Serum acid phosphatase level is increased in which condition?

Serum acid phosphatase level is increased in which condition?
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Prostate carcinoma.
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Serum acid phosphatase level increases in (A) Metastatic carcinoma of prostate (B) Myocardial infarction (C) Wilson’s disease (D) Liver diseases

Description : Serum acid phosphatase level increases in (A) Metastatic carcinoma of prostate (B) Myocardial infarction (C) Wilson’s disease (D) Liver diseases

Last Answer : Answer : A

Serum alkaline phosphatase is greatly increased in (A) Haemolytic jaundice (B) Hepatic jaundice (C) Obstructive jaundice (D) None of these

Description : Serum alkaline phosphatase is greatly increased in (A) Haemolytic jaundice (B) Hepatic jaundice (C) Obstructive jaundice (D) None of these

Last Answer : Answer : C

All the following statements about obstructive jaundice are true except (A) Prothrombin time may be prolonged due to impaired absorption of vitamin K (B) Serum alkaline phosphatase may be raised due to increased release of the enzyme from liver cells (C) Bile salts may enter systemic circulation due to biliary obstruction (D) There is no defect in conjugation of bilirubin

Description : All the following statements about obstructive jaundice are true except (A) Prothrombin time may be prolonged due to impaired absorption of vitamin K (B) Serum alkaline phosphatase may be raised ... systemic circulation due to biliary obstruction (D) There is no defect in conjugation of bilirubin

Last Answer : Answer : B

Hepatocellular jaundice as compared to pure obstructive type of jaundice is characterized by (A) Increased serum alkaline phosphate, LDH and ALT (B) Decreased serum alkaline phosphatase, LDH and ALT (C) Increased serum alkaline phosphatase and decreased levels of LDH and ALT (D) Decreased serum alkaline phosphatase and increased serum LDH and ALT

Description : Hepatocellular jaundice as compared to pure obstructive type of jaundice is characterized by (A) Increased serum alkaline phosphate, LDH and ALT (B) Decreased serum alkaline phosphatase, LDH and ALT (C ... levels of LDH and ALT (D) Decreased serum alkaline phosphatase and increased serum LDH and ALT

Last Answer : Answer : D

Alkaline phosphatase level in serum is elevated in which conditions?

Description : Alkaline phosphatase level in serum is elevated in which conditions?

Last Answer : Moderate increase is seen in hepatic diseases (infective hepatitis, alcoholic hepatitis). High levels may be noticed in obstructive jaundice or cholestasis. Very high levels are seen in bone diseases such as Pagetís disease, rickets, osteomalacia, osteoblastoma, metastatic carcinoma of bone.

Which of the following enzyme typically elevated in alcoholism? (A) Serum ALP (B) Serum GOT (C) Serum γ-GT (D) Serum acid phosphatase

Description : Which of the following enzyme typically elevated in alcoholism? (A) Serum ALP (B) Serum GOT (C) Serum γ-GT (D) Serum acid phosphatase

Last Answer : Answer : C

The normal serum acid phosphatase activity ranges from (A) 5.0–13.0 KA units/100 ml (B) 1.0–5.0 KA units/100 ml (C) 13.0–18.0 KA units/100 ml (D) 0.2–0.8 KA units/100 ml

Description : The normal serum acid phosphatase activity ranges from (A) 5.0–13.0 KA units/100 ml (B) 1.0–5.0 KA units/100 ml (C) 13.0–18.0 KA units/100 ml (D) 0.2–0.8 KA units/100 ml

Last Answer : Answer : B

An inherited or acquired renal tubular defect in the reabsorption of phosphate (Vit D resistant ricket) is characterized with (A) Normal serum Phosphate (B) High serum phosphate (C) A low blood phosphorous with elevated alkaline Phosphate (D) A high blood phosphorous with decreased alkaline phosphatase

Description : An inherited or acquired renal tubular defect in the reabsorption of phosphate (Vit D resistant ricket) is characterized with (A) Normal serum Phosphate (B) High serum phosphate (C ... blood phosphorous with elevated alkaline Phosphate (D) A high blood phosphorous with decreased alkaline phosphatase

Last Answer : Answer : C

Serum a lka l ine phosphatase leve l increases in (A) Hypothyroidism (B) Carcinoma of prostate (C) Hyperparathyroidism (D) Myocardial ischemia

Description : Serum a lka l ine phosphatase leve l increases in (A) Hypothyroidism (B) Carcinoma of prostate (C) Hyperparathyroidism (D) Myocardial ischemia

Last Answer : Answer : C

The normal serum alkaline phosphatase activity ranges from (A) 1.0–5.0 KA units/100 ml (B) 5.0–13.0 KA units/100 ml (C) 0.8–2.3 KA units/100 ml (D) 13.0–21.0 KA units/100 ml

Description : The normal serum alkaline phosphatase activity ranges from (A) 1.0–5.0 KA units/100 ml (B) 5.0–13.0 KA units/100 ml (C) 0.8–2.3 KA units/100 ml (D) 13.0–21.0 KA units/100 ml

Last Answer : Answer : B

All the following statements about obstructive jaundice are true except (A) Conjugated bilirubin in serum is normal (B) Total bilirubin in serum is raised (C) Bile salts are present in urine (D) Serum alkaline phosphatase is raised

Description : All the following statements about obstructive jaundice are true except (A) Conjugated bilirubin in serum is normal (B) Total bilirubin in serum is raised (C) Bile salts are present in urine (D) Serum alkaline phosphatase is raised

Last Answer : Answer : A

A jaundice in which serum alanine transaminase and alkaline phosphatase are normal is (A) Hepatic jaundice (B) Hemolytic jaundice (C) Parenchymatous jaundice (D) Obstructive Jaundice

Description : A jaundice in which serum alanine transaminase and alkaline phosphatase are normal is (A) Hepatic jaundice (B) Hemolytic jaundice (C) Parenchymatous jaundice (D) Obstructive Jaundice

Last Answer : Answer : B

Serum biochemistry of a 60 year old man revealed calcium of 1.98 mmol/l and phosphate of 0.55 mmol/l with an alkaline phosphatase of 450 IU/l.Which among the following mosts suits with the above serum biochemistry? 1) Osteoporosis 2) Osteomalacia 3) Pagets Disease 4) Secondary Hyperparathyroidism 5) Renal failure

Description : Serum biochemistry of a 60 year old man revealed calcium of 1.98 mmol/l and phosphate of 0.55 mmol/l with an alkaline phosphatase of 450 IU/l.Which among the following mosts suits ... biochemistry? 1) Osteoporosis 2) Osteomalacia 3) Pagets Disease 4) Secondary Hyperparathyroidism 5) Renal failure

Last Answer : Answers-2 Osteomalacia is associated with low calcium and phosphate with raised alkaline phosphatase. Serum biochemistry is normal in osteoporosis. Pagets disease is associated with normal ... renal failure when tertiary hyperparathyroidism sets in there is low calcium with raised phosphate.

One of the causes of hemolytic jaundice is (A) G-6 phosphatase deficiency (B) Increased conjugated bilirubin (C) Glucokinase deficiency (D) Phosphoglucomutase deficiency

Description : One of the causes of hemolytic jaundice is (A) G-6 phosphatase deficiency (B) Increased conjugated bilirubin (C) Glucokinase deficiency (D) Phosphoglucomutase deficiency

Last Answer : Answer : A

An important finding in Hyperammonemia type II is (A) Increased serum gluatmine level (B) Enlarged liver (C) Mental retardation (D) Increased carbamoyl phosphate synthetase level

Description : An important finding in Hyperammonemia type II is (A) Increased serum gluatmine level (B) Enlarged liver (C) Mental retardation (D) Increased carbamoyl phosphate synthetase level

Last Answer : Answer : C

An important finding in glycinuria is (A) Excess excretion of oxalate in the urine (B) Deficiency of enzyme glycinase (C) Significantly increased serum glycine level (D) Defect in renal tubular reabsorption of glycine

Description : An important finding in glycinuria is (A) Excess excretion of oxalate in the urine (B) Deficiency of enzyme glycinase (C) Significantly increased serum glycine level (D) Defect in renal tubular reabsorption of glycine

Last Answer : Answer : D

Creatine kinase (CK) level in serum is increased in which conditions?

Description : Creatine kinase (CK) level in serum is increased in which conditions? 

Last Answer : Myocardial infarction, muscular dystrophies.

Zinc is a cofactor for (A) Acid phosphatase (B) Alkaline phosphatase (C) Amylase (D) Lipase

Description : Zinc is a cofactor for (A) Acid phosphatase (B) Alkaline phosphatase (C) Amylase (D) Lipase

Last Answer : Answer : B

In conversion of lactic acid to glucose, three reactions of glycolytic pathway are circumvented, which of the following enzymes do not participate? (A) Pyruvate carboxylase (B) Phosphoenol pyruvate carboxy kinase (C) Pyruvate kinase (D) Glucose-6-phosphatase

Description : In conversion of lactic acid to glucose, three reactions of glycolytic pathway are circumvented, which of the following enzymes do not participate? (A) Pyruvate carboxylase (B) Phosphoenol pyruvate carboxy kinase (C) Pyruvate kinase (D) Glucose-6-phosphatase

Last Answer : Answer : B

Which of the following is known as bone forming enzyme? (A) Alkaline phosphatase (B) Acid phosphatase (C) Leucine aminopeptidase (D) γ-glutamyl transpeptidase

Description : Which of the following is known as bone forming enzyme? (A) Alkaline phosphatase (B) Acid phosphatase (C) Leucine aminopeptidase (D) γ-glutamyl transpeptidase

Last Answer : Answer : A

All of the following are zinc-containing enzymes except (A) Acid Phosphatase (B) Alkaline Phosphatase (C) Carbonic anhydrase (D) RNA polymerase

Description : All of the following are zinc-containing enzymes except (A) Acid Phosphatase (B) Alkaline Phosphatase (C) Carbonic anhydrase (D) RNA polymerase

Last Answer : Answer : A

The first enzyme found to have isoenzymes was (A) Alkaline Phosphatase (B) Lactate dehydrogenase (C) Acid Phosphatase (D) Creatine kinase

Description : The first enzyme found to have isoenzymes was (A) Alkaline Phosphatase (B) Lactate dehydrogenase (C) Acid Phosphatase (D) Creatine kinase

Last Answer : Answer : B

Amylopectinosis is caused due to absence of (A) Debranching enzyme (B) Branching enzyme (C) Acid maltase (D) Glucose-6-phosphatase

Description : Amylopectinosis is caused due to absence of (A) Debranching enzyme (B) Branching enzyme (C) Acid maltase (D) Glucose-6-phosphatase

Last Answer : Answer : B

The α-ketoacid is decarboxylated by H2O2 forming a carboxylic acid with one carbon atom less in the absence of the enzyme: (A) Catalase (B) Decarboxylase (C) Deaminase (D) Phosphatase

Description : The α-ketoacid is decarboxylated by H2O2 forming a carboxylic acid with one carbon atom less in the absence of the enzyme: (A) Catalase (B) Decarboxylase (C) Deaminase (D) Phosphatase

Last Answer : Answer : A

In conversion of Lactic acid to Glucose, three reactions of Glycolytic pathway are circumvented, which of the following enzymes do not participate? (A) Pyruvate Carboxylase (B) Phosphoenol pyruvate carboxy kinase (C) Pyruvate kinase (D) Glucose-6-phosphatase

Description : In conversion of Lactic acid to Glucose, three reactions of Glycolytic pathway are circumvented, which of the following enzymes do not participate? (A) Pyruvate Carboxylase (B) Phosphoenol pyruvate carboxy kinase (C) Pyruvate kinase (D) Glucose-6-phosphatase

Last Answer : C

Total acid phosphatase may increase in some other conditions also; what are they?

Description : Total acid phosphatase may increase in some other conditions also; what are they?

Last Answer : Prostate carcinoma, secondary metastasis in bones, per rectal examination, intravascular hemolysis.

In the individuals who are given liberal quantities of vitamin C, the serum ascorbic acid level is (A) 1–1.4 µg/100 ml (B) 2–4 µg/100 ml (C) 1–10 µg/100 ml (D) 10–20 µg/100 ml

Description : In the individuals who are given liberal quantities of vitamin C, the serum ascorbic acid level is (A) 1–1.4 µg/100 ml (B) 2–4 µg/100 ml (C) 1–10 µg/100 ml (D) 10–20 µg/100 ml

Last Answer : Answer : A

An Afro-Carribean male aged 48 years presents with gradual onset of exertional dyspnoea, non productive cough, malaise, weight loss and polyarthralgia. Schirmers test indicates a dry eye. X-ray of the hand shows punched out osteopenic lesions. Which of the following investigation is unlikely to be helpful in establishing the diagnosis of this condition: 1) Serum calcium 2) Serum phosphorus 3) Urea and electrolytes 4) Thallium Scan 5) Quantitative Immunoglobulins.

Description : An Afro-Carribean male aged 48 years presents with gradual onset of exertional dyspnoea, non productive cough, malaise, weight loss and polyarthralgia. Schirmers test indicates a dry eye. X-ray ... 2) Serum phosphorus 3) Urea and electrolytes 4) Thallium Scan 5) Quantitative Immunoglobulins.

Last Answer : Answers-4 This condition is sarcoidosis. Serum calcium, Serum phosphorus, Chem7 and Chem 20 and Quantitative Immunoglobulins are all used in establishing the diagnosis. Gallium scan is helpful in ... areas of poor perfusion. It is particularly used in cardiology to detect areas of ischaemia.

A 15-year-old girl was seen by her family physician because of increasing lethargy. She had a recent history of the "flu". Biochemistry tests show that she has renal impairement. serum sodium 140 mmol/L (137 - 144) serum potassium 4.2 mmol/L (3.5 - 4.9) serum urea 28 mol/L (2.5 - 7.5) serum creatinine 280 µmol/L (60 - 110) Her condition does not improve after several weeks on corticosteroid therapy, so a renal biopsy is performed. The biopsy demonstrates the presence of segmental sclerosis of 3 of 10 glomeruli identified in the biopsy specimen. Immunofluorescence studies and electron microscopy do not reveal evidence for immune deposits. What is the most appropriate advice to give regarding her condition? 1) She has an underlying malignancy 2) She may require a renal transplant in 10 years

Description : A 15-year-old girl was seen by her family physician because of increasing lethargy. She had a recent history of the "flu". Biochemistry tests show that she has renal impairement. ... will likely develop a restrictive lung disease 5) She will probably improve with additional corticosteroid therapy

Last Answer : Answers-2 The findings point to focal segmental glomerulosclerosis (FSGS), which leads to chronic renal failure in half of cases. The lack of resolution with corticosteroid therapy and the progression to chronic renal failure is what sets FSGS apart from minimal change disease.

Bleeding complications are frequently associated with fibrinolytic therapy. Which of the following statement(s) concerning complications of fibrinolytic therapy is/are true? a. Careful monitoring of prothrombin time and aPTT time are necessary to avoid bleeding complications b. A level of serum fibrinogen less than 100 mg/dl is associated with an increased risk of bleeding c. Recent (less than 10 days) major surgery is a contraindication to systemic but not regional fibrinolytic therapy d. A patient with a cerebrovascular event occurring less than two months ago can be treated with fibrinolytic therapy if head CT scan is normal

Description : Bleeding complications are frequently associated with fibrinolytic therapy. Which of the following statement(s) concerning complications of fibrinolytic therapy is/are true? a. Careful monitoring of prothrombin time ... months ago can be treated with fibrinolytic therapy if head CT scan is normal

Last Answer : Answer: b Fibrinolytic therapy induces a hemostatic defect through a combination of factors. Hypofibrinogenemia and fibrin degradation products inhibit fibrin polymerization and, in combination ... is considered a major relative contraindication to either regional or systemic thrombolytic therapy

The age related physiological change in geriatric patient which may affect drug distribution is a) Increased body mass. b) Increased total body water. c) Increased total body fat. d) Increased serum albumin level.

Description : The age related physiological change in geriatric patient which may affect drug distribution is a) Increased body mass. b) Increased total body water. c) Increased total body fat. d) Increased serum albumin level.

Last Answer : b) Increased total body water. 

An increased serum ‘Iron’ and decreased ‘Fe’ binding capacity are found in (A) Fe-deficiency anaemia (B) Sideroblastic anaemia (C) Thalassaemia (D) Anaemia of chromic disorders

Description : An increased serum ‘Iron’ and decreased ‘Fe’ binding capacity are found in (A) Fe-deficiency anaemia (B) Sideroblastic anaemia (C) Thalassaemia (D) Anaemia of chromic disorders

Last Answer : Answer : B

In Vitamin D poisoning (hyper-vitaminosis) (A) Both serum and urinary “Ca” (B) The serum Ca is low and urinary calcium high (C) The serum “Ca” is increased and urinary “Ca” is normal (D) Both serum and urinary “Ca” are low

Description : In Vitamin D poisoning (hyper-vitaminosis) (A) Both serum and urinary “Ca” (B) The serum Ca is low and urinary calcium high (C) The serum “Ca” is increased and urinary “Ca” is normal (D) Both serum and urinary “Ca” are low

Last Answer : Answer : A

An increased serum iron and decreased iron binding capacity is found in (A) Fe deficiency anemia (B) Sideroblastic anemia (C) Folate deficiency anemia (D) Sickle cell anemia

Description : An increased serum iron and decreased iron binding capacity is found in (A) Fe deficiency anemia (B) Sideroblastic anemia (C) Folate deficiency anemia (D) Sickle cell anemia

Last Answer : Answer : B

Levels of serum calcium and inorganic phosphorus are increased in (A) Hypervitaminosis D (B) Hypoparathyroidism (C) Hypovitaminosis D (D) None of these

Description : Levels of serum calcium and inorganic phosphorus are increased in (A) Hypervitaminosis D (B) Hypoparathyroidism (C) Hypovitaminosis D (D) None of these

Last Answer : Answer : A

Increased serum ornithine carabamoyl transferase activity is diagnostic of (A) Myocardial infarction (B) Hemolytic jaundice (C) Bone disease (D) Acute viral hepatitis

Description : Increased serum ornithine carabamoyl transferase activity is diagnostic of (A) Myocardial infarction (B) Hemolytic jaundice (C) Bone disease (D) Acute viral hepatitis

Last Answer : Answer : D

Increased serum alanine during fasting is due to (A) Breakdown of muscle proteins (B) Decreased utilization of non essential amino acids (C) Leakage of aminoacids to plasma (D) Impaired renal function

Description : Increased serum alanine during fasting is due to (A) Breakdown of muscle proteins (B) Decreased utilization of non essential amino acids (C) Leakage of aminoacids to plasma (D) Impaired renal function

Last Answer : Answer : A

Serum lipase is increased in (A) Acute parotitis (B) Acute pancreatitis (C) Infective hepatitis (D) Biliary obstruction

Description : Serum lipase is increased in (A) Acute parotitis (B) Acute pancreatitis (C) Infective hepatitis (D) Biliary obstruction

Last Answer : Answer : A

Serum amylase is increased in (A) Acute parotitis (B) Acute pancreatitis (C) Pancreatic cancer (D) All of these

Description : Serum amylase is increased in (A) Acute parotitis (B) Acute pancreatitis (C) Pancreatic cancer (D) All of these

Last Answer : Answer : B

Serum LDL has been found to be increased in (A) Obstructive jaundice (B) Hepatic jaundice (C) Hemolytic jaundice (D) Malabsorption syndrome

Description : Serum LDL has been found to be increased in (A) Obstructive jaundice (B) Hepatic jaundice (C) Hemolytic jaundice (D) Malabsorption syndrome

Last Answer : Answer : A

Which one of the following is true of IgE? 1) Is present in plasma in the same concentration as IgG 2) Is increased acutely in an asthmatic attack 3) Crosses the normal placenta 4) Is increased in the serum of atopic individuals 5) Is involved in type 2 hypersensitivity

Description : Which one of the following is true of IgE? 1) Is present in plasma in the same concentration as IgG 2) Is increased acutely in an asthmatic attack 3) Crosses the normal placenta 4) Is increased in the serum of atopic individuals 5) Is involved in type 2 hypersensitivity

Last Answer : Answers-4 IgG is the predominant form of immunoglobulin in plasma at a concentration around 10,000 times that of IgE. IgG crosses the placenta to confer immunity to the fetus but IgE does ... frequently increased in those with atopy but serum IgE does not rise acutely during an asthmatic attack.

cAMD is destroyed by (A) Adenylate cyclase (B) Phosphodiesterase (C) Synthetase phosphatase (D) Synthetase kinase

Description : cAMD is destroyed by (A) Adenylate cyclase (B) Phosphodiesterase (C) Synthetase phosphatase (D) Synthetase kinase

Last Answer : Answer : B

Glucocorticoids increase the synthesis of all of the following except (A) Glucokinase (B) Glucose-6-phosphatase (C) Fructose-1, 6-biphosphatase (D) Pyruvate carboxylase

Description : Glucocorticoids increase the synthesis of all of the following except (A) Glucokinase (B) Glucose-6-phosphatase (C) Fructose-1, 6-biphosphatase (D) Pyruvate carboxylase

Last Answer : Answer : A

Hyperglycemic effect of glucocorticoids is due to (A) Inactivation of protein phosphatase (B) Inactivation of fructose 1,6-biphosphatase (C) Stimulation of synthesis of pyruvate carboxylase (D) Stimulation of synthesis of eltroxykinase

Description : Hyperglycemic effect of glucocorticoids is due to (A) Inactivation of protein phosphatase (B) Inactivation of fructose 1,6-biphosphatase (C) Stimulation of synthesis of pyruvate carboxylase (D) Stimulation of synthesis of eltroxykinase

Last Answer : Answer : C

Calcitriol facilitates calcium absorption by increasing the synthesis of the following in intestinal mucosa: (A) Calcium Binding Protein (B) Alkaline Phosphatase (C) Calcium-dependent ATPase (D) All of these

Description : Calcitriol facilitates calcium absorption by increasing the synthesis of the following in intestinal mucosa: (A) Calcium Binding Protein (B) Alkaline Phosphatase (C) Calcium-dependent ATPase (D) All of these

Last Answer : Answer : D

Cobalt may act as cofactor for the enzyme: (A) Glycl-glycine dipeptidase (B) Elastase (C) Polynucleotidases (D) Phosphatase

Description : Cobalt may act as cofactor for the enzyme: (A) Glycl-glycine dipeptidase (B) Elastase (C) Polynucleotidases (D) Phosphatase

Last Answer : Answer : A

The enzyme that converts glucose to glucose-6-phosphate is (A) Phosphatase (B) Hexokinase (C) Phosphorylase (D) Glucose synthetase

Description : The enzyme that converts glucose to glucose-6-phosphate is (A) Phosphatase (B) Hexokinase (C) Phosphorylase (D) Glucose synthetase

Last Answer : Answer : B

Which one of the following enzymes requires a coenzyme derived from the vitamin whose structure is shown below? (A) Enoyl CoA hydratase (B) Phosphofructokinase (C) Glucose-6-phosphatase (D) Glucose-6-phosphate dehydrogenase

Description : Which one of the following enzymes requires a coenzyme derived from the vitamin whose structure is shown below? (A) Enoyl CoA hydratase (B) Phosphofructokinase (C) Glucose-6-phosphatase (D) Glucose-6-phosphate dehydrogenase

Last Answer : Answer : D

Glucose-6-phosphatase and PEP carboxy kinase are regulated by (A) Covalent modification (B) Allosteric regulation (C) Induction and repression (D) All of these

Description : Glucose-6-phosphatase and PEP carboxy kinase are regulated by (A) Covalent modification (B) Allosteric regulation (C) Induction and repression (D) All of these

Last Answer : Answer : C

Alkaline phosphatase is present in (A) Liver (B) Bones (C) Intestinal mucosa (D) All of these

Description : Alkaline phosphatase is present in (A) Liver (B) Bones (C) Intestinal mucosa (D) All of these

Last Answer : Answer : D