine increases the concentration of free fatty acids in plasma by increasing (A) Extramitochondrial fatty acid synthesis (B) Mitochondrial fatty acid chain elongation (C) Microsomal fatty acid chain elongation (D) Lipolysis in adipose tissue
Description : The enzyme regulating extramitochondrial fatty acid synthesis is (A) Thioesterase (B) Acetyl CoA carboxylase (C) Acyl transferase (D) Multi-enzyme complex
Description : Which of the following cofactors or their derivatives must be present for the conversion of acetyl CoA to malonyl CoA extramitochondrial fatty acid synthesis? (A) Biotin (B) FAD (C) FMN (D) ACP
Description : For extramitochondrial fatty acid synthesis, acetyl CoA may be obtained from (A) Citrate (B) Isocitrate (C) Oxaloacetate (D) Succinate
Description : The synthesis of glucose from pyruvate by gluconeogenesis (A) Requires the participation of biotin (B) Occurs exclusively in the cytosol (C) Is inhibited by elevated level of insulin (D) Requires oxidation/reduction of FAD
Last Answer : A
Description : Most of the metabolic pathways are either anabolic or catabolic. Which of the following pathways is considered as “amphibolic” in nature? (A) Glycogenesis (B) Glycolytic pathway (C) Lipolysis (D) TCA cycle
Last Answer : D
Description : The main source of reducing equivalents (NADPH) for lipogenesis is (A) Pentose phosphate pathway (B) Citric acid cycle (C) Glycolysis (D) Glycogenolysis
Description : Most major metabolic pathways are considered mainly either anabolic or catabolic. Which of the following pathway is most correctly considered to be amphibolic? (A) Citric acid cycle (B) Gluconeogenesis (C) Lipolysis (D) Glycolysis
Description : An amphibolic pathway among the following is (A) HMP shunt (B) Glycolysis (C) Citirc acid cycle (D) Gluconeogenesis
Last Answer : C
Description : A soluble system for synthesis of fatty acids have been isolated from avian liver, required for the formation of long chain fatty acids by this system is (A) ATP (B) Acetyl CoA (C) NADPH (D) All of these
Description : Which of the following products of triacylglycerol breakdown and subsequent β-Oxidation may undergo gluconeogenesis? (A) Acetyl CoA (B) Porpionyl CoA (C) All ketone bodies (D) Some amino acids
Description : Extramitochondrial synthesis of fatty acids occurs in (A) Mammary glands (B) Lungs (C) Brain (D) All of these
Description : Apart from NADPH generation, is there any other purpose for the HMPshunt pathway?
Last Answer : The pathway is required for the synthesis of ribose, the pentose phosphates are necessary for nucleotide (DNA and RNA) synthesis.
Description : Glycogenesis requires (A) GTP (B) CTP (C) UTP (D) None of these
Description : Conversion of retinal into ritonal requires the presence of (A) NADH (B) NADPH (C) FADH2 (D) Lipoic acid
Description : Which of the following is required as a reductant in fatty acid synthesis? (A) NADH (B) NADPH (C) FADH2 (D) FMNH2
Description : What are the sources of NADPH for fatty acid synthesis?
Last Answer : Glucose-6-phosphate dehydrogenase, malic enzyme, cytoplasmic malate dehydrogenase.
Description : What are the steps in which NADPH is used in fatty acid synthesis?
Last Answer : Step 4 (Keto acyl reductase) and Step 6 (Enoyl reductase).
Description : Reverse of Glycolysis is _________________. a. Glycogenolysis. b. Citric Acid Cycle. c. Gluconeogenesis. d. Uronic Acid Pathway
Last Answer : c. Gluconeogenesis.
Description : For the activation of long chain fatty acids the enzyme thiokinase requires the cofactor: (A) Mg++ (B) Ca++ (C) Mn++ (D) K+
Description : Infant i le convu ls ions due to lesser formation of gamma amino butyric acid from glutamic acid is seen in the deficiency of (A) Glutamate-dehydrogenase (B) Pyridoxine (C) Folic acid (D) Thiamin
Description : Conversion of uridine diphosphate into deoxyuridine diphosphate requires all the following except (A) Ribonucleotide reductase (B) Thioredoxin (C) Tetrahydrobiopterin (D) NADPH
Description : Thyroproxidase requires hydrogen peroxide as oxidizing agent. The H2O2 is produced by (A) FADH2 dependent enzyme (B) NADH dependent enzyme (C) NADP dependent enzyme (D) NADPH dependent enzyme
Description : Conversion of all-trans-retinal into alltrans-retinol requires (A) NAD (B) NADH (C) NADP (D) NADPH
Description : Conversion of folate into tetrahydrofolate requires (A) NADH (B) NADPH (C) FMNH2 (D) FADH2
Description : Mitochondrial lipogenesis requires (A) bicarbonate (B) biotin (C) acetyl CoA carboxylase (D) NADPH
Description : The transketolase enzyme in the pentose phosphate pathway requires the B vitamin. (A) Pantothenic acid (B) Thiamin (C) Riboflavin (D) Nicotinic acid
Description : Enzymes responsible for ketone body formation are associated mainly with the (A) Mitochondria (B) Endoplasmic reticulum (C) Nucleus (D) Golgi apparatus
Description : What is the rate-limiting-step in ketone body formation?
Last Answer : HMGCoA synthase.
Description : One of the main functions of Vitamin K is the cofactor for (A) Carboxylase for the formation of γ--carboxy glutamate (B) Methylation by S-adenosyl methionine (C) Carboxylation by biotin (D) One carbon transfer by tetra hydrofolate
Description : One of the main functions of Vitamin K is cofactor for (A) Carboxylate for the formation of γ carboxyglutamate (B) Methylation of δ-adenosyl methionine (C) Carboxylation of biotin (D) One carbon transfer by tetrahydrofolate
Description : The enzymes of the citric acid cycle are located in (A) Mitochondrial matrix (B) Extramitochondrial soluble fraction of the cell (C) Nucleus (D) Endoplasmic reticulum