Description : Two drugs that affect cell wall synthesis are a. Erythromycin and penicillin. b. Vancomycin and cephalosporin. c. Tetracycline and polymyxin b. d. Chloramphenicol and streptomycin.
Last Answer : a. Erythromycin and penicillin.
Description : According to Rawlins–Thompson classification Type D ADR includes___________ a) Carcinogenesis b) Bradycardia associated with beta blockers c) Anaphylaxis associated with penicillin d) Opiate withdrawal syndrome
Last Answer : a) Carcinogenesis
Description : Which out of the following antibiotics penetrates blood-CSF barrier the best (a) Erythromycin (b) Gentamicin (c) Tetracycline (d) Chloramphenicol
Last Answer : Ans: D
Description : An 8-year-old child presented with brownish discoloured and deformed anterior teeth. History of having received an antibiotic about 4 years earlier was obtained. Which antibiotic could be responsible for the condition ? (a) Chloramphenicol (b) Tetracycline (c) Erythromycin (d) Genetamicin
Last Answer : Ans: B
Description : Select the antibiotic which inhibits bacterial protein synthesis by interfering with translocation of elongating peptide chain from acceptor site back to the peptidyl site of the ribosome so that ... chain is prematurely terminated: A. Chloramphenicol B. Erythromycin C. Tetracycline D. Streptomycin
Last Answer : B. Erythromycin
Description : The following antibiotic penetrates blood-CSF barrier the best: A. Erythromycin B. Gentamicin C. Tetracycline D. Chloramphenicol
Last Answer : D. Chloramphenicol
Description : An 8-year-old child presented with brownish discoloured and deformed anterior teeth. History of having received an antibiotic about 4 years earlier was obtained. Which antibiotic could be responsible for the condition: A. Chloramphenicol B. Tetracycline C. Erythromycin D. Gentamicin
Last Answer : Tetracycline
Description : 2 Which antibiotic is primarily bacteriostatic but becomes bactericidal at higher concentrations: A. Erythromycin B. Tetracycline C. Chloramphenicol D. Ampicillin
Last Answer : A. Erythromycin Although erythromycin is primarily bacteriostatic, it is bactericidal at high concentrations for some Gram-positive species, such as group A streptococci and pneumococci
Description : All are Selected Cytochrome P3A4 Inducer EXCEPT___________ a) Efavirenz b) Erythromycin c) Dexamethasone d) Nevirapine
Last Answer : b) Erythromycin
Description : When tetracycline is given with antacids the absorption of tetracycline ----------------. a) Increases b) Decreases c) Minimally altered d) Not altered at all
Last Answer : b) Decreases
Description : The following antibiotic accentuates the nuromuscular blockade produced by pancuronium: A. Streptomycin B. Erythromycin C. Penicillin G D. Chloramphenicol
Last Answer : A. Streptomycin
Description : Which one of the following is considered as the drug of last resort for human beings? (1) Penicillin (2) Tetracycline (3) Chloramphenicol (4) Streptomycin
Last Answer : (3) Chloramphenicol Explanation: Chloramphenicol is an antibiotic useful for the treatment of a number of bacterial infections. This includes use as an eye ointment to treat conjunctivitis.
Description : In which of the following groups do all four drugs warrant careful monitoring for drugrelated seizures in high-risk patients? (a) Penicillin G, imipenem, amphotericin B, metronidazol ... (d) Cycloserine, metronidazole, vancomycin, sulfadiazine (e) Metronidazole, imipenem, doxycycline, erythromycin
Last Answer : Ans: A
Description : Which of the following would you classify as a pharmacodynamics interaction? a) ACE inhibitors with potassium-sparing diuretics cause life-threatening hyperkalaemia b) Antacids reduce the absorption ... Increased bleeding due to cimetidine and warfarin d) Probenecid increases half-life of penicillin
Last Answer : a) ACE inhibitors with potassium-sparing diuretics cause life-threatening hyperkalaemia
Description : Which of the following drug is not needed to be TDM? a) Carbamazepine. b) Penicillin. c) Digoxin. d) Gentamicin.
Last Answer : b) Penicillin.
Description : Which of the following is a valid therapeutic use of interaction? A. Use of Probenecid with Penicillin B. Giving Aspirin with warfarin C. Instructing patient to take levofloxacin with milk or antacid D. Treatment of depression of MAO Inhibitor and Citalopram
Last Answer : A. Use of Probenecid with Penicillin
Description : A child presented with polyuria, weakness and fever. On the basis of investigations he was labelled to be suffering from Fancony syndrome. A history of taking some old left over antibiotic ... What could have been the antibiotic: A. Tetracycline B. Chloramphenicol C. Ampicillin D. Cephalexi
Last Answer : A. Tetracycline
Description : Peptidyl transferase activity of 50 S ribosomal subunits is inhibited by (A) Rifampicin (B) Cycloheximide (C) Chloramphenicol (D) Erythromycin
Last Answer : Answer : C
Description : Binding of formylmehtionyl tRNA to 30 S ribosomal subunit of prokaryotes is inhibited by (A) Streptomycin (B) Chloramphenicol (C) Erythromycin (D) Mitomycin
Last Answer : Answer : A
Description : Select the antibiotic whose dose must be reduced in patients with renal insufficiency (a) Ampicillin (b) Chloramphenicol (c) Tobramycin (d) Erythromycin
Last Answer : Ans: C
Description : A premature neonate suffered respiratory distress and was given an antibiotic 100 mg/kg/day orally. Over the next two days his condition worsened, he become dull, stopped feeding, developed ... most likely antibiotic given to him: A. Ampicillin B. Chloramphenicol C. Erythromycin D. Ciprofloxacin
Last Answer : B. Chloramphenico
Description : Select the antibiotic whose dose must be reduced in patients with renal insufficiency: A. Ampicillin B. Chloramphenicol C. Tobramycin D. Erythromycin
Last Answer : C. Tobramycin
Description : Which one of the following antibiotics is a potent inducer of hepatic drug-metabolizing enzymes? (a) Ciprofloxacin (b) Cyclosporine (c) Erythromycin (d) Rifampin (e) Tetracycline
Description : In the empiric treatment of severe bacterial infections of unidentified entiology, this drug, often used in combination with an aminoglycoside, provides coverage against many staphylococci (a) Amoxicillin (b) Clavulanic acid (c) Erythromycin (d) Nafcillin (e) Tetracycline
Description : Which antibiotic inhibits interaction between tRNA and mRNA during bacterial protein synthesis? (a) Tetracycline (b) Erythromycin (c) Neomycin (d) Streptomycin
Last Answer : (d) Streptomycin
Description : .Which antibiotic inhibits interaction between tRNA and mRNA during bacterial protein synthesis? (a) Tetracycline (b) Erythromycin (c) Neomycin (d) Streptomycin
Last Answer : (c) Neomycin
Description : _____ cause a yellow-gray-brown discoloration of teeth and stunted bones in children, which have limited its use to adults. a. Methicillin b. Vancomycin c. Tetracycline d. Erythromycin
Last Answer : c. Tetracycline
Description : Which of the following statements best describes a lead compound? a) A compound that contains the element lead b) A compound from the research laboratory that is chosen to go forward for preclinical and ... of a drug. d) The first compound of a structural class of compounds to reach the market.
Last Answer : c) A molecule that shows some activity or property of interest and serves as the starting point for the development of a drug.
Description : Which of the following patients are at the highest risk of suffering from an adverse drug reaction? a) An 8 month year old infant receiving a prescription for an antibiotic. b) A 22 year old patient ... ACE Inhibitor. d) A 68 year old patient who has oedema receiving a prescription for a diuretic.
Last Answer : d) A 68 year old patient who has oedema receiving a prescription for a diuretic.
Description : You are asked to compare the cost of four different antibacterial medicines. Which of the following treatment courses is the lowest cost? a) Medicine A costs £17.00 for 28 tablets. The adult dose is one ... 14 tablets. The adult dose is one tablet each day and the usual treatment duration is 5 days.
Last Answer : c) Medicine C costs £20.00 for 25 tablets. The adult dose is one tablet twice a day and the usual treatment duration is 5 days.
Description : Which of the following adverse drug reactions would you report to the Medicines and Healthcare Products regulatory Agency (MHRA) via the yellow card system for reporting? a) A patient ... started taking ramipril. d) A patient complains they have experienced diarrhoea since taking azilsartan.
Last Answer : d) A patient complains they have experienced diarrhoea since taking azilsartan.
Description : GCP are seen in all of the following except a) Phase I trial b) Phase II trial c) Preclinical trials d) Phase IV trial
Last Answer : c) Preclinical trials
Description : Pharmacovigilance is done for monitoring of a) Drug price b) Unethical practises c) Drug safety d) Pharmacy students
Last Answer : c) Drug safety
Description : Which of the following is Type B ADRS? a) Hypoglycaemia caused by Insulin b) Dryness of mouth caused by Atropine c) Anaemia in patient with G6PD deficiency caused by Primaquine d) Hyperglycaemia caused by thiazide diuretics
Last Answer : c) Anaemia in patient with G6PD deficiency caused by Primaquine
Description : Absorption of Griseofulvin increases with --------------diet. a) Carbohydrate b) Fatty c) protein d) vitamin
Last Answer : b) Fatty
Description : Patient counselling helps to a) Know chemical structure of drug b) Develop business relations with pharmacist c) Motivate the patient to take medicine for improvement of his/her health status. d) Pass time at old age
Last Answer : c) Motivate the patient to take medicine for improvement of his/her health status.
Description : Idiosyncrasy is_______________. a) Type A ADRs b) Type B ADRs c) Type C ADRs d) Type D ADRs
Last Answer : b) Type B ADRs
Description : A 75-year-old man had been receiving gentamicin (an aminoglycoside antibiotic) to treat an urinary tract infection. After three months of therapy patient's serum creatinine levels were 10 mg/ ... Type II allergic reaction b)Type III allergic reaction c) Pseudo allergic reaction d) Overdose toxicity
Last Answer : d) Overdose toxicity
Description : Which of the following terms does not describe an Adverse Drug Reaction? a) Idiosyncrasy b) Anaphylaxis c) Teratogenic effect d) Placebo effect
Last Answer : d) Placebo effect
Description : Which of the following is a technique pharmacists can use to humanize themselves to their patients? a) Using the patient's preferred name in conversation b) Delegating as many tasks as possible to an ... the text of a medication bottle verbatim to a patient d) Providing business cards at the desk
Last Answer : c) Reading the text of a medication bottle verbatim to a patient
Description : GCP provides public assurance that a) Rights and safety of participants are protected b) The rights, safety and wellbeing of research participants are protected and that research data are reliable. c) Results are reliable d) Safety of participant is observed and results are reliable
Last Answer : b) The rights, safety and wellbeing of research participants are protected and that research data are reliable.
Description : Which is person responsible for the conduct of the clinical trial at a trial site? a) Clinical Research Coordinator b) Monitor c) Investigator d) Sponsor
Last Answer : c) Investigator
Description : What are Good Clinical Practices? a. Regulations set in place by Government that how clinical trials are supposed to be managed. b. Clinical practices that adhere to the best standards of ... practice during clinical trials d. The FDA's requirements for how trials are conducted and documented
Last Answer : d. The FDA’s requirements for how trials are conducted and documented
Description : Cimetidine interacts with more drugs than ranitidine because; a) It is subjected to greater first pass metabolism b) It is a more potent enzyme inducer c) It is a more potent enzyme inhibitor d) It has better oral absorption
Last Answer : c) It is a more potent enzyme inhibitor
Description : The purpose of preclinical testing is: a. To verify that a drug is sufficiently safe and effective to be tested in humans. b. To undergo preliminary testing in healthy humans to monitor the ... for the larger scale future tests on a widespread population. d. To develop method of drug analysis
Last Answer : a. To verify that a drug is sufficiently safe and effective to be tested in humans.
Description : ______________ of clinical trial involves first time human trial in a small number of patients. a Phase I b Phase II c Phase III d Phase IV
Last Answer : a Phase I
Description : A 92-year-old woman is an inpatient in the geriatric unit. She has multivascular dementia. She is more confused and agitated. She has been given lorazepam 4 mg intramuscularly. She is now unconscious ... A. Activated charcoal B. Flumazenil C. N-acetyl cysteine D. Naloxone E. Protamine sulphate
Last Answer : B. Flumazenil
Description : Case control studies is called as A. Drug-oriented systems. B. Dose-oriented systems. C. Disease-oriented systems. D. Complication-oriented systems.
Last Answer : B. Dose-oriented systems.
Description : Which of the following medication is safe to use in the third trimester of pregnancy? A. Acetaminophen B. Warfarin C. Aspirin D. Oxycodone
Last Answer : A. Acetaminophen
Description : Which of the following antihypertensive agents should be avoided in the elderly patients? A. Amlodipine B. Atenolol C. Benazepril D. Methyldopa
Last Answer : D. Methyldopa