Description : Secretion of catecholamines is increased in (A) Cushing’s syndrome (B) Addison’s disease (C) Phaeochromocytoma (D) Simmond’s disease
Last Answer : Answer : C
Description : Aldosteronism will present the chemical pathology of (A) Addison’s (B) Cushing’s (C) Grave’s (D) Hartnup’s
Last Answer : Answer : B
Description : Increased urinary excretion of orotic acid can occur in deficiency of (A) Orotate phosphoribosyl transferase (B) OMP decarboxylase (C) Mitochondrial ornithine transcarbamoylase (D) Any of the above
Last Answer : Answer : D
Description : Folic acid deficiency can be diagnosed by increased urinary excretion of (A) Methylmalonate (B) Figlu (C) Cystathionine (D) Creatinine
Description : All the following are true about phenylketonuria except (A) Deficiency of phenylalanine hydroxylase (B) Mental retardation (C) Increased urinary excretion of p-hydroxyphenyl pyruvic acid (D) Decrease serotonin formation
Description : A 53-year-old man presented with hypertension of 150/110 mmHg. He is generally asymptomatic and has no previous medical history of note. He is a smoker of 5 cigarettes daily and drinks ... Adrenocortical adenoma 2) Bartter's syndrome 3) Liddle's syndrome 4) Liquorice ingestion 5) Pheochromocytoma
Last Answer : Answers-1 This patient is most likely to have Conn's syndrome as reflected by the hypokalaemic hypertension. Liquorice ingestion or Liddle's syndrome are again possible causes of ... hypertension (often diastolic hypertension), muscular weakness, paresthesias, headache, polyuria, and polydipsia."
Description : In carcinoid syndrome the argentaffin tissue of the abdominal cavity overproduce (A) Serotonin (B) Histamine (C) Tryptamine (D) Tyrosine
Last Answer : Answer : A
Description : Pentosuria is a rare hereditary disease is characterized by increased urinary excretion of (A) L-xylulose (B) Xylitol (C) Xylulose 5-phosphate (D) Ribose 5-phosphate
Description : All the following statements about phenylketonuria are correct except (A) Phenylalanine cannot be converted into tyrosine (B) Urinary excretion of phenylpyruvate and phenyllactate is increased (C) It ... diet (D) It leads to decreased synthesis of thyroid hormones, catecholamines and melanin
Description : The condition that results when there is an increased production of human growth hormone in an adult is termed A) Cushing's syndrome. B) Addison's disease. C) gigantism. D) dwarfism. E) acromegaly.
Last Answer : E) acromegaly.
Description : Tyrosine hydroxylase is inhibited by (A) Catecholamines (B) α−Methyldopa (C) Phenylalanine (D) Vanillyl mandelic acid
Description : All of the following statements about allopurinol are true except (A) It is a structural analogue of uric acid (B) It can prevent uric acid stones in the kidneys (C) It increases the urinary excretion of xanthine and hypoxanthine (D) It is a competitive inhibitor of xanthine oxidase
Description : All of the following statements about primary gout are true except (A) Uric acid stones may be formed in kidneys (B) Arthritis of small joints occurs commonly (C) Urinary excretion of uric acid is decreased (D) It occurs predominantly in males
Description : A characteristic of pheochromocytoma is elevated urinary excretion of (A) Dopamine (B) Tyrosine (C) Vinylmandelic acid (D) Phenylalanine
Description : A biochemical indication of vitamin B12 deficiency can be obtained by measuring the urinary excretion of (A) Pyruvic acid (B) Malic acid (C) Methyl malonic acid (D) Urocanic acid
Description : Laboratory diagnosis of vitamin B12 deficiency can be made by measuring the urinary excretion of (A) Xanthurenic acid (B) Formiminoglutamic acid (C) Methylmalonic acid (D) Homogentisic acid
Description : Pyridoxine deficiency can be diagnosed by measuring the urinary excretion of xanthurenic acid following a test dose of (A) Glycine (B) Histidine (C) Tryptophan (D) Pyridoxine
Description : Pyridoxine deficiency can be diagnosed by measuring urinary excretion of (A) Pyruvic acid (B) Oxaloacetic acid (C) Xanthurenic acid (D) None of these VITAMINS 119
Description : Histamine is involved as a mediator in the following pathological condition: A. Delayed hypersensitivity reaction B. Inflammation C. Carcinoid syndrome D. Variant angina
Last Answer : B. Inflammation
Description : Which of the following statements regarding hypercalcemia are true? A. The symptoms of hypercalcemia may mimic some symptoms of hyperglycemia. B. Metastatic breast cancer is an unusual cause of ... fluid volume deficit. E. Urinary calcium excretion may be increased by vigorous volume repletion.
Last Answer : Answer: ADE DISCUSSION: Markedly elevated serum calcium levels produce polydipsia, polyuria, and thirst. Vigorous volume repletion and saline diuresis correct the extracellular fluid volume ... , from bony metastasis. The calcitonin effect on calcium is diminished with repeat administrations
Description : Hypokalemia with an accompanying hypochloremic alkalosis may be observed in (A) Cushing’s syndrome(B) Addison’s disease (C) Hyptothyroidism (D) Malnutrition
Description : Hypokalemia occurs in (A) Cushing’s syndrome (B) Addison’s disease (C) Renal failure (D) Advanced dehydration
Description : A high serum potassium, accompanied by a high intracellular potassium occurs in (A) Adrenal insufficiency (B) Any illness (C) Gastrointestinal losses (D) Cushing’s syndrome
Description : Which of the following is noted in cushing’s syndrome, a tumor associated disease of the adrenal cortex? (A) Decreased production of epinephrine (B) Excessive production of epinephrine (C) Excessive production of vasopressin (D) Excessive production of cortisol
Description : In Cushing’s syndrome-a tumour associated disease of adrenal cortex, there is (A) Decreased epinephrine production (B) Excessive cortisol production (C) Excessive epinephrine production (D) Decreased cortsoil production
Description : Excessive secretion of ACTH causes (A) Cushing’s syndrome (B) Addison’s disease (C) Myxoedema (D) Thyrotoxicosis
Description : B.M.R. is subnormal in (A) Addison’s disease (B) Adrenal tumour (C) Cushing’s syndrome (D) Fever
Description : Which of the following techniques would be most useful in the differential diagnosis between ectopic Cushing's syndrome and pituitary dependent Cushing's disease. 1) Urine free cortisol 2) ... Dexamethasone suppression test 3) ACTH concentrations 4) Inferior petrosal sinus sampling 5) CRF test
Last Answer : Answers-4 Inferior petrosal sinus sampling with an elevated central ACTH concentration compared with the peripheral value is the most valuable test in the differential diagnosis of either Cushing's disease or ectopic Cushing's syndrome. The other tests are far less useful in comparison.
Description : In case of wilson’s disease, the features include all of the following except (A) Progressive hepatic cirrhosis (B) Keyser Fleisher ring (C) Aminoaciduria (D) Urinary excretion of Cu is decreased
Description : Daily urinary urobilinogen excretion in adult men is (A) 0–4 mg (B) 5–8 mg (C) 9–12 mg (D) 13–20 mg
Description : Vitamin B12 deficiency can be diagnosed by urinary excretion of (A) Pyruvate (B) Methylmalonate (C) Malate (D) Lactate
Description : In glycinuria daily urinary excretion of glycine ranges from (A) 100–200 mg (B) 300–500 mg (C) 600–1000 mg (D) 1100–1400 mg
Description : Which of the following is a characteristic feature of acute intermittent porphyria? 1) autosomal recessive inheritance 2) excessive faecal protoporphyrin excretion 3) excessive urinary porphobilinigoen between acute attacks 4) hypernatraemia during attacks 5) photosensitivity
Last Answer : Answers-3 Features of acute intermittent porphyria include urinary porphobilinogen excretion raised between attacks, hyponatraemia during an acute attack and autosomal dominant inheritance.
Description : Stature is increased in (A) Gigantism (B) Acromegaly (C) Simmond’s disease(D) Cushing’s disease
Description : Pyridoxine deficiency can be diagnosed by measuring urinary excretion of (A) Pyruvic acid (B) Oxaloacetic acid (C) Xanthurenic acid (D) None of these
Last Answer : (C) Xanthurenic acid
Description : Hypermagnesemia may be observed in (A) Hyperparathyroidism (B) Diabetes mellitus (C) Kwashiorkar (D) Primary aldosteronism
Description : Serum sodium level rises in all of the following except (A) Renal failure (B) Prolonged steroid therapy (C) Aldosteronism (D) Dehydration
Description : Which of the following disorders is characterized by a group of symptoms produced by an excess of free circulating cortisol from the adrenal cortex? a) Cushing's syndrome The patient ... individual with Hashimoto's disease demonstrates inflammation of the thyroid gland, resulting in hypothyroidism.
Last Answer : a) Cushing’s syndrome The patient with Cushing’s syndrome demonstrates truncal obesity, moon face, acne, abdominal striae, and hypertension.
Description : Urine examination (Benedict’s test) of a 40 yr old obese male showed a brick red precipitate. This can result from all except Options: 1) Diabetes Mellitus 2) Drugs 3) Acute post-streptococcal glomerulonephritis 4) Cushing’s syndrome
Last Answer : Correct Answer: 3) Acute post-streptococcal glomerulonephritis
Description : a 20 year old medical student presents with five years history of weight gain, irregular periods and worsening fascial hair. What is the most likely diagnosis? a) Polycystic ovarian disease. b) Hypothyroidism. c) Obesity. d) Cushing’s Syndrome. e) Nephrotic Syndrome.
Last Answer : a) Polycystic ovarian disease.
Description : A young medical student has come to you with complaints of oligomenorrrhea, hirsuitism and weight gain, ultrasound reveals bulky ovaries with sub-capsular cysts. Most likely diagnosis is: a) Ovarian ... syndrome. c) Polycystic ovarian disease. d) Diabetes mellitus. e) Pelvic inflammatory disease
Last Answer : c) Polycystic ovarian disease.
Description : Which disease results when the adrenal cortex produces too much hormone? A) diabetes insipidus B) diabetes mellitus C) Cushing's syndrome D) Addison's disease E) myxedema
Last Answer : C) Cushing's syndrome
Description : The most important indication of mifepristone is: A. Endometriosis B. Cushing's syndrome C. First term abortion D. Second term abortion
Last Answer : C. First term abortion
Description : Presence of significant amount of 5-HIAA in urine indicates (A) Carcinoid in liver (B) Carcinoid in appendix (C) Metastasis of carcinoma of liver (D) Hepatoma
Description : All of the following occur in orotic aciduria except (A) Increased synthesis of pyrimidine nucleotides (B) Increased excretion of orotic acid in urine (C) Decreased synthesis of cytidine triphosphate (D) Retardation of growth
Description : Increased urinary indole acetic acid is diagnostic of (A) Maple syrup urine disease (B) Hartnup disease (C) Homocystinuia (D) Phenylketonuria
Description : Excretion of conjugated bilirubin from liver cells into biliary canaliculi is defective in (A) Gilbert’s disease (B) Crigler-Najjar syndrome (C) Lucey-Driscoll syndrome (D) Rotor’s syndrome
Description : Urinary excretion of Na is regulated by
Last Answer : Urinary excretion of Na is regulated by A. Anterior pituitary B. Posterior pituitory C. Adrenal cortex D. Adrenal medulla
Description : At menopause there is rise in urinary excretion of
Last Answer : At menopause there is rise in urinary excretion of A. FSH B. STH C. MSH D. LH.