Description : The synthesis of fatty acids is often termed reductive synthesis. (A) NADP+ (B) NADH (C) FADH2 (D) NADPH
Last Answer : Answer : D
Description : Pentose phosphate pathway is of significance because it generates (A) NADPH for reductive synthesis (B) Regenerates glucose 6-phosphate (C) Generates fructose 6-phosphate (D) Forms glyceraldehyde 3-phosphate
Last Answer : Answer : A
Description : Apart from reductive synthesis, NADPH is used for what purpose?
Last Answer : It is necessary to keep the integrity of RBC membrane, it is needed for keeping glutathione in reduced state, it is required for keeping transparency of lens, it is necessary for superoxide production inside macrophages.
Description : A metabolite which is common to pathways of cholesterol biosynthesis from acetyl-CoA and cholecalciferol formation from cholesterol is (A) Zymosterol (B) Lumisterol (C) Ergosterol (D) 7 Dehydrocholesterol
Description : The cyclooxygenase isoenzymes COX-1 and COX-2 differ from each other in that (a) They catalyse different pathways in prostanoid biosynthesis (b) COX–1 is inhibited by aspirin but not COX–2 (c) COX–2 is inhibited by ibuprofen but not COX–1 (d) COX–1 is constitutive while COX–2 is inducible
Last Answer : Ans: D
Description : The cyclooxygenase isoenzymes COX-1 and COX-2 differ from each other in that: A. They catalyse different pathways in prostanoid biosynthesis B. COX-1 is inhibited by aspirin but not COX-2 C. COX-2 is inhibited by ibuprofen but not COX-1 D. COX-1 is constitutive while COX-2 is largely
Last Answer : D. COX-1 is constitutive while COX-2 is largely
Description : A metabolic pathways is a (A) Route taken by chemicals (B) Sequence of enzyme facilitated chemical reactions (C) Route taken by an enzyme from one reaction to another (D) Sequence of origin of organic molecules
Last Answer : Answer : B
Description : In most metabolic pathways, all needed enzymes are arranged together in a multienzyme complex within a (A) Solution of ATP (B) Membrane (C) Quanternary protein (D) Coenzyme
Description : Most major metabolic pathways are considered mainly either anabolic or catabolic. Which of the following pathway is most correctly considered to be amphibolic? (A) Citric acid cycle (B) Gluconeogenesis (C) Lipolysis (D) Glycolysis
Description : Most of the metabolic pathways are either anabolic or catabolic. Which of the following pathways is considered as “amphibolic” in nature? (A) Glycogenesis (B) Glycolytic pathway (C) Lipolysis (D) TCA cycle
Last Answer : D
Description : What are the pathways inhibited by insulin?
Last Answer : Gluconeogenesis, glycogenolysis, lipolysis, ketogenesis.
Description : What are the pathways stimulated by insulin?
Last Answer : Glycolysis, glycogen synthesis, HMP shunt pathway, lipogenesis.
Description : `C_(3)` cycle (reductive pentose phosphate cycle) is basically a
Last Answer : `C_(3)` cycle (reductive pentose phosphate cycle) is basically a A. `CO_(2)` reduction cycle B. ` ... C. Photochemical reaction D. Both (2) and (3)
Description : Calvin cycle is: (1) C3 cycle (2) Reductive pentose-phosphate cycle (3) Common in cereals uncommon in cereals (4) Uncommon in cereals
Last Answer : Ans. ((c))
Description : Photosynthesis is a process (a) Reductive and exergonic (b) Reductive and catabolic (c) Reductive, endergonic and catabolic (d) Reductive, endergonic and anabolic
Last Answer : Ans:(d)
Description : Lysosome contains (a) oxidative enzymes (b) hydrolytic enzymes (c) reductive enzymes (d) anabolic enzymes
Last Answer : (b) hydrolytic enzymes
Description : The following coenzyme is required for catabolism of pyrimidine bases: (A) NADH (B) NADPH (C) FADH2 (D) None of these
Description : Conversion of uridine diphosphate into deoxyuridine diphosphate requires all the following except (A) Ribonucleotide reductase (B) Thioredoxin (C) Tetrahydrobiopterin (D) NADPH
Last Answer : Answer : C
Description : Reduction of ribonucleotide diphosphates (NDPs) to their corresponding deoxy ribonucleotide diphosphates (dNDPs) involves (A) FMN (B) FAD (C) NAD (D) NADPH
Description : Thyroproxidase requires hydrogen peroxide as oxidizing agent. The H2O2 is produced by (A) FADH2 dependent enzyme (B) NADH dependent enzyme (C) NADP dependent enzyme (D) NADPH dependent enzyme
Description : The number of ATP produced in the oxidation of 1 molecule of NADPH in oxidative phosphorylation is (A) Zero (B) 2 (C) 3 (D) 4
Description : Pantothenic acid acts on (A) NADP (B) NADPH (C) FAD (D) CoA
Description : β-oxidation of fatty acids is inhibited by (A) NADPH (B) Acetyl CoA (C) Malonyl CoA (D) None of these
Description : For reduction enzyme HMG-CoA reductase requires cofactor: (A) NADPH (B) NADP (C) NAD (D) FAD
Description : Synthesis of sphingosine requires the cofactor (A) NAD (B) NADP (C) NADPH+ (D) ATP
Description : The main source of reducing equivalents (NADPH) for lipogenesis is (A) Pentose phosphate pathway (B) Citric acid cycle (C) Glycolysis (D) Glycogenolysis
Description : Erythrocytes under normal conditions and microorganisms under anaerobic conditions may accumulate (A) NADPH (B) Pyruvate (C) Phosphoenolpyruvate (D) Lactate
Description : Retinal is reduced to retinol by retinene reductase in presence of the coenzyme (A) NAD+ (B) NADP+ (C) NADH + H+ (D) NADPH + H+
Description : Conversion of all-trans-retinal into alltrans-retinol requires (A) NAD (B) NADH (C) NADP (D) NADPH
Description : Conversion of retinal into ritonal requires the presence of (A) NADH (B) NADPH (C) FADH2 (D) Lipoic acid
Description : Conversion of folate into tetrahydrofolate requires (A) NADH (B) NADPH (C) FMNH2 (D) FADH2
Description : Retinol and retinal are interconverted requiring dehydrogenase or reductase in the presence of (A) NAD or NADP (B) NADH + H+ (C) NADPH (D) FAD
Description : Retinal is reduced to retinol in intestinal mucosa by a specific retinaldehyde reductase utilising (A) NADPH + H+ (B) FAD (C) NAD (D) NADH + H+
Description : A pathway that requires NADPH as a cofactor is (A) Extramitochondrial folic acid synthesis (B) Ketone body formation (C) Glycogenesis (D) Gluconeogenesis
Description : A pathway that requires NADPH as a cofactor is (A) Fatty acid oxidation (B) Extra mitochondrial denovo fatty acid synthesis (C) Ketone bodies formation (D) Glycogenesis
Description : NADPH is produced when this enzyme acts (A) Pyruvate dehydrogenase (B) Malic enzyme (C) Succinate dehydrogenase (D) Malate dehydrogenase
Description : A soluble system for synthesis of fatty acids have been isolated from avian liver, required for the formation of long chain fatty acids by this system is (A) ATP (B) Acetyl CoA (C) NADPH (D) All of these
Description : Mitochondrial lipogenesis requires (A) bicarbonate (B) biotin (C) acetyl CoA carboxylase (D) NADPH
Description : NADPH required for fatty acid synthesis can come from (A) Hexose monophosphate shunt (B) Oxidative decarboxylation of malate (C) Extramitochondrial oxidation of isocitrate (D) All of these
Description : For synthesis of sphingosine, all the following coenzymes are required except (A) Pyridoxal phosphate (B) NADPH (C) FAD (D) NAD
Description : Which of the following is required as a reductant in fatty acid synthesis? (A) NADH (B) NADPH (C) FADH2 (D) FMNH2
Description : Reduced glutathione functions in R.B.Cs to (A) Produce NADPH (B) Reduce methemoglobin to hemoglobin (C) Produce NADH (D) Reduce oxidizing agents such as H2O2
Description : Two important byproducts of HMP shunt are (A) NADH and pentose sugars (B) NADPH and pentose sugars (C) Pentose sugars and 4 membered sugars (D) Pentose sugars and sedoheptulose
Last Answer : B
Description : What are the sources of NADPH for fatty acid synthesis?
Last Answer : Glucose-6-phosphate dehydrogenase, malic enzyme, cytoplasmic malate dehydrogenase.
Description : What are the steps in which NADPH is used in fatty acid synthesis?
Last Answer : Step 4 (Keto acyl reductase) and Step 6 (Enoyl reductase).
Description : How NADPH is made available?
Last Answer : In the HMP shunt pathway, glucose-6-phosphate dehydrogenase reaction produces NADPH.
Description : Apart from NADPH generation, is there any other purpose for the HMPshunt pathway?
Last Answer : The pathway is required for the synthesis of ribose, the pentose phosphates are necessary for nucleotide (DNA and RNA) synthesis.
Description : What about ATP generation? NADPH is used for that?
Last Answer : No. NADPH is not used for ATP generation.
Description : What is the use of NADPH in biological systems?
Last Answer : For reductive biosynthesis.
Description : Which enzyme generates NADPH?
Last Answer : Glucose-6-phosphate dehydrogenase.