Serum acid phosphatase level increases in (A) Metastatic carcinoma of prostate (B) Myocardial infarction (C) Wilson’s disease (D) Liver diseases

Serum acid phosphatase level increases in (A) Metastatic carcinoma of prostate (B) Myocardial infarction (C) Wilson’s disease (D) Liver diseases
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Serum a lka l ine phosphatase leve l increases in (A) Hypothyroidism (B) Carcinoma of prostate (C) Hyperparathyroidism (D) Myocardial ischemia

Description : Serum a lka l ine phosphatase leve l increases in (A) Hypothyroidism (B) Carcinoma of prostate (C) Hyperparathyroidism (D) Myocardial ischemia

Last Answer : Answer : C

The isoenzymes LDH5 is elevated in (A) Myocardial infarction (B) Peptic ulcer (C) Liver disease (D) Infectious diseases

Description : The isoenzymes LDH5 is elevated in (A) Myocardial infarction (B) Peptic ulcer (C) Liver disease (D) Infectious diseases

Last Answer : Answer : C

Serum AST activity is not characteristically elevated as the result of (A) Myocardial infarction (B) Passive congestion of liver (C) Muscular dystrophies (D) Peptic ulcer

Description : Serum AST activity is not characteristically elevated as the result of (A) Myocardial infarction (B) Passive congestion of liver (C) Muscular dystrophies (D) Peptic ulcer

Last Answer : Answer : D

Health benefits afforded by the combined estrogenprogestin oral contraceptive pill include the following except: A. Reduced menstrual blood loss B. Lower risk of fibrocystic breast disease C. Lower risk of myocardial infarction D. Lower risk of endometrial carcinoma

Description : Health benefits afforded by the combined estrogenprogestin oral contraceptive pill include the following except: A. Reduced menstrual blood loss B. Lower risk of fibrocystic breast disease C. Lower risk of myocardial infarction D. Lower risk of endometrial carcinoma

Last Answer : . Lower risk of myocardial infarction

Increased serum ornithine carabamoyl transferase activity is diagnostic of (A) Myocardial infarction (B) Hemolytic jaundice (C) Bone disease (D) Acute viral hepatitis

Description : Increased serum ornithine carabamoyl transferase activity is diagnostic of (A) Myocardial infarction (B) Hemolytic jaundice (C) Bone disease (D) Acute viral hepatitis

Last Answer : Answer : D

Serum ferroxidase level decreases in (A) Gaucher’s disease (B) Cirrhosis of liver (C) Acute pancreatitis (D) Wilson’s disease ENZYMES 143

Description : Serum ferroxidase level decreases in (A) Gaucher’s disease (B) Cirrhosis of liver (C) Acute pancreatitis (D) Wilson’s disease ENZYMES 143

Last Answer : Answer : D

Creatine phosphokinase isoenzyme is a marker for (A) Kidney disease (B) Liver disease (C) Myocardial infarction (D) None of these

Description : Creatine phosphokinase isoenzyme is a marker for (A) Kidney disease (B) Liver disease (C) Myocardial infarction (D) None of these

Last Answer : Answer : C

LDH1 and LDH2 are elevated in (A) Myocardial infarction (B) Liver disease (C) Kidney disease (D) Brain disease

Description : LDH1 and LDH2 are elevated in (A) Myocardial infarction (B) Liver disease (C) Kidney disease (D) Brain disease

Last Answer : Answer : A

Addition of a progestin for 10-12 days each month to estrogen replacement therapy in menopausal women is recommended because the progestin: A. Blocks the increased risk of myocardial infarction due to estrogen B. Blocks the increased risk of endometrial carcinoma due to estrogen C. Reverses vulval atrophy occurring in postmenopausal women D. Enhances the metabolic benefits of estrogen treatment

Description : Addition of a progestin for 10-12 days each month to estrogen replacement therapy in menopausal women is recommended because the progestin: A. Blocks the increased risk of myocardial ... vulval atrophy occurring in postmenopausal women D. Enhances the metabolic benefits of estrogen treatment

Last Answer : The estrogen commonly used for hormone replacement therapy in menopausal women is: A. Ethinylestradiol B. Estradiol benzoate C. Diethylstilbestrol D. Conjugated estrogens

On which day following acute myocardial infarction the estimation of serum AST will be of greatest significance? (A) First day (B) Second day (C) Third day (D) Fourth day

Description : On which day following acute myocardial infarction the estimation of serum AST will be of greatest significance? (A) First day (B) Second day (C) Third day (D) Fourth day

Last Answer : Answer : B

On the third day following onset of acute myocardial infarction, which enzyme estimation will have the best predictive value? (A) Serum AST (B) Serum CK (C) Serum ALT (D) Serum LDH

Description : On the third day following onset of acute myocardial infarction, which enzyme estimation will have the best predictive value? (A) Serum AST (B) Serum CK (C) Serum ALT (D) Serum LDH

Last Answer : Answer : D

Which of the following isoenzyme of lactate dehydrogenase is raised in serum in myocardial infarction: (A) LD1 (B) LD2 (C) LD1 and LD2 (D) LD5

Description : Which of the following isoenzyme of lactate dehydrogenase is raised in serum in myocardial infarction: (A) LD1 (B) LD2 (C) LD1 and LD2 (D) LD5

Last Answer : Answer : C

From the following myocardial infarction, the earliest serum enzyme to rise is (A) Creatine Kinase (B) GOT (C) GPT (D) LDH

Description : From the following myocardial infarction, the earliest serum enzyme to rise is (A) Creatine Kinase (B) GOT (C) GPT (D) LDH

Last Answer : Answer : A

Which of the following serum enzyme rises in myocardial infarction: (A) Creatine kinase (B) GOT (C) LDH (D) All of these

Description : Which of the following serum enzyme rises in myocardial infarction: (A) Creatine kinase (B) GOT (C) LDH (D) All of these

Last Answer : Answer : D

Serum lactate dehydrogenase rises in (A) Viral hepatitis (B) Myocardial infarction (C) Carcinomatosis (D) All of these

Description : Serum lactate dehydrogenase rises in (A) Viral hepatitis (B) Myocardial infarction (C) Carcinomatosis (D) All of these

Last Answer : Answer : D

On the third day of onset of acute myocardial infarction the enzyme elevated is (A) Serum AST (B) Serum CK (C) Serum LDH (D) Serum ALT

Description : On the third day of onset of acute myocardial infarction the enzyme elevated is (A) Serum AST (B) Serum CK (C) Serum LDH (D) Serum ALT

Last Answer : Answer : C

Serum gamma glutamyl transpeptidase is raised in (A) Haemolytic jaundice (B) Myocardial infarction (C) Alcoholic hepatitis (D) Acute cholecystitis

Description : Serum gamma glutamyl transpeptidase is raised in (A) Haemolytic jaundice (B) Myocardial infarction (C) Alcoholic hepatitis (D) Acute cholecystitis

Last Answer : Answer : C

What are the serum enzymes helpful in the diagnosis of myocardial infarction?

Description : What are the serum enzymes helpful in the diagnosis of myocardial infarction?

Last Answer : Lactate dehydrogenase (LDH) H4 iso-enzyme, creatine kinase (CK) CK MB iso-enzyme and aspartyl transaminase (AST).

A 65-year old patient has colon carcinoma metastatic to the liver and lungs. He has had a weight loss of 10 kg. Cytokine-dependent tumor cachexia is attributable to which of the following? a. Increased glucose uptake and increased glycogen breakdown occur in this circumstance. b. Suppressed activity of lipoprotein lipase results from TNFa c. TNFa stimulates lipolysis d. The differentiation process of pre-adipocytes is impaired e. Partial reversal of differentiated adipocytes to pre-adipocyte morphology and gene expression occurs

Description : A 65-year old patient has colon carcinoma metastatic to the liver and lungs. He has had a weight loss of 10 kg. Cytokine-dependent tumor cachexia is attributable to which of the ... is impaired e. Partial reversal of differentiated adipocytes to pre-adipocyte morphology and gene expression occurs

Last Answer : Answer: a, b, c, d, e Tumor cachexia appears to be mediated by TNFa. Lipopolysaccharide (LPS), as well as other cytokines, activate a variety of inflammatory cells, most ... chronic syndromes of anorexia, weight loss, and cachexia that are associated with both chronic infection and malignancy

The isozyme CK-MB is specifically increased in the blood of patients who had (A) Skeletal muscle disease (B) Recent myocardial infarction (C) Infective hepatitis (D) Myxoedema

Description : The isozyme CK-MB is specifically increased in the blood of patients who had (A) Skeletal muscle disease (B) Recent myocardial infarction (C) Infective hepatitis (D) Myxoedema

Last Answer : Answer : B

All the following statements about Wilson’s disease are correct except (A) It is a genetic disease (B) The defect involves copper-dependent P-type ATPase (C) Copper is deposited in liver, basal ganglia and around cornea (D) Plasma copper level is increased in it

Description : All the following statements about Wilson’s disease are correct except (A) It is a genetic disease (B) The defect involves copper-dependent P-type ATPase (C) Copper is deposited in liver, basal ganglia and around cornea (D) Plasma copper level is increased in it

Last Answer : Answer : D

All the following statements about obstructive jaundice are true except (A) Prothrombin time may be prolonged due to impaired absorption of vitamin K (B) Serum alkaline phosphatase may be raised due to increased release of the enzyme from liver cells (C) Bile salts may enter systemic circulation due to biliary obstruction (D) There is no defect in conjugation of bilirubin

Description : All the following statements about obstructive jaundice are true except (A) Prothrombin time may be prolonged due to impaired absorption of vitamin K (B) Serum alkaline phosphatase may be raised ... systemic circulation due to biliary obstruction (D) There is no defect in conjugation of bilirubin

Last Answer : Answer : B

Serum acid phosphatase level is increased in which condition?

Description : Serum acid phosphatase level is increased in which condition?

Last Answer : Prostate carcinoma.

If a fibrinolytic drug is used for treatment of acute myocardial infarction, the adverse drug effect that is most likely to occur is (a) Acute renal failure (b) Development of antiplatelet antibodies (c) Encephalitis secondary to liver dysfunction (d) Hemorrhagic stroke (e) Neutropenia

Description : If a fibrinolytic drug is used for treatment of acute myocardial infarction, the adverse drug effect that is most likely to occur is (a) Acute renal failure (b) Development of antiplatelet antibodies (c) Encephalitis secondary to liver dysfunction (d) Hemorrhagic stroke (e) Neutropenia

Last Answer : Ans: D

Serum biochemistry of a 60 year old man revealed calcium of 1.98 mmol/l and phosphate of 0.55 mmol/l with an alkaline phosphatase of 450 IU/l.Which among the following mosts suits with the above serum biochemistry? 1) Osteoporosis 2) Osteomalacia 3) Pagets Disease 4) Secondary Hyperparathyroidism 5) Renal failure

Description : Serum biochemistry of a 60 year old man revealed calcium of 1.98 mmol/l and phosphate of 0.55 mmol/l with an alkaline phosphatase of 450 IU/l.Which among the following mosts suits ... biochemistry? 1) Osteoporosis 2) Osteomalacia 3) Pagets Disease 4) Secondary Hyperparathyroidism 5) Renal failure

Last Answer : Answers-2 Osteomalacia is associated with low calcium and phosphate with raised alkaline phosphatase. Serum biochemistry is normal in osteoporosis. Pagets disease is associated with normal ... renal failure when tertiary hyperparathyroidism sets in there is low calcium with raised phosphate.

Ceruloplasmin is absent in (A) Cirrhosis of liver (B) Wilson’s disease (C) Menke’s disease (D) Copper deficiency

Description : Ceruloplasmin is absent in (A) Cirrhosis of liver (B) Wilson’s disease (C) Menke’s disease (D) Copper deficiency

Last Answer : Answer : B

Alkaline phosphatase level in serum is elevated in which conditions?

Description : Alkaline phosphatase level in serum is elevated in which conditions?

Last Answer : Moderate increase is seen in hepatic diseases (infective hepatitis, alcoholic hepatitis). High levels may be noticed in obstructive jaundice or cholestasis. Very high levels are seen in bone diseases such as Pagetís disease, rickets, osteomalacia, osteoblastoma, metastatic carcinoma of bone.

Which of the following enzyme typically elevated in alcoholism? (A) Serum ALP (B) Serum GOT (C) Serum γ-GT (D) Serum acid phosphatase

Description : Which of the following enzyme typically elevated in alcoholism? (A) Serum ALP (B) Serum GOT (C) Serum γ-GT (D) Serum acid phosphatase

Last Answer : Answer : C

The normal serum acid phosphatase activity ranges from (A) 5.0–13.0 KA units/100 ml (B) 1.0–5.0 KA units/100 ml (C) 13.0–18.0 KA units/100 ml (D) 0.2–0.8 KA units/100 ml

Description : The normal serum acid phosphatase activity ranges from (A) 5.0–13.0 KA units/100 ml (B) 1.0–5.0 KA units/100 ml (C) 13.0–18.0 KA units/100 ml (D) 0.2–0.8 KA units/100 ml

Last Answer : Answer : B

The slow moving fraction of LDH is typically increased in pancreas with (A) Cerebrovascular accidents (B) Acute myocardial infarction (C) Acute pancreatitis (D) Acute viral hepatits

Description : The slow moving fraction of LDH is typically increased in pancreas with (A) Cerebrovascular accidents (B) Acute myocardial infarction (C) Acute pancreatitis (D) Acute viral hepatits

Last Answer : Answer : D

What is the advantage of cardiac troponin I over other parameters to identify the myocardial infarction?

Description : What is the advantage of cardiac troponin I over other parameters to identify the myocardial infarction?

Last Answer : Cardiac Troponin I is released into the blood within four hours after the onset of cardiac symptoms, peaks at 12-16 hours and remains elevated for 5-9 days post-infarction. Therefore, CTI is ... marker at any time interval after the heart attack. It is 75% sensitive index for myocardial infarction.

What is the advantage of CK estimation over LDH estimation to identify myocardial infarction?

Description : What is the advantage of CK estimation over LDH estimation to identify myocardial infarction?

Last Answer : The CK level starts to rise within three hours of infarction. Therefore, CK estimation is very useful to detect early cases, where ECG changes may be ambiguous. The CK level is not increased in hemolysis or in congestive cardiac failure; and therefore CK has an advantage over LDH.

How do you further investigate for myocardial infarction?

Description : How do you further investigate for myocardial infarction?

Last Answer : LDH-1 (H4) iso-enzyme is increased.

The liver enzyme which is sensitive indicator of liver cell injury and is most helpful in recognizing acute hepatocellular diseases is Options: 1) Alkaline Phosphatase 2) Aspartate aminotransferase 3) Gamma glutamyl Transpeptidase 4) Creatine Phosphokinase

Description : The liver enzyme which is sensitive indicator of liver cell injury and is most helpful in recognizing acute hepatocellular diseases is Options: 1) Alkaline Phosphatase 2) Aspartate aminotransferase 3) Gamma glutamyl Transpeptidase 4) Creatine Phosphokinase

Last Answer : Correct Answer: 2) Aspartate aminotransferase

Von Gierke’s disease is characterized by the deficiency of (A) Glucose-6-phosphatase (B) α -1→ 4 Glucosidase (C) 1→ 6 Glucosidase (D) Liver phosphorylase

Description : Von Gierke’s disease is characterized by the deficiency of (A) Glucose-6-phosphatase (B) α -1→ 4 Glucosidase (C) 1→ 6 Glucosidase (D) Liver phosphorylase

Last Answer : Answer : A

McArdle’s disease is due to the deficiency of (A) Glucose-6-phosphatase (B) Phosphofructokinase (C) Liver phosphorylase (D) muscle phosphorylase

Description : McArdle’s disease is due to the deficiency of (A) Glucose-6-phosphatase (B) Phosphofructokinase (C) Liver phosphorylase (D) muscle phosphorylase

Last Answer : D

It is said that nucleotide phosphatase (NTP) is a better index of obstructive liver disease than alkaline phosphatase (ALP), why?

Description : It is said that nucleotide phosphatase (NTP) is a better index of obstructive liver disease than alkaline phosphatase (ALP), why?

Last Answer : ALP level is increased in both liver and bone diseases, but NTP is only in liver diseases. 

Serum TSH levels are high in most cases of: A. Myxoedema B. Grave’s disease C. Carcinoma thyroid D. Toxic nodular goiter

Description : Serum TSH levels are high in most cases of: A. Myxoedema B. Grave’s disease C. Carcinoma thyroid D. Toxic nodular goiter

Last Answer : A. Increases vascularity

.19 Serum TSH levels are high in most cases of: A. Myxoedema B. Grave’s disease C. Carcinoma thyroid D. Toxic nodular goiter

Description : .19 Serum TSH levels are high in most cases of: A. Myxoedema B. Grave’s disease C. Carcinoma thyroid D. Toxic nodular goiter

Last Answer : A. Myxoedema

Oral contraceptive use increases the risk of occurrence of the following diseases except: A. Hypertension B. Leg vein thrombosis C. Endometrial carcinoma D. Gall stones

Description : Oral contraceptive use increases the risk of occurrence of the following diseases except: A. Hypertension B. Leg vein thrombosis C. Endometrial carcinoma D. Gall stones

Last Answer : C. Endometrial carcinoma

In Wilson’s disease (A) Copper fails to be excreted in the bile (B) Copper level in plasma is decreased (C) Ceruloplasmin level is increased (D) Intestinal absorption of copper is decreased

Description : In Wilson’s disease (A) Copper fails to be excreted in the bile (B) Copper level in plasma is decreased (C) Ceruloplasmin level is increased (D) Intestinal absorption of copper is decreased

Last Answer : Answer : A

Serum alkaline phosphatase is greatly increased in (A) Haemolytic jaundice (B) Hepatic jaundice (C) Obstructive jaundice (D) None of these

Description : Serum alkaline phosphatase is greatly increased in (A) Haemolytic jaundice (B) Hepatic jaundice (C) Obstructive jaundice (D) None of these

Last Answer : Answer : C

An inherited or acquired renal tubular defect in the reabsorption of phosphate (Vit D resistant ricket) is characterized with (A) Normal serum Phosphate (B) High serum phosphate (C) A low blood phosphorous with elevated alkaline Phosphate (D) A high blood phosphorous with decreased alkaline phosphatase

Description : An inherited or acquired renal tubular defect in the reabsorption of phosphate (Vit D resistant ricket) is characterized with (A) Normal serum Phosphate (B) High serum phosphate (C ... blood phosphorous with elevated alkaline Phosphate (D) A high blood phosphorous with decreased alkaline phosphatase

Last Answer : Answer : C

The normal serum alkaline phosphatase activity ranges from (A) 1.0–5.0 KA units/100 ml (B) 5.0–13.0 KA units/100 ml (C) 0.8–2.3 KA units/100 ml (D) 13.0–21.0 KA units/100 ml

Description : The normal serum alkaline phosphatase activity ranges from (A) 1.0–5.0 KA units/100 ml (B) 5.0–13.0 KA units/100 ml (C) 0.8–2.3 KA units/100 ml (D) 13.0–21.0 KA units/100 ml

Last Answer : Answer : B

All the following statements about obstructive jaundice are true except (A) Conjugated bilirubin in serum is normal (B) Total bilirubin in serum is raised (C) Bile salts are present in urine (D) Serum alkaline phosphatase is raised

Description : All the following statements about obstructive jaundice are true except (A) Conjugated bilirubin in serum is normal (B) Total bilirubin in serum is raised (C) Bile salts are present in urine (D) Serum alkaline phosphatase is raised

Last Answer : Answer : A

Hepatocellular jaundice as compared to pure obstructive type of jaundice is characterized by (A) Increased serum alkaline phosphate, LDH and ALT (B) Decreased serum alkaline phosphatase, LDH and ALT (C) Increased serum alkaline phosphatase and decreased levels of LDH and ALT (D) Decreased serum alkaline phosphatase and increased serum LDH and ALT

Description : Hepatocellular jaundice as compared to pure obstructive type of jaundice is characterized by (A) Increased serum alkaline phosphate, LDH and ALT (B) Decreased serum alkaline phosphatase, LDH and ALT (C ... levels of LDH and ALT (D) Decreased serum alkaline phosphatase and increased serum LDH and ALT

Last Answer : Answer : D

A jaundice in which serum alanine transaminase and alkaline phosphatase are normal is (A) Hepatic jaundice (B) Hemolytic jaundice (C) Parenchymatous jaundice (D) Obstructive Jaundice

Description : A jaundice in which serum alanine transaminase and alkaline phosphatase are normal is (A) Hepatic jaundice (B) Hemolytic jaundice (C) Parenchymatous jaundice (D) Obstructive Jaundice

Last Answer : Answer : B

Serum lipase level increases in (A) Paget’s disease (B) Gaucher’s disease (C) Acute pancreatitis (D) Diabetes mellitus

Description : Serum lipase level increases in (A) Paget’s disease (B) Gaucher’s disease (C) Acute pancreatitis (D) Diabetes mellitus

Last Answer : Answer : C

Assertion `:` Myocardial infarction oftern results from a sudden decrease in coronary blood supply resulting in decreased oxygen supply. Reason `:` Th

Description : Assertion `:` Myocardial infarction oftern results from a sudden decrease in coronary blood supply resulting in decreased oxygen supply. Reason `:` Th

Last Answer : Assertion `:` Myocardial infarction oftern results from a sudden decrease in coronary blood supply ... If both Assertion & Reason are false.

Most fatal thrombosis leading to myocardial infarction is of

Description : Most fatal thrombosis leading to myocardial infarction is of

Last Answer : Most fatal thrombosis leading to myocardial infarction is of A. Right circumflex coronary ... descending artery D. Left circumflex coronary artery