Description : In essential pentosuria, urine contains (A) D-Ribose (B) D-Xylulose (C) L-Xylulose (D) D-Xylose
Last Answer : C
Description : The first pentose formed in HMP shunt is (A) Ribose-5-phosphate (B) Ribulose-5-phosphate (C) Xylose-5-phosphate (D)Xylulose-5-phosphate
Last Answer : Answer : B
Description : Xylulose-5-phosphate serves as a donar of active glycolaldehyde, the acceptor is (A) Erythrose 4-phosphate (B) Ribose 5-phosphate (C) Glyceraldehyde 3-phosphate (D) Sedoheptulose 7-phosphate
Last Answer : Answer : A
Description : For conjugation with many enogenous and exogenous substances before elimination in urine, the uronic acid pathway provides (A) Active glucuronate (B) Gulonate (C) Xylulose (D) Xylitol
Description : The 5- carbon compounds produced during dark reaction of photosynthesis is (A) Ribose phosphate (B) Xylulose phosphate (C) Ribulose bis phosphate (D) Seda heptulose phosphate
Last Answer : (C) Ribulose bis phosphate
Description : A 53-year-old man presented with hypertension of 150/110 mmHg. He is generally asymptomatic and has no previous medical history of note. He is a smoker of 5 cigarettes daily and drinks ... Adrenocortical adenoma 2) Bartter's syndrome 3) Liddle's syndrome 4) Liquorice ingestion 5) Pheochromocytoma
Last Answer : Answers-1 This patient is most likely to have Conn's syndrome as reflected by the hypokalaemic hypertension. Liquorice ingestion or Liddle's syndrome are again possible causes of ... hypertension (often diastolic hypertension), muscular weakness, paresthesias, headache, polyuria, and polydipsia."
Description : Increased urinary excretion of orotic acid can occur in deficiency of (A) Orotate phosphoribosyl transferase (B) OMP decarboxylase (C) Mitochondrial ornithine transcarbamoylase (D) Any of the above
Last Answer : Answer : D
Description : Urinary excretion of vanillyl madelic acid is increased in (A) Phaeochromocytoma (B) Cushing’s syndrome (C) Carcinoid syndrome (D) Aldosteronism
Description : Folic acid deficiency can be diagnosed by increased urinary excretion of (A) Methylmalonate (B) Figlu (C) Cystathionine (D) Creatinine
Description : All the following are true about phenylketonuria except (A) Deficiency of phenylalanine hydroxylase (B) Mental retardation (C) Increased urinary excretion of p-hydroxyphenyl pyruvic acid (D) Decrease serotonin formation
Last Answer : Answer : C
Description : All the following statements about phenylketonuria are correct except (A) Phenylalanine cannot be converted into tyrosine (B) Urinary excretion of phenylpyruvate and phenyllactate is increased (C) It ... diet (D) It leads to decreased synthesis of thyroid hormones, catecholamines and melanin
Description : In case of wilson’s disease, the features include all of the following except (A) Progressive hepatic cirrhosis (B) Keyser Fleisher ring (C) Aminoaciduria (D) Urinary excretion of Cu is decreased
Description : The four membered aldose sugar phosphate formed in HMP shunt pathway is (A) Xylulose P (B) Erythrulose P (C) Erythrose P (D) Ribulose P
Description : A 55 year-old female complaining of vague tiredness is found to have a serum corrected calcium concentration of 2.9 mmol/l. Examination was unremarkable. Which of the following results ... 4) Low normal plasma phosphate concentration 5) Low normal serum 25-hydroxyvitamin D concentration
Last Answer : Answers-3 Bit too easy really. A high or even normal PTH concentration in the presence of hypercalcaemia would support the diagnosis of hyperparathyroidism. A high urinary Calcium concentration may ... but neither confirm the diagnosis. Elevated 1,25 VitD suggests a diagnosis of hypervitaminosis D.
Description : Which of the following statements regarding hypercalcemia are true? A. The symptoms of hypercalcemia may mimic some symptoms of hyperglycemia. B. Metastatic breast cancer is an unusual cause of ... fluid volume deficit. E. Urinary calcium excretion may be increased by vigorous volume repletion.
Last Answer : Answer: ADE DISCUSSION: Markedly elevated serum calcium levels produce polydipsia, polyuria, and thirst. Vigorous volume repletion and saline diuresis correct the extracellular fluid volume ... , from bony metastasis. The calcitonin effect on calcium is diminished with repeat administrations
Description : Hepatocellular jaundice as compared to pure obstructive type of jaundice is characterized by (A) Increased serum alkaline phosphate, LDH and ALT (B) Decreased serum alkaline phosphatase, LDH and ALT (C ... levels of LDH and ALT (D) Decreased serum alkaline phosphatase and increased serum LDH and ALT
Description : An L-isomer of monosaccharide formed in human body is (A) L-fructose (B) L-Erythrose (C) L-Xylose (D) L-Xylulose
Last Answer : D
Description : A key substance in the committed step of pyrimidines biosynthesis is (A) Ribose-5-phosphate (B) Carbamoyl phosphate (C) ATP (D) Glutamine
Description : A common substrate of HGPRTase, APRTase and PRPP glutamyl amidotransferase is (A) Ribose 5 phosphate (B) Phosphoribosyl pyrophosphate (C) Hypoxanthine (D) Adenosine
Description : 6-Mercapto purine inhibits the conversion of (A) IMP→ XMP (B) Ribose 5 phosphate → PRPP (C) PRPP → 5-phospho →β -D-ribosylamine (D) Glycinamide ribosyl 5-phosphate → formylglycinamide ribosyl-5-phosphate
Description : The key substance in the synthesis of purine, phosphoribosyl pyrophosphate is formed by (A) α-D-ribose 5-phosphate (B) 5-phospho β-D-ribosylamine (C) D-ribose (D) Deoxyribose
Description : Glucose-6-phosphate dehydrogenase is induced by (A) 6-Phosphogluconolactone (B) Glucose-6-phosphate (C) Ribose-5-phosphate (D) Insulin
Description : In pentose phosphate pathway, D-ribulose5-phosphate is converted to D-ribose-5- phosphate by the enzyme: (A) Fumarase (B) Ketoisomerase (C) G-6-PD (D) Epimerase
Description : In RNA, apart from ribose and phosphate, all following are present except (A) Adenine (B) Guanine (C) Thymine (D) Cytosine
Description : Daily urinary urobilinogen excretion in adult men is (A) 0–4 mg (B) 5–8 mg (C) 9–12 mg (D) 13–20 mg
Description : Which of the following is a characteristic feature of acute intermittent porphyria? 1) autosomal recessive inheritance 2) excessive faecal protoporphyrin excretion 3) excessive urinary porphobilinigoen between acute attacks 4) hypernatraemia during attacks 5) photosensitivity
Last Answer : Answers-3 Features of acute intermittent porphyria include urinary porphobilinogen excretion raised between attacks, hyponatraemia during an acute attack and autosomal dominant inheritance.
Description : All of the following statements about allopurinol are true except (A) It is a structural analogue of uric acid (B) It can prevent uric acid stones in the kidneys (C) It increases the urinary excretion of xanthine and hypoxanthine (D) It is a competitive inhibitor of xanthine oxidase
Description : All of the following statements about primary gout are true except (A) Uric acid stones may be formed in kidneys (B) Arthritis of small joints occurs commonly (C) Urinary excretion of uric acid is decreased (D) It occurs predominantly in males
Description : A characteristic of pheochromocytoma is elevated urinary excretion of (A) Dopamine (B) Tyrosine (C) Vinylmandelic acid (D) Phenylalanine
Description : A biochemical indication of vitamin B12 deficiency can be obtained by measuring the urinary excretion of (A) Pyruvic acid (B) Malic acid (C) Methyl malonic acid (D) Urocanic acid
Description : Laboratory diagnosis of vitamin B12 deficiency can be made by measuring the urinary excretion of (A) Xanthurenic acid (B) Formiminoglutamic acid (C) Methylmalonic acid (D) Homogentisic acid
Description : Pyridoxine deficiency can be diagnosed by measuring the urinary excretion of xanthurenic acid following a test dose of (A) Glycine (B) Histidine (C) Tryptophan (D) Pyridoxine
Description : Pyridoxine deficiency can be diagnosed by measuring urinary excretion of (A) Pyruvic acid (B) Oxaloacetic acid (C) Xanthurenic acid (D) None of these VITAMINS 119
Description : Vitamin B12 deficiency can be diagnosed by urinary excretion of (A) Pyruvate (B) Methylmalonate (C) Malate (D) Lactate
Description : In glycinuria daily urinary excretion of glycine ranges from (A) 100–200 mg (B) 300–500 mg (C) 600–1000 mg (D) 1100–1400 mg
Description : Which of the following diseases is a rare, transmissible, progressive fatal disease of the central nervous system characterized by spongiform degeneration of the gray matter of the brain? a) ... disease of the nervous system that results in progressive involuntary dance-like movement and dementia.
Last Answer : a) Creutzfeldt-Jakob’s disease The disease causes severe dementia and myoclonus.
Description : Increased urinary indole acetic acid is diagnostic of (A) Maple syrup urine disease (B) Hartnup disease (C) Homocystinuia (D) Phenylketonuria
Description : The enzyme involved in essential pentosuria is (A) Reductase (B) Hydroxylase (C) Isomerase (D) Racemase
Description : What is essential pentosuria?
Last Answer : Excretion of pentose (L-xylulose) in urine due to the deficiency of xylitol dehydrogenase.
Description : Characteristics of Vitamin D and its metabolites include which one of the following? (a) Act to decrease serum levels of calcium (b) Activation of their Vitamin D receptors increases cellular CAMP ... Vitamin D increase renal excretion of calcium (e) Vitamin D deficiency results in Pager's disease
Last Answer : Ans: C
Description : The sugar absorbed by fac i l itated diffusion and requiring Na independent transporter is (A) Glucose (B) Fructose (C) Galactose (D) Ribose
Description : Human heart muscle contains (A) D-Arabinose (B) D-Ribose (C) D-Xylose (D) L-Xylose
Description : PTH (A) Reduces the renal clearance or excretion of calcium (B) Increases renal phosphate clearance (C) Increases the renal clearance of calcium (D) Decreases the renal phosphate clearance
Description : Insulin degradation of disulfide bond formation is effected by (A) Pyruvate dehydrogenase (B) Xylitol reductase (C) Gutathione reductase (D) Xanthine oxidase
Description : Which one of the following is a non - reducing carbohydrate? (a) Maltose (b) Sucrose (c) Lactose (d) Ribose 5-phosphate
Last Answer : (b) Sucrose
Description : Of the following terms, which describes a condition characterized by abnormal spongy bone formation around the stapes? a) Otosclerosis Otosclerosis is more common in females than males and is ... perforation. d) Otitis externa Otitis externa refers to inflammation of the external auditory canal.
Last Answer : a) Otosclerosis Otosclerosis is more common in females than males and is frequently hereditary.
Description : Atopic allergic disorders are characterized by a) a hereditary predisposition. Atopic allergic disorders are characterized by a hereditary predisposition and production of a local reaction to IgE ... of a local reaction to IgE antibodies produced in response to common environmental allergens.
Last Answer : a) a hereditary predisposition. Atopic allergic disorders are characterized by a hereditary predisposition and production of a local reaction to IgE antibodies produced in response to common environmental allergens.
Description : Serum biochemistry of a 60 year old man revealed calcium of 1.98 mmol/l and phosphate of 0.55 mmol/l with an alkaline phosphatase of 450 IU/l.Which among the following mosts suits ... biochemistry? 1) Osteoporosis 2) Osteomalacia 3) Pagets Disease 4) Secondary Hyperparathyroidism 5) Renal failure
Last Answer : Answers-2 Osteomalacia is associated with low calcium and phosphate with raised alkaline phosphatase. Serum biochemistry is normal in osteoporosis. Pagets disease is associated with normal ... renal failure when tertiary hyperparathyroidism sets in there is low calcium with raised phosphate.
Description : Polynucleotide chain of DNA contains (a) a nitrogenous base, deoxyribose sugar and phosphate group (b) a nitrogenous base, ribose sugar and phosphate group (c) deoxyribose sugar ribose sugar and phosphate group (d) a nitrogenous base and phosphate group only
Last Answer : Ans:(a)
Description : Which one of the following statements is not true of RNA? a. RNA contains the monosaccharide ribose. b. RNA is primarily a single-stranded molecule. c. RNA has a sugar-phosphate backbone. d. RNA contains five different nucleotides.
Last Answer : d. RNA contains five different nucleotides.