Total acid phosphatase may increase in some other conditions also; what are they?

Total acid phosphatase may increase in some other conditions also; what are they?
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Prostate carcinoma, secondary metastasis in bones, per rectal examination, intravascular hemolysis.
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Alkaline phosphatase level in serum is elevated in which conditions?

Description : Alkaline phosphatase level in serum is elevated in which conditions?

Last Answer : Moderate increase is seen in hepatic diseases (infective hepatitis, alcoholic hepatitis). High levels may be noticed in obstructive jaundice or cholestasis. Very high levels are seen in bone diseases such as Pagetís disease, rickets, osteomalacia, osteoblastoma, metastatic carcinoma of bone.

Glucocorticoids increase the synthesis of all of the following except (A) Glucokinase (B) Glucose-6-phosphatase (C) Fructose-1, 6-biphosphatase (D) Pyruvate carboxylase

Description : Glucocorticoids increase the synthesis of all of the following except (A) Glucokinase (B) Glucose-6-phosphatase (C) Fructose-1, 6-biphosphatase (D) Pyruvate carboxylase

Last Answer : Answer : A

All the following statements about obstructive jaundice are true except (A) Conjugated bilirubin in serum is normal (B) Total bilirubin in serum is raised (C) Bile salts are present in urine (D) Serum alkaline phosphatase is raised

Description : All the following statements about obstructive jaundice are true except (A) Conjugated bilirubin in serum is normal (B) Total bilirubin in serum is raised (C) Bile salts are present in urine (D) Serum alkaline phosphatase is raised

Last Answer : Answer : A

Cobalt may act as cofactor for the enzyme: (A) Glycl-glycine dipeptidase (B) Elastase (C) Polynucleotidases (D) Phosphatase

Description : Cobalt may act as cofactor for the enzyme: (A) Glycl-glycine dipeptidase (B) Elastase (C) Polynucleotidases (D) Phosphatase

Last Answer : Answer : A

All the following statements about obstructive jaundice are true except (A) Prothrombin time may be prolonged due to impaired absorption of vitamin K (B) Serum alkaline phosphatase may be raised due to increased release of the enzyme from liver cells (C) Bile salts may enter systemic circulation due to biliary obstruction (D) There is no defect in conjugation of bilirubin

Description : All the following statements about obstructive jaundice are true except (A) Prothrombin time may be prolonged due to impaired absorption of vitamin K (B) Serum alkaline phosphatase may be raised ... systemic circulation due to biliary obstruction (D) There is no defect in conjugation of bilirubin

Last Answer : Answer : B

Zinc is a cofactor for (A) Acid phosphatase (B) Alkaline phosphatase (C) Amylase (D) Lipase

Description : Zinc is a cofactor for (A) Acid phosphatase (B) Alkaline phosphatase (C) Amylase (D) Lipase

Last Answer : Answer : B

In conversion of lactic acid to glucose, three reactions of glycolytic pathway are circumvented, which of the following enzymes do not participate? (A) Pyruvate carboxylase (B) Phosphoenol pyruvate carboxy kinase (C) Pyruvate kinase (D) Glucose-6-phosphatase

Description : In conversion of lactic acid to glucose, three reactions of glycolytic pathway are circumvented, which of the following enzymes do not participate? (A) Pyruvate carboxylase (B) Phosphoenol pyruvate carboxy kinase (C) Pyruvate kinase (D) Glucose-6-phosphatase

Last Answer : Answer : B

Which of the following enzyme typically elevated in alcoholism? (A) Serum ALP (B) Serum GOT (C) Serum γ-GT (D) Serum acid phosphatase

Description : Which of the following enzyme typically elevated in alcoholism? (A) Serum ALP (B) Serum GOT (C) Serum γ-GT (D) Serum acid phosphatase

Last Answer : Answer : C

Which of the following is known as bone forming enzyme? (A) Alkaline phosphatase (B) Acid phosphatase (C) Leucine aminopeptidase (D) γ-glutamyl transpeptidase

Description : Which of the following is known as bone forming enzyme? (A) Alkaline phosphatase (B) Acid phosphatase (C) Leucine aminopeptidase (D) γ-glutamyl transpeptidase

Last Answer : Answer : A

All of the following are zinc-containing enzymes except (A) Acid Phosphatase (B) Alkaline Phosphatase (C) Carbonic anhydrase (D) RNA polymerase

Description : All of the following are zinc-containing enzymes except (A) Acid Phosphatase (B) Alkaline Phosphatase (C) Carbonic anhydrase (D) RNA polymerase

Last Answer : Answer : A

The first enzyme found to have isoenzymes was (A) Alkaline Phosphatase (B) Lactate dehydrogenase (C) Acid Phosphatase (D) Creatine kinase

Description : The first enzyme found to have isoenzymes was (A) Alkaline Phosphatase (B) Lactate dehydrogenase (C) Acid Phosphatase (D) Creatine kinase

Last Answer : Answer : B

Amylopectinosis is caused due to absence of (A) Debranching enzyme (B) Branching enzyme (C) Acid maltase (D) Glucose-6-phosphatase

Description : Amylopectinosis is caused due to absence of (A) Debranching enzyme (B) Branching enzyme (C) Acid maltase (D) Glucose-6-phosphatase

Last Answer : Answer : B

Serum acid phosphatase level increases in (A) Metastatic carcinoma of prostate (B) Myocardial infarction (C) Wilson’s disease (D) Liver diseases

Description : Serum acid phosphatase level increases in (A) Metastatic carcinoma of prostate (B) Myocardial infarction (C) Wilson’s disease (D) Liver diseases

Last Answer : Answer : A

The normal serum acid phosphatase activity ranges from (A) 5.0–13.0 KA units/100 ml (B) 1.0–5.0 KA units/100 ml (C) 13.0–18.0 KA units/100 ml (D) 0.2–0.8 KA units/100 ml

Description : The normal serum acid phosphatase activity ranges from (A) 5.0–13.0 KA units/100 ml (B) 1.0–5.0 KA units/100 ml (C) 13.0–18.0 KA units/100 ml (D) 0.2–0.8 KA units/100 ml

Last Answer : Answer : B

The α-ketoacid is decarboxylated by H2O2 forming a carboxylic acid with one carbon atom less in the absence of the enzyme: (A) Catalase (B) Decarboxylase (C) Deaminase (D) Phosphatase

Description : The α-ketoacid is decarboxylated by H2O2 forming a carboxylic acid with one carbon atom less in the absence of the enzyme: (A) Catalase (B) Decarboxylase (C) Deaminase (D) Phosphatase

Last Answer : Answer : A

In conversion of Lactic acid to Glucose, three reactions of Glycolytic pathway are circumvented, which of the following enzymes do not participate? (A) Pyruvate Carboxylase (B) Phosphoenol pyruvate carboxy kinase (C) Pyruvate kinase (D) Glucose-6-phosphatase

Description : In conversion of Lactic acid to Glucose, three reactions of Glycolytic pathway are circumvented, which of the following enzymes do not participate? (A) Pyruvate Carboxylase (B) Phosphoenol pyruvate carboxy kinase (C) Pyruvate kinase (D) Glucose-6-phosphatase

Last Answer : C

Serum acid phosphatase level is increased in which condition?

Description : Serum acid phosphatase level is increased in which condition?

Last Answer : Prostate carcinoma.

cAMD is destroyed by (A) Adenylate cyclase (B) Phosphodiesterase (C) Synthetase phosphatase (D) Synthetase kinase

Description : cAMD is destroyed by (A) Adenylate cyclase (B) Phosphodiesterase (C) Synthetase phosphatase (D) Synthetase kinase

Last Answer : Answer : B

Hyperglycemic effect of glucocorticoids is due to (A) Inactivation of protein phosphatase (B) Inactivation of fructose 1,6-biphosphatase (C) Stimulation of synthesis of pyruvate carboxylase (D) Stimulation of synthesis of eltroxykinase

Description : Hyperglycemic effect of glucocorticoids is due to (A) Inactivation of protein phosphatase (B) Inactivation of fructose 1,6-biphosphatase (C) Stimulation of synthesis of pyruvate carboxylase (D) Stimulation of synthesis of eltroxykinase

Last Answer : Answer : C

Calcitriol facilitates calcium absorption by increasing the synthesis of the following in intestinal mucosa: (A) Calcium Binding Protein (B) Alkaline Phosphatase (C) Calcium-dependent ATPase (D) All of these

Description : Calcitriol facilitates calcium absorption by increasing the synthesis of the following in intestinal mucosa: (A) Calcium Binding Protein (B) Alkaline Phosphatase (C) Calcium-dependent ATPase (D) All of these

Last Answer : Answer : D

Serum alkaline phosphatase is greatly increased in (A) Haemolytic jaundice (B) Hepatic jaundice (C) Obstructive jaundice (D) None of these

Description : Serum alkaline phosphatase is greatly increased in (A) Haemolytic jaundice (B) Hepatic jaundice (C) Obstructive jaundice (D) None of these

Last Answer : Answer : C

An inherited or acquired renal tubular defect in the reabsorption of phosphate (Vit D resistant ricket) is characterized with (A) Normal serum Phosphate (B) High serum phosphate (C) A low blood phosphorous with elevated alkaline Phosphate (D) A high blood phosphorous with decreased alkaline phosphatase

Description : An inherited or acquired renal tubular defect in the reabsorption of phosphate (Vit D resistant ricket) is characterized with (A) Normal serum Phosphate (B) High serum phosphate (C ... blood phosphorous with elevated alkaline Phosphate (D) A high blood phosphorous with decreased alkaline phosphatase

Last Answer : Answer : C

The enzyme that converts glucose to glucose-6-phosphate is (A) Phosphatase (B) Hexokinase (C) Phosphorylase (D) Glucose synthetase

Description : The enzyme that converts glucose to glucose-6-phosphate is (A) Phosphatase (B) Hexokinase (C) Phosphorylase (D) Glucose synthetase

Last Answer : Answer : B

Which one of the following enzymes requires a coenzyme derived from the vitamin whose structure is shown below? (A) Enoyl CoA hydratase (B) Phosphofructokinase (C) Glucose-6-phosphatase (D) Glucose-6-phosphate dehydrogenase

Description : Which one of the following enzymes requires a coenzyme derived from the vitamin whose structure is shown below? (A) Enoyl CoA hydratase (B) Phosphofructokinase (C) Glucose-6-phosphatase (D) Glucose-6-phosphate dehydrogenase

Last Answer : Answer : D

Glucose-6-phosphatase and PEP carboxy kinase are regulated by (A) Covalent modification (B) Allosteric regulation (C) Induction and repression (D) All of these

Description : Glucose-6-phosphatase and PEP carboxy kinase are regulated by (A) Covalent modification (B) Allosteric regulation (C) Induction and repression (D) All of these

Last Answer : Answer : C

Alkaline phosphatase is present in (A) Liver (B) Bones (C) Intestinal mucosa (D) All of these

Description : Alkaline phosphatase is present in (A) Liver (B) Bones (C) Intestinal mucosa (D) All of these

Last Answer : Answer : D

Alkaline phosphatase is present in (A) Liver (B) Bones (C) Placenta (D) All of these

Description : Alkaline phosphatase is present in (A) Liver (B) Bones (C) Placenta (D) All of these

Last Answer : Answer : D

The enzyme glucose 6-phosphatase is present in (A) Liver (B) Muscle (C) Adipose tissue (D) Brain

Description : The enzyme glucose 6-phosphatase is present in (A) Liver (B) Muscle (C) Adipose tissue (D) Brain

Last Answer : Answer : A

Pompe ’s d isease is caused due to deficiency of (A) Lysosomal α-1→4 and 1→6-glucosidase (B) Glucose-6-phosphatase (C) Glycogen synthase (D) Phosphofructokinase

Description : Pompe ’s d isease is caused due to deficiency of (A) Lysosomal α-1→4 and 1→6-glucosidase (B) Glucose-6-phosphatase (C) Glycogen synthase (D) Phosphofructokinase

Last Answer : Answer : A

Von Gierke’s disease is characterized by the deficiency of (A) Glucose-6-phosphatase (B) α -1→ 4 Glucosidase (C) 1→ 6 Glucosidase (D) Liver phosphorylase

Description : Von Gierke’s disease is characterized by the deficiency of (A) Glucose-6-phosphatase (B) α -1→ 4 Glucosidase (C) 1→ 6 Glucosidase (D) Liver phosphorylase

Last Answer : Answer : A

The enzyme glucose-6-phosphatase which catalyses the conversion of glucose 6-phosphate to glucose is not found in (A) Liver (B) Muscle (C) Intestine (D) Kidney

Description : The enzyme glucose-6-phosphatase which catalyses the conversion of glucose 6-phosphate to glucose is not found in (A) Liver (B) Muscle (C) Intestine (D) Kidney

Last Answer : Answer : B

Serum a lka l ine phosphatase leve l increases in (A) Hypothyroidism (B) Carcinoma of prostate (C) Hyperparathyroidism (D) Myocardial ischemia

Description : Serum a lka l ine phosphatase leve l increases in (A) Hypothyroidism (B) Carcinoma of prostate (C) Hyperparathyroidism (D) Myocardial ischemia

Last Answer : Answer : C

The normal serum alkaline phosphatase activity ranges from (A) 1.0–5.0 KA units/100 ml (B) 5.0–13.0 KA units/100 ml (C) 0.8–2.3 KA units/100 ml (D) 13.0–21.0 KA units/100 ml

Description : The normal serum alkaline phosphatase activity ranges from (A) 1.0–5.0 KA units/100 ml (B) 5.0–13.0 KA units/100 ml (C) 0.8–2.3 KA units/100 ml (D) 13.0–21.0 KA units/100 ml

Last Answer : Answer : B

The hydrolysis of glucose-6-PO4 is catalyzed by a phosphatase that is not found in which of the following? (A) Liver (B) Kidney (C) Muscle (D) Small intestine

Description : The hydrolysis of glucose-6-PO4 is catalyzed by a phosphatase that is not found in which of the following? (A) Liver (B) Kidney (C) Muscle (D) Small intestine

Last Answer : Answer : C

Hepatocellular jaundice as compared to pure obstructive type of jaundice is characterized by (A) Increased serum alkaline phosphate, LDH and ALT (B) Decreased serum alkaline phosphatase, LDH and ALT (C) Increased serum alkaline phosphatase and decreased levels of LDH and ALT (D) Decreased serum alkaline phosphatase and increased serum LDH and ALT

Description : Hepatocellular jaundice as compared to pure obstructive type of jaundice is characterized by (A) Increased serum alkaline phosphate, LDH and ALT (B) Decreased serum alkaline phosphatase, LDH and ALT (C ... levels of LDH and ALT (D) Decreased serum alkaline phosphatase and increased serum LDH and ALT

Last Answer : Answer : D

A jaundice in which serum alanine transaminase and alkaline phosphatase are normal is (A) Hepatic jaundice (B) Hemolytic jaundice (C) Parenchymatous jaundice (D) Obstructive Jaundice

Description : A jaundice in which serum alanine transaminase and alkaline phosphatase are normal is (A) Hepatic jaundice (B) Hemolytic jaundice (C) Parenchymatous jaundice (D) Obstructive Jaundice

Last Answer : Answer : B

One of the causes of hemolytic jaundice is (A) G-6 phosphatase deficiency (B) Increased conjugated bilirubin (C) Glucokinase deficiency (D) Phosphoglucomutase deficiency

Description : One of the causes of hemolytic jaundice is (A) G-6 phosphatase deficiency (B) Increased conjugated bilirubin (C) Glucokinase deficiency (D) Phosphoglucomutase deficiency

Last Answer : Answer : A

The “Primaquin sensitivity types of haemolytic anaemia has been found to relate to reduced R.B.C activity of which enzyme? (A) Pyruvate kinase deficiency (B) Glucose-6-phosphatase deficiency (C) Glucose-6-p dehydrogenase deficiency (D) Hexokinase deficiency

Description : The “Primaquin sensitivity types of haemolytic anaemia has been found to relate to reduced R.B.C activity of which enzyme? (A) Pyruvate kinase deficiency (B) Glucose-6-phosphatase deficiency (C) Glucose-6-p dehydrogenase deficiency (D) Hexokinase deficiency

Last Answer : C

The hydrolysis of Glucose-6-P is catalysed by a phosphatase that is not formed in which of the following? (A) Liver (B) Kidney (C) Muscle (D) Small intestine

Description : The hydrolysis of Glucose-6-P is catalysed by a phosphatase that is not formed in which of the following? (A) Liver (B) Kidney (C) Muscle (D) Small intestine

Last Answer : C

The hydrolysis of Glucose-6-phosphate is catalysed by a specific phosphatase which is found only in (A) Liver, intestines and kidneys (B) Brain, spleen and adrenals (C) Striated muscle (D) Plasma

Description : The hydrolysis of Glucose-6-phosphate is catalysed by a specific phosphatase which is found only in (A) Liver, intestines and kidneys (B) Brain, spleen and adrenals (C) Striated muscle (D) Plasma

Last Answer : A

Glycogen is converted to glucose-1- phosphate by (A) UDPG transferase (B) Branching enzyme (C) Phosphorylase (D) Phosphatase

Description : Glycogen is converted to glucose-1- phosphate by (A) UDPG transferase (B) Branching enzyme (C) Phosphorylase (D) Phosphatase

Last Answer : C

The following enzyme is required for the hexose monophosphate shunt pathway: (A) Glucose-6-phosphatase (B) Phosphorylase (C) Aldolase (D) Glucose-6-phosphate dehydrogenase

Description : The following enzyme is required for the hexose monophosphate shunt pathway: (A) Glucose-6-phosphatase (B) Phosphorylase (C) Aldolase (D) Glucose-6-phosphate dehydrogenase

Last Answer : D

The following is an enzyme required for glycolysis: (A) Pyruvate kinase (B) Pyruvate carboxylase (C) Glucose-6-phosphatase (D) Glycerokinase

Description : The following is an enzyme required for glycolysis: (A) Pyruvate kinase (B) Pyruvate carboxylase (C) Glucose-6-phosphatase (D) Glycerokinase

Last Answer : A

Ethanol decreases gluconeogenesis by (A) Inhibiting glucose-6-phosphatase (B) Inhibiting PEP carboxykinase (C) Converting NAD+ into NADH and decreasing the availability of pyruvate (D) Converting NAD+ into NADH and decreasing the availability of lactate

Description : Ethanol decreases gluconeogenesis by (A) Inhibiting glucose-6-phosphatase (B) Inhibiting PEP carboxykinase (C) Converting NAD+ into NADH and decreasing the availability of pyruvate (D) Converting NAD+ into NADH and decreasing the availability of lactate

Last Answer : C

McArdle’s disease is due to the deficiency of (A) Glucose-6-phosphatase (B) Phosphofructokinase (C) Liver phosphorylase (D) muscle phosphorylase

Description : McArdle’s disease is due to the deficiency of (A) Glucose-6-phosphatase (B) Phosphofructokinase (C) Liver phosphorylase (D) muscle phosphorylase

Last Answer : D

Glucose-6-phosphatase is absent or deficient in (A) Von Gierke’s disease (B) Pompe’s disease (C) Cori’s disease (D) McArdle’s disease

Description : Glucose-6-phosphatase is absent or deficient in (A) Von Gierke’s disease (B) Pompe’s disease (C) Cori’s disease (D) McArdle’s disease

Last Answer : A

Glucose-6-phosphatase is not present in (A) Liver and kidneys (B) Kidneys and muscles (C) Kidneys and adipose tissue (D) Muscles and adipose tissue

Description : Glucose-6-phosphatase is not present in (A) Liver and kidneys (B) Kidneys and muscles (C) Kidneys and adipose tissue (D) Muscles and adipose tissue

Last Answer : D

A 19 year-old female is referred following a visit to the dentist where marked erosion of her teeth was noted. She was entirely asymptomatic and her only medication was the oral contraceptive pill. On examination her blood pressure was 110/70 mmHg and her body mass index was 21.5 kg/m2 (18 - 25). Investigations sodium 135 mmol/l potassium 2.1 mmol/l bicarbonate 42 mmol/l urea 2.6 mol/L corrected calcium 2.08 mmol/ alkaline phosphatase 201 iu/l (50-110) What is the most likely diagnosis? 1) Bulimia nervosa 2) Conn's syndrome 3) Laxative abuse 4) Pregnancy 5) Primary hypoparathyroidism

Description : A 19 year-old female is referred following a visit to the dentist where marked erosion of her teeth was noted. She was entirely asymptomatic and her only medication was the oral contraceptive pill ... ) Bulimia nervosa 2) Conn's syndrome 3) Laxative abuse 4) Pregnancy 5) Primary hypoparathyroidism

Last Answer : Answers-5 This patient has tooth erosion associated with hypokalaemic metabolic alkalosis and hypocalcaemia. This suggests a diagnosis of hypoparathyroidism. Conn's is unlikely in this age group, is ... raised alkaline phosphatase would not be expected. Early pregnancy would not fit this picture.

Serum biochemistry of a 60 year old man revealed calcium of 1.98 mmol/l and phosphate of 0.55 mmol/l with an alkaline phosphatase of 450 IU/l.Which among the following mosts suits with the above serum biochemistry? 1) Osteoporosis 2) Osteomalacia 3) Pagets Disease 4) Secondary Hyperparathyroidism 5) Renal failure

Description : Serum biochemistry of a 60 year old man revealed calcium of 1.98 mmol/l and phosphate of 0.55 mmol/l with an alkaline phosphatase of 450 IU/l.Which among the following mosts suits ... biochemistry? 1) Osteoporosis 2) Osteomalacia 3) Pagets Disease 4) Secondary Hyperparathyroidism 5) Renal failure

Last Answer : Answers-2 Osteomalacia is associated with low calcium and phosphate with raised alkaline phosphatase. Serum biochemistry is normal in osteoporosis. Pagets disease is associated with normal ... renal failure when tertiary hyperparathyroidism sets in there is low calcium with raised phosphate.