DefinitionTricuspid regurgitation is a disorder in which the heart's tricuspid valve does not close properly, causing blood to flow backward (leak) into the right upper heart chamber (atrium) when the right lower heart chamber (ventricle) contracts.Alternative NamesTricuspid insufficiencyCauses, incidence, and risk factorsThe tricuspid valve separates the right lower heart chamber (the right ventricle) from the right upper heart chamber (right atrium).The most common cause of tricuspid regurgitation is swelling of the right ventricle. Such swelling may be a complication of any disorder that causes failure of the right ventricle.Tricuspid regurgitation may also be caused by or made worse by valve disease on the left side of the heart such as mitral regugitation and mitral stenosis.Other dis