It is said that nucleotide phosphatase (NTP) is a better index of obstructive liver disease than alkaline phosphatase (ALP), why?

It is said that nucleotide phosphatase (NTP) is a better index of obstructive liver disease than alkaline phosphatase (ALP), why?
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1 Answer

Answer :

ALP level is increased in both liver and bone diseases, but NTP is only in liver diseases. 
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Related questions

All the following statements about obstructive jaundice are true except (A) Prothrombin time may be prolonged due to impaired absorption of vitamin K (B) Serum alkaline phosphatase may be raised due to increased release of the enzyme from liver cells (C) Bile salts may enter systemic circulation due to biliary obstruction (D) There is no defect in conjugation of bilirubin

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Last Answer : Answer : B

Serum alkaline phosphatase is greatly increased in (A) Haemolytic jaundice (B) Hepatic jaundice (C) Obstructive jaundice (D) None of these

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Last Answer : Answer : C

All the following statements about obstructive jaundice are true except (A) Conjugated bilirubin in serum is normal (B) Total bilirubin in serum is raised (C) Bile salts are present in urine (D) Serum alkaline phosphatase is raised

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Last Answer : Answer : A

Hepatocellular jaundice as compared to pure obstructive type of jaundice is characterized by (A) Increased serum alkaline phosphate, LDH and ALT (B) Decreased serum alkaline phosphatase, LDH and ALT (C) Increased serum alkaline phosphatase and decreased levels of LDH and ALT (D) Decreased serum alkaline phosphatase and increased serum LDH and ALT

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Last Answer : Answer : D

A jaundice in which serum alanine transaminase and alkaline phosphatase are normal is (A) Hepatic jaundice (B) Hemolytic jaundice (C) Parenchymatous jaundice (D) Obstructive Jaundice

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Last Answer : Answer : B

Which enzyme estimation will be helpful in differentiating the elevated serum ALP found in obstructive jaundice as well as bone disorders? (A) Serum AST (B) Serum ALT (C) Serum LDH (D) Serum γ-GT

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Last Answer : Answer : D

If results of the serum bilirubin, serum ALP, LDH and AST determinations suggest obstructive jaundice, the best confirmatory test would be the estimation of (A) Serum ALT (B) Serum 5’ nucleotidase (C) Serum Pseudo cholinesterase (D) None of these

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Last Answer : Answer : B

Patients with hepatocellular jaundice, as compared to those with purely obstructive jaundice tend to have (A) Lower serum ALP, LDH and AST activity (B) Lower serum ALP, Higher LDH and AST activity (C) Higher serum ALP, LDH and AST activity (D) Higher serum ALP, Lower LDH and AST activity

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Last Answer : Answer : B

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Description : Which of the following enzyme typically elevated in alcoholism? (A) Serum ALP (B) Serum GOT (C) Serum γ-GT (D) Serum acid phosphatase

Last Answer : Answer : C

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Alkaline phosphatase is present in (A) Liver (B) Bones (C) Placenta (D) All of these

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A 19 year-old female is referred following a visit to the dentist where marked erosion of her teeth was noted. She was entirely asymptomatic and her only medication was the oral contraceptive pill. On examination her blood pressure was 110/70 mmHg and her body mass index was 21.5 kg/m2 (18 - 25). Investigations sodium 135 mmol/l potassium 2.1 mmol/l bicarbonate 42 mmol/l urea 2.6 mol/L corrected calcium 2.08 mmol/ alkaline phosphatase 201 iu/l (50-110) What is the most likely diagnosis? 1) Bulimia nervosa 2) Conn's syndrome 3) Laxative abuse 4) Pregnancy 5) Primary hypoparathyroidism

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Serum biochemistry of a 60 year old man revealed calcium of 1.98 mmol/l and phosphate of 0.55 mmol/l with an alkaline phosphatase of 450 IU/l.Which among the following mosts suits with the above serum biochemistry? 1) Osteoporosis 2) Osteomalacia 3) Pagets Disease 4) Secondary Hyperparathyroidism 5) Renal failure

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Description : Has anyone had a low alkaline phosphatase reading before on a liver blood test?

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Description : The liver enzyme which is sensitive indicator of liver cell injury and is most helpful in recognizing acute hepatocellular diseases is Options: 1) Alkaline Phosphatase 2) Aspartate aminotransferase 3) Gamma glutamyl Transpeptidase 4) Creatine Phosphokinase

Last Answer : Correct Answer: 2) Aspartate aminotransferase

Von Gierke’s disease is characterized by the deficiency of (A) Glucose-6-phosphatase (B) α -1→ 4 Glucosidase (C) 1→ 6 Glucosidase (D) Liver phosphorylase

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Serum acid phosphatase level increases in (A) Metastatic carcinoma of prostate (B) Myocardial infarction (C) Wilson’s disease (D) Liver diseases

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McArdle’s disease is due to the deficiency of (A) Glucose-6-phosphatase (B) Phosphofructokinase (C) Liver phosphorylase (D) muscle phosphorylase

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Last Answer : D

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Calcitriol facilitates calcium absorption by increasing the synthesis of the following in intestinal mucosa: (A) Calcium Binding Protein (B) Alkaline Phosphatase (C) Calcium-dependent ATPase (D) All of these

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All of the following are zinc-containing enzymes except (A) Acid Phosphatase (B) Alkaline Phosphatase (C) Carbonic anhydrase (D) RNA polymerase

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For alkaline phosphatase, how many iso-enzymes are present?

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Alkaline phosphatase level in serum is elevated in which conditions?

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The hydrolysis of Glucose-6-P is catalysed by a phosphatase that is not formed in which of the following? (A) Liver (B) Kidney (C) Muscle (D) Small intestine

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The hydrolysis of Glucose-6-phosphate is catalysed by a specific phosphatase which is found only in (A) Liver, intestines and kidneys (B) Brain, spleen and adrenals (C) Striated muscle (D) Plasma

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