Choose the correct statement about nonsteroidal antiinflammatory drugs (NSAIDs): A. NSAIDs attenuate hypoglycaemic action of sulfonylureas B. NSAIDs potentiate antihypertensive action of ACE inhibitors C. Serum lithium levels are lowered by concurrent administration of NSAIDs D. Combined therapy with prednisolone and NSAIDs carries higher risk of gastric bleeding

Choose the correct statement about nonsteroidal antiinflammatory drugs (NSAIDs): A. NSAIDs attenuate hypoglycaemic action of sulfonylureas B. NSAIDs potentiate antihypertensive action of ACE inhibitors C. Serum lithium levels are lowered by concurrent administration of NSAIDs D. Combined therapy with prednisolone and NSAIDs carries higher risk of gastric bleeding
by

1 Answer

Answer :

D. Combined therapy with prednisolone and NSAIDs carries higher risk of gastric bleeding
by

Related questions

The hypoglycaemic action of sulfonylureas is likely to be attenuated by the concurrent use of: A. Hydrochlorothiazide B. Propranolol C. Theophylline D. Aspirin

Description : The hypoglycaemic action of sulfonylureas is likely to be attenuated by the concurrent use of: A. Hydrochlorothiazide B. Propranolol C. Theophylline D. Aspirin

Last Answer : A. Hydrochlorothiazide

Three medications referred to as the ‘ABC drugs’ are currently the main pharmacological therapy for multiple sclerosis. Which of the following statements reflects information to be included in patient teaching? a) Flu-like symptoms can be controlled with nonsteroidal antiinflammatory drugs (NSAIDs) and usually resolve after a few months of therapy. Seventy-five percent of patients taking one of the interferons experience flu-like symptoms that can be controlled with NSAIDS and usually resolve after a few months of therapy.

Description : Three medications referred to as the ABC drugs' are currently the main pharmacological therapy for multiple sclerosis. Which of the following statements reflects information to be included in patient ... on an empty stomach. Glatiramer acetate is administed by intramuscular injection once a week.

Last Answer : a) Flu-like symptoms can be controlled with nonsteroidal antiinflammatory drugs (NSAIDs) and usually resolve after a few months of therapy. Seventy-five percent of patients taking one of the ... symptoms that can be controlled with NSAIDS and usually resolve after a few months of therapy.

Advantages of angiotensin converting enzyme inhibitors as antihypertensive include the following except: A. They tend to reverse left ventricular hypertrophy B. Their efficacy is not reduced by nonsteroidal antiinflammatory drugs C. They do not worsen blood lipid profile D. They do not impair work performance

Description : Advantages of angiotensin converting enzyme inhibitors as antihypertensive include the following except: A. They tend to reverse left ventricular hypertrophy B. Their efficacy is not reduced by nonsteroidal ... . They do not worsen blood lipid profile D. They do not impair work performance

Last Answer : B. Their efficacy is not reduced by nonsteroidal antiinflammatory drugs

Phenylbutazone should be used only in patients not responding to other nonsteroidal antiinflammatory drugs (NSAIDs) because: A. It has lower antiinflammatory efficacy than other NSAIDs B. It has potential to cause agranulocytosis C. It has weak analgesic action D. It alters the protein binding and metabolism of many drugs

Description : Phenylbutazone should be used only in patients not responding to other nonsteroidal antiinflammatory drugs (NSAIDs) because: A. It has lower antiinflammatory efficacy than other NSAIDs B. It has potential ... It has weak analgesic action D. It alters the protein binding and metabolism of many drugs

Last Answer : B. It has potential to cause agranulocytosis

The nonsteroidal antiinflammatory drugs are more effective in migraine: A. Without aura B. With aura C. Than ergotamine D. When combined with propranolol

Description : The nonsteroidal antiinflammatory drugs are more effective in migraine: A. Without aura B. With aura C. Than ergotamine D. When combined with propranolol

Last Answer : A. Without aura

The constellation of adverse effects associated with nonsteroidal antiinflammatory drugs include the following except: A. Sedation B. Gastric irritation C. Fluid retention D. Rashes

Description : The constellation of adverse effects associated with nonsteroidal antiinflammatory drugs include the following except: A. Sedation B. Gastric irritation C. Fluid retention D. Rashes

Last Answer : A. Sedation

Monitoring plasma drug concentration is useful while using: A. Antihypertensive drugs B. Levodopa C. Lithium carbonate D. MAO inhibitors

Description : Monitoring plasma drug concentration is useful while using: A. Antihypertensive drugs B. Levodopa C. Lithium carbonate D. MAO inhibitors

Last Answer : C. Lithium carbonate

Choose the correct statement about use of βadrenergic blockers in CHF: A. All β blockers are equally effective in CHF B. They are used as alternative to conventional therapy with ACE inhibitors ± digitalis/ diuretic C. They are most useful in mild to moderate cases with systolic dysfunction due to dilated cardiomyopathy D. They are indicated only in asymptomatic left ventricular dysfunction

Description : Choose the correct statement about use of βadrenergic blockers in CHF: A. All β blockers are equally effective in CHF B. They are used as alternative to conventional therapy with ... dysfunction due to dilated cardiomyopathy D. They are indicated only in asymptomatic left ventricular dysfunction

Last Answer : C. They are most useful in mild to moderate cases with systolic dysfunction due to dilated cardiomyopathy

Nonsteroidal antiinflammatory drugs reduce the diuretic action of furosemide by: A. Preventing prostaglandin mediated intrarenal haemodynamic actions B. Blocking the action in ascending limb of loop of Henle. C. Enhancing salt and water reabsorption in distal tubule D. Increasing aldosterone secretion

Description : Nonsteroidal antiinflammatory drugs reduce the diuretic action of furosemide by: A. Preventing prostaglandin mediated intrarenal haemodynamic actions B. Blocking the action in ascending limb of loop ... C. Enhancing salt and water reabsorption in distal tubule D. Increasing aldosterone secretion

Last Answer : A. Preventing prostaglandin mediated intrarenal haemodynamic actions

The following statement is true about misoprostol: A. It relieves peptic ulcer pain, but does not promote ulcer healing B. It heals nonsteroidal antiinflammatory drug induced gastric ulcer not responding to H2 blockers C. It produces fewer side effects than H2 blockers D. It is the most effective drug for preventing ulcer relapse

Description : The following statement is true about misoprostol: A. It relieves peptic ulcer pain, but does not promote ulcer healing B. It heals nonsteroidal antiinflammatory drug induced gastric ulcer not responding ... side effects than H2 blockers D. It is the most effective drug for preventing ulcer relapse

Last Answer : B. It heals nonsteroidal antiinflammatory drug induced gastric ulcer not responding to H2 blockers

Choose the correct statement about use of gold sod. thiomalate in rheumatoid arthritis: A. It affords more rapid symptomatic relief than NSAIDs B. The NSAIDs therapy is discontinued when it is started C. It is used as an alternative to corticosteroids D. It is used only in severe cases when other diseases modifying antirheumatic drugs have failed

Description : Choose the correct statement about use of gold sod. thiomalate in rheumatoid arthritis: A. It affords more rapid symptomatic relief than NSAIDs B. The NSAIDs therapy is discontinued when it is ... D. It is used only in severe cases when other diseases modifying antirheumatic drugs have failed

Last Answer : D. It is used only in severe cases when other diseases modifying antirheumatic drugs have failed

Select the correct statement about combining antihypertensive drugs: A. Antihypertensive combinations should always be preferred over single drugs B. Combinations of antihypertensives with similar pattern of haemodynamic action are superior to those with dissimilar pattern C. Antihypertensives which act on different regulatory systems maintaining blood pressure should be combined D. A diuretic must be included whenever antihypertensives are combined

Description : Select the correct statement about combining antihypertensive drugs: A. Antihypertensive combinations should always be preferred over single drugs B. Combinations of antihypertensives with similar ... should be combined D. A diuretic must be included whenever antihypertensives are combined

Last Answer : C. Antihypertensives which act on different regulatory systems maintaining blood pressure should be combined

___________ antihypertensive therapy should be avoided in type-1 diabetes mellitus a) ACE inhibitors b) High dose diuretics c) Centrally acting d) calcium channel blockers

Description : ___________ antihypertensive therapy should be avoided in type-1 diabetes mellitus a) ACE inhibitors b) High dose diuretics c) Centrally acting d) calcium channel blockers

Last Answer : c) Centrally acting  

Choose the correct statement about amantadine: A. It is an antimetabolite used for viral infections B. It prevents penetration of the virus into the host cell C. It is used to protect high risk subjects during an influenza A2 epidemic D. Concurrent administration of amantadine prevents antibody response to influenza vaccine

Description : Choose the correct statement about amantadine: A. It is an antimetabolite used for viral infections B. It prevents penetration of the virus into the host cell C. It is used ... during an influenza A2 epidemic D. Concurrent administration of amantadine prevents antibody response to influenza vaccine

Last Answer : C. It is used to protect high risk subjects during an influenza A2 epidemic

True statements regarding eicosanoids include which of the following? A. Prostaglandins and thromboxanes are synthesized via the cyclo-oxygenase pathway. B. The vasoconstricting, platelet-aggregating, and bronchoconstricting effects of thromboxane A 2 are balanced by the actions of prostacyclin, which produces the opposite effects. C. Leukotriene synthesis is inhibited by the action of nonsteroidal anti-inflammatory drugs (NSAIDs). D. The principal prostaglandins have a short circulation half-life and exert most of their effects locally.

Description : True statements regarding eicosanoids include which of the following? A. Prostaglandins and thromboxanes are synthesized via the cyclo-oxygenase pathway. B. The vasoconstricting, platelet-aggregating, ... prostaglandins have a short circulation half-life and exert most of their effects locally.

Last Answer : Answer: ABD DISCUSSION: The eicosanoids are a group of compounds arising from the metabolism of arachidonic acid. The prostaglandins and thromboxanes are synthesized via the cyclo-oxygenase ... effects and may be involved in the physiologic responses associated with anaphylactic and septic shock

Monitoring plasma drug concentration is useful while using: A. Antihypertensive drugs B. Levodopa C. Lithium carbonate D. MAO inhibitors

Description : Monitoring plasma drug concentration is useful while using: A. Antihypertensive drugs B. Levodopa C. Lithium carbonate D. MAO inhibitors

Last Answer : C. Lithium carbonate

Choose the correct statement about carbimazole: A. It induces improvement in thyrotoxic symptoms afer 1-4 weeks therapy B. Control of thyrotoxic symptoms with carbimazole is accompanied by enlargement of thyroid gland C. Its long term use in Grave's disease leads to ‘thyroid escape’ D. It mitigates thyrotoxic symptoms without lowering serum thyroxine levels

Description : Choose the correct statement about carbimazole: A. It induces improvement in thyrotoxic symptoms afer 1-4 weeks therapy B. Control of thyrotoxic symptoms with carbimazole is accompanied by ... leads to thyroid escape' D. It mitigates thyrotoxic symptoms without lowering serum thyroxine levels

Last Answer : A. It induces improvement in thyrotoxic symptoms afer 1-4 weeks therap

Nonsteroidal antiinflammatory drugs are more commonly used than colchicine in acute gout because: A. They are more effective B. They act more rapidly C. They have additional uricosuric action D. They are better tolerated

Description : Nonsteroidal antiinflammatory drugs are more commonly used than colchicine in acute gout because: A. They are more effective B. They act more rapidly C. They have additional uricosuric action D. They are better tolerated

Last Answer : D. They are better tolerated

The following apply to use of spironolactone in CHF except: A. It is indicated only in NYHA class III/IV cases as additional drug to conventional therapy B. It affords prognostic benefit in severe heart failure over and above that afforded by ACE inhibitors C. It helps overcome refractoriness to diuretics D. It affords rapid symptomatic relief

Description : The following apply to use of spironolactone in CHF except: A. It is indicated only in NYHA class III/IV cases as additional drug to conventional therapy B. It affords prognostic benefit in ... by ACE inhibitors C. It helps overcome refractoriness to diuretics D. It affords rapid symptomatic relief

Last Answer : D. It affords rapid symptomatic relief

The following measure can minimise pituitary-adrenal suppression during long-term corticosteroid therapy: A. Use of betamethasone in place of prednisolone B. Use of prednisolone on alternate days C. Division of the daily dose in three equal 8 hourly doses D. Administration of the total daily dose at bed time

Description : The following measure can minimise pituitary-adrenal suppression during long-term corticosteroid therapy: A. Use of betamethasone in place of prednisolone B. Use of prednisolone on alternate days C. Division of ... in three equal 8 hourly doses D. Administration of the total daily dose at bed time

Last Answer : B. Use of prednisolone on alternate days

In a patient of diabetes mellitus maintained on insulin therapy, administration of the following drug can vitiate glycaemia control: A. Prednisolone B. Prazosin C. Paracetamol D. Phenytoin

Description : In a patient of diabetes mellitus maintained on insulin therapy, administration of the following drug can vitiate glycaemia control: A. Prednisolone B. Prazosin C. Paracetamol D. Phenytoin

Last Answer : A. Prednisolone

Which racial difference in response to drugs has been mentioned incorrectly below: A. Africans require higher concentration of atropine to dilate pupils B. Black races are more responsive to antihypertensive action of beta blockers C. Japanese are more prone to develop SMON due to halogenated hydroxyquinolines D. Chloramphenicol induced aplastic anaemia is rare among Indians

Description : Which racial difference in response to drugs has been mentioned incorrectly below: A. Africans require higher concentration of atropine to dilate pupils B. Black races are more responsive ... SMON due to halogenated hydroxyquinolines D. Chloramphenicol induced aplastic anaemia is rare among Indians

Last Answer : B. Black races are more responsive to antihypertensive action of beta blockers

Thiazide diuretics do not potentiate the antihypertensive action of one of the following drugs: A. Metoprolol B. Nifedipine C. Hydralazine D. Captopril

Description : Thiazide diuretics do not potentiate the antihypertensive action of one of the following drugs: A. Metoprolol B. Nifedipine C. Hydralazine D. Captopril

Last Answer : B. Nifedipine

Patients taking chronic doses of nonselective nonsteroidal anti-inflammatory drugs (NSAIDs) should periodically be screened for which of the following toxicities? (a) Nephrotoxicity (b) Peripheral neuropathy (c) Cardiotoxicity (d) All of the above (e) None of the above

Description : Patients taking chronic doses of nonselective nonsteroidal anti-inflammatory drugs (NSAIDs) should periodically be screened for which of the following toxicities? (a) Nephrotoxicity (b) Peripheral neuropathy (c) Cardiotoxicity (d) All of the above (e) None of the above

Last Answer : Ans: A

Of the following classifications of medications, which is known to inhibit prostaglandin synthesis or release? a) Nonsteroidal anti-inflammatory drugs (NSAIDs) in large doses NSAIDs include aspirin and ibuprofen.

Description : Of the following classifications of medications, which is known to inhibit prostaglandin synthesis or release? a) Nonsteroidal anti-inflammatory drugs (NSAIDs) in large doses NSAIDs ... to cause immunosuppression. d) Antineoplastic agents Antineoplastic agents are known to cause immunosuppression.

Last Answer : a) Nonsteroidal anti-inflammatory drugs (NSAIDs) in large doses NSAIDs include aspirin and ibuprofen.

The following statement about lithium is not correct: A. It has a sedative action in normal individuals B. It controls mania, but takes 1–2 weeks to produce the effect C. It has prophylactic effect in recurrent unipolar depression D. It can be combined with tricyclic antidepressants for refractory cases of major depression

Description : The following statement about lithium is not correct: A. It has a sedative action in normal individuals B. It controls mania, but takes 1-2 weeks to produce the effect C. ... recurrent unipolar depression D. It can be combined with tricyclic antidepressants for refractory cases of major depression

Last Answer : A. It has a sedative action in normal individuals

Budesonide is a: A. Nonsteroidal antiinflammatory drug B. High ceiling diuretic C. Inhaled corticosteroid for asthma D. Contraceptive

Description : Budesonide is a: A. Nonsteroidal antiinflammatory drug B. High ceiling diuretic C. Inhaled corticosteroid for asthma D. Contraceptive

Last Answer : C. Inhaled corticosteroid for asthma

The following nonsteroidal antiinflammatory drug is a preferential cyclooxygenase-2 (COX-2) inhibitor: A. Tenoxicam B. Meloxicam C. Diclofenac sod. D. Ketoprofen

Description : The following nonsteroidal antiinflammatory drug is a preferential cyclooxygenase-2 (COX-2) inhibitor: A. Tenoxicam B. Meloxicam C. Diclofenac sod. D. Ketoprofen

Last Answer : B. Meloxicam

Choose the correct statement(s) about retroviral protease inhibitors: A. They act at an early step in HIV replication B. They are more active in inhibiting HIV than zidovudine C. They inhibit CYP3A4 and interact with many other drugs D. Both 'B' and 'C' are correct

Description : Choose the correct statement(s) about retroviral protease inhibitors: A. They act at an early step in HIV replication B. They are more active in inhibiting HIV than zidovudine C. They inhibit CYP3A4 and interact with many other drugs D. Both 'B' and 'C' are correct

Last Answer : D. Both 'B' and 'C' are correct

Select the correct statement about tibolone: A. It is an antiestrogen used for palliative treatment of carcinoma breast B. It is an estrogenic + progestational steroid used for hormone replacement therapy in postmenopausal women C. It is an antiandrogen used for male pattern baldness D. It is a nonsteroidal estrogen used topically for senile vaginitis

Description : Select the correct statement about tibolone: A. It is an antiestrogen used for palliative treatment of carcinoma breast B. It is an estrogenic + progestational steroid used for hormone replacement ... for male pattern baldness D. It is a nonsteroidal estrogen used topically for senile vaginitis

Last Answer : B. It is an estrogenic + progestational steroid used for hormone replacement therapy in postmenopausal women

n a 50-year-old male without any other coronary artery disease risk factor, hypocholesterolemic drugs are considered necessary when the serum LDLcholesterol level is higher than: A. 130 mg/dl B. 160 mg/dl C. 190 mg/dl D. 240 mg/d

Description : n a 50-year-old male without any other coronary artery disease risk factor, hypocholesterolemic drugs are considered necessary when the serum LDLcholesterol level is higher than: A. 130 mg/dl B. 160 mg/dl C. 190 mg/dl D. 240 mg/d

Last Answer : C. 190 mg/dl

Low dose therapy with the following category of antihypertensive drugs has been found to be more advantageous in the long-term than high dose therapy with the same drugs: A. β adrenergic blockers B. α1 adrenergic blockers C. Central sympatholytics D. Diuretics

Description : Low dose therapy with the following category of antihypertensive drugs has been found to be more advantageous in the long-term than high dose therapy with the same drugs: A. β adrenergic blockers B. α1 adrenergic blockers C. Central sympatholytics D. Diuretics

Last Answer : D. Diuretics

The following is true of proton pump inhibitors except: A. They are the most effective drugs for Zolinger Ellison syndrome B. Their prolonged use can cause atrophy of gastric mucosa C. They inhibit growth of H. pylori in stomach D. They have no effect on gastric motilit

Description : The following is true of proton pump inhibitors except: A. They are the most effective drugs for Zolinger Ellison syndrome B. Their prolonged use can cause atrophy of gastric mucosa C. They inhibit growth of H. pylori in stomach D. They have no effect on gastric motilit

Last Answer : B. Their prolonged use can cause atrophy of gastric mucosa

Concurrent administration of aspirin interacts unfavourably with the following drugs except: A. Furosemide B. Spironolactone C. Codeine D. Methotrexate

Description : Concurrent administration of aspirin interacts unfavourably with the following drugs except: A. Furosemide B. Spironolactone C. Codeine D. Methotrexate

Last Answer : C. Codeine

Histamine H2 blockers attenuate the gastric secretory response to acetylcholine and pentagastrin as well because: A. H2 blockers block gastric mucosal cholinergic and gastrin receptors as well B. H2 blockers inhibit the proton pump in gastric mucosa C. Acetylcholine and gastrin act partly by releasing histamine in gastric mucosa D. Histamine, acetylcholine and gastrin all act through the phospholipase C-IP3:DAG pathway in gastric mucosa

Description : Histamine H2 blockers attenuate the gastric secretory response to acetylcholine and pentagastrin as well because: A. H2 blockers block gastric mucosal cholinergic and gastrin receptors as well B. H2 ... acetylcholine and gastrin all act through the phospholipase C-IP3:DAG pathway in gastric mucosa

Last Answer : C. Acetylcholine and gastrin act partly by releasing histamine in gastric mucosa

What is true of acid control therapy with H2 blockers: A. It generally heals duodenal ulcers faster than gastric ulcers B. It checks bleeding in case of bleeding peptic ulcer C. It prevents gastroesophageal reflux D. Both ‘A’ and ‘B’ are correct

Description : What is true of acid control therapy with H2 blockers: A. It generally heals duodenal ulcers faster than gastric ulcers B. It checks bleeding in case of bleeding peptic ulcer C. It prevents gastroesophageal reflux D. Both ‘A’ and ‘B’ are correct

Last Answer : A. It generally heals duodenal ulcers faster than gastric ulcers

The following is true of anti-H.pylori therapy except: A. It is indicated in all patients of peptic ulcer B. Resistance to any single antimicrobial drug develops rapidly C. Concurrent suppression of gastric acid enhances efficacy of the regimen D. Colloidal bismuth directly inhibits H.pylori but has poor patient acceptability

Description : The following is true of anti-H.pylori therapy except: A. It is indicated in all patients of peptic ulcer B. Resistance to any single antimicrobial drug develops rapidly C. Concurrent ... efficacy of the regimen D. Colloidal bismuth directly inhibits H.pylori but has poor patient acceptability

Last Answer : A. It is indicated in all patients of peptic ulcer

The nonselective MAO inhibitors are not used clinically as antidepressants because of their: A. Low antidepressant efficacy B. Higher toxicity C. Potential to interact with many foods and drugs D. Both 'B' and 'C' are correct

Description : The nonselective MAO inhibitors are not used clinically as antidepressants because of their: A. Low antidepressant efficacy B. Higher toxicity C. Potential to interact with many foods and drugs D. Both 'B' and 'C' are correct

Last Answer : D. Both 'B' and 'C' are correct

The following drug is added to levodopa therapy of parkinsonism to attenuate ‘wearing off’ effect: A. Selegiline B. Trihexiphenidyl C. Amantadine D. Any of the abov

Description : The following drug is added to levodopa therapy of parkinsonism to attenuate ‘wearing off’ effect: A. Selegiline B. Trihexiphenidyl C. Amantadine D. Any of the abov

Last Answer : A. Selegiline

Choose the correct statement about nateglinide: A. It is a long acting oral hypoglycaemic drug B. Taken just before a meal, it limits postprandial hyperglycaemia in type 2 diabetes mellitus C. It lowers blood glucose in both type 1 and type 2 diabetes mellitus D. It acts by opening K+ channels in myocytes and adipocytes

Description : Choose the correct statement about nateglinide: A. It is a long acting oral hypoglycaemic drug B. Taken just before a meal, it limits postprandial hyperglycaemia in type 2 diabetes mellitus C. It lowers ... 1 and type 2 diabetes mellitus D. It acts by opening K+ channels in myocytes and adipocytes

Last Answer : B. Taken just before a meal, it limits postprandial hyperglycaemia in type 2 diabetes mellitus

Bleeding complications are frequently associated with fibrinolytic therapy. Which of the following statement(s) concerning complications of fibrinolytic therapy is/are true? a. Careful monitoring of prothrombin time and aPTT time are necessary to avoid bleeding complications b. A level of serum fibrinogen less than 100 mg/dl is associated with an increased risk of bleeding c. Recent (less than 10 days) major surgery is a contraindication to systemic but not regional fibrinolytic therapy d. A patient with a cerebrovascular event occurring less than two months ago can be treated with fibrinolytic therapy if head CT scan is normal

Description : Bleeding complications are frequently associated with fibrinolytic therapy. Which of the following statement(s) concerning complications of fibrinolytic therapy is/are true? a. Careful monitoring of prothrombin time ... months ago can be treated with fibrinolytic therapy if head CT scan is normal

Last Answer : Answer: b Fibrinolytic therapy induces a hemostatic defect through a combination of factors. Hypofibrinogenemia and fibrin degradation products inhibit fibrin polymerization and, in combination ... is considered a major relative contraindication to either regional or systemic thrombolytic therapy

Which of the following statements about hypertension in diabetes patients is/are correct? A. Hypertension worsens the macrovascular disease of diabetes patients. B. Hypertension accelerates the progression of diabetic nephropathy. C. Hypertension is associated with sodium retention in diabetes patients. D. Angiotensin-converting enzyme (ACE) inhibitors should be used in all patients with chronic hyperglycemia, regardless of the presence of hypertension. E. Diuretics, as single-drug therapy, are not indicated in the treatment of hypertension in diabetes patients.

Description : Which of the following statements about hypertension in diabetes patients is/are correct? A. Hypertension worsens the macrovascular disease of diabetes patients. B. Hypertension accelerates the ... single-drug therapy, are not indicated in the treatment of hypertension in diabetes patients.

Last Answer : Answer: ABCDE DISCUSSION: All of the answers listed are correct. By damaging endothelial cells, hypertension worsens macrovascular disease in all patients but especially in diabetics. Hypertension ... is not indicated because the chronic state of dehydration in such patients may become worse

The principles of antihypertensive drug usage enunciated in JNC VI and WHO-ISH guidelines include the following except: A. Therapy for grade I and II hypertension should be initiated with a single drug B. Dose of thiazide diuretic should be 12.5-25 mg hydrochlorothiazide or equivalent per day C. All subjects with BP higher than 140/90 mmHg should be put on antihypertensive medication immediately D. If the drug chosen initially fails to lower BP, it should be replaced by a drug/combination from another class

Description : The principles of antihypertensive drug usage enunciated in JNC VI and WHO-ISH guidelines include the following except: A. Therapy for grade I and II hypertension should be initiated with a single drug ... initially fails to lower BP, it should be replaced by a drug/combination from another class

Last Answer : C. All subjects with BP higher than 140/90 mmHg should be put on antihypertensive medication immediately

Propranolol is used in hyperthyroidism: A. As short-term symptomatic therapy till effect of carbimazole develops B. As long-term therapy after subtotal thyroidectomy C. In patients not responding to carbimazole D. To potentiate the effect of radioactive iodine

Description : Propranolol is used in hyperthyroidism: A. As short-term symptomatic therapy till effect of carbimazole develops B. As long-term therapy after subtotal thyroidectomy C. In patients not responding to carbimazole D. To potentiate the effect of radioactive iodine

Last Answer : A. As short-term symptomatic therapy till effect of carbimazole develops

Thrombolytic therapy has become a useful adjunct in the management of peripheral arterial occlusion. In this setting, direct intraarterial administration rather than intravenous has been advocated to decrease the risk of systemic bleeding. Which of the following true statement(s) concerning the use of thrombolytic agents for arterial occlusion is/are true? a. A standard technique involves infusing high-dose urokinase, 4000 units per minute for 1–2 hours, directly into the clot by a catheter embedded in the thrombus b. If progress is made, further fibrinolytic therapy is given at 1000 to 2000 units per minute until clot lysis has occurred c. The usual infusion time by the above-stated technique is usually in excess of 24 hours d. Successful clot lysis occurs more frequently in arterial graf

Description : Thrombolytic therapy has become a useful adjunct in the management of peripheral arterial occlusion. In this setting, direct intraarterial administration rather than intravenous has been advocated ... may be indicated for situations where complete clot evacuation cannot be accomplished surgically

Last Answer : Answer: a, b, e The most popular method for intraarterial thrombolytic therapy for arterial occlusion involves passing a guidewire through the thrombus with arteriographic guidance and ... acute arterial occlusion) or when distal vasculative is occluded and precludes appropriate inflow patency

Disease modifying antirheumatic drugs are indicated in rheumatoid arthritis: A. In place of NSAIDs in patients who donot tolerate the latter B. Along with NSAIDs in patients with progressive disease C. Only when NSAIDs fail to afford symptomatic relief D. In all patients irrespective of disease status/ concurrent medication

Description : Disease modifying antirheumatic drugs are indicated in rheumatoid arthritis: A. In place of NSAIDs in patients who donot tolerate the latter B. Along with NSAIDs in patients with progressive ... to afford symptomatic relief D. In all patients irrespective of disease status/ concurrent medication

Last Answer : B. Along with NSAIDs in patients with progressive disease

Addition of a progestin for 10-12 days every month to cyclic estrogen replacement therapy during menopause is recommended because the progestin: A. Prevents osteoporosis B. Prevents irregular bleeding C. Blocks increased risk of endometrial carcinoma D. Both ‘B’ and ‘C’ are correct

Description : Addition of a progestin for 10-12 days every month to cyclic estrogen replacement therapy during menopause is recommended because the progestin: A. Prevents osteoporosis B. Prevents irregular bleeding C. Blocks increased risk of endometrial carcinoma D. Both ‘B’ and ‘C’ are correct

Last Answer : D. Both ‘B’ and ‘C’ are correct

Clinically, the angiotensin antagonists share the following features of angiotensin converting enzyme inhibitors except: A. Antihypertensive efficacy B. Potential to reverse left ventricular hypertrophy C. Lack of effect on carbohydrate tolerance D. Potential to induce cough in susceptible individuals

Description : Clinically, the angiotensin antagonists share the following features of angiotensin converting enzyme inhibitors except: A. Antihypertensive efficacy B. Potential to reverse left ventricular hypertrophy ... of effect on carbohydrate tolerance D. Potential to induce cough in susceptible individuals

Last Answer : D. Potential to induce cough in susceptible individuals