Description : Alkaline phosphatase is present in (A) Liver (B) Bones (C) Intestinal mucosa (D) All of these
Last Answer : Answer : D
Description : Characteristics of Vitamin D and its metabolites include which one of the following? (a) Act to decrease serum levels of calcium (b) Activation of their Vitamin D receptors increases cellular CAMP ... Vitamin D increase renal excretion of calcium (e) Vitamin D deficiency results in Pager's disease
Last Answer : Ans: C
Description : Calcium absorption is interfered by (A) Protein in diet (B) Phytic acid in cereals (C) Alkaline intestinal pH (D) Vitamin D
Last Answer : Answer : B
Description : A high plasma calcium level decreases intestinal absorption of calcium by (A) Stimulating the secretion of parathormone (B) Inhibiting the secretion of parathormone (C) Decreasing the synthesis of cholecalciferol (D) Inhibiting the secretion of thyrocalcitonin
Description : Iron absorption is hampered by (A) In achlorhydria (B) When ferritin content of intestinal mucosa is low (C) When saturation of plasma transferring is low (D) When erythropoietic activity is increased
Last Answer : Answer : A
Description : The harmone acting directly on intestinal mucosa and stimulating glucose absorption is (A) Insulin (B) Glucagon (C) Thyroxine (D) Vasopressin
Last Answer : Answer : C
Description : All the following statements about obstructive jaundice are true except (A) Prothrombin time may be prolonged due to impaired absorption of vitamin K (B) Serum alkaline phosphatase may be raised ... systemic circulation due to biliary obstruction (D) There is no defect in conjugation of bilirubin
Description : A 19 year-old female is referred following a visit to the dentist where marked erosion of her teeth was noted. She was entirely asymptomatic and her only medication was the oral contraceptive pill ... ) Bulimia nervosa 2) Conn's syndrome 3) Laxative abuse 4) Pregnancy 5) Primary hypoparathyroidism
Last Answer : Answers-5 This patient has tooth erosion associated with hypokalaemic metabolic alkalosis and hypocalcaemia. This suggests a diagnosis of hypoparathyroidism. Conn's is unlikely in this age group, is ... raised alkaline phosphatase would not be expected. Early pregnancy would not fit this picture.
Description : Serum biochemistry of a 60 year old man revealed calcium of 1.98 mmol/l and phosphate of 0.55 mmol/l with an alkaline phosphatase of 450 IU/l.Which among the following mosts suits ... biochemistry? 1) Osteoporosis 2) Osteomalacia 3) Pagets Disease 4) Secondary Hyperparathyroidism 5) Renal failure
Last Answer : Answers-2 Osteomalacia is associated with low calcium and phosphate with raised alkaline phosphatase. Serum biochemistry is normal in osteoporosis. Pagets disease is associated with normal ... renal failure when tertiary hyperparathyroidism sets in there is low calcium with raised phosphate.
Description : Lactose or its analogues act as positive regulators of lac operon by (A) Attaching to i gene and preventing its expression (B) Increasing the synthesis of catabolite gene activator protein (C) ... holoenzyme (D) Binding to repressor subunits so that the repressor cannot attach to the operator locus
Description : All the following statements about ceruloplasmin are correct except (A) It is a copper-containing protein (B) It possesses oxidase activity (C) It is synthesised in intestinal mucosa (D) Its plasma level is decreased inWilson’s disease
Description : More than half of the protein of the liver and intestinal mucosa are broken down and resynthesised in (A) 10 days (B) 12 days (C) 15 days (D) 18 days
Description : Calcium is important in skeletal muscle contraction because it (a) binds to troponin to remove the masking of active sites on actin for myosin (b) activates the myosin ATPase by binding to it ... filament (d) prevents the formation of bonds between the myosin cross bridges and the actin filament.
Last Answer : (a) binds to troponin to remove the masking of active sites on actin for myosin
Description : Calcium is important in skeletal muscle contraction because it :- (1) binds to troponin to remove the masking of active sites on actin for myosin. (2) activates the myosin ATPase by binding to ... filament. (4) prevents the formation of bonds between the myosin cross bridges and the actin filament.
Last Answer : (1) binds to troponin to remove the masking of active sites on actin for myosin.
Description : From the internal surface to the external surface, the digestive tube wall is made of mucosa (epithelial tissue responsible for the intestinal absorption), submucosa (connective tissue beneath the ... within the abdominal cavity. Digestion System - Image Diversity: histology of the digestive tube
Last Answer : What is the location of the salivary glands in humans?
Description : Which one of the following statements is true regarding digestion and absorption of food in humans? (a) Fructose and amino acids are absorbed through intestinal mucosa with the help of carrier ions ... amylase in our mouth. (d) Oxyntic cells in our stomach secrete the proenzyme pepsinogen.
Last Answer : (a) Fructose and amino acids are absorbed through intestinal mucosa with the help of carrier ions like Na
Description : The success of oral rehydration therapy of diarrhoea depends upon the following process in the intestinal mucosa: A. Sodium pump mediated Na+ absorption B. Glucose coupled Na+ absorption C. Bicarbonate coupled Na+ absorption D. Passive Na+ diffusion secondary to nutrient absorption
Last Answer : B. Glucose coupled Na+ absorption
Description : Tricyclic antidepressants can alter the oral absorption of many drugs by: A. Complexing with the other drug in the intestinal lumen B. Altering gut motility C. Altering gut flora D. Damaging gut mucosa
Last Answer : B. Altering gut motility
Description : Hyperglycemic effect of glucocorticoids is due to (A) Inactivation of protein phosphatase (B) Inactivation of fructose 1,6-biphosphatase (C) Stimulation of synthesis of pyruvate carboxylase (D) Stimulation of synthesis of eltroxykinase
Description : High plasma protein binding: A. Increases volume of distribution of the drug B. Facilitates glomerular filtration of the drug C. Minimises drug interactions D. Generally makes the drug long acting
Last Answer : D. Generally makes the drug long acting
Description : Intestinal absorption of magnesium is increased in (A) Calcium deficient diet (B) High calcium diet (C) High oxalate diet (D) High phytate diet
Description : PTH causes all of the following except (A) Increased intestinal absorption of calcium (B) Increased intestinal absorption of phosphate (C) Increased tubular reabsorption of calcium (D) Increased tubular reabsorption of phosphate
Description : Intestinal absorption of zinc is retarded by (A) Calcium (B) Cadmium (C) Phytate (D) All of these
Description : Intestinal absorption of calcium occurs by (A) Active takeup (B) Simple diffusion (C) Facilitated diffusion (D) Endocytosis
Description : Calcitriol synthesis involves (A) Both liver and kidney (B) Intestine (C) Adipose tissue (D) Muscle
Description : All the following statements about Wilson’s disease are correct except (A) It is a genetic disease (B) The defect involves copper-dependent P-type ATPase (C) Copper is deposited in liver, basal ganglia and around cornea (D) Plasma copper level is increased in it
Description : Tubular reabsorption of calcium is increased by (A) Cholecalciferol (B) 25-Hydroxycholecalciferol (C) Calcitriol (D) All of these
Description : Decrease in absorption of which of the following vitamins in the geriatric patient results in pernicious anemia? a) B12 Vitamin B12 requires the intrinsic factor secreted by the gastric mucosa for ... results in an inability to absorb calcium. d) B6 Vitamin B6 affects neuromuscular function.
Last Answer : a) B12 Vitamin B12 requires the intrinsic factor secreted by the gastric mucosa for absorption.
Description : Ferritin is present in (A) Intestinal mucosa (B) Liver (C) Spleen (D) All of these
Description : 25-Hydroxylation of vitamin D occurs in (A) Skin (B) Liver (C) Kidneys (D) Intestinal mucosa
Description : Deficiency of vitamin B12 can occur because of (A) Decreased intake of vitamin B12 (B) Atrophy of gastric mucosa (C) Intestinal malabsorption (D) All of these
Description : Retinal is reduced to retinol in intestinal mucosa by a specific retinaldehyde reductase utilising (A) NADPH + H+ (B) FAD (C) NAD (D) NADH + H+
Description : Zinc is a cofactor for (A) Acid phosphatase (B) Alkaline phosphatase (C) Amylase (D) Lipase
Description : Serum alkaline phosphatase is greatly increased in (A) Haemolytic jaundice (B) Hepatic jaundice (C) Obstructive jaundice (D) None of these
Description : An inherited or acquired renal tubular defect in the reabsorption of phosphate (Vit D resistant ricket) is characterized with (A) Normal serum Phosphate (B) High serum phosphate (C ... blood phosphorous with elevated alkaline Phosphate (D) A high blood phosphorous with decreased alkaline phosphatase
Description : Which of the following is known as bone forming enzyme? (A) Alkaline phosphatase (B) Acid phosphatase (C) Leucine aminopeptidase (D) γ-glutamyl transpeptidase
Description : All of the following are zinc-containing enzymes except (A) Acid Phosphatase (B) Alkaline Phosphatase (C) Carbonic anhydrase (D) RNA polymerase
Description : The first enzyme found to have isoenzymes was (A) Alkaline Phosphatase (B) Lactate dehydrogenase (C) Acid Phosphatase (D) Creatine kinase
Description : Alkaline phosphatase is present in (A) Liver (B) Bones (C) Placenta (D) All of these
Description : The normal serum alkaline phosphatase activity ranges from (A) 1.0–5.0 KA units/100 ml (B) 5.0–13.0 KA units/100 ml (C) 0.8–2.3 KA units/100 ml (D) 13.0–21.0 KA units/100 ml
Description : All the following statements about obstructive jaundice are true except (A) Conjugated bilirubin in serum is normal (B) Total bilirubin in serum is raised (C) Bile salts are present in urine (D) Serum alkaline phosphatase is raised
Description : Hepatocellular jaundice as compared to pure obstructive type of jaundice is characterized by (A) Increased serum alkaline phosphate, LDH and ALT (B) Decreased serum alkaline phosphatase, LDH and ALT (C ... levels of LDH and ALT (D) Decreased serum alkaline phosphatase and increased serum LDH and ALT
Description : A jaundice in which serum alanine transaminase and alkaline phosphatase are normal is (A) Hepatic jaundice (B) Hemolytic jaundice (C) Parenchymatous jaundice (D) Obstructive Jaundice
Description : It is said that nucleotide phosphatase (NTP) is a better index of obstructive liver disease than alkaline phosphatase (ALP), why?
Last Answer : ALP level is increased in both liver and bone diseases, but NTP is only in liver diseases.
Description : For alkaline phosphatase, how many iso-enzymes are present?
Last Answer : Six.
Description : Alkaline phosphatase level in serum is elevated in which conditions?
Last Answer : Moderate increase is seen in hepatic diseases (infective hepatitis, alcoholic hepatitis). High levels may be noticed in obstructive jaundice or cholestasis. Very high levels are seen in bone diseases such as Pagetís disease, rickets, osteomalacia, osteoblastoma, metastatic carcinoma of bone.
Description : All of the following statements about the enzymic complex that carries out the synthesis of ATP during oxidative phosphorylation are correct except (A) It is located on the matrix side of the inner ... inhibited by oligomycin (C) It can exhibit ATPase activity (D) It can bind molecular O2
Last Answer : D