Description : Vasomotor reversal phenomenon after administration of an α adrenergic blocker is seen with: A. Adrenaline B. Noradrenaline C. Isoprenaline D. All of the above drugs
Last Answer : A. Adrenaline
Description : Prazosin is an effective antihypertensive while nonselective α adrenergic blockers are not because: A. It is the only orally active α blocker B. It improves plasma lipid profile C. It does not concurrently enhance noradrenaline release D. It improves urine flow in males with prostatic hypertrophy
Last Answer : C. It does not concurrently enhance noradrenaline release
Description : Rapid intravenous injection of clonidine causes rise in BP due to: A. Stimulation of vasomotor centre B. Release of noradrenaline from adrenergic nerve endings C. Agonistic action on vascular α2 adrenergic receptors D. Cardiac stimulation
Last Answer : C. Agonistic action on vascular α2 adrenergic receptors
Description : The following sympathomimetic amine has agonistic action on α 1 + α 2 + β 1 + β 3 adrenoceptors, but not on β 2 receptors: A. Adrenaline B. Noradrenaline C. Isoprenaline D. Phenylephrine
Last Answer : B. Noradrenaline
Description : Adrenergic neurone blocking drugs: A. Block the action of adrenaline on neuronal α2 adrenoceptors B. Block both α and β adrenoceptor mediated effects of injected adrenaline C. Do not block any effect of injected adrenaline D. Do not block the effects of sympathetic nerve
Last Answer : C. Do not block any effect of injected adrenaline
Description : Adrenergic neurone blocking drugs: A. Block the action of adrenaline on neuronal α2 adrenoceptors B. Block both α and β adrenoceptor mediated effects of injected adrenaline C. Do not block any effect of injected adrenaline D. Do not block the effects of sympathetic nerve stimulation
Description : Methyldopa lowers BP by: A. Inhibiting dopa decarboxylase in adrenergic nerve endings B. Generating α-methyl noradrenaline in brain which reduces sympathetic tone C. Generating α-methyl ... as a false transmitter in peripheral adrenergic nerve endings D. Activating vascular dopamine receptors
Last Answer : B. Generating α-methyl noradrenaline in brain which reduces sympathetic tone
Description : The drug which produces vasoconstriction despite being an α adrenergic blocker is: A. Phenoxybenzamine B. Ergotamine C. Dihydroergotoxine D. Tolazoline
Last Answer : B. Ergotamine
Description : The following sympathomimetic amine has agonistic action on α1 + α2 + β1 + β3 adrenoceptors, but not on β2 receptors: A. Adrenaline B. Noradrenaline C. Isoprenaline D. Phenylephrine
Description : While undergoing a surgical procedure a patient deve- lops hypotension. Which drug can be injected intramuscularly to raise his BP: A. Noradrenaline B. Isoprenaline C. Mephentermine D. Isoxsuprine
Last Answer : C. Mephentermine
Description : While undergoing a surgical procedure a patient develops hypotension. Which drug can be injected intramuscularly to raise his BP: A. Noradrenaline B. Isoprenaline C. Mephentermine D. Isoxsuprine
Description : Which of the following is a noncatecholamine sympathomimetic: A. Adrenaline B. Ephedrine C. Dopamine D. Isoprenaline
Last Answer : B. Ephedrine
Description : Prazosin is an effective antihypertensive while nonselective a adrenergic blockers are not because (a) It is the only orally active a blocker (b) It improves plasma lipid profile (c) It does not concurrently enhance noradrenaline release (d) It improves urine flow in males with prostatic hypertrophy
Last Answer : Ans: C
Description : The adrenergic tocolytic preferred for arresting labour is: A. Ritodrine B. Isoprenaline C. Salbutamol D. Terbutaline
Last Answer : A. Ritodrine
Description : While undergoing a surgical procedure a patient develops hypotension. Which of the following drugs can be injected intramuscularly to raise his BP (a) Noradrenaline (b) Isoprenaline (c) Mephentermine (d) Isoxsuprine
Description : The neuromuscular blocker that does not need reversal of action by neostigmine at the end of the operation is: A. d-Tubocurarine B. Doxacurium C. Pipecuronium D. Mivacurium
Last Answer : D. Mivacurium
Description : At the adrenergic synapse, the concentration of adrenaline in synaptic cleft: a. increased by cocaine which inhibit reuptake of adrenaline b. decreased by MAO (monoamine oxidase) - inhibitors c. controlled chiefly by the activity of the enzyme COMT d. increased by noradrenaline receptor blockers
Last Answer : increased by cocaine which inhibit reuptake of adrenaline
Description : The following is true of β-adrenergic blocker therapy in CHF: A. They are added to conventional therapy after cardiac compensation is restored B. They are indicated only in severe (NYHA class IV) heart failure C. They are to be used only at low doses D. All of the above
Last Answer : A. They are added to conventional therapy after cardiac compensation is restored
Description : The usual cardiovascular effect of levodopa is: A. Bradycardia due to increased vagal tone B. Rise in blood pressure due to increased noradrenaline content of adrenergic nerve endings C. Fall in blood pressure due to decrease in sympathetic tone D. Both ‘A’ and ‘B’ are correct
Last Answer : C. Fall in blood pressure due to decrease in sympathetic tone
Description : The principal process which terminates the action of noradrenaline released from adrenergic nerve ending is: A. Degradation by MAO B. Methylation by COMT C. Axonal uptake D. Extraneuronal uptake
Last Answer : C. Axonal uptake
Description : Tyramine induces release of noradrenaline from adrenergic nerve endings: A. By depolarizing the axonal membrane B. By mobilizing Ca2+ C. By a nonexocytotic process D. Only in the presence of MAO inhibitors
Last Answer : C. By a nonexocytotic process
Description : The following is true of propafenone except: A. It is a weak Na+ channel blocker B. It markedly delays recovery of myocardial Na+ channels C. It has additional β-adrenergic blocking property D. It slows anterograde as well as retrograde conduction in the WPW bypass tract
Last Answer : A. It is a weak Na+ channel blocker
Description : The primary reason for preferring phentolamine as the α adrenergic blocker for performing diagnostic test for pheochromocytoma is: A. It produces rapid and short lasting α-adrenergic blockade B. It equally ... It is the most potent α blocker D. It has no additional β adrenergic blocking property
Last Answer : A. It produces rapid and short lasting α-adrenergic blockade
Description : Dihydroergotamine (DHE) differs from ergotamine in the following respect: A. It is a more potent oxytocic B. It has antiemetic property C. It has high oral bioavailability D. It is a more potent α adrenergic blocker and less potent vasoconstrictor
Last Answer : D. It is a more potent α adrenergic blocker and less potent vasoconstrictor
Description : Select the β -adrenergic blocker that has additional α 1 blocking, vasodilator and antioxidant properties: A. Carvedilol B. Celiprolol C. Acebutolol D. Metoprolol
Last Answer : A. Carvedilol
Description : Adrenaline is inactive orally because it is: A. Not absorbed from the gastrointestinal tract B. Destroyed by gastric acid C. Completely metabolized in the intestinal mucosa and liver before reaching systemic circulation D. Taken up by adrenergic nerve endings of the intestinal wall, liver and lungs
Last Answer : C. Completely metabolized in the intestinal mucosa and liver before reaching systemic circulation
Description : Ephedrine is similar to adrenaline in the following feature: A. Potency B. Inability to penetrate blood-brain barrier C. Duration of action D. Producing both α and β adrenergic effects
Last Answer : D. Producing both α and β adrenergic effects
Description : Choose the correct statement about latanoprost: A. It is a PGF2α derivative used in glaucoma B. It is a selective α1 blocker used in benign hypertrophy of prostate C. It is a 5-α- ... reduce the size of enlarged prostate gland D. It is a PGE2 analogue used intravaginally for cervical priming
Last Answer : A. It is a PGF2α derivative used in glaucoma
Description : A sympathomimetic amine that acts almost exclusively by releasing noradrenaline from the nerve endings is (a) Ephedrine (b) Dopamine (c) Isoprenaline (d) Tyramine
Last Answer : Ans: D
Description : A sympathomimetic amine that acts almost exclusively by releasing noradrenaline from the nerve endings is: A. Ephedrine B. Dopamine C. Isoprenaline D. Tyramine
Last Answer : D. Tyramine
Description : Adrenaline raises blood glucose level by the following actions except: A. Inducing hepatic glycogenolysis B. Inhibiting insulin secretion from pancreatic β cells C. Augmenting glucagon secretion from pancreatic α cells D. Inhibiting peripheral glucose utilization
Last Answer : D. Inhibiting peripheral glucose utilization
Description : A patient has an episode of hematemesis following streptokinase infused for the treatment of deep vein thrombosis. Which of the following drugs would be most effective in controlling the bleeding episode: A. Vitamin K B. Noradrenaline C. Epsilon aminocaproic acid D. Rutin
Last Answer : C. Epsilon aminocaproic acid
Description : Procainamide differs from quinidine in the following respect(s): A. It does not cause paradoxical tachycardia B. It has no α adrenergic blocking activity C. It has little antivagal action D. Both ‘B’ and ‘C’ are corre
Last Answer : D. Both ‘B’ and ‘C’ are correct
Description : Procainamide differs from quinidine in the following respect(s): A. It does not cause paradoxical tachycardia B. It has no α adrenergic blocking activity C. It has little antivagal action D. Both ‘B’ and ‘C’ are correct
Description : The following drug claimed to have a therapeutic effect in senile dementia has α adrenergic blocking activity: A. Piracetam B. Pyritinol C. Codergocrine D. Methylphenidate
Last Answer : C. Codergocrine
Description : 6.12 The most prominent action of bromocriptine is: A. Dopamine D2 agonism B. Dopamine D2 antagonism C. Dopamine D1 antagonism D. α adrenergic antagonism
Last Answer : A. Dopamine D2 agonism
Description : Labetalol has: A. More potent β adrenergic blocking than α blocking activity B. More potent α adrenergic blocking than β blocking activity C. Equal α and β adrenergic blocking activity D. β1 agonistic activity in addition to α and β adrenergic blockade
Last Answer : A. More potent β adrenergic blocking than α blocking activity
Description : Ergotamine relieves migraine by: A. Blocking vascular α adrenergic receptors B. Blocking vascular 5-HT2 receptors C. Dilating cranial arterio-venous shunt channels D. Constricting cranial vessels and reducing perivascular neurogenic inflammation
Last Answer : D. Constricting cranial vessels and reducing perivascular neurogenic inflammation
Description : The nonselective α adrenergic blockers produce the following actions except: A. Postural hypotension B. Bradycardia C. Miosis D. Inhibition of ejaculation
Last Answer : B. Bradycardia
Description : The α 2 adrenoceptors are: A. Located exclusively on the adrenergic nerve endings B. Prejunctional, postjunctional as well as extrajunctional in location C. Selectively activated by phenylephrine D. Selectively blocked by clonidine
Last Answer : B. Prejunctional, postjunctional as well as extrajunctional in location