An increased serum ‘Iron’ and decreased ‘Fe’ binding capacity are found in (A) Fe-deficiency anaemia (B) Sideroblastic anaemia (C) Thalassaemia (D) Anaemia of chromic disorders

An increased serum ‘Iron’ and decreased ‘Fe’ binding capacity are found in (A) Fe-deficiency anaemia (B) Sideroblastic anaemia (C) Thalassaemia (D) Anaemia of chromic disorders
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An increased serum iron and decreased iron binding capacity is found in (A) Fe deficiency anemia (B) Sideroblastic anemia (C) Folate deficiency anemia (D) Sickle cell anemia

Description : An increased serum iron and decreased iron binding capacity is found in (A) Fe deficiency anemia (B) Sideroblastic anemia (C) Folate deficiency anemia (D) Sickle cell anemia

Last Answer : Answer : B

Iron therapy is ineffective in which of the following conditions: (A) Chronic blood loss (B) Inadequate Fe intake (C) Hypochromic anaemia of pregnancy (D) Thalassaemia minor

Description : Iron therapy is ineffective in which of the following conditions: (A) Chronic blood loss (B) Inadequate Fe intake (C) Hypochromic anaemia of pregnancy (D) Thalassaemia minor

Last Answer : Answer : D

Which of the following is true? Hypochromic anaemia is not due to iron deficiency except (A) Serum ‘Fe’ is high (B) Normal/low transferrin (C) Stainable iron in bone marrow (D) Iron therapy is affective

Description : Which of the following is true? Hypochromic anaemia is not due to iron deficiency except (A) Serum ‘Fe’ is high (B) Normal/low transferrin (C) Stainable iron in bone marrow (D) Iron therapy is affective

Last Answer : Answer : D

The most striking example of point mutation is found in a disease called (a) Down’s syndrome (b) sickle cell anaemia (c) thalassaemia (d) night blindness.

Description : The most striking example of point mutation is found in a disease called (a) Down’s syndrome (b) sickle cell anaemia (c) thalassaemia (d) night blindness.

Last Answer : (b) sickle cell anaemia

Assertion: Gastrectomy can lead to iron-deficiency or anaemia. Reason: HCl of gastric juice converts `Fe^(3+)` into `Fe^(2+)` which makes iron absorba

Description : Assertion: Gastrectomy can lead to iron-deficiency or anaemia. Reason: HCl of gastric juice converts `Fe^(3+)` into `Fe^(2+)` which makes iron absorba

Last Answer : Assertion: Gastrectomy can lead to iron-deficiency or anaemia. Reason: HCl of gastric juice converts `Fe^ ... `Fe^(2+)` which makes iron absorbabale.

In iron deficiency anaemia, the following is decreased: a. MCV (mean cell volume) b. ferritin c. MCH (mean cell haemoglobin) d. all above

Description : In iron deficiency anaemia, the following is decreased: a. MCV (mean cell volume) b. ferritin c. MCH (mean cell haemoglobin) d. all above

Last Answer : all above

.Which one of the following conditions though harmful in itself, is also potential saviour from a mosquito borne infectious disease ? (a) Thalassaemia (b) Sickle cell anaemia (c) Pernicious anaemia (d) Leukaemia

Description : .Which one of the following conditions though harmful in itself, is also potential saviour from a mosquito borne infectious disease ? (a) Thalassaemia (b) Sickle cell anaemia (c) Pernicious anaemia (d) Leukaemia

Last Answer : (b) Sickle cell anaemia

In iron deficiency anemia (A) The plasma bound iron is low (B) The plasma bound iron is high (C) Total iron binding capacity is low (D) Both the plasma bound iron and total iron binding capacity are low

Description : In iron deficiency anemia (A) The plasma bound iron is low (B) The plasma bound iron is high (C) Total iron binding capacity is low (D) Both the plasma bound iron and total iron binding capacity are low

Last Answer : Answer : A

Which of the following statements concerning abnormalities of the haemoglobin molecule is true? 1) Alpha thalassaemia is due to a deficiency of beta-chain production 2) HbS is caused by a single base mutation on the beta-chain 3) genes for the alpha and beta chains are located on the same chromosome 4) in thalassaemia persistance of HbF is an adverse prognostic sign 5) oliguneoclitide probes may assist in the diagnosis of haemoglobinopathies

Description : Which of the following statements concerning abnormalities of the haemoglobin molecule is true? 1) Alpha thalassaemia is due to a deficiency of beta-chain production 2) HbS is caused by a ... is an adverse prognostic sign 5) oliguneoclitide probes may assist in the diagnosis of haemoglobinopathies

Last Answer : Answers-2 Alpha Thalassaemia is due to abnormalities of the alpha chain. Persistence of HbF has survival advnatages in severely affected subjects. C-alpha 16, beta 11. e-Hb electrophoresis(Dr Shu Ho)

Hepatocellular jaundice as compared to pure obstructive type of jaundice is characterized by (A) Increased serum alkaline phosphate, LDH and ALT (B) Decreased serum alkaline phosphatase, LDH and ALT (C) Increased serum alkaline phosphatase and decreased levels of LDH and ALT (D) Decreased serum alkaline phosphatase and increased serum LDH and ALT

Description : Hepatocellular jaundice as compared to pure obstructive type of jaundice is characterized by (A) Increased serum alkaline phosphate, LDH and ALT (B) Decreased serum alkaline phosphatase, LDH and ALT (C ... levels of LDH and ALT (D) Decreased serum alkaline phosphatase and increased serum LDH and ALT

Last Answer : Answer : D

Increased serum alanine during fasting is due to (A) Breakdown of muscle proteins (B) Decreased utilization of non essential amino acids (C) Leakage of aminoacids to plasma (D) Impaired renal function

Description : Increased serum alanine during fasting is due to (A) Breakdown of muscle proteins (B) Decreased utilization of non essential amino acids (C) Leakage of aminoacids to plasma (D) Impaired renal function

Last Answer : Answer : A

Which enzyme estimation will be helpful in differentiating the elevated serum ALP found in obstructive jaundice as well as bone disorders? (A) Serum AST (B) Serum ALT (C) Serum LDH (D) Serum γ-GT

Description : Which enzyme estimation will be helpful in differentiating the elevated serum ALP found in obstructive jaundice as well as bone disorders? (A) Serum AST (B) Serum ALT (C) Serum LDH (D) Serum γ-GT

Last Answer : Answer : D

Iron deficiency causes (A) Normocytic anaemia (B) Microcytic anaemia (C) Megaloblastic anaemia (D) Pernicious anaemia

Description : Iron deficiency causes (A) Normocytic anaemia (B) Microcytic anaemia (C) Megaloblastic anaemia (D) Pernicious anaemia

Last Answer : Answer : B

An important finding in glycinuria is (A) Excess excretion of oxalate in the urine (B) Deficiency of enzyme glycinase (C) Significantly increased serum glycine level (D) Defect in renal tubular reabsorption of glycine

Description : An important finding in glycinuria is (A) Excess excretion of oxalate in the urine (B) Deficiency of enzyme glycinase (C) Significantly increased serum glycine level (D) Defect in renal tubular reabsorption of glycine

Last Answer : Answer : D

A hypochromic microcytic anaemia which increases Fe, store in the bone marrow may be (A) Folic acid responsive (B) Vitamin B12 responsive (C) Pyridoxine responsive (D) Vitamin C responsive

Description : A hypochromic microcytic anaemia which increases Fe, store in the bone marrow may be (A) Folic acid responsive (B) Vitamin B12 responsive (C) Pyridoxine responsive (D) Vitamin C responsive

Last Answer : Answer : D

A hypochromic necrocytic anaemia with increase Fe stores in the bone marrow may be (A) Folic acid responsive (B) Vitamin B12 responsive (C) Pyridoxine responsive (D) Vitamin C responsive

Description : A hypochromic necrocytic anaemia with increase Fe stores in the bone marrow may be (A) Folic acid responsive (B) Vitamin B12 responsive (C) Pyridoxine responsive (D) Vitamin C responsive

Last Answer : Answer : C

The “Primaquin sensitivity types of haemolytic anaemia has been found to relate to reduced R.B.C activity of which enzyme? (A) Pyruvate kinase deficiency (B) Glucose-6-phosphatase deficiency (C) Glucose-6-p dehydrogenase deficiency (D) Hexokinase deficiency

Description : The “Primaquin sensitivity types of haemolytic anaemia has been found to relate to reduced R.B.C activity of which enzyme? (A) Pyruvate kinase deficiency (B) Glucose-6-phosphatase deficiency (C) Glucose-6-p dehydrogenase deficiency (D) Hexokinase deficiency

Last Answer : C

In inherited deficiency of hypoxanthine guanine phosphoribosyl transferase (A) De novo synthesis of purine nucleotides is decreased (B) Salvage of purines is decreased (C) Salvage of purines is increased (D) Synthesis of uric acid is decreased

Description : In inherited deficiency of hypoxanthine guanine phosphoribosyl transferase (A) De novo synthesis of purine nucleotides is decreased (B) Salvage of purines is decreased (C) Salvage of purines is increased (D) Synthesis of uric acid is decreased

Last Answer : Answer : B

Which one of the following would be expected in pyruvate kinase deficiency? (A) Increased levels of lactate in the R.B.C (B) Hemolytic anemia (C) Decreased ratio of ADP to ATP in R.B.C (D) Increased phosphorylation of Glucose to Glucose-6-phosphate

Description : Which one of the following would be expected in pyruvate kinase deficiency? (A) Increased levels of lactate in the R.B.C (B) Hemolytic anemia (C) Decreased ratio of ADP to ATP in R.B.C (D) Increased phosphorylation of Glucose to Glucose-6-phosphate

Last Answer : B

The primary mechanism underlying the resistance of gram-positive organisms to macrolide antibiotics is (a) Methylation of binding sites on the 50S ribosomal subunit (b) Formation of esterases that hydrolyze the lactone ring (c) Increased activity of efflux mechanisms (d) Formation of drug-inactivating acetyltranferases (e) Decreased drug permeability of the cytoplasmic membrane

Description : The primary mechanism underlying the resistance of gram-positive organisms to macrolide antibiotics is (a) Methylation of binding sites on the 50S ribosomal subunit (b) Formation of ... ) Formation of drug-inactivating acetyltranferases (e) Decreased drug permeability of the cytoplasmic membrane

Last Answer : Ans: A

Answer: a, b, c, d Free oxygen radicals are chemical species that are intermediates in the normal process of cellular respiration. Oxidants that are free radicals have been implicated as initiators of reactions which lead to a variety of cellular injuries. Oxidants are derived from several sources, notably phagocytes. Among the effects of oxygen free radicals are membrane lipid peroxidation, DNA strand breaks, cytoskeletal disassembly and inhibition of glucose metabolism leading to decreased cellular ATP concentrations. (Figure 6-16) 187 Which of the following acute-phase protein levels are increased in human plasma following acute inflammation? a. C-reactive protein b. Serum amyloid c. a -Proteinase inhibitor d. Fibrinogen e. Albumin

Description : Answer: a, b, c, d Free oxygen radicals are chemical species that are intermediates in the normal process of cellular respiration. Oxidants that are free radicals have been implicated as initiators of ... a. C-reactive protein b. Serum amyloid c. a -Proteinase inhibitor d. Fibrinogen e. Albumin

Last Answer : Answer: a, b, c, d The acute-phase response is a series of homeostatic responses of the organism to tissue injury in infection and inflammation. After an inflammatory stimulus occurs, a number ... 30% to 50% of the level before injury. The reason for the decrease in production is poorly understood

Increased serum levels of which of the following may be associated with a decreased risk of atherosclerosis? (a) Very low-density lipoproteins (VLDL) (b) Low-density lipoproteins (LDL) (c) Intermediate – density lipoproteins (IDL) (d) High-density lipoproteins (HDL) (e) Cholesterol

Description : Increased serum levels of which of the following may be associated with a decreased risk of atherosclerosis? (a) Very low-density lipoproteins (VLDL) (b) Low-density lipoproteins (LDL) (c) Intermediate – density lipoproteins (IDL) (d) High-density lipoproteins (HDL) (e) Cholesterol

Last Answer : Ans: D

Each of the following may contribute to formation of oedema EXCEPT C A. decreased plasma oncotic pressure increased intravascular hydrostatic pressure C. increased serum albumin D. decreased serum proteins

Description : Each of the following may contribute to formation of oedema EXCEPT C A. decreased plasma oncotic pressure increased intravascular hydrostatic pressure C. increased serum albumin D. decreased serum proteins

Last Answer : increased serum albumi

BMR is decreased in (A) Pregnancy (B) Starvation (C) Anaemia (D) Fever

Description : BMR is decreased in (A) Pregnancy (B) Starvation (C) Anaemia (D) Fever

Last Answer : Answer : B

In hepatic diseases (A) Both the bound iron and total iron binding capacity of the plasma may be low (B) Both the bound iron and total iron binding capacity of the plasma may be high (C) Only bound iron may be high (D) Only the total iron binding capacity may be high

Description : In hepatic diseases (A) Both the bound iron and total iron binding capacity of the plasma may be low (B) Both the bound iron and total iron binding capacity of the plasma may be high (C) Only bound iron may be high (D) Only the total iron binding capacity may be high

Last Answer : Answer : A

Deficiency of iron in human diet causes (a) Goitre (b) Scurvy (c) Anaemia (d) Rickets

Description : Deficiency of iron in human diet causes (a) Goitre (b) Scurvy (c) Anaemia (d) Rickets

Last Answer : Ans:(c)

The deficiency of iron in man result in (1) Anaemia (2) Night, blindness (3) Scurvy (4) Rickets

Description : The deficiency of iron in man result in (1) Anaemia (2) Night, blindness (3) Scurvy (4) Rickets

Last Answer : (1) Anaemia Explanation: Anaemia is a condition in which the number of red blood cells or their oxygencarrying capacity is insufficient to meet physiologic needs, which vary by age, sex, altitude, ... , and pregnancy status. Iron deficiency is thought to be the most common cause of anaemia globally

Anaemia is caused because of deficiency of which of the following? (1) Cobalt (2) Iron (3) Sodium (4) Calcium

Description : Anaemia is caused because of deficiency of which of the following? (1) Cobalt (2) Iron (3) Sodium (4) Calcium

Last Answer : (2) Iron Explanation: Anemia is a condition that develops when blood lacks enough healthy red blood cells or hemoglobin. The three main types of anemia are due to blood loss, decreased red blood cell production, and increased red blood cell break down.

Which of the following is caused by a deficiency of iron in the diet? A. Giotre B. Scurvy C. Anaemia (Answer) D. Rickets

Description : Which of the following is caused by a deficiency of iron in the diet? A. Giotre B. Scurvy C. Anaemia (Answer) D. Rickets

Last Answer : C. Anaemia (Answer)

A patient of iron deficiency anaemia has been put on iron therapy. What should be the rate of rise in haemoglobin level of blood so that response is considered adequate: A. 0.05 – 0.1 g% per week B. 0.1 – 0.2 g% per week C. 0.5 – 1.0 g% per week D. More than 1.0 g% per week

Description : A patient of iron deficiency anaemia has been put on iron therapy. What should be the rate of rise in haemoglobin level of blood so that response is considered adequate: A. 0.05 – 0.1 g% per week B. 0.1 – 0.2 g% per week C. 0.5 – 1.0 g% per week D. More than 1.0 g% per week

Last Answer : C. 0.5 – 1.0 g% per week

Select the oral iron preparation which does not impart metallic taste and has good oral tolerability despite high iron content but whose efficacy in treating iron deficiency anaemia has been questioned: A. Iron hydroxy polymaltose B. Ferrous succinate C. Ferrous fumarate D. Ferrous gluconate

Description : Select the oral iron preparation which does not impart metallic taste and has good oral tolerability despite high iron content but whose efficacy in treating iron deficiency anaemia has been questioned: A. Iron hydroxy polymaltose B. Ferrous succinate C. Ferrous fumarate D. Ferrous gluconate

Last Answer : A. Iron hydroxy polymaltose

The deficiency of iron in man result in (1) Anaemia (2) Night blindness (3) Scurvy (4) Rickets

Description : The deficiency of iron in man result in (1) Anaemia (2) Night blindness (3) Scurvy (4) Rickets

Last Answer : Anaemia

Both sickle cell anaemia and Huntington’s chorea are (a) virus-related diseases (b) bacteria-related diseases (c) congenital disorders (d) pollutant-induced disorders.

Description : Both sickle cell anaemia and Huntington’s chorea are (a) virus-related diseases (b) bacteria-related diseases (c) congenital disorders (d) pollutant-induced disorders.

Last Answer : c) congenital disorders

Copper deficiency can cause (A) Polycythaemia (B) Leukocytopenia (C) Thrombocytopenia (D) Microcytic anaemia

Description : Copper deficiency can cause (A) Polycythaemia (B) Leukocytopenia (C) Thrombocytopenia (D) Microcytic anaemia

Last Answer : Answer : D

Biotin deficiency is characterized by the following except (A) Muscular pain (B) Anaemia (C) Nausea (D) Dermatitis

Description : Biotin deficiency is characterized by the following except (A) Muscular pain (B) Anaemia (C) Nausea (D) Dermatitis

Last Answer : Answer : B

The deficiency of Vitamin B12 leads to (A) Pernicious anaemia (B) Megablastic anaemia (C) Both (A) and (B) (D) None of these

Description : The deficiency of Vitamin B12 leads to (A) Pernicious anaemia (B) Megablastic anaemia (C) Both (A) and (B) (D) None of these

Last Answer : Answer : C

Anaemia can occur due to the deficiency of all the following except (A) Thiamin (B) Pyridoxine (C) Folic acid (D) Cyanocobalamin

Description : Anaemia can occur due to the deficiency of all the following except (A) Thiamin (B) Pyridoxine (C) Folic acid (D) Cyanocobalamin

Last Answer : Answer : A

Deficiency of vitamin C causes (A) Beriberi (B) Pellagra (C) Pernicious anaemia (D) Scurvy

Description : Deficiency of vitamin C causes (A) Beriberi (B) Pellagra (C) Pernicious anaemia (D) Scurvy

Last Answer : Answer : D

Serum LDL has been found to be increased in (A) Obstructive jaundice (B) Hepatic jaundice (C) Hemolytic jaundice (D) Malabsorption syndrome

Description : Serum LDL has been found to be increased in (A) Obstructive jaundice (B) Hepatic jaundice (C) Hemolytic jaundice (D) Malabsorption syndrome

Last Answer : Answer : A

The product of serum calcium concentration (mg/dl) and serum inorganic phosphorous concentration (mg/dl) is decreased in (A) Rickets (B) Hypoparathyroidism (C) Hyperparathyroidism (D) Renal failure

Description : The product of serum calcium concentration (mg/dl) and serum inorganic phosphorous concentration (mg/dl) is decreased in (A) Rickets (B) Hypoparathyroidism (C) Hyperparathyroidism (D) Renal failure

Last Answer : Answer : A

An inherited or acquired renal tubular defect in the reabsorption of phosphate (Vit D resistant ricket) is characterized with (A) Normal serum Phosphate (B) High serum phosphate (C) A low blood phosphorous with elevated alkaline Phosphate (D) A high blood phosphorous with decreased alkaline phosphatase

Description : An inherited or acquired renal tubular defect in the reabsorption of phosphate (Vit D resistant ricket) is characterized with (A) Normal serum Phosphate (B) High serum phosphate (C ... blood phosphorous with elevated alkaline Phosphate (D) A high blood phosphorous with decreased alkaline phosphatase

Last Answer : Answer : C

Hypolipidemic drugs reduce serum cholesterol and triacylglycerol. The effect of clofibrate is attributed to (A) Block in absorption from G.I.T. (B) Decrease in secretion of triacylglycerol and cholesterol containing VLDL by liver (C) Block in the reabsorption of bile acids (D) Decreased synthesis of cholesterol

Description : Hypolipidemic drugs reduce serum cholesterol and triacylglycerol. The effect of clofibrate is attributed to (A) Block in absorption from G.I.T. (B) Decrease in secretion of triacylglycerol and cholesterol ... by liver (C) Block in the reabsorption of bile acids (D) Decreased synthesis of cholesterol

Last Answer : Answer : B

Serum albumin may be decreased in (A) Haemolytic jaundice (B) Hepatocellular jaundice (C) Obstructive jaundice (D) All of these

Description : Serum albumin may be decreased in (A) Haemolytic jaundice (B) Hepatocellular jaundice (C) Obstructive jaundice (D) All of these

Last Answer : Answer : B

Serum cholesterol is decreased in (A) Endemic goitre (B) Thyrotoxicosis (C) Myxoedema (D) Cretinism

Description : Serum cholesterol is decreased in (A) Endemic goitre (B) Thyrotoxicosis (C) Myxoedema (D) Cretinism

Last Answer : B

Which of the following is true of Gilbert's syndrome? 1) inheritance is autosomal recessive 2) serum conjugated bilirubin levels are elevated 3) serum bilirubin levels are decreased by fasting 4) serum bilirubin levels are decreased by liver enzyme inducers 5) there is bilirubinuria

Description : Which of the following is true of Gilbert's syndrome? 1) inheritance is autosomal recessive 2) serum conjugated bilirubin levels are elevated 3) serum bilirubin levels are decreased by fasting 4) serum bilirubin levels are decreased by liver enzyme inducers 5) there is bilirubinuria

Last Answer : Answers-4 Gilbert's syndrome is inherited in autosomal dominant fashion and affects 2-5% of the population. UDP glucuronyl transferase levels are reduced leading to an unconjugated hyperbilirubinaemia. ... the bilirubin is reabsorbed in the proximal tubule some bilirubin is detectable in the urine.

A 16 year old male with a day history of malaise, weakness and vomiting. He was diagnosed with Insulin dependent diabetes mellitus 3 years prviously. Which ONE of the following supports a diagnosis of diabetic ketoacidosis: 1) Abdominal pain at onset 2) A serum bicarbonate of 10 mmol/l 3) A serum glucose 14 mmol/l 4) Decreased appetite in the past few days 5) Shallow respirations

Description : A 16 year old male with a day history of malaise, weakness and vomiting. He was diagnosed with Insulin dependent diabetes mellitus 3 years prviously. Which ONE of the following supports a diagnosis of ... serum glucose 14 mmol/l 4) Decreased appetite in the past few days 5) Shallow respirations

Last Answer : Answers-2 a-An unusual but recognised feature particularly in children. However does not support a diagnosis of DKA. b-Suggests metabolic acidosis. c-'Normoglycaemic DKA' can occur and a glucose ... anorexia. e-Respiratory compensation leads to rapid deep (Kussmaul's) breathing. (Dr Mike Mulcahy)

Clear organe solution of chromic anhydride in aqueous sulpuric acid turn blue-green on reaction with

Description : Clear organe solution of chromic anhydride in aqueous sulpuric acid turn blue-green on reaction with

Last Answer : Clear organe solution of chromic anhydride in aqueous sulpuric acid turn blue-green on reaction with A. ... 2-Methyl-2-propanol D. 2-Methyl-2-butanol

To obtain chromium from chromic oxide `(Cr_(3)O_(3))` the method used is

Description : To obtain chromium from chromic oxide `(Cr_(3)O_(3))` the method used is

Last Answer : To obtain chromium from chromic oxide `(Cr_(3)O_(3))` the method used is A. ... monoxide reduction C. Alumino thermic D. Electrolytic reduction

BMR is increased in all of the following except (A) Hyperthyroidism (B) Anaemia (C) Addison’s disease (D) Pregnancy

Description : BMR is increased in all of the following except (A) Hyperthyroidism (B) Anaemia (C) Addison’s disease (D) Pregnancy

Last Answer : Answer : C

The absorption of iron is increased 2–10 times of normal in (A) Iron deficiency anemia (B) Pregnancy (C) Spherocytosis (D) Sickle cell anemia

Description : The absorption of iron is increased 2–10 times of normal in (A) Iron deficiency anemia (B) Pregnancy (C) Spherocytosis (D) Sickle cell anemia

Last Answer : Answer : A