Description : Two cyclic polypeptide antibiotics are a. Vancomycin and streptomycin. b. Penicillin and cephalosporin. c. Bacitracin and polymyxins d. .gentamicin and chloramphenicol
Last Answer : c. Bacitracin and polymyxins
Description : Methicillin resistant staphylococci do not respond to ß-lactam antibiotics because (a) They produce a ß-lactamase which destroys methicillin and related drugs (b) They elaborate an amidase which destroys ... low affinity for ß-lactam antibiotics (d) They are less permeable to ß-lactam antibiotics
Last Answer : Ans: C
Description : Two drugs that affect cell wall synthesis are a. Erythromycin and penicillin. b. Vancomycin and cephalosporin. c. Tetracycline and polymyxin b. d. Chloramphenicol and streptomycin.
Last Answer : a. Erythromycin and penicillin.
Description : Which one of the following pairs is incorrectly matched as to antibiotic and use? a. Penicillin-gram-positive bacteria b. Nystatin-fungi c. Tetracycline-viruses d. Griseofulvin-fungi
Last Answer : c. Tetracycline-viruses
Description : Methicillin resistant staphylococci do not respond to β-lactam antibiotics because: A. They produce a β-lactamase which destroys methicillin and related drugs B. They elaborate an amidase which destroys ... low affinity for β-lactam antibiotics D. They are less permeable to β-lactam antibiotics
Last Answer : C. They have acquired penicillin binding protein which has low affinity for β-lactam antibioti
Description : The last step in synthesis of peptidoglycan is A- attachment of a peptide to muramic acid B- attaching two amino acids to form a cross-link C- attachment of a portion of peptidoglycan to a membrane lipid D- binding of penicillin to a membrane protein
Last Answer : attaching two amino acids to form a cross-link
Description : How would you treat Denture Stomatitis A. Tetracycline B. Systemic penicillin C. Nystatin
Last Answer : C. Nystatin
Description : A woman’s neglected hangnail has developed into a mild staphylococcal cellulites. Which of the following regimens would be appropriate oral therapy? (a) Dicloxacillin 125 mg q6h (b) Vancomycin 250 mg q6h (c) Methicillin 500 mg q6h (d) Cefazolin 1 g q8h (e) Penicillin V 500 mg q6h
Last Answer : Ans: A
Description : Which of the following penicillins are readily destructed by stomach acid: A. Methicillin B. Cloxacillin C. Phenoxy methyl D. Penicillin G
Last Answer : D. Penicillin G
Description : Bacitracin, Polymyxin and Neomycin are used together for topical skin infections under the name of _____. a. Neosporin b. Vancomycin c. Cephalosporin d. Nystatin.
Last Answer : a. Neosporin
Description : A Candida albicans infection of the intestine, vagina, or oral cavity are commonly treated with a. cefotaxime. b. vidarabine. c. streptomycin. d. nystatin.
Last Answer : d. nystatin.
Description : _____ cause a yellow-gray-brown discoloration of teeth and stunted bones in children, which have limited its use to adults. a. Methicillin b. Vancomycin c. Tetracycline d. Erythromycin
Last Answer : c. Tetracycline
Description : A medium would involve the addition of the antibiotic methicillin to identify methicillin-resistant bacteria. a. differential b. selective c. thioglycollate d. VBNC
Last Answer : b. selective
Description : Antibiotics inhibiting nucleic acid synthesis include a. Rifampin and quinolones. b. Aminoglycosides and tetracyclines. c. Lincosamides and streptogramins. d. Macrolides and ami noglycosides.
Last Answer : a. Rifampin and quinolones.
Description : A 55-year-old renal transplant patient has been hospitalized in a Surgical Intensive Care Unit, receiving a prolonged course of antibiotics following an attack of acute cholecystitis. The ... suggest a dosage reduction in immunosuppressive agents until the infection can be adequately controlled
Last Answer : Answer: a, d Infections due to fungal pathogens have become increasingly common during the past decade, frequently occurring in patients undergoing prolonged hospitalization in the Surgical ... agents should be discontinued until evidence of infection is absolutely controlled or is eradicated
Description : Clotrimazole and nystatin are both A. topical antifungals B. anti-itch creams C. topical antibiotics D. used to treat eczema
Description : Which of the following may be most likely to be missing from a gram-positive bacterium? A.Penicillin binding protein B.Peptidoglycan C.Lipopolysaccharide D.Phospholipid bilayer membrane
Last Answer : C.Lipopolysaccharide
Description : Mitochondrial protein synthesis is inhibited by (A) Cycloheximide (B) Chloramphenicol (C) Diptheria toxin (D) None of these
Last Answer : Answer : B
Description : The most important mechanism by which gram negative bacilli acquire chloramphenicol resistance is (a) Decreased permeability into the bacterial cell (b) Acquisition of a plasmid encoded ... bacterial ribosome for chloramphenicol (d) Switching over from ribosomal to mitochondrial protein synthesis
Last Answer : Ans: B
Description : Select the antibiotic which inhibits bacterial protein synthesis by interfering with translocation of elongating peptide chain from acceptor site back to the peptidyl site of the ribosome so that ... chain is prematurely terminated: A. Chloramphenicol B. Erythromycin C. Tetracycline D. Streptomycin
Last Answer : B. Erythromycin
Description : Chloramphenicol inhibits bacterial protein synthesis by: A. Binding to 30S ribosome and inhibiting attachment of aminoacyl tRNA B. Binding to 50S ribosome and preventing peptide bond formation C. Binding to ... chain D. Binding to both 30S and 50S ribosome and inducing misreading of mRNA code
Last Answer : B. Binding to 50S ribosome and preventing peptide bond formation
Description : Which one of the following is considered as the drug of last resort for human beings? (1) Penicillin (2) Tetracycline (3) Chloramphenicol (4) Streptomycin
Last Answer : (3) Chloramphenicol Explanation: Chloramphenicol is an antibiotic useful for the treatment of a number of bacterial infections. This includes use as an eye ointment to treat conjunctivitis.
Description : The following antibiotic accentuates the nuromuscular blockade produced by pancuronium: A. Streptomycin B. Erythromycin C. Penicillin G D. Chloramphenicol
Last Answer : A. Streptomycin
Description : Gary baby syndrome occur in new born with a) Tetracycline b) Chloramphenicol c) Penicillin d) Erythromycin
Last Answer : b) Chloramphenicol
Description : Which out of the following antibiotics penetrates blood-CSF barrier the best (a) Erythromycin (b) Gentamicin (c) Tetracycline (d) Chloramphenicol
Last Answer : Ans: D
Description : Drug destroying type of bacterial resistance is important for the following antibiotics except: A. Cephalosporins B. Tetracyclines C. Chloramphenicol D. Aminoglycosides
Last Answer : B. Tetracyclines
Description : The following is true of vancomycin except: A. It is a bactericidal antibiotic active primarily against gram positive bacteria B. It acts by inhibiting bacterial protein synthesis C. It is an alternative to penicillin for enterococcal endocarditis D. It can cause deafness as a dose related toxicity
Last Answer : B. It acts by inhibiting bacterial protein synthesis
Description : Which one of the following is NOT an inhibitor of protein synthesis? a. Clindamycin b. Macrolides c. Rifampin d. Chioramphenicol
Last Answer : c. Rifampin
Description : Vancomycin inhibits _____________ synthesis. a. protein b. DNA c. bacterial cell wall d. RNA
Last Answer : c. bacterial cell wall
Description : Trimethoprim and sulfamethoxazole are examples of synthesis. a. Sulfonamides; PABA b. Penicillins; Cell Wall c. Sulfonamides; Folic Acid d. Macrolides; Protein
Last Answer : c. Sulfonamides; Folic Acid
Description : A characteristic of protein synthesis in both the archaea and eukarya is A.transcription and translation are coupled B.translation is inhibited by diphtheria toxin C.proteins are synthesized from D-, ... L-, isomers of amino acids D.the initiator tRNA is charged with N-formyl- methionine
Last Answer : C.proteins are synthesized from
Description : The mode of action of polymyxin is to A- inhibit protein synthesis B- inhibit DNA synthesis C- injury to the plasma membrane D- inhibit folic acid synthesis
Last Answer : injury to the plasma membrane
Description : Negative regulation of protein synthesis is accomplished by A- allosteric inhibition B- the binding of RNA polymerase to the promoter C- the binding of a repressor to the DNA D- the binding of a repressor to the RNA polymerase
Last Answer : the binding of a repressor to the DNA
Description : Which of the following act as the blueprint or template for the process of protein synthesis that takes place on ribosomes? A.rRNA B.DNA C.tRNA D.mRNA
Last Answer : mRNA
Description : The final step of gene expression is protein synthesis, which is also known as A- replication B- translation C- transcription D- none of these
Last Answer : translation
Description : A characteristic of protein synthesis in both the archaea and eukarya is A- transcription and translation are coupled B- translation is inhibited by diphtheria toxin C- .proteins are synthesized from D-, rather than L-, isomers of amino acids D- the initiator tRNA is charged with N-formyl-methionine
Last Answer : .proteins are synthesized from D-, rather than L-, isomers of amino acids
Description : Where does protein synthesis take place in all cells? a. mitochondria b. cell membranes c. ribosomes d. Golgi apparatus
Last Answer : c. ribosomes
Description : Which one of the following is NOT an organizational pattern common to all organisms? a. Genetic organization b. Protein synthesis c. Compartmentation d. Microcompartments
Last Answer : d. Microcompartments
Description : The most important mechanism by which tetracycline antibiotics exert antiimicrobial action is (a) They chelate Ca2+ ions and alter permeability of bacterial cell membrane (b) They bind to 30S ribosomes ... peptide chain in the bacteria (d) They interfere with DNA mediated RNA synthesis in bacteria
Description : What is true of Quinupristin-Dalfopristin: A. It is a synergistic combination of two similar antibiotics B. It acts by inhibiting bacterial protein synthesis C. It is active against most resistant coccal infections D. All of the above are correct
Last Answer : D. All of the above are correct
Description : Bactericidal action of aminoglycoside antibiotics is due to: A. Inhibition of bacterial protein synthesis B. Alteration of bacterial cell membrane permeability C. Damage to bacterial cell wall D. Inhibition of bacterial oxidative metabolism
Last Answer : B. Alteration of bacterial cell membrane permeability
Description : Select the class of antibiotics which act by interfering with bacterial protein synthesis, but are bactericidal: A. Tetracyclines B. Aminoglycosides C. Macrolides D. Lincosamides
Last Answer : B. Aminoglycosides
Description : The most important mechanism by which tetracycline antibiotics exert antimicrobial action is: A. They chelate Ca2+ ions and alter permeability of bacterial cell membrane B. They bind to 30S ribosomes ... peptide chain in the bacteria D. They interfere with DNA mediated RNA synthesis in bacteria
Last Answer : B. They bind to 30S ribosomes and inhibit bacterial protein synthesis
Description : Antibiotics will not work against _____ diseases because they lack the structures and metabolic machinery with which antibiotics interfere. a. viral b. bacterial c. fungal d. protozoan
Last Answer : a. viral
Description : Two major drawbacks to the use of ______ is allergies and beta- lactamases produced by resistant bacteria. a. Tetracycline b. Penicillin c. Cephalosporin d. Bacitracin
Last Answer : b. Penicillin
Description : ____ is examples of drugs that are derived from the metabolism of microorganisms. a. Salvarsan b. Prontosil c. Penicillin d. A-C are correct
Last Answer : c. Penicillin
Description : The re-isolation and purification of penicillin was carried out by a. Waksman. b. Florey and Chain. c. Domagk. d. Fleming.
Last Answer : b. Florey and Chain.
Description : Ehrlich and Hata discovered that was used to treat a. Salvarsan; syphilis b. penicillin; surgical wounds c. Salvarsan; malaria. d. Prontosil; malaria
Last Answer : a. Salvarsan; syphilis
Description : Medications that can be used early in influenza are ____ and ____ because they inhibit the release of new virions. a. aspirin, decongestants b. Relenza, Tamiflu c. Penicillin, ampicillin d. AZT, ribivirin
Last Answer : b. Relenza, Tamiflu
Description : Though few in number, some drugs, such as _____, can be used to treat some viral infections. a. penicillin and ampicillin b. isoniazid and dapsone c. amantadine and acyclovir d. streptomycin and amphotericin
Last Answer : c. amantadine and acyclovir