Description : In synthesis of Triglyceride from α-Glycero phosphate and acetyl CoA, the first intermediate formed is (A) β-diacyl glycerol (B) Acyl carnitine (C) Monoacyl glycerol(D) Phosphatidic acid
Last Answer : Answer : D
Description : Intermediate in the denovo synthesis of triacyl glycerols include all the following except (A) Fatty acyl CoA (B) CDP diacyl glycerol (C) Glycerol-3-phosphate (D) Lysophosphatidic acid
Last Answer : Answer : B
Description : Glycerol-3-phosphate for the synthesis of triglycerides in adipose tissue is derived from (A) Phosphatidic acid (B) Diacylglycerol (C) Glycerol (D) Glucose
Description : Biosynthesis of Triglyceride and Lecithine both require an intermediate: (A) Monoacyl glycerol phosphate (B) Phosphatidic acid (C) Phosphatidyl ethanol amine (D) Phosphatidyl cytidylate
Description : The common precursor in the biosynthesis of triacylglycerol and phospholipids is (A) 1, 2-Diacylglycerol phosphate (B) 1-Acylglycerol 3-phosphate (C) Glycerol 3-phosphate (D) Dihydroxyacetone phosphate
Last Answer : Answer : A
Description : All statements regarding 3-OH-3 methyl glutaryl CoA are true except (A) It is formed in the cytoplasm (B) Required in ketogenesis (C) Involved in synthesis of Fatty acid (D) An intermediate in cholesterol biosynthesis
Description : Pancreatic lipase converts triacylglycerols into (A) 2, 3-Diacylglycerol (B) 1-Monoacylglycerol (C) 2-Monoacylglycerol (D) 3-Monoacylglycerol
Last Answer : Answer : C
Description : Which of the following statements is not true about phospholipids? (a) They are similar to triacylglycerols except that the middle OH group of glycerol reacts with a phosphate rather than with a ... is a phospholipid. (d) The C-2 carbon of glycerol in phosphoacylglycerols has the R configuration
Last Answer : They are similar to triacylglycerols except that the middle OH group of glycerol reacts with a phosphate rather than with a fatty acid
Description : In adipose tissue, glycerol-3-phosphate required for the synthesis of triglycerides comes mainly from (A) Hydrolysis of pre-existing triglycerides (B) Hydrolysis of phospholipids (C) Dihydroxyacetone phosphate formed in glycolysis (D) Free glycerol
Description : Which of the following lipid is absorbed actively from intestines? (A) Glycerol (B) Cholesterol (C) Monoacylglycerol (D) None of these
Description : Phosphatidic acid on hydrolysis yields (A) Glycerol, fatty acids, phosphoric acid, choline (B) Glycerol, fatty acids, phosphoric acid (C) Glycerol, fatty acids, phosphoric acid, Glucose (D) Sphingol, fatty acids, phosphoric acid
Description : Gangliosides derived from glucosylceramide contain in addition one or more molecules of (A) Sialic acid (B) Glycerol (C) Diacylglycerol (D) Hyaluronic acid
Description : In the biosynthesis of heme, condensation between succinyl CoA and glycine requires (A) NAD+ (B) FAD (C) NADH + H+ (D) B6-phosphate
Description : Synthesis of polyunsaturated fatty acids involves the enzyme systems: (A) Acyl transferase and hydratase (B) Desaturase and elongase (C) Ketoacyl-CoA reductase and hydratase (D) Dihydroxyacetone phosphate
Description : The principal action of insulin in adipose tissue is to inhibit the activity of the (A) Hormone sensitive lipoprotein lipase (B) Glycerol phosphate acyltransferase (C) Acetyl-CoA carboxylase (D) Pyruvate dehydrogenase
Description : Ceramide is formed by the combination of sphingosine and (A) Acetyl-CoA (B) Acyl-CoA (C) Malonyl-CoA (D) Propionyl-CoA
Description : Each of the following can be an intermediate in the synthesis of phosphatidyl choline except (A) Phosphatidyl inositol (B) CDP-choline (C) Phosphatidyl ethanolamine (D) Diacylglycerol
Description : In the biosynthesis of the iron protoporphyrin, the product of the condensation between succinyl-CoA and glycine is (A) α-Amino β-ketoadipic acid (B) δ-Aminolevulinate (C) Hydroxymethylbilane (D) Uroporphyrinogen I
Description : Glycerol released from adipose tissue by hydrolysis of triglycerides is mainly (A) Taken up by liver (B) Taken up by extrahepatic tissues (C) Reutilised in adipose tissue (D) Excreted from the body FATS AND FATTY ACID METABOLISM 85
Description : Insulin regulates fatty acid synthesis by (A) Dephosphorylating of acetyl CoA carboxylase (B) Activating phosphorylase (C) Inhibiting malonyl CoA formation (D) Controlling carnitine-Acyl CoA transferase activity
Description : This catalyzes formation of CoA derivatives from fatty acid, CoA and ATP: (A) Acyl CoA dehydrogenase (B) Enoyl hydrase (C) β-OH acyl CoA dehydrogenase (D) Thio kinase
Description : Both Acyl carrier protein (ACP) of fatty acid synthetase and coenzyme (CoA) are (A) Contain reactive phosphorylated (B) Contain thymidine (C) Contain phosphopantetheine reactive groups (D) Contain cystine reactive groups
Description : The enzyme regulating extramitochondrial fatty acid synthesis is (A) Thioesterase (B) Acetyl CoA carboxylase (C) Acyl transferase (D) Multi-enzyme complex
Description : During each cycle of on going fatty acid oxidation, all the following compounds are generated except (A) H2O (B) Acetyl CoA (C) Fatty acyl CoA (D) NADH FATS AND FATTY ACID METABOLISM 103
Description : Acetyl CoA required for extra mitochondrial fatty acid synthesis is produced by (A) Pyruvate dehydrogenase complex (B) Citrate lyase (C) Thiolase (D) Carnitine-acyl transferase
Description : During each cycle of β-oxidation of fatty acid, all the following compounds are generated except (A) NADH (B) H2O (C) FAD (D) Acyl CoA
Description : The enzyme acyl-CoA synthase catalyses the conversion of a fatty acid of an active fatty acid in the presence of (A) AMP (B) ADP (C) ATP (D) GTP
Description : All the following correctly describe the intermediate 3-OH-3-methyl glutaryl CoA except (A) It is generated enzymatically in the mitochondrial matrix (B) It is formed in the cytoplasm (C) It inhibits the first step in cholesterol synthesis (D) It is involved in the synthesis of ketone bodies
Description : Long chain fatty acids are first activated to acyl CoA in the (A) Cytosol (B) Mitochodria (C) Ribosomes (D) Microsome
Description : In the biosynthesis of cholesterol, the rate limiting enzyme is (A) Mevalonate kinase (B) HMG-CoA synthetase (C) HMG-CoA reductase (D) Cis-prenyl transferase
Description : In the biosynthesis of cholesterol, the step which controls the rate and locus of metabolic regulation is (A) Geranyl pyrophosphate farnesyl pyrophosphate (B) Squalene → lanosterol (C) HMG CoA → mevalonate (D) Lanosterol → 1, 4-desmethyl lanosterol
Description : In the pathway leading to biosynthesis of acetoacetate from acetyl-CoA in liver, the immediate precursor of aceotacetate is (A) Acetoacetyl-CoA (B) 3-Hydroxybutyryl-CoA (C) 3-Hydroxy-3-methyl-glutaryl-CoA (D) 3-Hydroxybutyrate
Description : The rage limiting step cholesterol biosynthesis is (A) Squalene synthetase (B) Mevalonate kinase (C) HMG CoA synthetase (D) HMG CoA reductase
Description : A metabolite which is common to pathways of cholesterol biosynthesis from acetyl-CoA and cholecalciferol formation from cholesterol is (A) Zymosterol (B) Lumisterol (C) Ergosterol (D) 7 Dehydrocholesterol
Description : The ‘Committed step’ in the biosynthesis of cholesterol from acetyl CoA is (A) Formation of acetoacetyl CoA from acetyl CoA (B) Formation of mevalonate from HMG CoA (C) Formation of HMG CoA from acetyl CoA and acetoacetyl CoA (D) Formation of squalene by squalene synthetase
Description : Salivary lipase converts dietary triglycerides into (A) Diglycerides and fatty acids (B) Monoglycerides and fatty acids (C) Glycerol and fatty acids (D) All of these
Description : FAD containing enzyme, catalyzing formation of α, β unsaturated fatty acyl CoA derivative. (A) Acyl CoA dehydrogenase (B) Enoyl hydrase (C) β-OH acyl CoA dehydrogenase (D) Thiolase
Description : Conversion of fatty acyl-CoA to an acylCoA derivative having 2 more carbon atoms involves as acetyl donar: (A) Acetyl-CoA (B) Succinyl-CoA (C) Propionyl-CoA (D) Malonyl-CoA
Description : Carboxylation of acetyl-CoA to malonylCoA requires the enzyme: (A) Acetyl-CoA carboxylase (B) Pyruvate carboxylase (C) Acetyl transacylase (D) Acyl CoA-synthetase
Description : Acetyl-CoA is the principal building block of fatty acids. It is produced within the mitochondria and does not diffuse readily into cytosol. The availability of acetyl CoA involves (A) Carnitine acyl transferase (B) Pyruvate dehydrogenase (C) Citrate lyase (D) Thiolase
Description : The starting material for ketogenesis is (A) Acyl-CoA (B) Acetyl-CoA (C) Acetoacetyl-CoA (D) Malonyl-CoA
Description : The coenzyme involved in dehydrogenation of 3-hydroxy acyl-CoA is (A) FAD (B) FMN (C) NAD (D) NADP
Description : In β-oxidation, the coenzyme for acyl-CoA dehydrogenase is (A) FMN (B) NAD (C) NADP (D) FAD
Description : The formation of ∆2-trans-enoyl-CoA from acyl-CoA requires the enzyme: (A) Acyl-CoA synthetase (B) Acyl-CoA dehydrogenase (C) 3-Hydroxy acyl-CoA dehydrogenase (D) Thiolase
Description : Riboflavin is a coenzyme in the reaction catalysed by the enzyme (A) Acyl CoA synthetase (B) Acyl CoA dehydrogenase (C) β-Hydroxy acyl CoA (D) Enoyl CoA dehydrogenase
Description : Long chain fatty acyl CoA esters are transported across the mitochondrial membrane by (A) cAMP (B) Prostaglandin (C) Carnitine (D) Choline
Description : The carbon chain of fatty acids is shortened by 2 carbon atoms at a time. This involves successive reactions catalysed by 4-enzymes. These act the following order: (A) Acetyl CoA dehydrogenase, ... CoA dehydrogenase (D) Enoyl hydrase, β-OH acyl CoA dehydrogenase, acyl CoA dehydrogenase, thiolose,
Description : Fatty acids are activated to acyl CoA by the enzyme thiokinase: (A) NAD+ (B) NADP+ (C) CoA (D) FAD+
Description : Acyl-CoA dehydrogenase converts Acyl CoA to α-β unsaturated acyl-CoA in presence of the coenzyme: (A) NAD+ (B) NADP+ (C) ATP (D) FAD
Description : Long chain acyl CoA penetrates mitochondria in the presence of (A) Palmitate (B) Carnitine (C) Sorbitol (D) DNP