answer:Dosage for Aleve is one every twelve hours, with food. Two at a time is an overdose and can cause harm to stomach and GI tract. Lots of damage can take place before vomiting occurs. Vicodin is a narcotic and a different kettle of fish entirely. One always starts with the weakest analgesic or pain killer possible. And then ratchets up on advice of Doc. Google “Aleve vs. Vicodin” for more detailed info.