DefinitionLeukocyte esterase is a urine test to look for white blood cells and other signs associated with infection.Alternative NamesWBC esteraseHow the test is performedA clean catch urine sample is needed. See: Urine specimen - clean catchHow to prepare for the testNo special preparation is necessary for this test.How the test will feelThe test will involve only normal urination, and there is no discomfort.Why the test is performedLeukocyte esterase is a screening test used to detect a substance that suggests there are white blood cells in the urine, which may mean you have a urinary tract infection.This test is part of the routine urine dipstick test. If this test is positive, the urine should be examined under a microscope for white blood cells and other abnormalities associated with