The following is true of clofazimine except:
A. It is cidal to Mycobacterium leprae
B. It has additional antiinflammatory property
C. It has a very long elimination half life
D. It discolours skin and sweat

1 Answer

Answer :

A. It is cidal to Mycobacterium leprae

Related questions

Description : : All the following are among the opportunistic organisms that may cause nosocomial disease except: a. Pseudomonas aeruginosa. b. Escherichia coli. c. Staphylococcus aureus. d. Mycobacterium leprae.

Last Answer : d. Mycobacterium leprae.

Description : Antiatherosclerotic effect of which class of hypolipidemic drugs may involve additional mechanisms like improved endothelial function, reduced LDL oxidation and antiinflammatory property: A. Bile acid sequestrant resins B. Statins C. Fibrates D. Nicotinic acid

Last Answer : B. Statins

Description : The distinctive features of azithromycin include the following except: A. Efficacy against organisms which have developed resistance to erythromycin B. Marked tissue distribution and intracellular penetration ... D. Low propensity to drug interactions due to inhibition of cytochrome P450 enzymes

Last Answer : A. Efficacy against organisms which have developed resistance to erythromycin

Description : Mycobacterium leprae is a - (1) Bacillus (2) Coccus (3) Spiral (4) Spore

Last Answer : (1) Bacillus Explanation: Mycobacterium leprae is a bacillus.

Description : Mycobacterium leprae causes leprosy; Corynebacterium diphtheria causes diphthe- ria and Vibrio comma causes?

Last Answer : cholera.

Description : Which is showing accurate pairing? (a) Syphilis - Treponema pallidum (b) AIDS - Bacillus conjugalis (c) Gonorrhoea - Leishmania donovani (d) Typhoid - Mycobacterium leprae

Last Answer : (a) Syphilis - Treponema pallidum

Description : Mycobacterium leprae is a (1) Bacillus (2) Coccus (3) Spiral (4) Spore

Last Answer : Bacillus

Description : The following is true of propafenone except: A. It is a weak Na+ channel blocker B. It markedly delays recovery of myocardial Na+ channels C. It has additional β-adrenergic blocking property D. It slows anterograde as well as retrograde conduction in the WPW bypass tract

Last Answer : A. It is a weak Na+ channel blocker

Description : The plasma half life of aspirin (along with salicylic acid released from it): A. Remains constant irrespective of dose B. Is longer for antiinflammatory doses compared to that for analgesic ... for antiinflammatory doses compared to that for analgesic dose D. Can be shortened by acidifying urine

Last Answer : B. Is longer for antiinflammatory doses compared to that for analgesic dose

Description : Which antileprotic drug suppresses lepra reaction and reversal reaction as well: A. Dapsone B. Rifampin C. Clofazimine D. Minocycline

Last Answer : C. Clofazimine

Description : If a multibacillary leprosy patient treated with standard fixed duration multidrug therapy relapses, he should be treated with: A. The same rifampin + dapsone + clofazimine regimen B. ... + minocycline C. Clofazimine + ofloxacin + clarithromycin D. Ofloxacin + minocycline + clarithromycin

Last Answer : . The same rifampin + dapsone + clofazimine regimen

Description : The following is true of quinine: A. It has a longer elimination half-life than chloroquine B. It is not to be used for prophylaxis of malaria C. It is not active against P. vivax D. It should not be used along with sulfa-pyrimethamine

Last Answer : B. It is not to be used for prophylaxis of malaria

Description : Choose the correct statement about nonopioid analgesics: A. All have antiinflammatory property B. All lack dependence producing liability C. All act exclusively at peripheral pain mechanisms D. All inhibit prostaglandin synthesis

Last Answer : B. All lack dependence producing liability

Description : Teicoplanin has the following feature(s): A. Antimicrobial activity and indications similar to vancomycin B. Long elimination half-life C. Efficacy in systemic infections by oral route D. Both ‘A’ and ‘B’ are correct

Last Answer : D. Both ‘A’ and ‘B’ are correct

Description : Which of the following is not an attribute of amlodipine: A. Generation of an active metabolite B. Large volume of distribution C. High and consistent oral bioavailability D. Long elimination half life

Last Answer : A. Generation of an active metabolit

Description : Advantages of angiotensin converting enzyme inhibitors as antihypertensive include the following except: A. They tend to reverse left ventricular hypertrophy B. Their efficacy is not reduced by nonsteroidal ... . They do not worsen blood lipid profile D. They do not impair work performance

Last Answer : B. Their efficacy is not reduced by nonsteroidal antiinflammatory drugs

Description : The constellation of adverse effects associated with nonsteroidal antiinflammatory drugs include the following except: A. Sedation B. Gastric irritation C. Fluid retention D. Rashes

Last Answer : A. Sedation

Description : Metabolic effects that generally attend antiinflammatory doses of aspirin include the following except: A. Increased CO2 production B. Hepatic glycogen depletion C. Metabolic acidosis D. Compensated respiratory alkalosis

Last Answer : C. Metabolic acidosis

Description : The following is true of clarithromycin except: A. It produces less gastric irritation and pain than erythromycin B. It is the most active macrolide antibiotic against Helicobacter pylori ... terfenadine or cisapride to cause cardiac arrhythmias D. It exhibits dose dependent elimination kinetics

Last Answer : C. It does not interact with terfenadine or cisapride to cause cardiac arrhythmias

Description : Which fluoroquinolone is highly active against Mycobact. leprae and is being used in alternative multidrug therapy regimens: A. Norfloxacin B. Ofloxacin C. Ciprofloxacin D. Lomefloxacin

Last Answer : B. Ofloxacin

Description : Tinidazole differs from metronidazole in that: A. It is not active against anaerobic bacteria B. It has a broader spectrum of activity C. It has a longer elimination half life D. It has better oral absorption

Last Answer : C. It has a longer elimination half life

Description : Select the fluoroquinolone which has high oral bioavailability, longer elimination half-life and which does not inhibit metabolism of theophylline: A. Norfloxacin B. Pefloxacin C. Lomefloxacin D. Ciprofloxacin

Last Answer : C. Lomefloxacin

Description : Compared to pork/beef insulins, the human insulins: A. Are more potent B. Have a faster kinetics of absorption and elimination C. Have longer biological action half life D. Penetrate blood-brain barrier more efficiently

Last Answer : B. Have a faster kinetics of absorption and elimination

Description : If a drug is eliminated by first order kinetics: A. A constant amount of the drug will be eliminated per unit time B. Its clearance value will remain constant C. Its elimination half life will increase with dose D. It will be completely eliminated from the body in 2 × half life period

Last Answer : B. Its clearance value will remain constant

Description : What is true of nimesulide: A. It exerts antiinflammatory action by several mechanisms in addition to cyclooxygenase inhibition B. It is preferred for long-term use in rheumatoid arthritis C. It is contraindicated in aspirin intolerant asthma patients D. All of the above

Last Answer : A. It exerts antiinflammatory action by several mechanisms in addition to cyclooxygenase inhibition

Description : Antimicrobial drug combinations are aimed at achieving the following except: A. Faster and more complete elimination of the infecting organism B. Treat infection when nature and sensitivity of the infecting organism is not definite C. Prevent emergence of resistant strains D. Prevent superinfection

Last Answer : D. Prevent superinfection

Description : The general principles in the use of hypnotics include the following except: A. A hypnotic may be used intermittently for upto 2-3 weeks in short-term insomnia due to emotional stress B ... sleep apnoea D. A hypnotic with slow elimination is preferred in patients with early morning awakening

Last Answer : B. In patients with chronic insomnia a hypnotic should be used regularl

Description : The following is/are true of mesalazine: A. It exerts mainly local antiinflammatory action in the lower gut B. It is a broad spectrum antidiarrhoeal drug C. It can be administered as a retention enema D. Both 'A' and 'C

Last Answer : D. Both 'A' and 'C

Description : The following statement is true about misoprostol: A. It relieves peptic ulcer pain, but does not promote ulcer healing B. It heals nonsteroidal antiinflammatory drug induced gastric ulcer not responding ... side effects than H2 blockers D. It is the most effective drug for preventing ulcer relapse

Last Answer : B. It heals nonsteroidal antiinflammatory drug induced gastric ulcer not responding to H2 blockers

Description : The following is true of procainamide except: A. It generates an active metabolite in the body B. Its plasma half-life is longer than that of quinidine C. On long-term use, it ... erythematosus like illness D. It is effective in many cases of ventricular extrasystoles, not responding to lignocaine

Last Answer : A. Disopyramide

Description : additional mild antidepressant property: A. Chlordiazepoxide B. Oxazepam C. Alprazolam D. Lorazepa

Last Answer : C. Alprazolam

Description : Labetalol differs from propranolol in that: A. It has additional α1 blocking property B. It is a selective β1 blocker C. It does not undergo first pass metabolism D. All of the above

Last Answer : A. It has additional α1 blocking property

Description : Labetalol differs from propranolol in that: A. It has additional α1 blocking property B. It is a selective β1 blocker C. It does not undergo first pass metabolism D. All of the above

Last Answer : A. It has additional α1 blocking property

Description : The following antibiotic is a first line drug for treatment of Mycobacterium avium complex infection in AIDS patients: A. Clindamycin B. Clarithromycin C. Roxithromycin D. Erythromycin

Last Answer : B. Clarithromycin

Description : The following apply to use of spironolactone in CHF except: A. It is indicated only in NYHA class III/IV cases as additional drug to conventional therapy B. It affords prognostic benefit in ... by ACE inhibitors C. It helps overcome refractoriness to diuretics D. It affords rapid symptomatic relief

Last Answer : D. It affords rapid symptomatic relief

Description : The distinctive features of desogestrel include the following except: A. It is a prodrug B. It has both strong progestational and strong antiovulatory activities C. It has additional androgenic acitivity D. It does not counteract the beneficial effect of estrogen on lipid profile

Last Answer : C. It has additional androgenic acitivity

Description : he distinctive features of desogestrel include the following except: A. It is a prodrug B. It has both strong progestational and strong antiovulatory activities C. It has additional androgenic acitivity D. It does not counteract the beneficial effect of estrogen on lipid profile

Last Answer : C. It has additional androgenic acitivity

Description : Nonsteroidal antiinflammatory drugs reduce the diuretic action of furosemide by: A. Preventing prostaglandin mediated intrarenal haemodynamic actions B. Blocking the action in ascending limb of loop ... C. Enhancing salt and water reabsorption in distal tubule D. Increasing aldosterone secretion

Last Answer : A. Preventing prostaglandin mediated intrarenal haemodynamic actions

Description : The most important mechanism of antiinflammatory action of glucocorticoids is: A. Inhibition of lysosomal enzymes B. Restriction of recruitment of inflammatory cells at the site of inflammation C. Antagonism of action of interleukins D. Suppression of complement function

Last Answer : B. Restriction of recruitment of inflammatory cells at the site of inflammation

Description : Corticosteroids exert antiinflammatory action by inhibiting the following enzyme: A. Cyclooxygenase B. Lipoxygenase C. Phospholipase-A D. Phosphodiesterase

Last Answer : C. Phospholipase-A

Description : Budesonide is a: A. Nonsteroidal antiinflammatory drug B. High ceiling diuretic C. Inhaled corticosteroid for asthma D. Contraceptive

Last Answer : C. Inhaled corticosteroid for asthma

Description : Select the drug that is neither bronchodilator nor antiinflammatory, but has antihistaminic and mast cell stabilizing activity: A. Sodium cromoglycate B. Ketotifen C. Beclomethasone dipropionate D. Chlorpheniramine

Last Answer : B. Ketotifen

Description : Sulfinpyrazone has the following action(s): A. Antiplatelet aggregatory B. Uricosuric C. Antiinflammatory D. Both ‘A’ and ‘B’

Last Answer : D. Both ‘A’ and ‘B’

Description : The following antiinflammatory analgesic has been cleared for pediatric use: A. Indomethacin B. Ibuprofen C. Ketorolac D. Piroxicam

Last Answer : B. Ibuprofen

Description : Choose the correct statement about nefopam: A. It is a nonopioid analgesic which does not inhibit prostaglandin synthesis B. It is an orally active opioid analgesic C. It is an analgesic with potent antiinflammatory activity D. It is a preferential COX-2 inhibitor

Last Answer : A. It is a nonopioid analgesic which does not inhibit prostaglandin synthesis

Description : Which of the following is an efficacious antiinflammatory drug but a relatively weak inhibitor of cyclooxygenase: A. Nimesulide B. Paracetamol C. Ketoprofen D. Indomethacin

Last Answer : A. Nimesulide

Description : The following nonsteroidal antiinflammatory drug is a preferential cyclooxygenase-2 (COX-2) inhibitor: A. Tenoxicam B. Meloxicam C. Diclofenac sod. D. Ketoprofen

Last Answer : B. Meloxicam

Description : Which analgesic-antiinflammatory drug is more appropriate in musculo-skeletal disorder where pain is more prominent than inflammation: A. Ibuprofen B. Piroxicam C. Indomethacin D. Nimesulide

Last Answer : A. Ibuprofen

Description : Choose the correct statement about nonsteroidal antiinflammatory drugs (NSAIDs): A. NSAIDs attenuate hypoglycaemic action of sulfonylureas B. NSAIDs potentiate antihypertensive action of ACE inhibitors C. ... D. Combined therapy with prednisolone and NSAIDs carries higher risk of gastric bleeding

Last Answer : D. Combined therapy with prednisolone and NSAIDs carries higher risk of gastric bleeding

Description : Choose the action for which the dose of aspirin required is the lowest: A. Analgesic B. Antipyretic C. Antiinflammatory D. Antiplatelet aggregatory

Last Answer : D. Antiplatelet aggregatory