Description : A 55 year-old female complaining of vague tiredness is found to have a serum corrected calcium concentration of 2.9 mmol/l. Examination was unremarkable. Which of the following results ... 4) Low normal plasma phosphate concentration 5) Low normal serum 25-hydroxyvitamin D concentration
Last Answer : Answers-3 Bit too easy really. A high or even normal PTH concentration in the presence of hypercalcaemia would support the diagnosis of hyperparathyroidism. A high urinary Calcium concentration may ... but neither confirm the diagnosis. Elevated 1,25 VitD suggests a diagnosis of hypervitaminosis D.
Description : The following is not a feature of hyper-vitaminosis D: A. Hypertension B. Spontaneous fractures C. Renal stones D. Weakness
Last Answer : B. Spontaneous fractures
Description : Parathyroid hormone (A) Is released when serum Ca++ is too high (B) Inactivates vitamin D (C) Is secreted when Ca++ is too low (D) Depends on vitamin K for adequate activity
Last Answer : Answer : C
Description : The most useful test for the diagnosis of acute hemorrhagic pancreatitis during the first few days is (A) Urinary lipase test (B) Serum calcium (C) Urinary amylase (D) Serum amylase
Last Answer : Answer : D
Description : Levels of serum calcium and inorganic phosphorus are increased in (A) Hypervitaminosis D (B) Hypoparathyroidism (C) Hypovitaminosis D (D) None of these
Last Answer : Answer : A
Description : An 80 year old male presented with dull aching loin pain & interrupted voiding of urine. BUN and creatinine were increased. US revealed a bilateral hydronephrosis. What is the most probable Dx? a) Stricture of the urethra b) Urinary bladder tumor c) BPH d) Pelvic CA e) Renal stone
Last Answer : c) BPH
Description : A 75-year-old man had been receiving gentamicin (an aminoglycoside antibiotic) to treat an urinary tract infection. After three months of therapy patient's serum creatinine levels were 10 mg/ ... Type II allergic reaction b)Type III allergic reaction c) Pseudo allergic reaction d) Overdose toxicity
Last Answer : d) Overdose toxicity
Description : All the following statements about obstructive jaundice are true except (A) Prothrombin time may be prolonged due to impaired absorption of vitamin K (B) Serum alkaline phosphatase may be raised ... systemic circulation due to biliary obstruction (D) There is no defect in conjugation of bilirubin
Last Answer : Answer : B
Description : The characteristic of hyperparathyroidism is (A) Low serum calcium (B) High serum phosphorous (C) Low serum calcium and high serum phosphorous (D) High serum calcium and low serum phosphate
Description : Which of the following is true concerning a 68 year old male with type 2 diabetes diagnosed with type IV renal tubal acidosis? 1) Aminoaciduria would be expected. 2) Fludrocortisone treatment is effective ... 4) Increased urinary bicarbonate would be expected. 5) Normal renal handling of K+ and H+
Last Answer : Answers-2 H+ secretion, sodium reabsorption and ammonia production diminishes. RTA 4 is in effect hyporeninaemic hypoaldosteronism or failure of aldosterone action and thus helped treated with ... particularly. Aminoaciduria and increased urine bicarbonate are features of RTA types 1 and 2.
Description : The best test for acute pancreatitis in the presence of mumps is (A) A serological test for mumps (B) Serum amylase (C) Urinary amylase (D) Serum lipase
Description : In acute pancreatitis, the enzyme raised in first five days is (A) Serum amylase (B) Serum lactic dehydrogenase (C) Urinary lipase (D) Urinary amylase
Description : A 53-year-old man presented with hypertension of 150/110 mmHg. He is generally asymptomatic and has no previous medical history of note. He is a smoker of 5 cigarettes daily and drinks ... Adrenocortical adenoma 2) Bartter's syndrome 3) Liddle's syndrome 4) Liquorice ingestion 5) Pheochromocytoma
Last Answer : Answers-1 This patient is most likely to have Conn's syndrome as reflected by the hypokalaemic hypertension. Liquorice ingestion or Liddle's syndrome are again possible causes of ... hypertension (often diastolic hypertension), muscular weakness, paresthesias, headache, polyuria, and polydipsia."
Description : Normal total serum calcium level varies between (A) 4–5 mg (B) 9–11 mg (C) 15–20 mg (D) 50–100 mg WATER AND ELECTROLYTE BALANCE 281
Description : Salicylate poisoning can cause (A) Respiratory acidosis (B) Metabolic acidosis with normal anion gap (C) Metabolic acidosis with increased anion gap (D) Metabolic alkalosis
Description : Which of the following statements regarding hypercalcemia are true? A. The symptoms of hypercalcemia may mimic some symptoms of hyperglycemia. B. Metastatic breast cancer is an unusual cause of ... fluid volume deficit. E. Urinary calcium excretion may be increased by vigorous volume repletion.
Last Answer : Answer: ADE DISCUSSION: Markedly elevated serum calcium levels produce polydipsia, polyuria, and thirst. Vigorous volume repletion and saline diuresis correct the extracellular fluid volume ... , from bony metastasis. The calcitonin effect on calcium is diminished with repeat administrations
Description : Which one of the following is true of IgE? 1) Is present in plasma in the same concentration as IgG 2) Is increased acutely in an asthmatic attack 3) Crosses the normal placenta 4) Is increased in the serum of atopic individuals 5) Is involved in type 2 hypersensitivity
Last Answer : Answers-4 IgG is the predominant form of immunoglobulin in plasma at a concentration around 10,000 times that of IgE. IgG crosses the placenta to confer immunity to the fetus but IgE does ... frequently increased in those with atopy but serum IgE does not rise acutely during an asthmatic attack.
Description : The normal serum concentration of vitamin A in mg/100 ml is (A) 5–10 (B) 15–60 (C) 100–150 (D) 0–5
Description : Which of the following is true? Hypochromic anaemia is not due to iron deficiency except (A) Serum ‘Fe’ is high (B) Normal/low transferrin (C) Stainable iron in bone marrow (D) Iron therapy is affective
Description : An inherited or acquired renal tubular defect in the reabsorption of phosphate (Vit D resistant ricket) is characterized with (A) Normal serum Phosphate (B) High serum phosphate (C ... blood phosphorous with elevated alkaline Phosphate (D) A high blood phosphorous with decreased alkaline phosphatase
Description : Characteristics of Vitamin D and its metabolites include which one of the following? (a) Act to decrease serum levels of calcium (b) Activation of their Vitamin D receptors increases cellular CAMP ... Vitamin D increase renal excretion of calcium (e) Vitamin D deficiency results in Pager's disease
Last Answer : Ans: C
Description : A classic sign of cardiogenic shock is a) Tissue hypoperfusion Tissue hypoperfusion is manifested as cerebral hypoxia (restlessness, confusion, agitation). b) High blood pressure Low blood pressure is ... . d) Increased urinary output Decreased urinary output is a classic sign of cardiogenic shock.
Last Answer : a) Tissue hypoperfusion Tissue hypoperfusion is manifested as cerebral hypoxia (restlessness, confusion, agitation).
Description : Calcium absorption is increased by (A) Vitamin D (B) Vitamin C (C) Vitamin K (D) Vitamin E
Description : In ricket, the product of Ca x p (in mg/ 100 ml) in serum is below (A) 30 (B) 50 (C) 70 (D) 100
Description : In serum product of Ca x p (in mg/100ml) in children is normally (A) 20 (B) 30 (C) 50 (D) 60
Description : Calcitonin causes (A) Calcinuria and phosphaturia (B) Decrease in urinary calcium (C) Decrease in urinary phosphorous (D) Increase in blood calcium level 212 MCQs IN BIOCHEMISTRY
Description : Absorption of calcium is increased on a (A) High protein diet (B) Low protein diet (C) High fat diet (D) Low fat diet
Description : Increased serum levels of which of the following may be associated with a decreased risk of atherosclerosis? (a) Very low-density lipoproteins (VLDL) (b) Low-density lipoproteins (LDL) (c) Intermediate – density lipoproteins (IDL) (d) High-density lipoproteins (HDL) (e) Cholesterol
Last Answer : Ans: D
Description : The normal serum value for potassium is a) 3.5-5.5 mEq/L. Serum potassium must be within normal limits to prevent cardiac dysrhythmias. b) 135-145 mEq/L. Normal serum sodium is 135-145 mEq/L. c) 96-106 mEq/L. ... is 96-106 mEq/L. d) 8.5-10.5 mg/dL. Normal total serum calcium is 8.5-10.5mg/dL.
Last Answer : a) 3.5-5.5 mEq/L. Serum potassium must be within normal limits to prevent cardiac dysrhythmias.
Description : Urinary water loss is increased in (A) Diabetes mellitus (B) Diabetes insipidus (C) Chronic glomerulonephritis (D) All of these
Description : Increased urinary excretion of orotic acid can occur in deficiency of (A) Orotate phosphoribosyl transferase (B) OMP decarboxylase (C) Mitochondrial ornithine transcarbamoylase (D) Any of the above
Description : Urinary excretion of vanillyl madelic acid is increased in (A) Phaeochromocytoma (B) Cushing’s syndrome (C) Carcinoid syndrome (D) Aldosteronism
Description : The characteristic urinary finding in porphyria cutanea tarda is (A) Increased quantity of porphobilinogen (B) Increased quantity of red cell protoporphyrin (C) Increased quantity of uroporphyrin (D) Increased quantity of δ-ALA
Description : The characteristic urinary finding in acute intermittent porphyria is (A) Increased quantity of uroporphyrin (B) Increased quantity of coproporphyrin I (C) Increased quantity of coproporphyrin III (D) Massive quantities of porphobilinogen
Description : Pentosuria is a rare hereditary disease is characterized by increased urinary excretion of (A) L-xylulose (B) Xylitol (C) Xylulose 5-phosphate (D) Ribose 5-phosphate
Description : Folic acid deficiency can be diagnosed by increased urinary excretion of (A) Methylmalonate (B) Figlu (C) Cystathionine (D) Creatinine
Description : In obstructive jaundice, urinary bilirubin is (A) Absent (B) Increased (C) Present (D) Present in small amount
Description : Increased urinary indole acetic acid is diagnostic of (A) Maple syrup urine disease (B) Hartnup disease (C) Homocystinuia (D) Phenylketonuria
Description : All the following are true about phenylketonuria except (A) Deficiency of phenylalanine hydroxylase (B) Mental retardation (C) Increased urinary excretion of p-hydroxyphenyl pyruvic acid (D) Decrease serotonin formation
Description : All the following statements about phenylketonuria are correct except (A) Phenylalanine cannot be converted into tyrosine (B) Urinary excretion of phenylpyruvate and phenyllactate is increased (C) It ... diet (D) It leads to decreased synthesis of thyroid hormones, catecholamines and melanin
Description : A biochemical indication of vitamin B12 deficiency can be obtained by measuring the urinary excretion of (A) Pyruvic acid (B) Malic acid (C) Methyl malonic acid (D) Urocanic acid
Description : Laboratory diagnosis of vitamin B12 deficiency can be made by measuring the urinary excretion of (A) Xanthurenic acid (B) Formiminoglutamic acid (C) Methylmalonic acid (D) Homogentisic acid
Description : An early diagnosis of vitamin C deficiency can be made by (A) Measuring plasma ascorbic acid (B) Measuring urinary ascorbic acid (C) Ascorbic acid saturation test (D) All of these
Description : Vitamin B12 deficiency can be diagnosed by urinary excretion of (A) Pyruvate (B) Methylmalonate (C) Malate (D) Lactate
Description : Answer: a, b, c, d Free oxygen radicals are chemical species that are intermediates in the normal process of cellular respiration. Oxidants that are free radicals have been implicated as initiators of ... a. C-reactive protein b. Serum amyloid c. a -Proteinase inhibitor d. Fibrinogen e. Albumin
Last Answer : Answer: a, b, c, d The acute-phase response is a series of homeostatic responses of the organism to tissue injury in infection and inflammation. After an inflammatory stimulus occurs, a number ... 30% to 50% of the level before injury. The reason for the decrease in production is poorly understood
Description : Bleeding complications are frequently associated with fibrinolytic therapy. Which of the following statement(s) concerning complications of fibrinolytic therapy is/are true? a. Careful monitoring of prothrombin time ... months ago can be treated with fibrinolytic therapy if head CT scan is normal
Last Answer : Answer: b Fibrinolytic therapy induces a hemostatic defect through a combination of factors. Hypofibrinogenemia and fibrin degradation products inhibit fibrin polymerization and, in combination ... is considered a major relative contraindication to either regional or systemic thrombolytic therapy
Description : After operative removal of the parathyroid glands resulting into hypoparathyroidism the concentration of the serum calcium may drop below (A) 11 mg (B) 10 mg (C) 9 mg (D) 7 mg
Description : The product of serum calcium concentration (mg/dl) and serum inorganic phosphorous concentration (mg/dl) is decreased in (A) Rickets (B) Hypoparathyroidism (C) Hyperparathyroidism (D) Renal failure
Description : The product of serum calcium concentration (mg/dl) and serum inorganic phosphorous concentration (mg/dl) in children is about (A) 30 (B) 40 (C) 50 (D) 60
Description : The product of serum calcium concentration (mg/dl) and serum inorganic phosphorous concentration (mg/dl) in adults is about (A) 30 (B) 40 (C) 50 (D) 60