I apologize, I got on a roll and missed your other questions. The creams that you get at department stores are usually big on price, but deliver very little. Granted, these products have improved since their earlier days, but still not the same as a visit to a dermatologist. So, I not only want to help you feel better about your appearance, I want you to get the most out of every dollar you spend. The theory on Vitamin C is that it is an antioxidant that will slow the progression of wrinkles and promote collagen synthesis. However, Vitamin C is known to be unstable and can cause free radical formation itself, which causes cellular damage and aging. to be honest, I do not know of anyone that has tried Neu science, but from a quick look, it is another example of what I mentioned earlier. I am not sure that you would get the results that you desire. The collagen cream is good, but will take longer than injections and will not fully deliver what you want. Of what you listed, Resdermatrol is the best. It will help you, to a certain extent, and acts fairly quickly. If you are looking for one suggestion from me and do not want to make an appointment, get Resdermatrol. Again, I am sorry for missing your main question earlier. If you have any other questions, please ask.