Description : Local anesthetics: A. Inhibit transmission of nerve impulses by increasing sodium membrane permeability and the displacement of ionized calcium. B. Are classified as amides or esters. C. Produce peripheral vasodilation. D. Are weak acids.
Last Answer : Answer: BC DISCUSSION: Local anesthetics act within the nerve membrane, where they inhibit transmission of nerve impulses by reducing sodium membrane permeability and the displacement of ionized ... based on this bond. All local anesthetics except cocaine produce vasodilatation and are weak bases
Description : When ammonia is added to an alkyl halide, in the presence of base : (a) primary amines form (b) amides form (c) nitrated alkyl halides form (d) quaternary ammonium salts form
Last Answer : primary amines form
Description : Which of the following reactions is suitable for the preparation of α-amino acids? (a) Schmidt reaction (b) Hofmann's degradation of amides (c) Strecker's synthesis (b) Reduction of nitro compounds
Last Answer : Strecker's synthesis
Description : Which of the following does not react with acyl chlorides to form amides : (a) ammonia (b) 1° amine (c) 2° amine (d) 3° amine
Last Answer : 3° amine
Description : Alkyl halides react with ammonia in the presence of base to form : (a) primary amines (b) nitrated alkyl halides (c) amides (d) quaternary ammonium salts
Last Answer : primary amines
Description : Which of the following statements is false about secondary amines? (a) They react with chloroform and NaOH to form isocyanides. (b) They can be prepared by reduction of isocyanides. (c) They react ... give substituted amides. (d) They react with ice-cold nitrous acid to give nitrosamine (yellow oil)
Last Answer : They react with chloroform and NaOH to form isocyanides.
Description : Amides undergo hydrolysis under acidic conditions to give (a) Carboxylic acid and amine (b) Carboxylic acid and ammonium ion (c) Carboxylate ion and ammonium ion (d) Carboxylate ion and amine
Last Answer : Carboxylic acid and ammonium ion
Description : Which of the following acid-derivatives are most stable? (a) Acid chlorides (b) Esters (c) Amides (d) Anhydrides
Last Answer : Amides
Description : Esters and amides are most easily made by nucleophilic acyl substitution reactions on : (a) acid anhydrides (b) carboxylates (c) carboxylic acids (d) acid chlorides
Last Answer : acid chlorides
Description : Amino acid synthesis inhibitors a). Sulfonyl ureas b). Amides c). Triazines d). all
Last Answer : a). Sulfonyl ureas