Like all nuts, pistachios are high in fat and calories which makes many dieters avoid them, but they are also a rich source of monounsaturated fats and antioxidants that should be considered as part of any meal plan. Not only do they taste great, but pistachios have been found to help lower bad LDL cholesterol while raising good HDL cholesterol. Pistachios are high in vitamin E as well as minerals like copper, iron, and selenium. So, though they are high in calories, pistachios pack a powerful nutritional punch.