Which of the following statements concerning abnormalities of the haemoglobin molecule is true? 1) Alpha thalassaemia is due to a deficiency of beta-chain production 2) HbS is caused by a single base mutation on the beta-chain 3) genes for the alpha and beta chains are located on the same chromosome 4) in thalassaemia persistance of HbF is an adverse prognostic sign 5) oliguneoclitide probes may assist in the diagnosis of haemoglobinopathies

Which of the following statements concerning abnormalities of the haemoglobin molecule is true? 1) Alpha thalassaemia is due to a deficiency of beta-chain production 2) HbS is caused by a single base mutation on the beta-chain 3) genes for the alpha and beta chains are located on the same chromosome 4) in thalassaemia persistance of HbF is an adverse prognostic sign 5) oliguneoclitide probes may assist in the diagnosis of haemoglobinopathies
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Answers-2  Alpha Thalassaemia is due to abnormalities of the alpha chain. Persistence of HbF has survival advnatages in severely affected subjects. C-alpha 16, beta 11. e-Hb electrophoresis(Dr Shu Ho)
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If the amino group and a carboxylic group of the amino acid are attached to same carbon atom, the amino acid is called (A) Alpha (B) Beta (C) Gamma (D) Delta

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